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최혜준,강수지,홍광원 한국응용생명화학회 2017 Applied Biological Chemistry (Appl Biol Chem) Vol.60 No.5
In this study, we compared the toxin gene expression, NheA toxin production, doubling time, and viable cell number for several strains of the food poisoning bacteria Bacillus cereus and the microbial pesticide Bacillus thuringiensis. The two B. cereus and six B. thuringiensis strains evaluated were confirmed to possess and transcribe the nheABC, hblCDA, and cytK genes using polymerase chain reaction (PCR) and reverse-transcription PCR. NheA toxin production was compared based on the absorbance at 414 nm using a Tecra BDE-VIA kit. The NheA-specific production (absorbance/viable cell number) values indicated that the two B. thuringiensis var. kurstaki isolates from microbial pesticide produced the highest amount of toxin (0.66–0.95) than other B. thuringiensis (0.14–0.45) and the B. cereus strains (0.19–0.31). However, the B. thuringiensis strains had longer doubling time (20–26 min) than the B. cereus strains (18–19 min). Interestingly, two B. thuringiensis var. kurstaki isolates produced the highest amount of NheA toxin, and their doubling times (20–22 min) were close to those of the B. cereus strains tested.
최혜준,신수진,김성란,김승지 한국성인간호학회 2023 성인간호학회지 Vol.35 No.4
Purpose: The purpose of this study was to investigate the moderating role of positive psychological capital on the effects of clinical nurses' responses to violence on burnout and to provide basic date for an intervention program that reduces nurse burnout. Methods: The participants in this study were 172 nurses recruited through convenience sampling at one general hospital in Seoul. Data were collected from June 5 to 10, 2023 using structured questionnaires. The collected data were analyzed using SPSS/WIN 26.0. Results: Burnout was positively correlated with violence responses and negatively correlated with positive psychological capital among clinical nurses. Verbal violence experience (β=.14, p=.014), job satisfaction (β=.31, p<.001), social violence response (β=.15, p=.035) and positive psychological capital (β=-.39, p<.001) were identified as factors significantly influencing clinical nurses' burnout. The interaction term between social violence response and positive psychological capital significantly influenced burnout (β=.18, p=.044). Conclusion: Social violence response affected burnout among clinical nurses, and positive psychological capital was identified as a moderating factor in burnout. Therefore, hospital and nursing organizational efforts such as fostering an appropriate organizational atmosphere, providing social support that encourages trust and creativity among organizational members, and implementing various educational and mentoring programs are required to reduce nurses' social violence response and enhance positive psychological capital.
COPD환자에게 적용한 가상현실기반 운동 중재의 효과: 체계적 문헌고찰
최혜준 ( Haejun Choi ),차민주 ( Minjoo Cha ) 이화간호과학연구소 2023 Health & Nursing Vol.35 No.1
Purpose: The purpose of this study is to investigate the efficacy of virtual reality-based exercise interventions for COPD (chronic obstructive pulmonary disease) patients through a systematic analysis of randomized controlled trials published internationally. This approach aims to validate the effectiveness of virtual reality exercise interventions. Methods: Based on databases such as PubMed and RISS, search terms included ‘chronic obstructive pulmonary disease’, 'COPD', ‘virtual reality’, ‘virtual reality rehabilitation’ and ‘videogame’ between 2012 and 2022. Four published articles from 20 screened articles met the inclusion criteria. Results: The study found that virtual reality-based exercise interventions for COPD patients effectively improve exercise function. The interventions had a positive impact on various aspects of physical fitness, such as aerobic capacity (6WMT, 6-minuite walk test), upper and lower body flexibility, agility and balance, upper body strength, lower body strength and back stretch. Conclusion: While this study has demonstrated the effectiveness of virtual reality-based exercise interventions for improving exercise function in COPD patients, the protocols for each study were inconsistent. Therefore, additional research with consistent application of exercise intervention time and frequency is needed to develop a consistent and appropriate program that can be used as an intervention to enhance self-care capacity in COPD patients.
노경규,최혜준,박수영 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Scalable water-dispersible carbon materials(single wall nanotube film, graphene powder) were prepared with consecutive chlorosulfonic acid (CSA)/H2O2 and methylmorpholine N-oxide monohydrate (NMMOm) treatments, followed by the common filtering, sonication, and drying processes. The produced carbon materials film had an almost defectfree structure and good redispersibility in water. Electrical conductivity of carbon materials are 381.5 S/cm(SWNT) and 86.9 S/cm(graphene) from the filtered film. The spin-coated thin film from the aqueous carbon materials solution exhibited a single-layered, single-fiber structure, which was examined using scanning electron microscopy and atomic force microscopy(with selective area electron diffraction). The aqueous carbon materials solution was utilized as the reaction medium for the in situ emulsion polymerization of acrylic paste to produce the conductive adhesive nanocomposite.
최고은,이경은,양지은,안수빈,김영우,최슬기,최혜준,김나현,간보선 이화여자대학교 간호과학대학 2015 이화간호학회지 Vol.- No.49
Objectives : The purpose of this research is to analyze the frequency, clinical characteristics of premenstrual syndrome, and the relationship between premenstrual syndrome and depression in middle school girls. Methods : Subjects of the research were 241 students recruited from 3 women's middle schools in Seoul, Korea. The questionnaires were composed of clinical characteristics of menstruation, Premenstrual Symptom Screening Tool, and Center for Epic Studies Depression Scale. Data were statistically analyzed by Chi-square, t-test, ANOVA, and Scheffe test. Results : The proportion of no/mild premenstrual syndrome was 83.4%, moderate to severe premenstrual syndrome was 12.9% and premenstrual dysphoric disorder was 3.7%. Premenstrual syndrome proportion was higher in severe menstruation pain group(χ2=11.956, p=.008) and depression group (χ2=50.85, p<.001). The mean of depression score was 11.61±9.09. Menstrual pain (F=4.59, p=.004) and premenstrual syndrome (F=68.81, p<.001) were found to be significant in depression. Conclusions : We identified that 16.6% of middle school girls suffered from premenstrual syndrome. We also analyzed that the clinical characteristics of menstruation pain and depression were related to premenstrual syndrome. And there was a relationship between depression and premenstrual syndrome. Accordingly, we can think of applying nursing interventions on menstruation pain and depression in middle school girls who are undergoing premenstrual syndrome.