아세트아미노펜 독성평가를 위한 μCCA-μGI 디바이스의 개발

장정윤,Chang Jung-Yun,Shuler Michael L. 한국약제학회 2006 Journal of Pharmaceutical Investigation Vol.36 No.4

Deficiencies in the early ADMET(absorption, distribution, metabolism, elimination and toxicity) information on drug candidate extract a significant economic penalty on pharmaceutical firms. Microscale cell culture analogue-microscale gastrointestinal(${\mu}CCA-{\mu}GI$) device using Caco 2, L2 and HEp G2/C3A cells, which mimic metabolic process after absorption occurring in humans was used to investigate the toxicity of the model chemical, acetaminophen(AAP). The toxicity of acetaminophen determined after induction of CYP 1A1/2 in Caco 2 cells was not significant. In a coculture system, although no significant reduction in viability of HEp G2/C3A and L2 cells was found, approximately 5 fold increase in the CYP 1A1/2 activity was observed. These results appear to be related to organ-organ interaction. The oral administration of a drug requires addition of the absorption process through small intestine to the current ${\mu}CCA$ device. Therefore, a perfusion coculture system was employed for the evaluation of the absolution across the small intestine and resulting toxicity in the liver and lung. This system give comprehensive and physiologic information on oral uptake and resulting toxicity as in the body. The current ${\mu}CCA$ device can be used to demonstrate the toxic effect due to organ to organ interaction after oral administration,

예비유아교사의 그림책에 대한 이미지 변화

장정윤(Chang Jung Yoon),안혜정(AHN HYE JUNG) 한국육아지원학회 2016 육아지원연구 Vol.11 No.4

본 연구는 그림책 수업을 통해 예비유아교사들의 ‘그림책’에 대한 수업 전․후의 이미지 변화를 파악하 는 것이 목적이다. 연구대상은 3년제 대학 유아교육과 전공심화과정 학생 54명으로 학기 초와 학기 말에 그림책에 대한 이미지를 그림으로 표현하고, 이에 대한 설명을 작성한 자료를 수집하여 내용분석을 실시 하였다. 그 결과 예비유아교사들의 그림책에 대한 이미지 변화는 개인적인 경험과 그림책 자체의 두 가지 측면으로 나타났다. 개인적인 경험에 대한 이미지는 ‘엄마, 아빠가 읽어주던 그림책에서 내가 읽는 그림 책으로’와 ‘아이들에게 들려주기만 하는 그림책이 아닌 내가 되새기며 읽어주는 그림책으로’ 범주화되었 다. 그림책 자체에 대한 이미지는 ‘그림책 역할에 대한 고정된 관점에서 폭넓은 관점으로’와 ‘그림책 구성 에 대한 표면적인 관점에서 유기적인 관점으로’ 범주화되었다. 이와 같은 연구결과는 예비유아교사의 그 림책에 대한 태도 형성과 그에 따른 바람직한 교수학습방법을 준비하기 위한 교사교육의 방향성을 제공 할 수 있을 것이다. The purpose of this study is to investigate changes in the image of ‘picture books’ perceived by preservice early childhood teachers before and after conducting classes using picture books. The participants were 54 preservice early childhood teachers enrolled in the advance course in early childhood education in a three-year college. At the beginning and the end of the semester, the participants were asked to draw the image they had about picture books and write a description, and the data were collected and analyzed using contents analysis. In the result, the changes in the image of picture books perceived by preservice early childhood teachers were divided into two aspects: first, regarding the personal experience, the perceived image of picture books changed ‘from pictures books my parents read to me, to ones I read to children,’ and ‘from picture books I read to children, to ones I want to ruminate about picture books’ Second, regarding the images of picture books, the changes were categorized into:‘from a fixed view to a broad view of the roles of picture books’ and ‘from a superficial view to a view of organic relationship about the composition of picture books’ The findings of the study can help to improve an attitude of early childhood teachers toward picture books and provide a direction for training the teachers with an appropriate teaching and learning methods.

