"동의보감(東醫寶鑑)"."의학입문(醫學入門)"에 나타난 증제법(蒸製法) 운용에 관한 문헌적 고찰

정기훈,노성수,추병길,서영배,Jeong, Gi-Hoon,Roh, Seong-Soo,Choo, Byung-Kil,Seo, Young-Bae 대한한의학방제학회 2012 大韓韓醫學方劑學會誌 Vol.20 No.2

Objectives : provides the basis on steaming processing method (SPM) which was stated in 'Dongeuibogam' and 'Euihakipmun'. Methods : Drugs and prescriptions listed in 'Dongeuibogam' and 'Euihakipmun' were investigated by following criteria; (i) name and prescription of SPM-applied drugs, (ii) protocols on the use of the supporting materials, (iii) kind of supporting materials, (iv) processing period, (v) part of the herb plants, (vi) efficacy of herbal drugs, (vii) tastes of herbal drugs, (viii) meridian tropism of the herbal drugs. Results : 1. The number of herbs was 92 species of from 'Dongeuibogam', 87 from 'Euihakipmun', and the number of prescriptions was 197 from 'Dongeuibogam' and 119 from 'Euihakipmun'. 2. Infiltrating steaming and mixing and steaming procedures were used to process supporting materials. 3. The abundance of supporting materials was in the order of alcohol and ginger juice. 4. A twelve hour-period was most frequently used. 5. The herbal parts used most were in the order of fruit, seed, roots, and stem. 6. According to an efficacy category, a drug supplementing invigoration was used most frequently and a drug eliminating heat followed next. 7. Based on four spirit features, herbs showing warm, cold, and mild features were used most. 8. In considering five tastes, herbs showing sweet and bitter tastes were used most. 9. The herbs supporting the function of liver, kidneys, spleen, stomach, and lung were used in SPM. The herbs converging to the kidneys and the liver were conducted most in 'Dongeuibogam' and 'Euihakipmun' respectively. No case for herbal drug converging to 'Samcho' was reported. Conclusions : Our investigation on the use of SPM from 'Dongeuibogam' and 'Euihakipmun' revealed that there are special principles underlying the use of supporting materials, SPM period, parts and efficacy.

한국산(韓國産) 맥문동(麥門冬)의 포제방법(포製方法)에 따른 품질(品質) 비교(比較) 연구(硏究)

정기훈 ( Gi Hoon Jeong ),조은환 ( Eun Hwan Cho ),노성수 ( Seong Soo Roh ),서영배 ( Young Bae Seo ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.4

Objectives: Specifications by Processing Methods of Liriope platyphylla (LP) was not established in korea. We carried out method study for manufacture of LP. Above all, LP were purchased and were processed at four kinds. First group had hearts of swelling roots, not cut bodies(LP-A). Second group had not hearts of swelling roots, not cut bodies(LP-B). Third group had hearts of swelling roots, cut bodies(LP-C). Forth group had an aggregate of hearts of swelling roots(LP-D). Methods: We has gained losses on drying, contents of ethanol-soluble extracts, contents of water-soluble extracts and contents of spicatoside A. Results: 1. Losses on drying of all group were less than 18% that is a standard of chinese pharmacopoeia. 2. Contents of ethanol-soluble extracts at LP-C, LP-D were included more than contents of those in the other groups in significance levels. 3. Contents of water-soluble extracts at LP-A, LP-C were included more than contents of those in the other groups in significance levels. 4. Contents of spicatoside A in LP-B were included more than content of spicatoside A in the other groups in significance levels. Resultingly, standards of LP in korea were proposed compatible proposals suggested as below. 1. Losses on drying of LP were less than 15% that is less than that of chinese pharmacopoeia. 2. Form to boil in water must be cutting body with heart of swelling root. 3. Because there is no content of spicatoside A in heart of swelling root, it is not suited to purpose a index component. Conclusions: The subjects of loss on drying and form of LP to boil in water must be contained in korean pharmacopoeia. Moreover, because of much valuable LP in food and medicine, it is urgently required aspect of index component such as spicatoside B, spicatoside C, flavonoid, polysaccharide having medical actions and so on.

