第4腦室에 發生한 Myxopapillary Ependymoma 1例

全東輝,朴舜河,李基燦,李大一 中央醫學社 1973 中央醫學 Vol.24 No.3

Many clinical and pathological studies of ependymoma have been studied in the past. Ependymomas were classified as follows by Kernohan; 1. Papilloma choroideum 2. Myxopapillary ependymoma 3. Epithelial ependymoma 4. Cellular ependymoma. Among them Myxopapillary type apparently arise from the film terminale andl very rarely found in the region of the ventricle of the brain. We are reporting this rare case of Myxopapillary ependymoma in 4th ventricle which has had vague clinical courses.and literature reviewed.

두개강내 악성 기형종 1예

전동휘,주정화,이기찬,최호익 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.1

A teratoma is a true tumor or neoplasm composed of multiple tissue of kinds foreign to the part in which it arises. Predilection site of intracranial teratoma are the pineal body, the pituitary region and the posterior fossa in order of frequency. We have reported a case of teratoma experienced in a boy aged 12 who disclosed various clinical manifestations of right frontal lobe tumor. The teratoma was malignant histologically and located deeply in the white matter of the right posterior frontal lobe.

골파괴성 Dumb-bell형 뇌수막종 1예

전동휘,주정화,이기찬,노순성,최호익 대한신경외과학회 1976 Journal of Korean neurosurgical society Vol.5 No.1

A 37-year-old Korean male was admitted to the hospital in December 1976 because of a slow growing hard mass in the right frontoparietal region near the midline. The patient had noted the mass accidentally while combing his hair six years prior to admission. Since then, the mass had grown slowly but progressively. On admission, there was a hard ovoid mass, 9 by 7 cm in size, over the right frontoparietal region, projecting 3 to 4 cm above the normal level of the skull. Skull roentgenogram disclosed a large area of bone destruction and defect, 8 by 6 cm, in size at the site of the tumor, accompanying sclerosis along the margin of the bony defect. A tumor located in extracalvarial portion of the head was a well circumscribed one, 9×7×4 cm in size, with no bone tissue over the tumor. A tumor located in intracranial portion was also a well circumscribed one measuring 5×4×3 cm, compressing the brain but not infiltrating. Extracalvarial and intracranial portions of the tumor were interconnected by the pedicle which was a part of the tumor and passed through the defect of the dura mater, 3 cm in diameter, nearly in the center of the bony defect. The tumor, dumb-bell formed in extracalvarial and intracranial growths, was completely excised. Pathological diagnosis of the specimen was fibroblastic meningioma.

경부내경동맥에 발생한 섬유근성이형성 1예

전동휘,주정화,이기찬,김성학 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.2

A case is presented in which left-sided hemiparesis was caused by a fibromuscular dysplasia of the right internal carotid artery in the neck, and is used as a basis for discussion of the angiographic features. The 24-year-old woman was admitted to our Department of Neurosurgery, Korea University hospital, with the complaints of headache and left-sided hemiparesis which developed abruptly about one month before this admission. The carotid angiography was performed by puncture of the right common carotid artery under the clinical impression of cerebral thrombosis. which showed no gross intracranial abnormalities. But the characteristic findings were observed under extracranial right internal carotid artery by demonstrating alternating zones of narrowing and widening of the arterial lumen which are so-called loose stocking appearance or 'string of beads' appearance and are the typical feature of fibromuscular dysplasia. No surgical interventions such as arterial reconstruction and grafting, or arterial dilatation with bougies were applied on the patient, and she was discharged from the hospital three days after the admission. Fibromuscular dysplasia is a rare sclerotic, noninflammatory lesion of unknown etiology involving the wall of large arteries. This disease is found most frequently in early adult life and women are afflicted more often than men. This condition has been described most often in the renal arteries, where it has been found to be a cause of hypertension. Among the involvement of carotid system, the cervical portion of the internal carotid artery is most often affected, and the involvements are often bilateral. When localized to the internal carotid arteries, it can give symtoms of intermittent or permanent cerebral ischemia, but is usually asymptomatic. The typical angiographic appearance is the main parameter for diagnosis of fibromuscular dysplasia.

