Ethylene Oxide 폭로근로자들의 혈액학적 소견

정미홍,이용환 대한보건협회 1997 대한보건연구 Vol.23 No.2

의료기구의 소독시 많이 사용되는 산화에틸렌(ethylene oxide)에 대한 병원 근무자들의 폭로수준과 혈액 검사와의 관련성을 파악하기 위하여 부산시내 병원 4곳에서 산화에틸렌 가스 멸균실에 근무하는 34명을 폭로군으로, 산화에틸렌에 폭로된 경험이 없는 간호사 34명을 대조군으로 하여 본 연구를 시행하였다. 일반혈액검사는 Laser방식으로 흡광도를 이용하여 백혈구, 적혈구, 혈색소, 혈구용적치를 분석하였고 감별혈구계산(differentia lympho count)은 수작업으로 하였다. 산화에틸렌 농도 측정은 근로자의 호흡기 위치에서 개인용공기시료 포집장치(personal air sampler)를 이용하여 채취한 후 가스크로마토그래피로 분석하였다. 멸균실 근무근로자 34명의 평균 개인폭로량은 0.72ppm이었으며 이중 9명이 노출기준치(TLV-TWA)인 1ppm을 초과하는 농도에 폭로되고 있었고, 특히 주작업자 6명 중 3명이 노출기준치보다 높았다. 혈액학적 검사 결과 백혈구와 림프구에서 폭로군이 대조군보다 높았으며 그 외의 소견은 차이가 없었으며, 노출기준치 이하군과 이상군으로 분류하여 혈액학적 검사 결과를 비교하였을 때에는 모든 검사 항목에서 유의한 차이가 없었다. 헐액학적 검사 결과와 각 변수들간의 상관분석에서는 폭로수준과 근무기간간에 유의한 상관관계가 있었으며(r=0.52, p<0.05) 호중구와는 유의한 역상관관계가 있었다(r=-0.33, p<0.05). 조사대상 병원 4곳의 멸균실 근무자의 보호구 착용 실태는 미흡하였으며 안전에 관한 보건교육도 한 곳만 제외하고는 전혀 이루어지지 않고 있었다. 급성 폭로시 호흡기, 눈, 피부에 중상을 나타내고 만성폭로시 후각이상과 염색체 이상, 단백뇨, 자연유산을 증가, 백혈병 발생율이 증가되는 것으로 알려진 산화에틸렌 취급 근로자들에 대한 건강관리와 작업환경측정이 거의 이루어지지 않고 있는 현 실정에서 이상의 결과로 미루어 보아 산화에틸렌 사용 부서에 대한 작업환경측정과 근무자들에 대한 특수건강진단의 실시와 같은 대책이 시급히 마련되어야 할 것이며, 또한 근로자들의 보호구 착용과 안전교육이 병행 실시되어야 할 것이다. Ethylene oxide is widely used to sterilize heat-sensitive medical equipments. The relationship was studied between ethylene oxide exposure level and hematologic effects of the workers who were employed in sterilization room of the hospitals. From 4 hospitals in Pusan, thirty-four workers, who worked in sterilization room using ethylene oxide gas as sterilizers, were selected as exposed group, and as a control group, 34 nurses, who were never exposed to ethylene oxide, were participated in this study. Ethylene oxide was sampled by personal air sampler and analyzed by gas chromatography for determination of the personal exposure level and work environment level, and Complete Blood Count(CBC) and differential counts were included in hematologic tests. The mean personal exposure level was 0.72 ppm in the exposed group, and 9-persons in this group were exposed above the standard 1 ppm(TLV-TWA), especially 3 persons of 6 operators were above the standard. Though the hematologic results were all within normal range, white blood cell and lymphocytes in differential count were significantly higher in exposed group than in control group. When the exposure level was divided as below and above standard, there were no significant differences between them in hematologic tests. Also, exposure level and neutrophil in differential count showed significantly negative correlation to hematologic effects in correlation analysis. A few workers wore personal protective equipments and workers, only in one hospital, received health education on safety. From above results, it was suggested that periodical measurements for ethylene oxide in hospitals and health care programs were needed.

