가정 내 부유 진균의 농도와 관련 요인

조용민,류승훈,최민석,서성철,정지태,최재욱,Cho, YongMin,Ryu, SeungHun,Choi, Min Seok,Seo, SungChul,Choung, Ji Tae,Choi, Jae Wook 한국환경보건학회 2013 한국환경보건학회지 Vol.39 No.5

Objectives: This study was performed in order to determine airborne fungi levels in homes and find related factors that may affect airborne fungi concentration. Methods: Fifty homes were study subjects for measuring airborne fungi. For sampling airborne fungi, the impaction method on agar plates was used and samples were counted as colony forming units per cubic meter of air ($CFU/m^3$). In addition, information regarding housing characteristics and atopic disease in each home were collected via questionnaire. Results: The geometric means (GM) of airborne fungi concentrations in fifty living rooms and bedrooms were 68.03 and 62.93 $CFU/m^3$, respectively. The GM of airborne fungi concentration in atopy homes was 78.42 $CFU/m^3$. This was higher than non-atopy homes' 54.34 $CFU/m^3$ (p-value=0.051). In the results of the multiple regression analysis, outdoor airborne fungal concentration proved a strong effective factor on indoor airborne fungal concentration. Also, construction year, floor area of house, indoor smoking and frequency of ventilation were factors that showed a significant association with indoor airborne fungi concentration. Conclusions: The results of this study show that some housing and living characteristics may affect the development and increase of airborne fungi. In addition, exposure to airborne fungi may be a risk factor for the prevalence of childhood atopic diseases.

과학기술분야 공공연구개발인력의 프로티언 경력태도가 무형식 학습 활동을 매개로 혁신적 업무행동에 미치는 영향

조용민(Yongmin Cho),변호승(Hoseung Byun) 한국기업교육학회 2023 기업교육과인재연구 Vol.25 No.3

지방자치단체 중심의 아토피 예방관리 프로그램 효과 평가

서성철,조용민,류승훈,이승길,이지연,정지태,Seo, SungChul,Cho, YongMin,Ryu, SeungHun,Lee, Seung Kil,Lee, Ji Yeon,Choung, Ji Tae 한국환경보건학회 2013 한국환경보건학회지 Vol.39 No.4

Objectives: We evaluated the effects of an allergy control program on children with atopic dermatitis (AD) in five schools located within Gyeonggi-do. Methods: Based on the results of the 12-month prevalence of AD symptoms from an International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire of all students (n=2109; 1040 boys, 1069 girls) at five randomly selected schools, 227 students with AD symptoms were screened. Finally, 188 students with greater than 1 on SCORAD (SCORing Atopic Dermatitis) determined by a physician were selected. The allergy control program includes education related to allergic diseases, skin prick tests, and SCORAD evaluation, as well as keeping a daily journal to check the usage of moisturizer at least once a day. To determine the effectiveness of the allergy control program, SCORAD evaluation was performed again six weeks later. Results: The most common symptom for 12-month prevalence was rhinorrhea (33.9%), followed by atopic skin lesions (14.8%) and wheezing (4.0%). The 12-month prevalences of the three allergic diseases were higher for boys than for girls, and a significant difference was found for allergic rhinitis (P<0.001). The mean SCORAD index decreased significantly from 26.1 to 17.5 after the completion of the six-week control program (P<0.01). In particular, these differences were more pronounced for the group which used the daily journal (P<0.001). Conclusions: Our findings indicate that the allergy control program including usage of a daily journal as well as regular monitoring could be a promising tool for preventing and alleviating the symptoms of allergic diseases.