실험적뇌부종

전동휘 고려대학교 의과대학 1975 고려대 의대 잡지 Vol.12 No.1

The studies of the occurence and changes of expermental brain edema have been observed by calculating wet weight, volume, dry weight, and percentage of both water content and swelling in 12 normal rabbits as a control group and 66 rabbit of expermental group. The brain edema was induced by expansion of laminaria which resulted in brain compression, that was inserted into the intracranial extradural space of rabbit, and also, the brain edema with swelling were induced by intravenous injection of distilled-water and intramuscular injection of pitressin. The effect of mannitol and steroid to these experimental brain edema and especially, the effect and reaction of ethanol and dilantin to brain edema were studied and the results obtained are as follows: The average wet weight of cerebral hemisphere of normal rabbits was 3.30±0.19gm. The average dry weight of 156 hemispheres of 78 rabbits was 0.69±0.04gm, while it’s volume was 2.97±0.29㎖ and the percentage of water content was 78.92±1.36 per cent. The weight, volume, and percentages of water content and swelling in the compressed sides of hemisphere showed higher values compared them to the opposite noncompressed hemisphere in the "laminaria compression" group and showed gradually increasing tendency as the time elapsed. The effect of mannitolization to "laminaria compression" group showed anti-brain edema reaction while there showed no such effect after steroid injection. The acute brain edema was demonstrated in pitressin and distilled-water group by showing increased percentages of water content and swelling per cent of the hemisphere than those of control group. Although the intravenous dilantin injection to these experimental groups showed no appreciable effect on antibrain edema, the ethanol showed significant anti-brain edema reaction and effect.

뇌부종에 대한 실험적 연구 : 제1보 Part 1

전동휘,최호익,이훈갑,이기찬,주정화 대한신경외과학회 1974 Journal of Korean neurosurgical society Vol.3 No.2

The studies of the occurence and changes of experimental brain edema have been observed by calculating wet weight, volume, dry weight, per cent water content and swelling per cent in 12 normal rabbits as a control group and 24 rabbits of experimental group. The brain edema was induced by expansion of laminaria which resulted in brain compression, that was inserted into the supratentorial extradural space of rabbit. The piece of section of laminaria which is a sea weed and used for the purpose of slow expanding space-occupying mass has a characteristic mode of slow expansion in volume on contact with water. The average wet weight of cerebral hemisphere of normal rabbits was 3.30±0.19gm. The average dry weight of unilateral hemisphere of 156 from 78 rabbits was 0.69±0.04 gm, while its volume was 2.97±0.29㎖ and the percentages of water content was 78.92±1.36 per cent. The weight, volume and percentages of water content and swelling in the compressed sides of hemisphere showed higher values compared them to the opposite noncompressed hemisphere in the "laminaria-compression.' group and showed gradually increasing tendency in the values as the time elapsed.

頭部損傷患者의 鹽類 및 水分代謝에 關한 臨床的 考察

全東輝 대한신경외과학회 1972 Journal of Korean neurosurgical society Vol.1 No.1

This report is a study on metabolic responces of selected forty five head injured patients which were admitted to neurosurgical department of Woo Sok Hospital C.H. from January to August 70. The study was undertaken in an attempts to estabilish the basis for electrolyte or water support to head injury patient. All patients were classified into five groups according to severity of head injury. Author studied on sodium, choloride and potasium of serum and urine at 24, 48, and 72hrs. N.P.O, in each group, and also considered the factors and mechanism, inducing hyponatremia of head injury patient, by virtue of count of either dilution or concentration of inorganic acid and protein anion which were mainly depend on water content of blood. The electrolytes were measured by the EEL flame photometery and chloride was measured by the Schales method. The characteristics of metabolic responces in electrolytes of each group are as following the results obtained. The persistent metabolic responces of head injured patients were found as mild to moderate hyponatremia compare with other site injured one and which were also depended on the severity of head injury, acuteness of its onset, the presence or abscence of brain parenchyma) destruction and brain swelling. The inducing factors of hyponatremia would be censiderld as follows.: 1) Water retention 2) Renal Na loss 3) Intracellular Na migration from blood.

