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현진해(Jin Hai Hyun),김열홍(Yeul Hong Kim),송태진(Tae Jin Song),진윤태(Yoon Tae Jeen),박현철(Hyun Chul Park),김재선(Jae Seon Kim),박종재(Jong Jae Park) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.1
Behcet's disease is a multisystem disorder presenting with recurrent oral and genital ulceration as well as uveitis often leading to blindness. While intestinal Behcets disease most commonly affects the ileocecal region, esophageal involvement is v ry uncommon. A 42-year-old male patient was admitted to Haewha hospital because of dysphagia. There was a history of recurrent aphthous stomatitis and genital ulcers. Irregularly marginated ulcer surrounded with hyperermic edematous mucosa was found at mid esophagus in the gastrofiberscopic examination. The pathologic finding was chronic ulcerative inflammation with vasculitis. So he was diagnosed to have Behcet's disease and treated with steroid. We report a case of esophageal Behcet's disease which had been diagnosed by gastrofiberscopy and reviewed literature briefly.
전통 약용식물 및 각종 식물의 항암 효과에 대한 연구 (III)
현진원,임경화,성민숙,강삼식,백우현,배건우,조현,김형자,우은란,박호군,박재갑,양용만,Hyun, Jin-Won,Lim, Kyoung-Hwa,Sung, Min-Sook,Kang, Sam-Sik,Paik, Woo-Hyun,Bae, Kun-Woo,Cho, Hyun,Kim, Hyoung-Ja,Woo, Eun-Rhan,Park, Ho-Koon,Park, Jae-Gah 한국생약학회 1996 생약학회지 Vol.27 No.2
Antineoplastic activity against human gastric and colon carcinoma cell lines was tested in eighty-three species of Korean plants including Korean medicinal plants which have been frequently used in oriental herb prescriptions. The plant materials were extracted with methanol and the cytotoxic activity was tested using a calorimetric tetrazolium assay (MTT assay). Twenty-six plant extracts against gastric carcinoma cell line, eighteen extracts against colon carcinoma cell line and fourteen plant extracts against both carcinoma cell lines showed antineoplastic activity at the concentration of less than $100{\mu}g/ml$. The effective components from four species have been isolated and reported.
현진원,임경화,신진이,성민숙,원용진,김영식,강삼식,장일무,우원식,백우현,김형자,우은란,박호군,박재갑,Hyun, Jin-Won,Lim, Kyoung-Hwa,Shin, Jin-E,Sung, Min-Sook,Won, Yong-Jin,Kim, Yeong-Shik,Kang, Sam-Sik,Chang, Il-Moo,Woo, Won-Sick,Paik, Woo-Hyun 한국생약학회 1994 생약학회지 Vol.25 No.2
Antineoplastic activity against human gastric and colon carcinoma cell lines was measured in 100 extracts from 90 plants using MTT (3-[4,5-dimethyl thiazo-2-yl]-2, 5-diphenyl tetrazolium bromide) method. Four extracts from four plants have been reported to have antineoplastic effect. Extracts from remaining 86 plants failed to show significant cytotoxic effect at the concentration of less than $230\;{\mu}/ml$.
현진해(Jin Hai Hyun),송치욱(Chi Wook song),김열홍(Yeul Hong Kim),심경보(Kyung Bo Sim) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.2
Tuberculosis of stomach is very rare disease and diagnosis is difficult without histologic examination. This study is a case report of tuberculosis of the stomach, of which diagnosis was confirmed by histologic finding of biopsy specimen obtained from the site of ulceration and cytologic finding of sonoguided fine needle aspiration from the intraabdominal mass. Patient is a 50-year-old female who was admitted with a chief complaint of poor appetite and weight loss. Submucosal tumor and ulceration was found at antrum of the stomach by both endoscopy and upper GI study. Multiple cystic masses were found at periaortic, retroperitoneal and pancreatic area by sonogram and CT scan. Histologic finding of biopsied specimen and cytologic finding of aspirated tissue was compatible with that of tuberculosis. Administration of antituberculous agent resulted in good response.