FI-HG-AAS를 이용한 전처리 과정에서 사용되는 예비환원제의 종류에 따른 요중 비소 분석결과 비교

최승현,최재욱,조용민,배문주,Choi, Seung-Hyun,Choi, Jae Wook,Cho, YongMin,Bae, Munjoo 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.5

Objectives: The method of analyzing urinary arsenic by flow injection hydride generation atomic absorption spectrometry (FI-HG-AAS) is generally used because it shows relatively greater sensitivity, low detection limits, low blocking action, and is simple to operate. In this study, the results of analysis according to three pre-reductants commonly used in the FI-HG-AAS method were compared with each other. Methods: To analyze urinary arsenic, nineteen urine samples were collected from adults aged 43-79 years old without occupational arsenic exposure. Analysis equipment was FI-HG-AAS (AAnalyst 800/FIAS 400, Perkin- Elmer Inc., USA). The three pre-reductants were potassium iodide (KI/AA), C3H7NO2S (L-cysteine), and a mixture of KI/AA and L-cysteine (KI/AA&L-cysteine). Results: In the results of the analysis, the recovery rate of the method using KI/AA was 82.3%, 95.7% for Lcysteine, and 123.5% for KI/AA and L-cysteine combined. When compared with the results by use of high performance liquid chromatography inductively-coupled plasma mass spectrometry (HPLC-ICP-MS), the method using L-cysteine was the closest to those using HPLC-ICP-MS ($98.57{\mu}g/L$ for HPLC-ICP-MS; $74.96{\mu}g/L$ for L-cysteine; $69.23{\mu}g/L$ for KI/AA and L-cysteine; $13.06{\mu}g/L$ for KI/AA) and were significantly correlated (R2=0.882). In addition, they showed the lowest coefficient of variation in the results between two laboratories that applied the same method. Conclusion: The efficiency of hydride generation is considered highly important to the analysis of urinary arsenic via FI-HG-AAS. This study suggests that using L-cysteine as a pre-reductant may be suitable and the most rational among the FI-Hg-AAS methods using pre-reductants.

실질적 동등성에 근거한 유전자변형 벼의 안전성 평가

조영규(Youngkyu Cho),이정호(Jeongho Lee),윤태현(Taehyun Yun),조용민(Yongmin Jo),오선우(Seonwoo Oh),주용성(Yongsung Joo) 한국자료분석학회 2023 Journal of the Korean Data Analysis Society Vol.25 No.6

유전자변형작물은 기존 작물과 비교하여 비의도적 변화 여부 및 실질적 동등성을 확인하기 위해 상업적 이용 전에 안전성 평가 심사 승인을 받아야 한다. ‘실질적 동등성’에 기반한 안전성 평가는 GM 작물과 비교작물을 비교하는 단계적 접근 방법으로 수행하는데, 이는 평가하고자 하는 항목에서 비교작물 간에 통계적 차이 혹은 자연변이 범위 내에서의 동등성을 확인하여 판단한다. 예를 들어 안전성 평가항목에서 GM 작물과 대조작물 간에 통계적 유의한 차이가 있는 것으로 확인되면 시중에 유통되고 있는 상업화 품종과 비교해서 이들 성분의 함량 범위 내에 포함되는지를 추가적으로 분석하여 자연변이 접근법으로 동등성을 판단하고 결론한다. 추가 분석에서도 GM 작물의 특이성이 발견된 경우, 생물학적 또는 독성학적 분석이 진행된다. 본 논문에서는 현재 GM 작물의 실질적 동등성 평가에서 사용되고 있는 다양한 통계 방법들을 비교 정리하였다. 실질적 동등성 평가를 위한 통계기법 연구를 위해 해충저항성 유전자변형 벼와 비교작물의 성분분석 자료, 농촌진흥청 작물성분 DB 자료를 이용한 분석을 진행하였다. GM 작물의 실질적 동등성 평가는 영양성분을 비롯하여 독성, 알레르기성, 영양성 등의 평가항목에서 수행된다. 본 연구에서는 벼의 안전성 평가항목 데이터로 통계분석을 수행하였으며, 분석 결과와 이론적 내용을 통합하여 실질적 동등성 평가방법의 개선점을 발굴하고 합리적인 통계분석 방법을 제시하였다. Genetically modified crops must undergo safety evaluation approval before commercial use, ensuring substantial equivalence compared to conventional crops. Safety assessment based on 'substantial equivalence' involves a stepwise approach, comparing GM crops with their non-GM counterparts, examining statistical differences or equivalence within the natural variability range for the desired attributes. For instance, if statistically significant differences are observed in safety test items between GM and control crops, additional analysis compares them to the commercially available varieties to determine inclusion within their compositional range. Further analysis involves biological or toxicological assessments if difference between GM crops and others are identified. Using data from insect-resistant genetically modified rice and its non-GM counterpart, available in the Rural Development Administration's crop component database, we applied statistical methods for substantial equivalence assessment. The substantial equivalence assessment of GM crops covers various evaluation aspects, including toxicological, allergenic, and nutritional attributes. In this study, statistical analysis was performed on rice's nutritional component data, integrating the results with theoretical contents.

