http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
장시혁,류종석,김재범,이풍연,권무식 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.3 No.2
PU.1 is a transcription factor which binds to a DNA motif, 5'-GAGGAA-3' (PU Box). Its expression is restricted to macrophage and B cell in mammal. Activation of the PU.1 transcription factor seems to be accomplished by the phosphorylation of specific serine residue(s) of PU.1 the polypeptide. In an attempt to elucidate the phosphorylation site(s), a PU1 mutant clone named pJKS142A was constructed as follows. Two nucleotides coding for the 142th amino acid [serine(AGC)] of the PU1 polypeptide, "Adenine & Guanine", were substituted by "Guanine & Cytosine" by employing splicing by overlap extenion (SOE) methods. The mutant PU.1 cDNA, PU.S142A, was ligated into HindⅢ/XbaI-cut pBluescript KS+, and then transformed into E. coli XL-1 Blue to generate pJKS142A. Recombinant plasmid DNA, pJKS142A was isolated and the DNA sequence was determined by the method of Sanger to confirm the site directed mutagenesis of PU.1 eDNA. The pJKS142A will be instrumental in evaluating a plusible phosphorylation site(s) of PU.1.
장시혁,지성남,정봉철,남임우 대한설비공학회 2005 대한설비공학회 강연회 및 기타간행물 Vol.- No.-
최근 인터넷 망을 통해 원격지에서 기기 제어 및 감시를 가능한 시스템 개발이 활발하다. 인터넷을 통해 제어할 경우 현장에서 동작중인 설비들에 대한 정보를 원격지에서 관리 감독이 용이하여 신속하게 대처할 수 있게 된다. 그리고 인터넷의 특성상 중요 관리자가 원거리로 이동하게 되는 경우에도 인터넷을 통해 접속하여 현장 상황 및 기기의 동작 상태를 쉽게 점검할 수 있어 관리 비용을 절감할 수 있을 것으로 기대되며, 소비자 만족도를 높이고, 제품의 A/S 비용을 절감할 수 있는 효과를 가져 올 수 있다. 또한 하나의 현장에 여러 대의 냉난방기가 설치될 경우 그 현장의 관리실에서도 전체 냉난방기의 원격 제어 및 감시가 가능하기 때문에 비교적 저가의 비용으로 인터넷을 이용한 빌딩 내 중앙 감시 시스템의 구축도 가능하며, 중앙 감시 센터의 메인 서버에서는 전국에 설치된 기기의 데이터를 저장할 수 있다. 그리고 메인 서버에서는 필요에 따라 CRM(Customer Relationship Management) 데이터베이스와도 연동 혹은 단독 데이터베이스를 이용하여 고객관리가 좀 더 용이하게 될 수 있다. 본 논문에서는 소형 흡수식 냉난방기에 인터넷을 이용한 원격 제어 시스템을 구축하여 제품의 A/S가 발생하였을 때 엔지니어가 직접 방문하지 않더라도 원격지에 있는 메인 서버에서 인터넷을 이용하여 제품점검이 가능한 시스템에 관한 연구 내용을 소개하고자 한다.
손발톱하 사구 종양에서 초음파를 이용한 진단 및 수술 전 평가
장시혁 ( Sihyeok Jang ),조성문 ( Seongmoon Jo ),박송연 ( Song Youn Park ),윤현선 ( Hyun Sun Yoon ),조소연 ( Soyun Cho ),박현선 ( Hyun Sun Park ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.5
Subungual glomus tumors are benign neoplasms that arise from the neuromyoarterial apparatus. They present with various clinical symptoms such as localized pain, tenderness, and sensitivity to temperature change and can be palpated as a nodule or mass on physical examination. Pressure erosion can be seen at adjacent bones on radiography. However, in most cases, the tumors are too small to be inspected and located under the nail plate, which makes correct diagnosis and complete excision very difficult. Incomplete removal can cause recurrence or deformity to the residual nail, whereas extensive removal can cause trauma or deformity to the nail plate. Thus, correct differential diagnosis and preoperative evaluation of the location and extent of the tumor are very important. Here, we report 2 cases that were diagnosed and preoperatively evaluated using ultrasound. (Korean J Dermatol 2014;52(5):341∼344)
Methyl-Aminolevulinate를 이용한 광역동치료로 치료한 단발성 균상식육종
장시혁 ( Sihyeok Jang ),황은정 ( Eun Jung Hwang ),류형호 ( Hyeong Ho Ryu ),조광현 ( Kwang Hyun Cho ),조성진 ( Seong Jin Jo ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.1
Various treatment modalities are available for mycosis fungoides including topical steroids, topical chemotherapy,phototherapy, and spot radiation therapy. However, these modalities do not always result in optimal effects, withefficacy depending on lesion size, number, and location. Photodynamic therapy (PDT) is a recently introducedtherapeutic modality that proved effective in patients with unilesional mycosis fungoides. A 58-year-old womanpresented with a seven-year history of a pruritic erythematous scaly patch on her right thigh. Through skin biopsy,we verified the lesion as mycosis fungoides. The lesion did not respond well to a topical steroid. We opted fortopical PDT with methyl-aminolevulinate (MAL). MAL cream was applied for 4 hours following irradiation with ared light. Four sessions were administered, separated by five weeks. The lesion clinically improved after treatmentwithout severe side effects. PDT using MAL could be considered an effective and tolerable treatment for mycosisfungoides. (Korean J Dermatol 2015;53(1):58∼61)
한국인에서 일광노출과 자외선차단제에 대한 인식과 사용 행태 연구
장시혁 ( Si Hyeok Jang ),박현선 ( Hyun Sun Park ),조소연 ( So Yun Cho ),윤현선 ( Hyun Sun Yoon ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.1
Background: Although sunscreen is used as a primary strategy for the prevention of sunburn, photoaging, and skincancer, few people regularly use sunscreen. Objective: To investigate awareness regarding the effects of sunlight, the extent of sun exposure, and sunscreen usebehaviors in Korean subjects. Methods: A questionnaire was administered to 467 adult patients who visited the Dermatology Department at SeoulNational University Boramae Hospital. The questionnaire covered demographic characteristics, causes of wrinkles,sunspots, and skin cancer, awareness of the harmful effects of sun exposure, perceived and actual extent of sunexposure, and the use of sun-protective methods including sunscreen. Results: Sun exposure was selected as the major cause of age spots (60.6%), skin cancer (60.9%), and wrinkles(25.9%). Respondents were likely to underestimate the extent of sun exposure. On average, quite a few respondentsstated that they were exposed to sunlight for more than one hour per day (22.7% on weekdays, 52.4% onweekends). However, only 9.4% of respondents thought that their sun exposure was problematic and 62.7% ofrespondents considered moderate sunlight exposure healthy. Respondents`` sun-protective behaviors were inadequate:only 29.8% used sunscreen regularly, and 16.5% have never used sunscreen. SPF was the most important factor inchoosing sunscreen, and 83.3% used a sunscreen with a labeled SPF over 30. By contrast, only 34.6% ofrespondents used PA+++ sunscreen. Conclusion: Despite fairly good knowledge regarding the harmful effects of sunlight, subjects underestimated therisks of their sun exposure and sun-protective behaviors were suboptimal. Education on the risk of UV exposure andeffects of sunscreen is still needed. (Korean J Dermatol 2015;53(1):16∼22)