한국인 음식물 의존성 운동유발 아나필락시스의 임상적 특성 분석

정수지 ( Soo Jie Chung ),심지수 ( Jisu Shim ),김형준 ( Hyung-jun Kim ),손경희 ( Kyoung-hee Sohn ),강성윤 ( Sung-yoon Kang ),강민규 ( Min-gyu Kang ),박한기 ( Han-ki Park ),강혜련 ( Hye-ryun Kang ) 대한천식알레르기학회(구 대한알레르기학회) 2016 Allergy Asthma & Respiratory Disease Vol.4 No.6

Purpose: Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare subtype of food allergy in which both sensitization to food allergen and exercise as a trigger contribute to its development. However, its pathogenesis is still under investigation. This study compared clinical features, the causative foods, and the degree of sensitization to food between FDEIA and food anaphylaxis to characterize FDEIA more clearly. Methods: We retrospectively reviewed the medical records of patients who were diagnosed with FDEIA (n=89) or food anaphylaxis (n=115) between 2003 and 2015 at Seoul National University Hospital. Results: Subjects with FDEIA more frequently had urticaria than those with food anaphylaxis (88.8% vs. 76.5%, P=0.024). Whereas patients with FDEIA had less laryngeal edema than those with food anaphylaxis (12.4% vs. 30.4%, P=0.02). Wheat (67.4%) was the most common causative food allergen in FDEIA, whereas seafood (40.9%) was the most common culprit food allergen in food anaphylaxis. Also, subjects with FDEIA showed a lower atopic index score than those with food anaphylaxis (0.55±1.07 vs. 1.21±1.82, P=0.006). Conclusion: There were significant differences in clinical manifestation, causative food allergens and the degree of sensitization to food between FDEIA and food anaphylaxis. (Allergy Asthma Respir Dis 2016:4:436-441)

전통누룩을 이용한 ale맥주 제조 및 품질특성

정수지(Suji Jung),정장호(Chang-Ho Chung) 한국식품과학회 2017 한국식품과학회지 Vol.49 No.2

시판 누룩을 맥주의 당화과정에 첨가하여 얻은 맥주의 특성을 확인한 결과, 가용성 고형분 함량은 발효 직후에 급격히 줄어들어 숙성기간과 저장기간 동안 비슷한 수치로 이어졌다. pH는 발효 직후 5.7에서 4.1-4.2까지 낮아졌고, 숙성과 저장 기간을 거치면서 비슷한 수치를 유지하였다. 미생물은 대부분 효모균으로 숙성기간인 6일에 약 5.16×105 CFU/mL에서 13일 2.92×106 CFU/mL로 균수는 증가하였다. 맥주의 색은 SRM 색도와 색차계로 분석한 결과 SRM은 누룩의 첨가량이 많아짐에 따라 발효, 숙성, 저장 기간 내내 높은 수치를 보였다. 색차계에서는 누룩의 첨가량이 많아질수록 명도의 L값은 약간 낮아지고 a값은 마이너스 값으로 초록색에 가깝고 황색도의 b값은 높아지는 경향성을 보였다. 맥주의 점도는 누룩의 첨가량이 많을수록 점도가 낮았다. 쓴맛 또한 누룩 첨가량이 많을수록 낮은 값이 나왔다. 아미노산도는 누룩 첨가구에서 더 높은 값이 나타났으나 첨가구내에서의 차이는 없었다. 거품 안정성은 대조구 135.62±10.28으로 N15는 368.24±23.25으로 대조군보다 2배 이상 유의적으로 차이 나는 결과를 보였다. 유리당의 포도당, 설탕, 엿당은 발효, 숙성과 숙성기간 동안 줄어들었고 유기산은 말산, 시트르산이 효모의 대사산물로 발효, 숙성, 저장 기간에 그 수치가 높아졌다. 누룩을 맥주당화과정의 효소제 역할로 이용한 실험결과를 통해 맥주 공정 중당화과정에 누룩을 첨가함으로 새로운 특성의 맥주가 생산될 수 있음을 확인하였다. Nuruk, a traditional Korean alcoholic beverage starter, was evaluated as an additional saccharifying agent comprising up to 1.5% (w/w) of malt weight in ale-type beer processing. Sample characteristics were monitored during fermentation, ripening, and storage. Beer containing nuruk showed higher numbers of total viable bacteria and yeast cell counts. Additionally, ethanol (6.19-6.35%), color (Standard Reference Method), foam stability (228.49-368.24 Σ), saccharogenic power (307-417), and reducing sugar (3.83-5.25%) increased as the amount of nuruk was increased, while viscosity (3.13-2.07 cP) and bitterness unit (19.68-13.13) were lower than in samples without nuruk. Overall acceptance and aftertaste of the beer were significantly higher in a preference test. These results demonstrate that nuruk can be used to produce a new type of ale.

