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원추각막에서 각막내 링(KeraRing#174;) 삽입술의 임상성적
최성욱,최우석,허준,Sung Wook Choi,MD,Woo Seok Choae,MD,Jun Her,MD 대한안과학회 2011 대한안과학회지 Vol.52 No.3
Purpose: To report the outcomes after the implantation of intrastromal corneal ring segments (KeraRing<sup>®) by manual tunnel creation for the correction of keratoconus. Methods: The present retrospective case series was comprised of 12 eyes of 11 consecutive keratoconic patients. Intrastromal corneal ring segments (KeraRing<sup>®) were implanted for keratoconus correction after manual tunnel creation. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refractive outcome, and complete ophthalmologic examinations were performed before and after surgery at 1 day, 1 week, 3 months, and 6 months. Corneal topography was measured before surgery, 6 months after surgery and during any necessary follow-up visits. Results: Intrastromal corneal ring segments (KeraRing<sup>®) implantation significantly increased BCVA from logMAR 0.47 ± 0.19 to logMAR 0.28 ± 0.17 (p < 0.05) and decreased the spherical equivalent from -6.03 ± 3.24 D to -2.24 ± 1.96 D. The simulated keratometric value in the Orbscan IIz significantly decreased in K maximum from 50.7 ± 2.93D to 47.65 ± 3.15 D and in K minimum from 47.65 ± 3.15 D to 44.92 ± 2.80 D. Conclusions: Intrastromal corneal ring segments implantation (KeraRing<sup>®) by manual tunnel creation appears to be effective in improving BCVA and reducing corneal astigmatism and keratometric value in keratoconic patients. KeraRing<sup>® may delay or prevent the need for a corneal graft, and reduce the contact lens intolerance. J Korean Ophthalmol Soc 2011;52(3):277-284
비성기부 지루각화증에서 HPV DNA Chip을 이용한 Human Papillomavirus DNA 검색
이운하 ( Un Ha Lee ),최우석 ( Woo Seok Choi ),김성우 ( Sung Woo Kim ),박현수 ( Hyun Su Park ),장상재 ( Sang Jai Jang ),황선욱 ( Seon Wook Hwang ),이혜경 ( Hye Kyung Lee ) 대한피부과학회 2008 大韓皮膚科學會誌 Vol.46 No.10
Background: The precise etiology of seborrheic keratosis (SK) is unknown. Genetics, sun exposure and infection have all been implicated as possible factors. Because of its clinical and histopathological similarities to verrucae vulgaris and condyloma acuminatum, human papillomavirus (HPV) has been suggested as a possible causative agent. In the previous studies, HPV were frequently detected in the genital lesions or hair follicles of immunocompromised hosts. Objective: A newly introduced HPV detection technique, the HPV DNA Chip analysis, contains 24 HPV probes and it has the advantage of being able to detect 24 types of HPV at once. The purpose of this study was to evaluate the presence of HPV DNA in the nongenital SK of immunocompetant individuals. Methods: We analyzed 31 biopsy specimens that were taken from patients with nongenital SK, and these specimens were compared with genital warts (the positive control) and distilled water in place of DNA (the negative control) with using HPV DNA Chip analysis and a polymerase chain reaction-based DNA microarray system as the HPV genotyping method. Results: By polymerase chain reaction (PCR), HPV DNA was detected in 2 of the 31 nongenital SK biopsies (6.5%). HPV DNA Chip analysis revealed that 3 of 31 nongenital SKs (9.7%) contained HPV DNA. Two distinct HPV genotypes were detected: HPV type 16 (n=2) and HPV type 42 (n=1). The duration of SK in the HPV positive group was longer than that of the SK in the negative group. The mean age of the patients in the HPV positive group was also older than the mean age of the negative group. There were no different histopathologic findings between the HPV positive and negative SK. Conclusion: This study did not provide any concrete evidence that HPV infection might directly play a part in the pathogenesis of nongenital SK. However, two distinct HPV DNA types were identified as types that have never been reported before. Further studies with a larger number of cases of SK are needed to confirm the presence of HPV DNA in nongenital SK and also to determine the role of HPV in the origin of nongenital SK. (Korean J Dermatol 2008;46(10):1321∼1327)
하윤석(Yun-Sok Ha),김광택(Kwang Taek Kim),남욱(Wook Nam),박홍주(Hongzoo Park),유상준(Sangjun Yoo),이찬호(Chan Ho Lee),정호석(Ho Seok Chung),최우석(Woo Suk Choi),김지연(Jiyoun Kim),신재은(Jaeeun Shin),김정현(Jeong Hyun Kim),곽철(Cheol 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.3
Purpose: The survey was conducted on Korean men to examine information acquisition channel for prostate cancer high risk group as part of the “Blue Ribbon Campaign” of the Korean Urological Oncology Society. Materials and Methods: An online survey of 500 men aged 50 years old or older was completed to query investigation of the status of prostate cancer awareness and information acquisition from February 4 to February 9, 2021. Results: Most men in their 50s and older are well aware that prostate cancer can also occur in young men in their 40s, so the rate of misunderstanding of the timing of prostate cancer screening after their 60s is very low. Two-thirds of all respondents (67.2%) were also confirmed that prostate cancer had no initial symptoms and was not included in the national cancer screening. Seventy-five percent of people look up information on their own in case of suspected prostate cancer, and 51.6% seek out knowledge on their own to prevent prostate cancer. Of the respondents, 27.4% of men contacted prostate cancer-related information within the past year, and the percentage of people contacted through ‘Internet/Phone,’ ‘People Around’ and ‘Television’ was high. The most trusted channel among prostate cancer information channels was ‘medical professionals,’ but the experience rate was not high, and the channel with high experience rate and reliability was shown as ‘television.’ Conclusions: Much effort is still needed to understand the information acquisition behavior of Korean men and to improve awareness of early screening for prostate cancer.