루푸스가 가져다준 새 기회

정미홍 샘터사 1997 월간 샘터 Vol.28 No.6

한·중 인식 양태 표현과 양태 부사의 결합양상 대조 - 확실성 정도를 중심으로

정미홍 한남대학교 한남어문학회 2020 한남어문학 Vol.41 No.-

본고는 한·중 인식 양태 표현과 양태 부사의 결합양상을 검토하여 이의 공통점과 차이점을 찾아내고, 한국어 인식 양태의 확실성 정도를 깊이 밝히 는 데에 목적이 있다. 여기서 한국어와 중국어 인식 양태 표현과 양태 부사 와 결합할 때 확실성 정도를 따라 규칙적인 공기관계가 이룰 수 있는지를 확인하기 위해 의미 중심적 접근방법을 통해 살펴봤다. 한국어 인식 양태 표현은 화자의 추측을 나타내며 확실성 정도도 함께 드러낸다. 중국어 인식 양태 표현은 화자의 추측을 표현하지만, 확실성 정 도를 표현할 때 정태동사 앞에 오는 양태 부사를 통해 실현하는 경우가 많다. 한국어 인식 양태는 확실성 정도가 낮은 부사와 결합할 경우에 확실 성 정도가 높은 부사와 결합할 수 없는 반면에, 중국어 인식 양태 중에 ‘要’ 와 ‘会’는 양태 부사와 결합할 때 확실성이 낮은 부사나 확실성이 높은 부사 나 모두 제약을 받지 않는 것으로 가장 큰 차이점으로 보인다. 이외에 한국 어 인식 양태와 중국어 인식 양태는 양태 부사와 결합할 때 그 확실성 정도 를 따라 규칙적인 공기관계가 이루어지는 점은 서로의 공통점으로 보인다. The purpose of this paper is to examine the combined patterns of Korean-Chinese recognition epistemic modality and modal adverbs to find commonalities and differences between them, and to clarify the degree of certainty of Korean epistemic modality. Here, when combining Korean and Chinese epistemic modality and modal adverbs, we examined through a semantic-oriented approach to see if a correspondent relationship can be achieved according to the degree of certainty. The epistemic modality of the Korean represents the speaker's guess and also reveals the degree of certainty. Epistemic modality in Chinese expresses the speaker's conjecture, but when expressing the degree of certainty, it is often realized through modal adverbs preceding the static verb. Korean epistemic modality can not be combined with highly certain adverbs when combined with low certainty adverbs, whereas ‘要’ and ‘会’ among Chinese epistemic modality are adverbs with low certainty or high certainty when combined with modal adverbs. That is the biggest difference between Korea epistemic modality and Chinese epistemic modality. In addition, other of the Korean epistemic modality and the Chinese epistemic modality form a correspondent relationship according to the degree of certainty when combined with modal adverbs, it seems to be a common point of each other.