요오드화 조영제에 의한 고정약진 1예

심지수 ( Jisu Shim ),정수지 ( Soojie Chung ),김건우 ( Gun Woo Kim ),손경희 ( Kyoung Hee Sohn ),김주영 ( Ju Young Kim ),강혜련 ( Hye Ryun Kang ) 대한천식알레르기학회(구 대한알레르기학회) 2015 Allergy Asthma & Respiratory Disease Vol.3 No.5

Iodinated contrast media (ICM) can cause not only immediate onset hypersensitivity but also delayed onset hypersensitivity. While the most common form of delayed onset hypersensitivity reaction to ICM is exanthematous eruption, fixed drug eruption (FDE) can occur rarely related to ICM. A 70-year-old male with liver cirrhosis and hepatocellular carcinoma repeatedly experienced erythematous patches on his right forearm and hand 6 hours after exposure to iopromide for computed tomography scan. ICM induced FDE was diagnosed clinically. Intradermal test with 6 kinds of ICM (iobitridol, iohexol, iomeprol, iopamidol, iopromide, and iodixanol) was performed and showed the weakest positive reaction to iohexol compared to the others in 48 hours. After changing iopromide to iohexol based on these results, FDE did not recur. We report here a case of iopromide induced FDE which was successfully prevented by changing ICM to iohexol based on intradermal test results. (Allergy Asthma Respir Dis 2015;3:375-379)

학교영어수업 만족도와 부모의 학업성과압력이 고등학생의 영어학습 동기와 행동에 미치는 영향 : 일반고와 특목고의 비교

최나야(Choi, Naya),정수지(Jung, Suji),박유미(Park, You-Me),정혜민(Chung, Hyemin) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.2

본 연구의 목적은 일반고와 어문계열 특목고 학생의 영어학습 실태를 파악하고, 학교 유형에 따라 학교영어수업 만족도와 부모의 학업성과압력이 영어학습 동기와 영어학습 행동에 미치는 영향에 차이가 있는지 알아보는 것이다. 서울, 경기, 충청, 경상, 강원지역의 일반고 5곳과 특목고 4곳에서 1, 2학년 학급을 무선 표집하여, 일반고 학생 283명과 특목고 학생 235명을 대상으로 질문지 조사를 실시하였다. 주요 연구 결과는 다음과 같다. 첫째, 일반고와 특목고 학생의 영어학습 관련 변인에 차이가 있었다. 영어학습 및 영어사교육 시작 시점, 영어권 해외경험, 유형별 영어학습 시간과 같은 영어학습 경험에서 두 집단 간 차이가 나타났다. 학교영어수업 만족도, 통합적 영어학습 동기, 영어학습 행동은 특목고 학생이 일반고 학생보다 높았지만, 부모의 학업성과압력은 일반고 집단에서 더 높았다. 둘째, 학교영어수업 만족도, 부모의 학업성과압력, 영어학습 동기가 영어학습 행동에 영향을 미치는 경로가 두 집단 간에 달랐다. 통합적 동기는 일반고 모형에서 부모의 학업성과압력이 영어학습 행동에 미치는 영향을 완전매개하였지만, 특목고 모형에서는 학교영어수업 만족도가 영어학습 행동에 미치는 영향을 완전매개하였다. 본 연구 결과는 다양한 학생의 학습권을 보장하는 교육정책 마련을 위한 기초자료로 활용될 수 있을 것이다. The purpose of this study was to compare English learning experiences and the effects of school English instruction and parents’ pressure for academic achievement on English learning motivation and behavior between general and special-purpose high school students. 283 general high school students and 235 special-purpose high schools students from five general high schools and four special-purpose high schools in Seoul, Gyeonggi, Chungcheong, Gyeongsang, and Gangwon district in South Korea participated in the study. The main findings of this study were as follows. First, there were differences in English learning experiences before and after high school entrance between general and special-purpose high school. Second, the paths that satisfaction with school English instruction and parents’ pressure for academic achievement had effects on student’s English learning motivation and behavior were different between two types of school. Third, integrative motivation fully mediated the effect of parents’ pressure for academic achievement on English learning behavior in general high school students, while integrative motivation fully mediated the effect of satisfaction with school English instruction on English learning behavior. The results of this study can be used as preliminary data to establish educational policy to guarantee learning rights of students with different needs.

