치밀형 유방에서 유방특이감마영상검사의 유용성 평가

정은미,김호성,Jeong, Eun-Mi,Kim, Ho-Seong 대한핵의학기술학회 2012 핵의학 기술 Vol.16 No.1

Purpose: This study was to evaluate usefulness of $^{99m}Tc$-MIBI scintimammography for dense breast by comparing concordance in test results between Tc-99m MIBI scintimammography and mammography whose effect was proved the most as an imaging tool depending on breast density and at the same time by examining limitation on evaluation depending on density of breast tissue. [Materials and Methods] In the period from December 2010 to July 2011, this study targeted 150 patients who took both of $^{99m}Tc$-MIBI scintimammography and mammography conducted by using breast gamma camera in this hospital. Breast density was classified to the four levels of pattern 1~4 based on the results of mammography. $^{99m}Tc$-MIBI scintimammography was conducted with the LCC, the RCC, the LMLO, and the RML one minute after intravenous injection of 99mTc-MIBI 7400 MBq (20 mCi) while analysis was made for concordance in test results of $^{99m}Tc$-MIBI scintimammography and mammography. [Results] Among the 150 patients, pattern 1 was found in 3 patients, pattern 2 in 44 patients, pattern 3 in 61 patients, and pattern 4 in 37 patients. There were 5 patients who showed the case where it was impossible to determine density of breast tissue due to foreign body inserted to breast. The concordance ratio of the results between $^{99m}Tc$-MIBI scintimammography and mammography was 95.5% for pattern 2, 95.1% for pattern 3 and 94.6% for pattern 4. This demonstrated that the concordance rate decreased according to the increase in breast density. [Conclusion] When there was limitation on evaluation of breast specific gamma imaging test results due to increased intake in breast tissue or surgical site, the concordance rate was 6.8% for pattern 2, 16.3% for pattern 3 and 18.9% for pattern 4. This demonstrated that the degree of limitation on evaluation of breast specific gamma imaging test results increased according to the increase in breast density.

B형 만성 간염 환자에서 인터페론 단독 요법과 인터페론과 라미부딘 병합 요법의 비교

정은미,홍창권,오성욱,박재완,이준성,김경철,김배영,홍성표,박필원,임규성,김세현,황성규,Jeong, Eun-Mi,Hong, Chang-Kwon,Oh, Seong-Wook,Park, Jae-Wan,Lee, June-Sung,Kim, Kyung-Chul,Kim, Bai-Young,Hong, Sung-Pyo,Park, Pil-Won,Rim, Kyu-Sung,Kim 대한임상약리학회 2000 臨床藥理學會誌 Vol.8 No.1

Background/Aims: Hepatitis B virus (HBV) is associated with clinically significant chronic infection that may lead to the development of cirrhosis or even hepatocellular carcinoma. However, interferon alpha is effective in only 25-40% of chronic hepatitis B patients. The purpose of this study was to evaluate the effectiveness of interferon and lamivudine combination treatment comparing with interferon alone. Methods : Twenty patients with chronic hepatitis B(moderate to severe activity) were randomized to with interferon alone (11 patients) or combination (9 patients) therapy for 24 weeks. The patients were monthly evaluated, biochemically and serologically. Results : There was no statistical difference between both groups in HBeAg seroconversion rate and ALT normalizaion rate at the end of treatment. But, HBV DNA suppression rate was significantly higher in combination group (100%) than the interferon alone group (54%). No serious side effects were noted in both groups. Conclusion : Combinaton therapy with alpha interferon plus lamivudine given for 24 weeks appears safe and is well tolerated. But, combination therapy was no more efficient than interferon alone in HBeAg seroconversion except HBV DNA suppression rate during the treatment period.

버섯균사체로 배양된 인삼 Saponin과 β-Glucan 함량 변화

정은미,황인국,이현용,정재현,유광원,정헌상,Joung, Eun-Mi,Hwang, In-Guk,Lee, Hyeon-Yong,Jeong, Jae-Hyun,Yu, Kwang-Won,Jeong, Heon-Sang 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.8

