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사람 섬유아세포에서 세리신잠 실샘가수분해물(Sericinjam Gland Hydrolysate)의 항산화 및 항노화 효과
천유리 ( Yuri Cheon ),황정욱 ( Jung Wook Hwang ),이희삼 ( Heui Sam Lee ),윤세영 ( Seiyoung Yun ),최용수 ( Yong-soo Choi ),강상진 ( Sangjin Kang ) 대한화장품학회 2013 대한화장품학회지 Vol.39 No.1
본 논문에서는 세리신잠 실샘 가수분해물(Sericinjam Gland Hydrolysate: SJGH)을 이용하여 진피 섬유아세포에서 항산화 및 항노화 연구를 진행하였다. SJGH는 사람 섬유아세포에서 고농도의 과산화수소에 의한 세포사멸과 세포 내 산화 증가를 효과적으로 방어하였다. 또한 SJGH는 저농도의 과산화수소에 의한 섬유아세포의 SA-β-Gal 발현과 MMP-1의 발현 증가를 억제하였고, 반대로 프로콜라겐 I의 생합성은 증가시켰다. 이러한 결과를 통해 SJGH의 항산화 및 항노화 효과가 우수함을 확인하였으며, SJGH가 항노화 화장품의 우수한 소재가 될 수 있음을 보여준다. We studied the anti-oxidant and anti-aging activities of Sericinjam Gland Hydrolysate (SJGH) in the human dermal fibroblasts. SJGH effectively defended cell death and ROS generation under high H<sub>2</sub>O<sub>2</sub> in human dermal fibroblasts. Moreover SJGH reduced the expression of SA-β-Gal and MMP-1 under low concentration of H<sub>2</sub>O<sub>2</sub> whereas biosynthesis of procollagen-Ⅰ was increased. This results demonstrate the anti-oxidant and anti-aging activities of SJGH. SJGH could be a good candidate for anti-aging cosmetics ingredient.
유기농 감자재배지에서 감자역병에 의한 병 진전 및 수량감소
류경열,천정욱,지형진,최두회,김병섭,김종태 한국식물병리학회 2005 식물병연구 Vol.11 No.2
Late blight of potato caused by Phytophthora infestans is one of the most destructive disease in organic farming as well as in the conventional cultivation in Korea. Incidence and progress of the disease largely depend on climatic conditions around the fields. However, the disease completely destroys whole leaves of the plant within two weeks in organic farming fields. While, potato leaves in conventional farming fields remain healthy for 5 weeks after the first symptom appearance, because fungicides were applied four times in average to control the disease. Area under disease progress curve (AUDPC) of organic farming fields ranged from 2314 to 2421 and quickly expanded compare to that of conventional farming fields. The tuber yield in the organic farming fields ranged from 0.96 ton per 10a to 1.5 ton per 10a, while it was 2.7 ton per 10a in conventional farming fields. Tuber yields were reduced to 42~63% by the infection of late blight and the reduction rate was closely related with the time of first occurrence of the disease in organic farming fields. Physiological races of the pathogen were diversified with R0,1,3,4,5,7,10,11 in organic farming fields at Hongchun area. Pathogen races were distributed with similar pattern at different areas of organic farming fields.
류경열,박영은,천정욱,김숭열 한국육종학회 2006 한국육종학회지 Vol.38 No.5
This work was carried out to evaluate the resistance of potato germplasm against late blight in Korea. Seven races ofPhytophthora infestans were detected from the main potato growing areas. Three races of pathogen were isolated from mono-crop-ping areas a
Virulence Differentiation of Eight Turnip mosaic virus Isolates Infecting Cruciferous Crops
최홍수,윤무경,최장경,김국형,천정욱,Seong-Han Sohn,Jeong-Soo Kim,Hassan Karakacha Were,Yoichi Takanami 한국식물병리학회 2005 Plant Pathology Journal Vol.21 No.4
Turnip mosaic virus (TuMV) is an infectious viral pathogen on the cruciferous crops, predominantly Chinese cabbage (Brassica campestris subsp. pekinensis) and radish (Raphanus sativus). On the basis of the symptom development in selective differential hosts from indicator host species, Chinese cabbage and Korean radish inbred lines, the representative eight isolates of TuMV were divided into two major groups/or six types. Group I includes Tu 1, Ca-ad7, and Cj-ca2-1 isolates, while group II includes the other isolates (rg-pf1, r 9-10, Rhcq1- 2, Stock and Mustard). According to the molecular phylogenetic analysis, these isolates, however, divided into two groups and two independent isolates. Phylogenetic analysis indicated that four isolates (Tu 1, r 9-0,Stock and Rh-cq1-2) formed a distinct phylogenetic group, and the other two isolates (Ca-ad7 and Cj-ca2-1) also formed another group. Mustard and rg-pf1 isolates did not seem to have any relationship with these two groups. Taken together, these results indicated that virulence differentiation on host plants, molecular phylogenetic analysis of the nucleotide and the deduced amino acid of TuMV coat proteins did not show any relationship. The multi-resistant lines, Wonyae 20026 and BP058 in Chinese cabbage represent valuable genetic materials that can be used for crucifer breeding programs on TuMV resistance, but not in Korean radish.
행정구역 통합, 어떤 전략이 필요한가?:청주시-청원군 행정구역 통합사례를 중심으로
이태천,이정욱 한국지방정부학회 2023 지방정부연구 Vol.27 No.2
The consolidation of administrative districts has been attempted in various regions for a long time with the expectation of stimulating regional economies and overcoming administrative inefficiencies. However, due to the complexity of relationships and acute conflicts between stakeholders, it remains a challenging task, akin to a “wicked problem”. In this context, the 2012 case of Cheongju-Cheongwon consolidation stands out as an exceptional example, and analyzing this case holds significant implications for discussions on successful consolidation. According to Matland's (1995) “contingency approach” to policy implementation, the successful execution of a policy depends on selecting implementation strategies that align with the policy's characteristics and effectively taking action. Administrative districts consolidation has clear policy goals, but conflicts among stakeholders due to divergent interests create significant hurdles. As a result, it becomes crucial to secure substantial authority and political resources to foster an environment conducive to effective negotiation and achieving consensus— a critical aspect of the political implementation strategy. This study utilizes Moore's (1995) “political management” framework, which proves valuable for evaluating effectiveness and choosing political implementation strategies. It analyzes the four periods that led to the successful Cheongju-Cheongwon consolidation and derives a series of strategic implications related to administrative districts consolidation.
이기창,류정욱,황성규,황용현,성기천 한국유화학회 1991 한국응용과학기술학회지 Vol.8 No.2
The kinetics of the addition of 1-benzylindole-3-(p-substituted) acetophenone derivatives was investigated by ultraviolet spectrophotometery in 30% dioxane -H_2O at 25℃. A rate equation which can be applied over wide pH range was obtained. The Substituent effects on 1-benzylindole-3-(p-substituted) acetophenone derivatives were studied, and addition were facilitated by electron attracting groups. On the base of the rate equation, substituent effect, and general base effect the plausible addition mechanism was proposed : Below pH 0.0~14.0, natural thiourea molecule and thiourea anion competitively attacted the double bond. By contrast, above pH 10.0, the reaction was dependent upon only the addition of thiourea anion.