실험적 뇌부종 : 제3보 Part Ⅲ

전동휘,주인수,김결,이기찬,주정화 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

The cerebral compression and edema were successfully produced by the expansion of the stalk of laminaria in the right epidural space of the rabbits. By weighting the wet and dry brain tissues, and by calculating the percentage of water content and that of swelling, with the rate of per cent water content to that of control group, the studies of the occurence and changes of experimental brain edema have been observed. In the normal rabbits, the average per cent water content of cerebral gray and white matters were 79.9±0.7% and 73.0±1.0%, respectively. The percentage of water content and swelling of cerebral gray and white matters in the compression site showed higher values than those in control group. As compared with normal group, the rate of per cent water content of cerebral gray matter at the site of compression showed gradual increasing tendency as time elapsed by 24 hours, while that of white matter demonstrated rapid increased of it by 6 hours and decreased gradually thereafter. And it appeared that the value of the cerebral white matter showed higher than that of gray matter throughout the period of 24 hour's compression. Cerebral edema induced by laminaria compression was more evient and severe in the white matter than in the gray, which was more striking at the early stage of cerebral compression.

뇌척수액에 대한 실험적 연구 : 제1보 지주막하 출혈액의 연령측정을 위한 면역학적 연구 Part Ⅰ Immunological Assessment of Age of Bloody Cerebrospinal Fluid

전동휘,이기찬,주정화,황적준 대한신경외과학회 1976 Journal of Korean neurosurgical society Vol.5 No.2

Bleeding into the subarachnoid space is one of frequent complications in neurosurgical practice and most frequently caused by rupture of meningeal vessels by trauma to the head. Hemorrhage into the subarachnoid space may occur in patient with blood dyscrasias, intracranial tumors, vascular anomalies, certain toxic or infectious diseases of the nervous system, and intracerebral hemorrhages. It may be worthy for academic interest and clinical practice to estimate the age of blood after hemorrhage into cerebrospinal fluid (CSF). The age was estimated and assessed by an immunological method with hemoagglutination activity using native Korean phytoagglutinin. The age of the red blood cells in RBC-CSF suspension of normal subjects was assessed and estimated by the hemoagglutination of phytoagglutinin in vitro. Vicia PHA and Clerodendron PHA chosen from among 18 different varieties of PHA are panhemoagglutinin and demonstrated the agglutination reaction most effectively. The agglutination activity of PHA with RBC-CSF suspension decreased gradually as time elapsed and activity subsided on 7∼8 th day. The age of RBC in CSF can be estimated by titration. The agglutination activity of PHA to RBC in CSF suspension continued for a longer period than that of PHA to either RBC in normal saline or anti-serum A and B in CSF. It would be well to say that the experimental results can he applied to clinical situations, especially subarachnoid hemorrhage.

측뇌실-복강 문합술 후 합병된 복수 및 수흉 1례

전동휘,주정화,이기찬,최종구,최용일 대한신경외과학회 1976 Journal of Korean neurosurgical society Vol.5 No.2

The majority of current shunting procedures involve wither a ventriculoperitoneal or a ventriculoatrial placement. The ventriculoperitoneal placement have less serious associated morbidity than the atrial placement hut revision of the placement is occasionally requested by complications associated with the shunting procedure. A case of ventriculoperitoneal shunt complicated by ascitis and hydrothorax was reported, in which the shunting procedure was indicated for relief of hydrocephalus in an infant.