OSMU 방식을 적용한 무용작품 <피아노>의 창작과정 연구

장정윤 ( Chung Yoon Chang ) 한국무용기록학회 2011 무용역사기록학 Vol.23 No.-

이 연구는 실기주도연구(practice-led research)의 한 형태로 무용작품 <피아노>가 형성되기까지의 과정을 제시(writing and presenting)하며, 형성된 작품의 분석과 해석에 관해 고찰한 것이다. 문화콘텐츠를 개발하기 위한 OSMU 방식을 무용의 작품형성과정에 적용하고 안무방식을 확보하기 위해 영화(The Piano, 제인 캠프만 감독)에서 이야기 거리를 찾아 무용(피아노, 장정윤 안무, 2011)의 매체에 적합한 양식으로 작품화하였다. 오늘날 무용 창작공연을 위한 새로운 이야기 형식에 적극적으로 참여하고 관객이 작품을 일방적으로 수용하도록 하는 일에서 탈피하며, 관객과 무용의 상호작용에 의해 작품의 창조에 관객을 참여시키고자 한다는 데에 연구의 필요성을 두고 있다. 현시대적 배경과 현대사회의 대중을 겨냥하여 현대무용으로서 가능한 텍스트와 텍스트의 변형, 극적 내러티브, 그리고 이와 관련된 상호성에 관해 고찰하였다. 그렇게 해서 무용학 연구에 있어서 의도하는 실기를 통한 개념적 지식의 발견과 재해석에 관해 모색하고 실기주도연구의 방법과 가능성을 열고자 하는 것이다. 공연과 그 실천의 현상을 연구하는 데에 그치지 않고 공연 이후의 사고와 의식의 경험으로부터 한 발 더 나아가 새로운 개념과 이론을 발전시킨다는 데서 그 가치를 지니고 있다. This paper discusses on relationship of the storytelling film, <The Piano> directed by Jane Campion as One Source and producing contents of the dance, <Piano> as Multiple Use. It also discusses the dance``s structure, plot, spacial design, character, movement and choreographic ideas comparing to the picture``s, <Piano> shows the cultural interaction, characters`` interaction with audience, dancer and choreographers, and ideological interaction which derives from different historical and temporal background. <Piano>is choreographed focusing on the spacial design and expressive movements, The expression of imaginary situation, motif, character, emotion are more important than the description of fact and incidents. The script used for the picture, deals with the storytelling of the dance accompanying the interacting forces of choreographer, dancers, and audience. The experience of time, changes of situation and imagination for choreographer is not supposed to correspond to the scriptor``s as well as audience`s, intending to destroy the bored between the audience and performance. The integration of narrative elements of film, <The Piano> and interactive elements of choreographer will suggest the visual communicative form of narrative image. Three important concepts are found through choreographic procedure: 1) narrative and storytelling for growth from conventional storytelling of dance drama, 2) interactive and intertextuality for the integration of interacting forces of dance, and 3) rediscovery of body and its core as media in theatric arts intensifying experiences of informational reception, recognition and subjectivity. The choreographic ideas of recreation of Ada, recomposition of <The Piano> story and proper movement created for dancers, are found by manipulating of characters, incidents and situational motifs.

마사 그레이엄과 니체의 미학

장정윤 ( Chung Yoon Chang ) 한국무용기록학회 2013 무용역사기록학 Vol.31 No.-

니체철학에서의‘춤’은 철학적 논리를 설명하기 위한 개념으로서‘해방’,‘자유’,‘영원성’, ‘디오니소스적인 것’등의 추상적 관념을 상징한다. 니체에 있어서 무용수의 몸과 춤은 현실적인 것, 경험적인 것으로서 주요한 연구대상일 뿐만 아니라 니체사상의 주요한 주제이다. 본 연구는 니체철학의 영향을 받은 현대무용의 안무자들 가운데 마사 그레이엄(Martha Graham, 1894-1991)의 무용을 고찰하고, 그레이엄의 무용세계에 미친 니체의 영향을 알아보기 위한 것이다. 니체의 철학과 사유를 통해 마사 그레이엄의 무용에 접근하는데 있어서, 첫째는 니체의 미학사상을 토대로 현대무용의 미학과 발전을 알아본다. 둘째는 그레이엄 무용의 근원적 가치와 의미를 동작원리와 작품세계를 통해 고찰한다. 셋째는 마사 그레이엄 무용미학에 미친 니체의 영향을 밝힌다. 이 연구는 니체를 통해 창조적 자기표현과 자기완성의 과정으로서의 그레이엄의 춤을 사유하도록 한다. 삶과 창조 그리고 숭고의 니체미학이 자연성, 자유, 몸을 근간으로 마사 그레이엄에 미친 영향은 다음과 같이 정리될 수 있다. 신화 등의 소재를 재해석하는 창작활동에 의해 그레이엄은 자신의 세계관과 가치관을 표현하였을 뿐만 아니라 자신의 삶을 개척해 나아갔다. 또한 삶과 예술을 몸의 살아있는 경험으로 미학화 한다. 즉 언어로서 끌어 올리는 데에는 한계를 지닌 감각적인 근본적 세계를 그레이엄은 동작언어로서 재현해내고 창조한다. 그레이엄은 무용을 통해 디오니소스적 이념 자체의 내용으로서의 도취와 인간의 정열의 확대를 실천한다. 그레이엄의 신체 개념은 인간의 내면을 드러내고 표현하는 방법과 기술 그리고 내면의 내용에 적절한 구조의 발굴 등을 모두 포함하며, 단순한 전달의 도구적 기능에서 더 나아가 기술의 습득에 의해 내부로부터 자유로워질 수 있고 자기 자신에 대한 신념을 키워주는 신체, 즉 가벼운 춤의 상태를 이룬 짜라투스트라의 신체와 상통한다. The thesis discusses Martha Graham`s Dance influenced by philosophy of Nietzsche. According to Nietzsche, dance is a symbolic concept used for his philosophical logic. The dance symbolize freedom, eternity, the Dionysiac concepts. The dancer`s body not only is considered to be important as the real and experiential, but also is a theme of Nietzsche`s thought. The thesis consists of three parts. First one is to recognize the aesthetic of modern dance based on the philosophy of Nietzsche. The second one is to explore the artistic value and significance of Martha Graham dances. The third one is to find out the influential elements of Nietzsche`s thought appeared in Martha Graham dances. Exploring her subjective life, she communicates her own thought and aesthetic judgement. She creates movement vocabularies in her dance to which the verbal words are limited in expressive approach. Also she approaches to Dionysiac intoxication by dancing. Dancer`s body as instrument for Graham dance combines expressive techniques, method, function, formal structure and internal contents, which imply physical freedom by acquisition of proper techniques. The mission of human being lies in the completion of the self. For Nietzsche dance is such an accomplishment. The influence of aesthetics of Nietzsche can be found in the creative process and dancer`s body, also in the artistic life and the grace which is achieved after such a procedure.