인삼을 배지로 사용하여 목질진흙버섯(Phellinus linteus), 영지버섯(Ganoderma lucidum) 및 노루궁뎅이버섯(Hericium erinaceum) 균사체를 접종 배양하여 얻어진 균사체 인삼배양물과 원료 인삼에 대한 사포닌과 $\beta$-glucan의 변화를 분석하였다. 원료인삼의 구성사포닌 함량은 22.47mg/g이었으나 균사체로 배양된 인삼의 사포닌 함량은 목질 진흙버섯이 39.78 mg/g, 영지버섯이 55.88 mg/g 그리고 노루궁뎅이버섯이 32.69 mg/g으로 원료인삼에 비해 증가하였다. 균사체 인삼배양물의 사포닌은 PPT계는 감소하였고 PPD계는 증가하였다. 구성사포닌 중 ginsenoside Rd는 원료인삼에 비해 균사체 인삼배양물에서 각각 17, 30 및 12배 증가하였다. 3종의 균사체와 균사체 인삼배양물들의 총 glucan 함량은 각각 46.24, 34.74 및 34.02% 그리고 28.77, 17.78 및 21.77%이었다. $\beta$-glucan 함량은 균사체에서는 각각 29.14, 19.44 및 23.39%이었고 인삼배양물에서는 각각 8.85, 5.46 및 5.51%로 나타나 목질진흙버섯이 균사체와 인삼배양물에서 가장 높은 함량을 나타내었다. This study investigated the changes of saponin and $\beta$-glucan content on the cultured ginseng with mushroom mycelia of Phellinus linteus (PL), Ganoderma lucidum (GL), and Hericium erinaceum (HE). Cultured ginsengs with mushroom mycelia were extracted with 80% ethanol, fractionated with n-buthanol, and analysed for ginsenosides by high performance liquid chromatography (HPLC). Crude saponin content of raw ginseng was 4.11% (d.b) but cultured ginseng with mushroom mycelia of PL, GL, and HE were increased to 6.74, 6.77 and 6.23% (d.b), respectively. Ginsenoside-Rd, among the 12 ginsenosides which were available for analysis, was remarkably increased to 13.61, 24.26, and 32.69 mg/g, respectively (raw ginseng: 0.80 mg/g). The $\beta$-glucan content of cultured ginseng with mushroom mycelia of PL, GL, and HE were decreased to 8.85, 5.51 and 5.46% rather than mushroom mycelia of 29.14, 19.44, and 23.39% (d.b), respectively.

카자흐스탄 언어 정책의 현황과 미래- 삼중언어정책을 중심으로

정은미 ( Eun Mi Jeong ) 한국외국어대학교 중동연구소 2014 중동연구 Vol.33 No.2

This study reviews the language policy in Kazakhstan to understand the current situation of the three main languages: Kazakh as a state language, Russian as a language of interethnic communication and official language, and English as a newly respected main language, and predicts the future of the language policy in Kazakhstan focusing on trilingualism. Since the independence, Kazakh language has been supported to be a state language worthy of its name by the government with the policies such as legislation, education, paper work, qualification for high officials such as president, etc. However, Russian is still influential because of the large number of Kazakhs who prefer to use it in daily life and schools as well as the Russian diaspora living there. In addition, Russian has been considered to be useful for the regional cooperation in Central Asia for the relationship with Russia and other post-Soviet countries. The Kazakhstan government also recommends its nation have English competence to be competitively integrated in the global economy and international relations. Although it could be a slow process, Nazarbayev administration would pursue the ideal goal of the Trinity of languages to develop the nation``s potential for a prosperous future in Kazakhstan. However, it stays uncertain whether the trilingual competence can be realized in the near future. The trilingual model would be implemented and practised successfully, provided that enough time, financial support, motivation, as well as some strong and effective language policy established by the experts related to language policy.

한국의 전통 소반의 조형적 형태를 이용한 문화상품 개발 -공고상의 조형적 특징을 중심으로-

정은미 ( Jeong Eun Mi ) 한국기초조형학회 2016 기초조형학연구 Vol.17 No.6

본 연구는 한국의 전통소반의 하나인 공고상을 응용하여 차와 음료문화와 연관된 문화상품으로 개발하고자 하였다. 연구과정은 차와 음료 문화에 대한 변천을 살펴보고 전통을 응용한 다양한 문화상품 사례를 조사하였다. 그리고 기존의 대중적인 차도구 및 음료 악세서리와 어울리는 문화상품과의 연계성을 파악하였다. 이를 바탕으로 소반 및 공고상의 특징을 연구하여 찻잔받침 및 컵홀더의 기능으로 재해석한 문화상품을 개발하였다. 디자인 전개과정은 우선 소반의 일반적인 특징을 연구하고 이어서 공고상의 기능과 조형적 차별성에 대한 디자인요소를 분석하였다. 다음으로 현재 시중에 유통되는 다양한 제품을 취합하여 디자인의 표본이 되는 사이즈를 규정하고 찻잔받침 및 컵홀더의 본원적 기능에 적합하게 변용하였다. 그리고 투각장식이 조합된 공고상의 조형미를 응용하여 전통찻잔과의 조화를 고려하였다. 공고상의 상판이 수평을 이루고 아래쪽이 넓은 통각형인 구조적 특징을 이용해 뒤집어서 컵을 넣어 고정할 수 있는 컵홀더로도 활용할 수 있도록 했다. 또한 찻잔이나 종이컵 등의 재질이 주는 차가움과 단조로움을 나무의 따뜻한 색감과 결이 어우러져 자연미를 더하도록 했다. 이렇게 디자인된 제품의 양산성을 확보하기 위해 목공기계 및 CAD/CAM을 활용하고 작업공정을 규격화하여 생산성을 향상시킬 수 있는 방법을 마련하고자 했다. 본 연구를 통해 소비자가 전통문화에 대한 가치를 느끼고 실용성과 디자인, 스토리 등이 결합된 찻잔받침 및 컵홀더로 재해석하였다. The purpose of this study is to develop cultural products related with tea and beverage by applying Gonggosang, one of the traditional Sobans in Korea. The procedure of this study is to review the transition of the tea and beverage related culture and to investigate many examples of various cultural products applying the tradition. In addition, the relation of developing cultural products harmonious with the existing popular appliances for tea and the accessories for beverage has been analyzed. On the basis of this, the features of Soban and Gonggosang have been researched and it has been developed as the cultural products reanalyzing the function of the tea and cup holders. In the stage of designing, the general features of Soban have been studied at first, and subsequently the designing factors in the aspect of the function and the formative distinctiveness of Gonggosang have been analyzed. After that, by collecting various products that has been currently being sold, defining the sizes for the design sample has been made and it has been properly transformed to the fundamental function of the teacup and cup holders. In addition, the harmony with the traditional teacups has been considered by applying the formative beauty combined with openwork decoration. Gonggosang has been applied as the cup holder to fix by inserting an overturned cup under by using the structural features that the upper board of Gonggosang is horizontal and the form of the lower part is cylinder and wide. By making the harmonious feeling between the coldness and monotony that the materials of the teacups or paper cups give and the warm colors of the wood, the natural beauty has been added. In order to secure the mass production of such designed products, the wood working machine and CAD/CAM have been used and the methods to improve the productivity have been intended to prepare by standardizing the working process. Through this study, the customers could realize the value of the traditional culture and the Gonggosang has been reanalyzed as the teacup holders or cup holders combined with practicality, design and stories.

