http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Trimethyltin에 의한 랫드 해마의 신경세포 사멸과 iNOS의 연관성
장석원,최성영,박창남,안미정,신태균,김승준,Jang, Sukwon,Choi, Sungyoung,Park, Changnam,Ahn, Meejung,Shin, Taekyun,Kim, Seungjoon 대한수의학회 2011 大韓獸醫學會誌 Vol.51 No.3
Trimethyltin chloride (TMT) has been used as a neurotoxin for inducing brain dysfunction and neuronal death. Neuronal death in the hippocampus by TMT may generate excessive nitric oxide, but there are few studies about nitric oxide synthase enzyme involved in the synthesis of nitric oxide. The purpose of present study is to analyze the TMT toxicity in each region of rat hippocampus. To evaluate the involvement of nitric oxide, we analyzed the effects of aminoguanidine known as a selective inhibitor for inducible nitric oxide synthase on behavioral changes and the hippocampus of rat by TMT toxicity. 6-week-old male Sprague-Dawley rats were administered with a single dose of TMT (8 mg/kg b.w., i.p.) and the control group was similarly administered with distilled water. TMT + aminoguanidine-treated groups were administered with aminoguanidine (10 mg/kg or 100 mg/kg b.w., i.p.) for 3 days prior to TMT injection. The rats were sacrificed 2 days after TMT administration. In the TMT-treated group, a number of cell losses were seen in CA1, CA3 and the dentate gyrus. In the TMT + aminoguanidine-treated group, neuronal death was seen in CA1 and CA3, but reduced in the dentate gyrus compared to the TMT-treated group. Western blot analysis showed that cleaved caspase-3 expression was increased in the TMT-treated group compared to the control group. However, the expression significantly declined in the TMT + aminoguanidine-treated group. The present findings suggest that inducible nitric oxide synthase is involved in neuronal death induced by TMT.
장석원,이태규,이진승,Jang, Sukwon,Lee, Taegyoo,Lee, Jinseung 한국군사과학기술학회 2015 한국군사과학기술학회지 Vol.18 No.1
In this paper, we have described target positioning of automatic survey system. Target positioning error analysis shows target positioning errors are mainly dependent on the vertical angle of the triangle configured by target and two measurement points. Suggested target positioning error formula are confirmed by simulation using the Gaussian distribution.
DTW와 Kalman Filter를 결합한 비행표적의 광학추적 방법
장석원 ( Sukwon Jang ) 한국항행학회 2021 韓國航行學會論文誌 Vol.25 No.3
EOTS(electro-optical tracking system)는 유도무기의 성능 평가를 위해 유도무기를 추적하여 영상을 획득하는데 활용되고 있다. 유도무기에 대한 추적을 잃어버렸을 경우 유도무기가 매우 빠르게 비행하기 때문에 운용자가 이를 다시 포착하는 것은 거의 불가능하다. 레이더나 텔레메트리 데이터를 활용하여 재 포착 하는 방법이 활용되고 있으나 데이터를 실시간으로 수신할 수 있는 통신망의 설치가 수반되어야하기 때문에 장소에 대한 제약이 따른다. 하지만 유도무기 비행시험 수행 시 계산되는 예상 궤적은 실시간으로 수신할 필요 없이 저장해두었다가 사용할 수 있기 때문에 통신망 설비와 관계없이 활용이 가능하다. 본 논문에서는 미리 알고 있는 비행체의 예상 궤적을 활용하여 비행체를 잃어버렸을 시 비행체의 위치를 예상하는 방법을 제안한다. DTW (dynamic time warping)를 통해 예상궤적과 추적궤적을 비교하여 비행체의 각속도를 추정하고 이를 Kalman Filter의 보정단계에서 관측 값으로 활용하여 비행체의 다음 상태를 예측한다. 제안한 방법의 타당성을 실제 비행체 궤적에 적용하여 검증하였다. EOTS(Electro-Optical Tracking System) is utilized in acquiring visual information to assess a guided missile’s performance. As the missile travels so fast, it is almost impossible for operator to re-capture the lost target. The RADAR or telemetry data are used to re-capture the lost target however facilities to receive real time data is required, which constrains selection of tracking site. Unlike aforementioned data, pre-calculated nominal trajectory can be used without communication facility. This paper proposes a method to predict lost target’s state by employing nominal trajectory. Firstly, observed trajectory and nominal trajectory are compared using DTW and current target’s state is predicted. The predicted state is used as observation in Kalman filter’s correction phase to predict target’s next state. The plausibility of the proposed method is verified by applying on actual missile trajectory.
점화안전장치 적용을 위한 저임계가속도 MEMS 가속도 스위치 설계
황정기(Jeongki Hwang),장석원(Sukwon Jang),박치현(Chi-Hyeun Park),이충일(Chung-Il Lee),장승교(Seung-Gyo Jang),김용권(Yong-Kweon Kim) 한국추진공학회 2015 한국추진공학회 학술대회논문집 Vol.2015 No.11
본 논문은 10 g 수준의 낮은 임계가속도를 가진 MEMS 가속도 스위치의 설계에 대해 보고한다. 낮은 스프링 상수, 무거운 관성질량, 그리고 좁은 초기 간격의 구현은 MEMS 가속도 스위치의 저임계가속도 특성 구현을 위한 필수 요소이다. 본 설계에서는 Serpentine 구조의 스프링을 사용하였으며 설계된 스프링 상수, 초기 간격, 그리고 관성질량은 은 각각 14.45 N/m, 3 μm, 4.4×10<SUP>-7</SUP> kg이었다. 이에 따른 임계가속도 값은 10.05 g로 계산되었다. This paper reports on the design of the MEMS acceleration switch having low threshold as low as 10 g. Low spring constant, heavy proof-mass, and narrow initial switching gap are critical factors to achieve low-g characteristic of MEMS accelerations switch. Serpentine type springs were designed to support proof-mass. The spring constant, initial switching gap, and the weight of proof-mass were designed as 14.45 N/m, 3 μm, and 4.4×10<SUP>-7</SUP> kg respectively. The corresponding threshold acceleration was calculated to be 10.05 g.