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인터뷰 - 첨단 물류기기 표준화의 선구자 '생수이동랙 개발'
이홍기,Lee, Hong-Gi 한국파렛트컨테이너협회 2009 파렛트 뉴스 Vol.53 No.-
본 인터뷰 기사는 지난 2008년 12월 30일 월간 굿뉴스피플에 실린 내용으로 최근생수물류과정에 문제를 제기하여 '생수이동랙 개발 에 힘을 실어온 (주)골드라인의 이홍기 회장의 인터뷰 내용이다.
Formulation of a Extended Release Tablet Containing Dexibuprofen
이홍기,지문혁,김용일,박은석,우종수 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.12
Dexibuprofen, or S(+)-ibuprofen, is the pharmacologically effective enantiomer of racemic ibuprofen. Since dexibuprofen has a low melting point, the amorphous form having a high melting point was prepared with the fused solid dispersion method. With the fused solid dispersion of dexibuprofen, immediate release tablets, extended release tablets, and dual release tablets were compressed and their dissolution profiles compared. The dissolution profiles of the extended release and the dual release tablet depended on the amount of used release modulators (PEO 5,000,000). The release profiles of extended release tablets and extended release part of dual release tablets were well fitted to zero-order release model. The correlation coefficient ranged from 0.982 to 0.995. A pharmacokinetic evaluation where healthy volunteers took tablets of DRT-1 (300 mg) once and the reference drug, two tablets of conventional immediate release tablet (Daxfen, 300 mg), with a 6-h interval between them was studied. The 90% confidence interval for the ratio of the logarithmically transformed AUC (0-24 h), Cmax (0-6 h), and Cmax (6-24 h) values of the dual release tablet compared to those of the conventional immediate release tablet were calculated to be between 0.9176 and 1.0007, 0.9240 and 1.1968, and 0.8713 and 1.1414, respectively. When the immediate release tablet was taken two times with a six hour interval between doses it showed a bioequivalent effect to taking the dual release tablet once within 12 h. The Cmax was reached due to the rapid absorption of the immediate release portion of the dual release tablet and the AUC was maintained due to continuous absorption of the extended release portion.
산림치유 프로그램 참여자의 숙박 경험 여부에 따른 인식 및 선호도 분석
이홍기,이돈각,김동준 한국산림휴양복지학회 2023 한국산림휴양학회지 Vol.27 No.3
본 연구는 산림치유 활성화 방안을 마련하고자 산림치유 프로그램 참여자를 대상으로 설문조사를 실시하여, SPSS 19.0로 분석하였다. 본 연구는 숙박 프로그램 경험자와 무경험자를 중심으로 분석하였으며 두 집단 간 차이점을 분석하기 위해 Chi-sqare test (χ2)를 사용하여 분석한 결과, 산림치유 프로그램 참여자들의 산림치유 재 참여율은 34.7%, 참여 시간은 4시간 이하가 63.5%, 일회성 참여자가 90.1%로 나타났다. 그러나 응답자의 40.2%가 1박 2일 ~ 2박 3일 등 숙박 프로그램을 가장 선호하였으며, 63.4%가 카페 등 편의시설 이용을 희망하였고, 일회기보다 여러 회기로 구성된 프로그램 참여를 선호하는 응답률도 40.6%나 되었다. 산림치유 참여목적은 주로 스트레스 해소 및 심리적 안정이었다. 산림치유 프로그램 참여자들의 75.3%가 숙박시설을 선호하며, 76.5%가 산림문화·휴양·관광 ·숙박 등에 대하여 단지 내 조성을 요구하는 것으로 나타나 치유의 숲 센터 내 숙박시설이나 기타 편의시설 설치 등에 관한 대안의 논의가 적극적으로 필요하다. 앞으로 산림치유 활성화를 위해서는 산림치유 참여자의 인식 및 선호도 등에 관한 연구 결과를 반영하여 대안에 대한 지속적인 검토가 이루어져야 할 것으로 판단된다. In this study, in order to prepare a plan to activate forest healing, a survey was conducted on participants in the forest healing program and analyzed using SPSS 19.0. This study analyzed the difference between lodgment experience group and inexperienced gtroup and Chi-square test (χ2) was used. As a result of the analysis, the re-participation rate of forest healing program participants was 34.7%, the participation time less than 4 hours was 63.5%, and the one-time participation was 90.1%. However, 40.2% of the respondents preferred lodgment programs such as 2 days and 1 night to 3 days and 2 nights, and 63.4% wanted to use convenience facilities such as cafeterias. And 40.6% of respondents preferred to participate in programs consisting of multiple sessions to one session. The purpose of participating in forest healing program was mainly stress relief and psychological stability. 75.3% of participants in the forest healing program preferred lodging facilities, As 76.5% of participants demanded the creation of complexes for forest culture, recreation, tourism, lodging, etc., active discussions on alternatives such as installation of accommodation facilities or other convenience facilities in the forest healing center are needed. In order to activate forest healing in the future, it is judged that continuous reviews for the alternatives should be taken by reflecting the research results on the perception and preference of participants in forest healing.