현대무용의 철학사조

장정윤 ( Chung Yoon Chang ) 대한무용학회 1995 대한무용학회논문집 Vol.18 No.-

무용에서의 정의의 개념에 관한 연구

장정윤 ( Chung Yoon Chang ) 대한무용학회 2010 대한무용학회논문집 Vol.62 No.-

Justice in relation with art expresses the condition in which every person has the absolute potential to show his own personality, talent, and ability. The discussion of the relation between arts and justice in this essay starts from understanding both abstract and concrete concepts of justice dealt in Aristotle`s Politics, Nichomachian Ethics and Poetics. The concrete form of realizing justice through art is virtue, and the concrete virtue can be found in art, which realizes catharsis and justice. The realization of justice is placed in virtue in terms of art, criticizing right and wrong of an artistic act. However, Aristotle`s concept of realizing justice refers to good in human being prior to art. An artistic act with right attitude means an act that follows the disposition which asks the right and is done in law-abiding spirit and just attitude for the good of the national community. The purpose of this essay is to provide the fundamental understanding about what human being pursues and the ideology of art with regard to justice. In this essay I discuss three points. First, Aristotle`s concept of justice which fundamentally is operative in art. Secondly I discuss interrelation of dance and justice and in this context discusses `resistance`, `mobilization`, `social movement` and `diversity` of dance aspects. Lastly I discuss contemporary practices of the 1960s` Judson dance activities which is regarded as revolutionary activity, challenged to the prevailing social ideology, and its relationship with social movement is considered. The practices are examined by the themes of freedom, equality and liberation of the body through their choreographic works.