『뇌공포자론(雷公?炙論)』,『포자대법(?炙大法)』,『수사지남(修事指南)』에 나타난 증제법(蒸製法)에 관한 문헌적 고찰

정기훈 ( Jeong Gi Hoon ),노성수 ( Seong Soo Roh ),추병길 ( Byung Kil Choo ),서영배 ( Young Bae Seo ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.1

Objectives : Provides research basis on steaming processing method (SPM) as described in literatures ``Roegongpojaron``, ``Pojadaebub``, and ``Susajinam``, Methods : The following issues were considered for current investigation regarding herbal drugs: (i) categorizing SPM-applied drugs, (ii) protocols on the use of the supporting materials, (iii) kind of supporting materials, (iv) processing periods, (v) part of the herb plants, (vi) herbal efficacy, (vii) intrinsic properties and tastes of the herbal drugs, (viii) meridian tropism of the herbal drugs, Result : The number of herbal drugs was 70 species from ``Roegongpojaron``, 73 from ``Pojadaebub``, and 66 from ``Susajinam``. The abundance of supporting materials was in the order of alcohol, honey and tofu. The herbal parts of the roots, stem, fruit, and seed were most widely used. Based on herbal efficacy, a drug supplementing invigoration was used most, and a drug eliminating heat followed next. Based on four spirit features, herbs showing warm, cold, and mild features were used. In considering five tastes, herbs showing bitter and sweet tastes were used most. In considering meridian tropism, herbs converging to liver and kidneys were used, and drugs converging to ``Samcho, and gallbladder were not used, Conclusion : The present survey on SPM as described in ``Roegongpojaron``, Pojadaebub``, and ``Susajinam`` indicates that there is a principal specialty on the use of supporting materials, steaming periods, steaming parts and efficacy.

MUSP 운동치료와 전기치료가 척추측만증환자의 Cobb`s angle, 유연성, 균형능력 및 흉곽확장에 미치는 효과 비교

정기훈 ( Gi Hoon Jeong ),김은영(교신저자) ( Eun Young Kim ) 대한통합의학회 2016 대한통합의학회지 Vol.4 No.1

PURPOSE : The purpose of this study to suggest the exercise programs for improving the function and structure by applying the Masan university scoliosis program exercise method and electrical therapy method to the scoliosis patient. METHODS : The subjects were 18 patients who were diagnosed with scoliosis. They were randomly assigned either to a Masan university scoliosis program exercise group (n=11) that received Masan university scoliosis program exercise program or to a electrical therapy group (n=7). Flexibility, static balance, dynamic balance, and spinal angles were measured by using one leg standing with closed eyes, functional reach test, and Cobb``s angle, respectively. The chest expansion were calculated using differences of chest circumference between maximum inspiration and maximum expiration. RESULT : Masan university scoliosis program group before and after the intervention there was a difference in the static balance, spine angle(p<.05). Masan university scoliosis program group before and after the intervention there was a difference in the flexibility, static balance, spine angle, chest expansion (p<.05). CONCLUSION : These results revealed that Masan university scoliosis program exercise program improved flexibility, static standing balance, spine angle, used as scoliosis management and intervention. Therefore, it is expected to be used as a method for the treatment and prevention in the process of rehabilitation of patients with scoliosis.

불면증에서 산조인의 유무에 따른 약물배오의 경향성 고찰

이원융,정기훈,Lee, Won-Yung,Jeong, Gi-Hoon 대한한의학방제학회 2014 大韓韓醫學方劑學會誌 Vol.22 No.1

Objectives : Zizyphi spinosi Semen is widely used for treating insomnia in korea and other oriental country. This study is analyzing combination tendency of Zizyphi spinosi Semen in herbal formula for treating insomnia. Methods : Herbal formulas for treating insomia were searched in "The Prescription Dictionary of Traditional Chinese Medicine", and checked in each literary source. Then, the herbal formula was divided in two groups : FCZ(The formula group containing Zizyphi spinosi Semen) and FWZ(The formula group without Zizyphi spinosi Semen). FCZ and FWZ were compared by following criteria; i) Prevalence of herbal formula by period ii) Prevalence of medicinal material's effects iii) Prevalence of medicinal material iv) Prevalence of the nature of midicinals v) Prevalence of flavor of medicinals vi) Prevalence of meridian entry. Results : 116 Herbal formula met our criteria, and herbal formulas were divided in two groups : FCZ(n=59), FWZ(n=57). The result of prevalence in FCZ is following; Herbal formula prevalence increased as time passed to the Qing(淸) dynasty. Tonifying and replenishing medicinal(補益藥), tranquillizing medicinal (安神藥), and inducing diuresis to drain dampness medicinal(利水?濕藥) are the three most prevalent types of materia medica. In specifically, Panax ginseng radix(人蔘), Liriopis Tuber(麥門冬), Angelicae Gigantis Radix(當歸), Poria Cocos(茯神), Glycyrrhizae Radix(甘草), Poria cocos(茯神), Polygalae Radix(遠志), Thuja Orientalis L.(柏子仁), Paeonia Japonica(白芍藥), and HgS(?砂) are combined frequently. The most prevalent nature of medicinals were 'warm microwarm(溫 微溫)' and flavor of medicinals was normal(平). Meridian entrys that frequently combined were heart(心), spleen(脾), and liver(肝). Conclusion : We found combination tendency of Zizyphi Semen in herbal formula for treating insomnia.