대한천식알레르기학회 알레르기비염 진료지침: 파트 2. 비약물치료의 업데이트

박상철 ( Sang Chul Park ),정수지 ( Soo Jie Chung ),최정희 ( Jeong-hee Choi ),이용주 ( Yong Ju Lee ),양현종 ( Hyeon-jong Yang ),박도양 ( Do-yang Park ),김동규 ( Dong-kyu Kim ),이일환 ( Il Hwan Lee ),김수환 ( Soo Whan Kim ),김도현 ( 대한천식알레르기학회 2023 Allergy Asthma & Respiratory Disease Vol.11 No.3

Allergic rhinitis is the most common chronic disease worldwide. Various upper airway symptoms lower quality of life, and due to the recurrent symptoms, multiple treatments are usually attempted rather than one definitive treatment. There are alternatives to medical (medication-based) and nonmedical treatments. A guideline is needed to understand allergic rhinitis and develop an appropriate treatment plan. We have developed guidelines for medical treatment based on previous reports. The current guidelines herein are associated with the “KAAACI Evidence-Based Guidelines for Allergic Rhinitis in Korea, Part 1: Update in pharmacotherapy” in which we aimed to provide evidence-based recommendations for the medical treatment of allergic rhinitis. Part 2 focuses on nonpharmacological management, including allergen-specific immunotherapy, subcutaneous or sublingual immunotherapy, nasal saline irrigation, environmental management strategies, companion animal management, and nasal turbinate surgery. The evidence to support the treatment efficacy, safety, and selection has been systematically reviewed. However, larger controlled studies are needed to elevate the level of evidence to select rational non-medical therapeutic options for patients with allergic rhinitis. (Allergy Asthma Respir Dis 2023;11:126-134)

Cetuximab에 의한 아나필락시스를 보인 환자에서 성공적인 탈감작 적용 1예

원하경 ( Ha Kyeong Won ),문성도 ( Sung Do Moon ),심지수 ( Ji Su Shim ),정수지 ( Soo Jie Chung ),김건우 ( Gun Woo Kim ),김수정 ( Su Jeong Kim ),박한기 ( Han Ki Park ),강혜련 ( Hye Ryun Kang ) 대한소아알레르기호흡기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.4

Cetuximab, a chimeric mouse-human immunoglobulin, is an antiepidermal growth factor receptor monoclonal antibody. It has been approved by the U.S. Food and Drug Administration for the treatment of metastatic colorectal and head/neck cancer, but can cause fatal hypersensitivity reactions in some patients. A 66-year-old male with metastatic sigmoid cancer had cetuximab-induced anaphylaxis when the first dose of cetuximab was administered. Cetuximab was safely readministered for another 15 cycles based on the rapid desensitization protocol. We experienced a case of cetuximab-induced anaphylaxis on the first exposure which was successfully managed by rapid desensitization. (Allergy Asthma Respir Dis 2015;3:294-296)

여러 대의 스마트폰을 이용한 입체 음향 시스템

명창호(Myeong, Chang-Ho),유병현(Yoo, Byeong-Hyeon),박한별(Park, Han-Byeol),권용업(Kwon, Yong-Up),노영주(Noh, Young-Joo),정수지(Chung, Su-Jee),김기준(Kim, Ki-Jun),박호종(Park, Ho-Chong) 한국방송·미디어공학회 2014 한국방송공학회 학술발표대회 논문집 Vol.2014 No.6