레이저프린터에서 배출되는 공기 중 오염물질 조사

서성철(SungChul Seo),조용민(YongMin Cho),김미나(Mina Kim),이승길(Seungil Lee),김해준(HaeJoon Kim),이동현(Donghyun Lee),최재욱(Jae-Wook Choi) 한국실내환경학회 2011 한국실내환경학회지 Vol.8 No.4

The aim of this study was to compare the concentrations of airborne pollutants (i.e., PMs, TVOC, and ozone) released from a laser printer with a new and/or a refilled toner cartridge. Also we compared the concentrations before and after attaching a HEPA filter at the outlet of exhausted air for each printer. PMs, TVOC, and ozone were released from all three different branded printers with both toner cartridges in accordance with their both a brand new and a used condition. For PMs, there were generally significant differences of concentrations between a brand new and used toner (p<0.05). Ozone level differences were found between a new and a refilled toner, but were not significant (p>0.05). For TVOC, there were significant differences of concentrations among brands, and toluene (3.46 ㎎/㎥) only was identified. The overall 70% of reduction for PMs' concentrations occurred after attaching a HEPA filter(p<0.05), and these results were pronounced for TSP. These results showed that similar levels of airborne pollutants were released from a laser printer with a new and a refilled toner cartridge. Also, these results indicate that the usage of a HEPA filter may be an effective method for reducing the released pollutants from a laser printer.

유압 구동시스템용 체크 밸브의 유동특성 및 구조안정성에 관한 연구

우위팅(Yu-Ting Wu),진진(Zhen Qin),곽기명(Gimyeong Gwak),류성기(Sungki Lyu),조용민(Yongmin Cho),백승호(Seoungho Back),박상후(Sanghu Park) 대한기계학회 2021 大韓機械學會論文集A Vol.45 No.7

유압 구동시스템은 여러 산업기계에서 널리 사용되며 체크 밸브는 유압 동력전달시스템의 중요한 부품이다. 하지만 유로와 하우징의 부적절한 설계로 인하여 고압의 오일이 전달될 때 체크 밸브의 누유 및 손상과 같은 문제가 빈번하게 나타난다. 이러한 문제를 해결하기 위하여 본 연구에서는 유한체적법(FVM)과 유체 동역학 기반의 수치적 연구 수단을 활용하여 유압 기계에 사용하는 “L”자형 고압 체크밸브를 바탕으로 설계를 평가하였다. 또한 유한요소법(FEM)을 바탕으로 내부 고압을 고려하여 체크 밸브 하우징의 구조적 안정성에 대해 시뮬레이션을 진행하였다. 본 논문에서 사용한 연구방법은 다양한 유압시스템용 체크 밸브에 적용이 가능하며 유압 동력전달 과정의 안전성을 보장하기 위하여 중요한 설계 평가 사례를 보였다. Hydraulic drive systems are widely used in the equipment used in various industries, such as agriculture and construction. The internal check valve is an important part of the hydraulic power transmission system in a hydraulic machinery. Because of improper design of the flow circuit and housing, check valves are exposed to various problems, such as leakage and damage, frequently during high pressure transmission. To solve this problem, the L-shaped high-pressure check valve used in hydraulic machinery was designed and evaluated using the finite volume method and numerical research method based on fluid dynamics. Furthermore, considering the impact of high internal pressure on the check valve shell, the structural stability of the valve was simulated using the finite element method. The research method adopted in this study can be applied to check valves in various hydraulic systems. Additionally, an important design and evaluation example is provided to ensure the safety of the hydraulic power transmission process.