온담탕(溫膽湯)의 방론(方論)에 관한 고찰

최웅식,정기훈,Choe, Ung-Sik,Jeong, Gi-Hoon 대한한의학방제학회 2014 大韓韓醫學方劑學會誌 Vol.22 No.1

Objectives : The purpose of this study was to investigate the interpretation of the Ondam-tang(Ondam-tang, here-in-after referred to as "ODT") prescription in order to obtain the evidence for clinical applications. Methods : We have analyzed the interpretation on the ODT prescription through translations and comparisons based on classic books about the oriental medical prescriptions. Result : 1. ODT was first mentioned in the Jiyangfang(集驗方) which was quoted in the Waitaimiyao (外臺秘要). After that, in book Sanyinjiyibingzhengfanglun(三因極一病證方論), Chen-yan(陳言) completed and recorded in a book organizing prescriptions of ODT now in frequent use. 2. The Banha(半夏) removes the dam(痰-phlegm) and relieves emesis. The Jinpee(陳皮) encourages strengths, and the Bokryoung composes oneself and produces the water. The Licorice(甘草) relieves people's mind, and the Ginger relieves gastrointestinal problems and relieves emesis. Juk-yeo(竹茹) abate of the fever of the Sangcho(上焦). Jisil(枳實) encourages strength, controlling Samcho(三焦) as releasing the congestion of energy. In these ways, numerous symptoms resulted from the imbalances of the Gallbladder(膽) are treated. 3. Meaning of "on(溫-warm)" in ODT regains the original characteristic of the Gallbladder(膽). 4. Treatment mechanism of ODT is 'cooling the Gallbladder(膽)' and 'remedies Samcho(三焦)' and 'eliminates dam(痰)' and 'cure Kiwool(氣鬱-which is kind of depressions) and Saengyen(生涎-which is kind of phlegm)' and 'removes a mismatch between Gallbladder(膽) and Stomache(胃)'. Conclusion : In this study, we have demonstrated various methodologies. This paper will be useful to the future researchers and clinicians to conduct a study on herbal medicines such as the ODT.

소요산의 방론에 대한 고찰

이원융,정기훈,Lee, Won Yung,Jeong, Gi Hoon 대한한의학방제학회 2017 大韓韓醫學方劑學會誌 Vol.25 No.2

Objectives : The purpose of this study was to investigate the interpretation of the Soyo-san(SYS) prescription in order to obtain the evidence for clinical applications. Methods and Result : We interpreted on the SYS-related contents based on 25 classic books, analyzed it according to followed categories ; meaning of name, alteration of herbal composition according to age, usage, origin, physiological and pathological situation of SYS, description of each herbal drug Conclusion : 1. So(逍) mean diminish(消), 遙 mean roll(搖). It reflected feature of SYS, that alleviate depression without impairing vital energy(正氣). 2. SYS was first mentioned in the prescription of peaceful benevolent dispensary(太平惠民和劑局方), its essential application was harminizing liver depression and spleen deficiency(肝鬱脾虛) 3. SYS originated from Sayuk-san. Sayuk-san was appropriate for soothe the liver and regulate the spleen(疏肝理脾), while SYS was suitable for depressed liver and blood deficiency(肝鬱血虛) 4. Most medical literature insisted that application situation of SYS is blood deficiency(血虛), depressed liver(肝鬱), spleen deficiency(脾虛). And there is strong correlation between three factors. 5. Bupleurum falcatum L.(柴胡), Mentha arvensis L.(薄荷) alleviates liver depression as "pungent dissipate-qi uprais (辛散氣升)" nature. Angelica gigas Nakai(當歸), Paeonia lactiflora Pall.(白芍藥) emoliates the liver by nourishing the blood. Atractylodes japonica Koidz. ex Kitam.(白朮), Poria cocos(茯?), Glycyrrhiza uralensis Fisch.(甘草), Zingiber officinale Roscoe(生薑) cultivate the basis as tonifying earth(補土).

