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조직중의 잔류 diethylstilbestrol과 zeranol의 동시분석법에 관한 연구
Jong Myung Park(朴鍾鳴),In Cheon Kim(金仁千),Young Hwa Sim(沈暎和),Sang Hee Jeong(鄭詳憙),Sun Namgoong(南宮琁),Keun Sik Park(朴根植),Mun Han Lee(李文漢),Chang Up Lee(李昌業) 한국예방수의학회 1992 예방수의학회지 Vol.16 No.3
A simultaneous analysis method using GC/MS was developed to monitor residual DES and zeranol. The residues in tissues were determined by the method developed. The residues in tissues were homogenized with sodium acetate buffer, hydrolysed with β-glucuronidase and extracted with acetonitrile. Lipids in the extract were removed with dichloromethane, the solvent was evaporated and then the residues were redissolved in alcohol mixture. Sep-pak cartridge was applied for clean-up and the separated residues were derivatized using TMSI and BSTFA. The residues were determined by GC/MS with DB-5 column, helium as a carrier gas, electron impact ionization mode and TIC and SIM scan mode. The limit of detection was 1 ppb and the calibration curves showed good linearity.
복강경하 자궁각절제술과 자궁경부이형성증 병력있는 환자에서 임신 제3분기에 일어난 연속적인 자궁파열사례
김영란 ( Young Ran Kim ),문명진 ( Myung Jin Moon ),장성운 ( Sung Woon Chang ),안은희 ( Eun Hee Ahn ),장항용 ( Hang Yong Jang ),이경미 ( Gyong Mi Lee ),정상희 ( Sang Hee Jong ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.12
Uterine rupture during the course of pregnancy is an uncommon obstetric event. Rupture of an unscarred uterus is rare, whereas rupture of a scarred uterus is more common and is usually the result of a Cesarean section. Uterine rupture during pregnancy usually occurs in patient with a scarred uterus, and recurrent uterine rupture usually occurs at a prior ruptured site. However, recurrent uterine rupture that occurs at a different site, regardless of prior rupture site, has yet to be reported. The patient described in this case report had cervical dysplasia with positive for human papilloma virus (HPV) type 16. As the presence of a precancerous lesion in the cervix is reported to increase the risk of preterm birth and spontaneous uterine rupture, a possible correlation between recurrent uterine rupture and cervical dysplasia was considered for this patient.
엔로플록사신 액제의 닭유래 병원세균에 대한 시험관내 항균효과 시험
윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-
In this study the antimicrobial spectrum and sensitivity of a liquid formulation of enrofloxacin against the major six pathogenic bacteria isolated from the diseased poultry in Korea were evaluated in comparison with ciprfloxacin (CFX), gentamicin (GM) and penicillin (PC). A liquid form of enrofloxacin, a test material and ciprofloxacin showed at least 83% antibacterial activity against all of six test pathogenic microorganisms at the fixed concentration of 10 ㎍/㎖. Gentamicin and penicillin revealed much lower antibacterial activity at the same condition. We evaluated the liquid form of enrofloxacin as having widespread antibacterial spectrum against poultry infections. The liquid form of enrofloxacin showed potent antibacterial activity, with the MIC range being 0.12∼2 ㎍/㎖ against Gram positives, 0.06∼2 ㎍/㎖ against Gram negatives and 0.5∼2 ㎍/㎖ against Mycoplasma spp. These values were equivalent to or somewhat higher than those of ciprofloxacin, but much lower than those of gentamicn and penicillin. This new liquid form of enrofloxacin would find its way in application of mixing with drinking water for the prevention and treatment of diverse infections in chickens.
엔로플록사신 액제의 닭 호흡기 및 소화기 감염증에 대한 예방 및 치료효과
윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-
We evaluated the efficacy of the liquid form of enrofloxacin against poultry respiratory and digestive infections, the major problems in the poultry industry, from diverse diagnosis viewpoints. Results obtained through this study were as follows: 1. The liquid form of enrofloxacin showed good acceptability to poultry owing to no abhorrence to the drug by chickens, which indicated its suitability for mixing in drinking water. 2. The application of the enrofloxacin formulation improved the productivity of the chicken farm to a great extent by lowering the death toll of chicken raised in the farm. 3. The use of the drug shortened the days to the market, and increased the body weight at the time of marketing. 4. Preventive and therapeutic effects of the liquid enrofloxacin were observed higher than ampicillin, a major antibiotic used in poultry farming. From above results, the liquid form of enrofloxacin would find its use for the prevention and treatment of digestive and respiratory infections, let alone the growth promotion and feed efficiency, especially in the chicken farming practice.