대사증후군 진단기준에 따른 대사증후군 유병률 비교

이정식,정미홍,이명숙,유병철,이용환 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.1

Background : There is no internationally agreed definition for metabolic syndrome (MS) and, hence, estimates of MS vary substantially across populations depending on the criteria used. This study was performed to compare the prevalence of MS among Korean adults by International Diabetes Federation (IDF) definition with that by National Cholesterol Education Program Adult Treatment Panel Ⅲ (ATP Ⅲ). Methods : A total of 775 health screen examinees above 40 years old who were examined in Kosin University Gospel Hospital from September 2005 to February 2006 were enrolled in this study. The height, weight, waist circumference, and systolic and diastolic blood pressures of the subjects were examined and fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and triglyceride levels in venous blood were measured. According to the IDF definition, someone has the MS if he or she has central adiposity (≥90 cm (male), ≥80 cm (female)) plus two or more of the following four factors : 1) raised concentration of triglyceride ≥150 mg/dL; 2) reduced concentration of HDL cholesterol : <40 mg/dL in men and <50 mg/dL in women; 3) raised blood pressure : systolic blood pressure 130 mmHg or diastolic blood pressure ≥85 mmHg; 4) raised fasting glucose concentration ≥100 mg/dL. And the metabolic syndrome was defined as the presence of three or more of the following by ATP Ⅲ : waist circumference men ≥90 cm, women ≥80 cm, blood pressure ≥130/85 mmHg, fasting glucose ≥110 mg/dL, HDL cholesterol men <40 mg/dL, women <50 mg/dL, triglyceride ≥150 mg/dL. Results : Based on IDF definition, the prevalence of the MS was 26.6% among all participants, 23.3% among men, and 28.1% among women. Based on ATP Ⅲ definition, the prevalence of the MS was 26.1% among all participants, 23.3% among men, and 27.4% among women. The k satistic for the agreement between IDF and ATP Ⅲ definition was 0.80 in all participants, 0.75 in men, and 0.82 in women. The prevalence of the metabolic syndrome increased with aging in both men and women. Abdominal obesity and hypertension were most prevalent components in the MS. Conclusion : The prevalence of the MS was similar compared the criteria of IDF to ATP Ⅲ, and IDF definition for MS has a high concordance with the ATP Ⅲ definition.

대사증후군 환자에서 고감도 C-반응 단백의 성별차이

이상호,정미홍,이순례,유병철,이용환 고신대학교의과대학 2006 고신대학교 의과대학 학술지 Vol.21 No.2

Background: High-sensitivity C-reactive protein (hsCRP), the classic acute-phase reactant, is an extremely sensitive systemic marker of inflammation. A variety of factors seems to influence hsCRP levels. The aim of this study was to elucidate the gender differences in the association between hsCRP and features of the metabolic syndrome (MS) among Korean. Methods: The study population included 1,283 men and 3,265 women aged 40 years and over who were enrolled in Korean Health Examinee Cohort. They were examined in 10 General hospitals from November 2004 to September 2005. The height, weight, waist circumference, and systolic and diastolic blood pressure of the subjects were examined and on concentrations of fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, and hsCRP in peripheral venous blood were measured. Results: In both sexes, there were significant positive correlations between age, smoking, body mass index, waist circumference, systolic and diastolic blood pressure, triglyceride, and fasting glucose and hsCRP, whereas significant negative correlations were present between drinking, and HDL cholesterol and hsCRP. Mean concentrations of hsCRP in men with 0, 1, 2, 3, and ≥4 components of MS were 0.13, 0.16, 0.18, 0.20, and 0.22 mg/L, respectively. The respective mean concentrations of hsCRP for women were 0.08, 0.09, 0.12, 0.14 and 0.14 mg/L. Results of stratified analyses by the number of components of the metabolic syndrome of 0, 1, 2, 3, and ≥4 revealed that an increase in hsCRP concentrations was greater in men than women with an increased number of components of the MS. Conclusion: There was a difference in concentrations of hsCRP between men and women, and especially an increase in hsCRP concentrations associated with risk factor-clusteringof MS was more prnounced in men.

건설산업에서의 녹색기술과 기후변화 대응

송은수,정미홍 한국대기환경학회 2009 한국대기환경학회 학술대회논문집 Vol.2009 No.10월

공동주책 라이프싸이클 이산화탄소 산정 프로그램 (ECO-pia) 개발에 관한 연구

이강희 ( Kang Hee Lee ),류승훈 ( Seung Hun Ryu ),이은택 ( Eun Tack Lee ),정미홍 ( Mi Hong Jeong ) 한국전과정평가학회 2010 한국전과정평가학회지 Vol.11 No.1

1996년 제1차 정책포럼 토론요지

강대인 (토론자),이경자 (토론자),이종수 (토론자),이두원 (토론자),박성수 (토론자),김사승 (토론자),이근영 (토론자),한중광 (토론자),신경민 (토론자),신동준 (토론자),유재홍 (토론자),정미홍 (토론자),진성호 (토론자),이규환 (토론자),조기숙 (토론자),이효성 (토론자) 한국방송학회 1996 한국방송학회 세미나 및 보고서 Vol.- No.-