대승기탕의 방론에 대한 고찰

한상곤,서영배,정기훈,Han, Sang-Gon,Seo, Young-Bae,Jeong, Gi-Hoon 대한한의학방제학회 2016 大韓韓醫學方劑學會誌 Vol.24 No.3

Objectives : The purpose of this study was to investigate the interpretation of the Daeseunggi-tang(DST) in order to obtain the evidence for clinical applications.Methods and Results : We have analyzed the interpretation on the DST through translations and comparisons based on classic books about the oriental medical prescriptions.Conclusion : 1. 'Dae(大)' in DST means 'strong symptoms' or 'strong efficacy'. 'Seung(承)' in DST means 'smooth (順)', 'attach(連)' and 'serve(奉)'. 2. The main pathogenesis of DST's syndrome are heat binding(熱結)·qi stagnation(氣滯). 3. The main areas where disease pattern of DST is 'Yang brightness(陽明)'. It is also associated with 'Lesser yin (少陰)', 'Qi aspect(氣分)·Blood aspect(血分)' and 'Triple Energizer(三焦)'. 4. Laxative the Rhei Radix et Rhizoma(大黃) is sovereign medicinal(君藥) of DST, because of removing the heat binding(熱結) and the heat that spread throughout the body.

석고(石膏)가 streptozotocin 으로 유발된 rat의 당뇨병성(糖尿炳性) 신증(腎症)에 미치는 영향(影響)

홍광해,이권호,정기훈,김용성,이현주,Hong, Gwang-Hae,Lee, Kwun-Ho,Jeong, Gi-Hoon,Kim, Young-Seong,Lee, Hyun-Ju 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.4

Objectives : The aim of present study was to investigate recovery effects of gypsum, which has been used clinically in diabetes therapy. Methods : We established three groups, normal, control, and gypsum, and assigned 6 rats to each group. The normal group was not treated by any process and fed normal saline. The control & gypsum groups were administered streptozotocin(STZ) to induce diabetes. Gypsum extract was orally administered to the gypsum group for 10 days. After 8 weeks, the rats were sacrificed and their body weight, 24hrs urinary protein excretion, glucose, albumin, BUN, creatinine, total-cholesterol, LDL-cholesterol, triglyceride in blood, level of glycation end-product (AGE) and transforming growth factor ($TGF-{\beta}1$) in serum were measured. Morphological profiles and morphometric studies of the kidney cortex. renal transforming growth factor ($TGF-{\beta}1$) expression, macrophage/monocyte antigen (ED-1), and type IV collagen expression were studied. Results : The following results were obtained. The protein amount in urine per 24hrs of the gypsum-treated group as compared to the control was significantly reduced. The BUN and creatinine level in serum of the gypsum-treated group as compared to the control was significantly inhibited. The construction change in the kidneys of the gypsum-treated group as compared to the control was significantly inhibited. The factor of the gypsum-treated group as compared to the control was significantly inhibited. which induced the structural change in the kidneys. Conclusions : The above results suggest that gypsum partially improved kidney function.

평위산의 방론에 대한 고찰

최웅식,이원융,정기훈,서영배,Choe, Ung-Sik,Lee, Won-Yung,Jeong, Gi-Hoon,Seo, Young-Bae 대한한의학방제학회 2015 大韓韓醫學方劑學會誌 Vol.23 No.2

Objectives : The purpose of this study was to investigate the interpretation of the Pyeongwi-san(PWS) prescription in order to obtain the evidence for clinical applications. Methods and Result : We interpreted on the PWS-related contents based on 15 classic books, analyzed it according to followed categories ; origin, indication and precaution, usage, meaning of name, physiological and pathological situation of PWS, explain about each herbs. Conclusion : 1. PWS was first mentioned in the Bakjebang, its application was enhancing appetite. Application of PWS not only expanded digestive disease, infectious disease, and pain in articular, but also used to toniyfing drug. 2. Generous application method of PWS was ‘Sujunbok(水煎服)’. Pill preparation(丸劑) and decoction with salt(鹽湯劑) were also used 3. "Pyeongwi(平胃)“ in PWS means "flatten the stomach". There are some theory about methodology to "Pyeongwi (平胃)“, one is "drain the pathogen in stomach(敦阜說)”, other is "tonifying stomach's healthy qi(卑監說)“, the other is compromise theory. 4. Most medical literature related application situation of PWS to dampness(濕邪) in stomach. In Gangsulwongobangsunju, there are more detailed explain focused on metal qi(金氣), and fire qi(火氣) 5. Atractylodes japonica Koidz(蒼朮) drys dampness and fortifys the spleen, Magnolia officinalis Rehder(厚朴) eliminates dampness and treats fullness, Citrus reticulata Blanco(陳皮) moves and drains qi, Glycyrrhiza uralensis Fisch(甘草) tonify and harmonize in herbal formula