한우의 말초혈액 단핵세포 염증성 사이토카인에 대한 브로피리민의 효과 확인

김승창 ( Seungchang Kim ),이승환 ( Seung-Hwan Lee ),채한화 ( Han-Ha Chai ),김의형 ( Ui-Hyung Kim ),정기용 ( Ki-Yong Chung ),임다정 ( Dajeong Lim ),박종은 ( Jong-Eun Park ),조용민 ( Yongmin Cho ),최봉환 ( Bong-Hwan Choi ) 한국축산학회(구 한국동물자원과학회) 2017 동물자원연구 Vol.28 No.4

Bropirimine, a class of antineoplastic agents, is known as one of the potent immunomodulators and is currently under clinical development for the treatment of cancer. However, the effect of bropirimine on the cow remains unknown as a therapeutics agent. In this experiment, the effect of bropirimine in the peripheral blood mononuclear cells (PBMCs) stimulated by lipopolysaccharide (LPS) or concanavalin-A (Con-A) was examined. Jugular venous blood was collected from Korean Hanwoo calves and PBMCs were isolated. It was used to study the effect of bropirimine upon stimulation with LPS or Con-A for 72 hours. The expression pro-inflammatory cytokines like Tumor Necrosis Factor α (TNF-α) and Interferon γ (IFN-γ) were confirmed. Bropirimine significantly inhibited LPS- or Con-A-induced TNF-α and Con-A-induced IFN-γ in dose-dependent manner. Furthermore, Bropirimine inhibited TNF-α and Con-A mRNA expression at the transcription level. These results clearly indicated that bropirimine inhibited LPS or Con-A stimulated up-regulation of proinflammatory cytokines in a dose-dependent manner without conspicuous cytotoxicity. The bropirimine has potential to protect cow from LPS or Con-A induced endotoxin shock, possibly through inhibition of the production of proinflammatory cytokines. It suggesting that bropirimine may be a novel therapeutic agent for the prevention of inflammatory diseases. This result revealed specific features of the immune responses depending on the bropirimine compound and would help to knowledge of bovine immunity.

골판지포장 공정진단을 통한 내압강도 개선에 관한 연구

조용민,송주완,김진무 한국공업화학회 2003 응용화학 Vol.7 No.2

In this paper, with the diagnosis of progress, we studied the effect of adhesive amounts and warp conditions for improvement of the compression strength in corrugated packaging case. The result of the study on compression strength according to functional speed and adhesive amounts by adjustment of applicator roll and doctor roll gap in gluer shown the effect that compression strength increased about 2.2% and adhesive strength increased about 1.6% when gap was adjusted to 0.2 which is used to 0.17 in production of double wall corrugated fiberboard container. And study in compression strength by the conditions of warp in corrugated fiberboard shown that downer warp condition was higher than upper warp condition. In the linerboards. it is possible assuming that lower basis weight corrugated midium(S base sheet) is weaker in compression strength by warp but this is because of the difference of shape condition between wire-side and felt-side.

Microflute 골판지 제조시 골판지원지 특성분석 및 평가

조용민,송주완,김진무 한국공업화학회 2003 응용화학 Vol.7 No.2

This study carried out the property of linerboards and defining the condition of production by describe the effect of temperature, moisture and rentention time in corrugator for making the MICROFLUTE(M/F) corrugated board with linerboards which is commercial in national and international market. The most efficient condition was 160℃ of temperature, 30% of moisture content in linerboards and 60 second of retention time and draw factor of linerboards increased with increasing of draw factor of the most efficient microflute(F-flute) condition and temperature. Also draw factor of linderboards was more excellent in lower basis weight of linerboard and draw factor of commercial kraft) board(78-98g/㎡) was better than nationally commercial linerboards(S 120g/㎡), B 150g/㎡). In M/F corrugating, the best result of length, thickness, basis weight and draw factor was gained in CD direction of kraft paper with 75g/㎡ of basis weight with having regard to wire/felt-side, MD/CD directions. basis weight of commercial kraft.