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RISS 인기검색어
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- 저자 : 정미홍 ( Mi Hong Jeong ) (검색결과 3 건)
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이상호,정미홍,이순례,유병철,이용환 고신대학교의과대학 2006 고신대학교 의과대학 학술지 Vol.21 No.2
Background: High-sensitivity C-reactive protein (hsCRP), the classic acute-phase reactant, is an extremely sensitive systemic marker of inflammation. A variety of factors seems to influence hsCRP levels. The aim of this study was to elucidate the gender differences in the association between hsCRP and features of the metabolic syndrome (MS) among Korean. Methods: The study population included 1,283 men and 3,265 women aged 40 years and over who were enrolled in Korean Health Examinee Cohort. They were examined in 10 General hospitals from November 2004 to September 2005. The height, weight, waist circumference, and systolic and diastolic blood pressure of the subjects were examined and on concentrations of fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, and hsCRP in peripheral venous blood were measured. Results: In both sexes, there were significant positive correlations between age, smoking, body mass index, waist circumference, systolic and diastolic blood pressure, triglyceride, and fasting glucose and hsCRP, whereas significant negative correlations were present between drinking, and HDL cholesterol and hsCRP. Mean concentrations of hsCRP in men with 0, 1, 2, 3, and ≥4 components of MS were 0.13, 0.16, 0.18, 0.20, and 0.22 mg/L, respectively. The respective mean concentrations of hsCRP for women were 0.08, 0.09, 0.12, 0.14 and 0.14 mg/L. Results of stratified analyses by the number of components of the metabolic syndrome of 0, 1, 2, 3, and ≥4 revealed that an increase in hsCRP concentrations was greater in men than women with an increased number of components of the MS. Conclusion: There was a difference in concentrations of hsCRP between men and women, and especially an increase in hsCRP concentrations associated with risk factor-clusteringof MS was more prnounced in men.
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이정식,정미홍,이명숙,유병철,이용환 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.1
Background : There is no internationally agreed definition for metabolic syndrome (MS) and, hence, estimates of MS vary substantially across populations depending on the criteria used. This study was performed to compare the prevalence of MS among Korean adults by International Diabetes Federation (IDF) definition with that by National Cholesterol Education Program Adult Treatment Panel Ⅲ (ATP Ⅲ). Methods : A total of 775 health screen examinees above 40 years old who were examined in Kosin University Gospel Hospital from September 2005 to February 2006 were enrolled in this study. The height, weight, waist circumference, and systolic and diastolic blood pressures of the subjects were examined and fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and triglyceride levels in venous blood were measured. According to the IDF definition, someone has the MS if he or she has central adiposity (≥90 cm (male), ≥80 cm (female)) plus two or more of the following four factors : 1) raised concentration of triglyceride ≥150 mg/dL; 2) reduced concentration of HDL cholesterol : <40 mg/dL in men and <50 mg/dL in women; 3) raised blood pressure : systolic blood pressure 130 mmHg or diastolic blood pressure ≥85 mmHg; 4) raised fasting glucose concentration ≥100 mg/dL. And the metabolic syndrome was defined as the presence of three or more of the following by ATP Ⅲ : waist circumference men ≥90 cm, women ≥80 cm, blood pressure ≥130/85 mmHg, fasting glucose ≥110 mg/dL, HDL cholesterol men <40 mg/dL, women <50 mg/dL, triglyceride ≥150 mg/dL. Results : Based on IDF definition, the prevalence of the MS was 26.6% among all participants, 23.3% among men, and 28.1% among women. Based on ATP Ⅲ definition, the prevalence of the MS was 26.1% among all participants, 23.3% among men, and 27.4% among women. The k satistic for the agreement between IDF and ATP Ⅲ definition was 0.80 in all participants, 0.75 in men, and 0.82 in women. The prevalence of the metabolic syndrome increased with aging in both men and women. Abdominal obesity and hypertension were most prevalent components in the MS. Conclusion : The prevalence of the MS was similar compared the criteria of IDF to ATP Ⅲ, and IDF definition for MS has a high concordance with the ATP Ⅲ definition.
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