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김용일,안종훈,장세진,이동후,함준수,이종철,박문향,홍은경,전재범,기춘석,박경남,임병성 대한내과학회 1990 대한내과학회지 Vol.39 No.4
Alpha-fetoprotein (AFP) is well-known as a useful tumor marker, especially for hepatocellular carcinoma and yolk sac tumors, and there are many kinds of neoplasms that produce AFP, with gastric adenocarcinoma being the most common. In 1970, Bourreille et al. reported the first case of stomach cancer with an elevated AFP level. In 1985, Ishikura et al. reported that an AFP-producing gastric adenocarcinoma had features of hepatic differentiation and proposed that such gastric carcinomas should be collectively called $quot;Hepatoid Adenocarcinomas of the Stomach$quot;. We experienced a case of so-called hepatoid adenocarcinoma of the stomach in a 54-year-old male patient, who was diagnosed as double primary cancer of gastric adenocarcinoma and hepatoma and who underwent a subtotal gastrectomy and right lobectomy of the liver. We report this case with a review of the literature.