저칼륨혈증성 주기성 마비로 발현한 원발성 쇼그렌 증후군

정은미 ( Eun Mi Jeong ),권건호 ( Kun Ho Kwon ),홍창권 ( Chang Kwon Hong ),김형태 ( Hyung Tae Kim ),김경수 ( Kyung Soo Kim ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.2

We describe a 46-year-old woman with hypokalemic paralysis as the initial manifestation of Sjogren`s syndrome. Sjogren`s syndrome is an autoimmune exocrinopathy, characterized by keratoconjuntivitis sicca and xerostomia. Among the extraglandular manifestations of Sjogren`s syndrome, renal tubular involvement, especially renal tubular acidosis, is the most often latent or minimally symptomatic. Renal tubular acidosis is estimated to be present in 25~30 percent of the cases. Hypokalemic paralysis may serve as a clinical marker for more severe renal disease in patient who has primary Sjogren`s syndrome with renal tubular acidosis, even though it is a rare manifestation of Sjogren`s syndrome.

이탈리아 현대 가구디자인의 특성 및 그 배경

정은미(Jeong Eun-Mi) 한국디자인학회 2001 디자인학연구 Vol.- No.40

초등학교 저경력 교사의 정서·행동 문제를 가진 학생 지도경험에 대한 자문화기술지

정은미 ( Jeong Eun-mi ),서유진 ( Seo You-jin ) 한국초등교육학회 2020 초등교육연구 Vol.33 No.4

본 연구는 자문화기술지를 통해 저경력 교사가 부푼 기대와 희망을 품고 교직에 들어섰지만 만만치 않은 교육현장에 부딪치고, 그 속에서 정서·행동 문제를 가진 학생과 학부모를 만나며 경험한 다양한 어려움에 대해 이야기하였다. 연구자의 자기회상, 자기성찰과 자기관찰 자료, 학생, 학부모, 또는 동료교사와의 면담 자료, 학교관련서류와 학생 활동 자료 등과 같은 문화적 인공물들이 연구자료로 수집되고, 내용 분석과 구조 분석을 통해 총 4개의 주제와 9개의 하위주제가 도출되었다. 도출된 4개의 주제는 (1) 아직 준비가 안 된 새내기 교사, (2) 이제, 전쟁의 시작, (3) 점점 소진되어 가는 교사, (4) 그럼에도 불구하고: 다시 힘을 내어 일어나기이다. 본 연구를 통해 도출된 주제를 토대로 저경력 교사의 교직생활 적응과 성장을 위해 필요한 개선점과 지원방향을 논의하였다. As autoethnography this study investigated a variety of difficulties that the short-career elementary teacher encountered when she met students with emotional and behavioral problems and their parents. The study collected the researcher’s self-recall, self-reflection, and self-observation data, interveiw data with students, parents, and fellow teachers, and cultural artifacts, for example, school related documents and students’ activity data. With the content analysis and structural analysis, the study identified 4 themes and 9 sub-themes. The four themes were (1) a short-career teacher without readiness, (2) Now, a beginning of war, (3) a teacher's burning out, and (4) even though: start again. Based on these results, several ways of changes and supports for a short-career teacher were discussed.

이탈리아 가구산업의 성공요인

정은미(Jeong Eun-Mi) 한국디자인학회 2007 디자인학연구 Vol.20 No.5

제도변화의 메커니즘 분석

정은미(Eun Mi Jeong),류석진(Seok Jin Lew) 경기연구원 2017 GRI 연구논총 Vol.19 No.2