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- 저자 : 허세호(Se Ho Huh) (검색결과 8 건)
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김동익,허세호,이병붕,김은숙,문지영,황지혜 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1
Purpose: Given the increased frequency of operative therapy and radiation therapy on breast cancers and uterine cancers, there is very little information on lymphedema associated with these treatments in Korea. Thus, the authors conducted this study to describe and analyze the data which they had obtained from the patients. Method: A retrospective study was undertaken on 840 patients who registered to the Lymphedema Clinic of Samsung Seoul Hospital throughout the period of February 1995 to August 2001. Result: Out of 840 patients, 205 patients (24%) were confirmed as having primary lymphedema, while 635 patients (76%) had secondary lymphedema. The ratio of male to female for primary lymphedema was 1 :1.8(Male : Female), while secondary lymphedema demonstrated to be 1:21 (Male : Female), demonstrating a female preponderance. Secondary lymphedema mostly developed after undergoing treatment for uterine cancer (341 patients, 53.7%) and breast cancer (226 patients, 35.5%) The lesions of occurrence for both primary and secondary lymphedema were mainly in the lower extremities than the upper extremities. In regards to the degree of clinical edema, a large number of the patients, that is 633 patients (76%) had progressed to Stage Ⅱ~Ⅲ. Among the patients who developed edema after undergoing treatment for cancers, only 43 patients (7%) were provided information on the possibility of developing lymphedema, while the majority of the patients had no knowledge about this possibility. When the patients' subjective experiences were investigated on the degree of the edema, there was no significant increase in pain despite an increase in the degree of the edema (P<0.05), nevertheless, a significant increase was found in cosmetic problems (P>0.05). Conclusion: As a general rule, complete recovery from chronic lymphedema is not expected. However, early detection of lymphedema and timely appropriate treatment as well as aggressive patient education on lymphedema and its related complications can prevent its progression.
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김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1
As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.
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김동익,이윤신,김덕경,허세호,이병붕,김지은 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1
Purpose: Small calibered prosthetic vascular grafts are prone to low patency rates after bypass surgery due to its high thrombogenicity and neointimal hyperplasia. Endothelial cells are known to inhibit thrombus formations, platelet aggregation and smooth muscle cells proliteration. The purpose of this study was to examine the development of autologous endothelial cell seeded prosthetic vascular graft. Method: The autologous endothelial cells (ECs) were harvested from canine external jugular veins. Approximately 5*10^4 ECs were obtained through passage 5 to 6 under the static condition. The cultured ECs were seeded into the polytetrafluoroethylenc (PTFE) graft and cultured for 3 days before implanting into the canine carotid artery.The PTFE graft was harvested at 6 weeks after implantation. Result: The primary cultured ECs were treated with Factor VⅢ/WF, CD3]/PECAM-1 antibodyand confirmed with fluorescence micrograph, The gratf patency rates were 2/6 (33%) in the control gratf and 5/6 (83%) in the ECs seeded graft at 6 weeks after implantation. the entire luminal surface of the EC seeded graft was covered with ECs. Only the vicinity of the anastomosis site was covered with ECs in the control graft. Conclusion: This is a pilot study for the development of autologous endothelial cell seeded prosthetic vascular graft. The results of our study demonstrate that the endothelialized PTFE are better than ninendothelialized PTFE.
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유소영,박찬영,정석,김동익,이병붕,허세호,한동철,장준근 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2
Purpose: The spreading, orientation, and chemotaxis the gradient of a chemoattractant of smooth muscle cells (SMCs) were studied on the micro-grooved substrata by the light, fluorescence and scanning electron microscopy. Method: Vertical-walled grooves were produced in silicon wafers by the micromachining technique. All grooves were 4~20㎛ deep and 10~80㎛ wide, SMCs were cultured on each microgroove and examined under stereo-microscope. Result: Cell clusters were markedly oriented by all the grooved substrata examined. Tim-lapse images acquired from CCD (Charge Coupled Device) showed that the grooves directed the migration of SMCs. There was no prominent difference in the migration speed of SMCs according to the grooves. All the cytoskeletal fibers were reoragnized in the same direction with grooves. Especially the alignments of microtubule and intermediate filaments were distinguished in the SMCs on the micro grooves. Conclusion: These results could be applied to the analysis of vascular restenosis and the development of artificial blood vessels.
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Rhabdomyolysis in Aortic Surgery : case report 증례 보고
Huh, Se-Ho,Kim, Dong-Ik,Kang, Sin-Jae,Lee, Byung-Boong 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2
횡문근융해는 마취과정이나 수술시 환자의 체위 및 수술시간에 따라 발생할 수 있다고 보고된다. 혈관 외과적 수술시 주요혈관이 일시적으로 차단된 상황에서 긴 수술시간에 따라 국소적인 허혈 증상이 나타날 가능성은 충분히 있다. 그러나, 횡문근 융해현상이 보고된 예는 많지 않다. 저자들은 복부 대동맥류 수술 직후 편측 둔부에 심한 종창이 발생되고, 동측 하지에 운동장애가 발생되었던 횡문근 융해증 2예를 경험하였다. 1예는 파열된 복부대동맥류로 응급 수술을 시행한 후였고, 1예는 정규수술 후였다. 치료는 다량의 수액공급과 이뇨제 사용 및 소변을 알칼리화 시키는 등의 보존적 치료로 급성 신부전 등의 합병증 없이 회복 되었다. Rhabdomyolysis is an uncommon complication in a vascular surgery. Recently we experienced two cases of rhabdomyolysis after aortic surgery. The first one underwent an elective surgery for AAA but the 2nd case performed and emergency surgery because of ruptured AAA. Both patients recovered from rhabdomyolysis by conservative medical treatment without any major complications such as acute renal failure.
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파열된 복부대동맥류의 생존율에 영향을 미치는 요인에 대한 임상적 고찰
김동익,이병붕,김익희,허세호,이순정 대한혈관외과학회 2001 Vascular Specialist International Vol.17 No.2
Purpose: Ruptured abdominal aortic aneurysm (RAAA) continue to be a significant causes of death. We review 14 patients who underwent repair of RAAA to analyze the factors affecting the mortality rate. Method: Fourteen patients who underwent repair of a RAAA at Samsung Medical Center from March 1995 to July 2001 were reviewed retrospectively. The patients were divided two groups as survival and fatal group. Data was analyzed by both univariate and multivariate analysis. Result: There were nine patients (64%) in survival group and five patients (36%) in fatal group. The mean age of survival group was 64.67±19.59 years and 67.0±5.15 years in fatal group. All patients in fatal group were died within 2 days postoperatively. By univariate analysis of various factors associated with the mortality rate, creatinine level, hemoglobin level were statistically significant. Other factors associated with the mortality rate, albumin, initial systolic blood pressure, initial diastolic blood pressure, operation time, prothrombin time and perioperative platelet count were not statistically significant. Conclusion: These findings suggest that creatinine level is predictive of death in repair of RAAA. But patients who have RAAA should not be denied therapy on the basis of any specific criteria of preoperative factors.
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