인문 , 사회과학논문 : 밤의 여행 ( Night Journey ) 에 관한 해석학적 접근

장정윤(Chung Yoon Chang) 대한무용학회 2001 대한무용학회논문집 Vol.31 No.-

예비유아교사의 수학에 대한 이미지

장정윤(Chang Jung Yoon) 한국육아지원학회 2013 육아지원연구 Vol.8 No.2

본 연구는 예비유아교사들이 ‘수학’이라는 과목에 대해 갖고 있는 이미지를 분석하는 것이 목적이다. 연구대상은 3년제 대학 유아교육학과 3학년 학생 58명이다. 자료 수집을 위해 수학에 대한 이미지 그 리기와 설명하기를 학기말에 실시하였으며, 수집된 자료는 내용분석을 실시하였다. 분석결과는 크게 수학에 대한 과거의 이미지, 과거의 이미지 형성에 영향을 미친 요인, 수학에 대한 현재의 이미지로 나 뉘었다. 연구결과 첫째, 예비유아교사들의 수학에 대한 과거의 이미지는 수학을 하는 딱딱하고 고리타 분한 사람, 재미없고 두려운 수학수업, 어지럽고 어려운 수학과목에 대한 이미지로 나타났다. 둘째, 예 비유아교사들의 수학에 대한 과거의 이미지 형성에 영향을 미친 요인으로는 반복된 성취와 좌절의 경 험, 수학선생님에 대한 긍정적․부정적 기억, 노력을 해도 점수가 오르지 않았던 개인적 경험인 것으로 나타났다. 마지막으로 예비유아교사들의 수학에 대한 현재의 이미지는 수학을 향한 노력과 의지, 수학 의 개념에 대한 인식, 수학의 일상성 발견에 대한 이미지로 나타났다. 이와 같은 연구결과는 예비유아 교사들의 수학에 대한 태도와 이에 따른 수학 교수효능감을 완화시키고 유아수학교육의 바람직한 교수 학습방법을 준비하기 위한 교사교육 방향을 제공할 수 있을 것이다. This study aims to examine how early childhood pre-service teachers perceive images of mathematics. For this study, 58 early childhood pre-service teachers drew a picture and explained their first and present images of mathematics through their own drawings. Because this study aimed to identify pre-service teachers’ implicit perception of the image, various drawing techniques (e. g., free drawings, prose, and speech bubble) and expressive methods (e.g., realistic, metaphorical and comparative) were adopted. The collected data were analyzed using contents analysis. Specific results of each part are as follows. First, The previous images of mathematics pre-service educators perceived were described as a person who is very stuffy and old-fashioned. Other images were a classroom hour which was very boring and scary when they were in middle school or high school, and mathematics as a dizzy and difficult subject. Second, The primary influences on early childhood pre-service teachers’ previous images of mathematics were described as repeated achievements and frustrations, positive or negative memory of their math teachers, and their personal experience failing in exam despite their efforts. Third, The present images of mathematics that pre-service teachers perceived were described as their strong endeavor and willingness to study mathematics. There were images of their desire to apply what they learned from lecture to a near future. Images of their perceptions about mathematical concepts (counting and calculating, geometry, patterns, measurement, and data analysis) and discovery of mathematics in everyday life were identified. This study can provide directions for educating early childhood pre-service teachers both relieving their mathematics anxiety and improving their mathematics efficacy.

미국의 자기 파괴적 남성다움의 가능성과 한계: 척 팔라닉의 『파이트 클럽』을 중심으로

장정윤 ( Jung Yoon Chang ) 한국현대영미소설학회 2013 현대영미소설 Vol.20 No.1

This study explores not only the subjective violence created by an American middle-class white man, but also the objective violence that causes the subjective violence in Chuck Palahniuk`s Fight Club. Although he is a safe man in society, the unnamed narrator feels a sense of emptiness inside, so much so that he suffers from melancholia and insomnia. The main reason for his depression is that he does not have a father who can teach him how to compete with other people and how to maintain morality within society in order to become a typical model of American manhood. This is why he creates Tyler Durden, his fictional alter ego, and organizes Fight club in which men fight each other in an effort to establish a feeling of power within the world. Tyler exists as a father figure for the unnamed narrator, and as an ideal subject who can criticize the problem of the late capitalized society and build a new, self-destructive manhood that helps men break their limitations. Tyler uses fighting, subjective violence, to encourage the men to explore their own possibilities and to bond with each other, and then points out the true nature of the objective violence within the capitalist society. Tyler, however, threatens to take over the unnamed narrator`s body and acts like a tyrant. Moreover he ignores the sacrifices made by the other members in order to maintain Project Mayhem, the organization that succeeds Fight Club. Thus, the unnamed narrator begins to doubt Project Mayhem`s validity and realizes that it excludes the “other,” such as Marla Singer who symbolizes the socially weak. In other words, he finally understands that Tyler does not, in fact, establish a balance of power needed to resist the systematic violence that interferes with the healthy and productive lives of the subject within the capitalist society. Therefore, he cannot help but confine himself to a psychiatric hospital in order to be free from Tyler.

‘연민’의 감정 가르치기: 「제비뽑기 」 와 「오멜라스를 떠나는 사람들 」

장정윤(Jungyoon Chang) 한국영미문학교육학회 2019 영미문학교육 Vol.23 No.3

This study explores how to teach the relationship between compassion and violence, studying Shirley Jackson’s “The Lottery” and Urusula Le Guin’s “The Ones Who Walk Away from Omelas.” These two short stories reveal the selfish nature of humans to keep their own safety and well-being and to ignore the injustice of violence that kills the person with the stone in “The Lottery” and confines the child in the basement in “The Ones Who Walk Away from Omelas.” First, while reading these stories, students should understand the characteristics of the subjective and objective violence that Slavoj Žižek refers to: to study how people perpetrate subjective violence according to their desire to be safe in society and to figure out how objective violence manipulates people to inflict subjective violence on the weak. Second, students will recognize that these two stories lack a feeling of compassion and a feeling of suffering that arises from human being’s vulnerability, the perception that we are not free from violence, and that we can always be in a position of weakness like Tessie Hutchinson in “The Lottery” and the child in “The Ones Who Walk Away from Omelas.” In other words, students have to understand we cannot separate ourselves from the weak who suffer from violence caused by human selfishness and should think about safe spaces for the weak because the place that these members of society feel comfortable is truly good for our place. Therefore, this study emphasizes how to develop compassion through reading iterature.