한국판 저장행동평가척도의 표준화 연구

이혜민,장진구,송후림,이수영,홍민하,김세주,김찬형,Lee, Hye Min,Chang, Jhin Goo,Song, Hoo Rim,Lee, Soo Young,Hong, Minha,Kim, Se Joo,Kim, Chan-Hyung 대한불안의학회 2021 대한불안의학회지 Vol.17 No.2

Objective : The Hoarding Rating Scale-Self-Report (HRS-SR) is a five-item scale that simply assesses the hoarding symptoms. We evaluated the factor structure, reliability, and validity of the Korean version of the HRS-SR (HRS-SR-K). Methods : A total of 144 individuals completed the self-administered questionnaires including HRS-SR-K, Obsessive-Compulsive Inventory-Revised-Korean version (OCI-R-K), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Psychometric properties of the HRS-SR-K were analyzed. Results : The Cronbach's α value for internal consistency of the HRS-SR-K was excellent (Cronbach's α=0.84). The construct validity was analyzed on the basis of principal component analysis and one-factor structure of the original scale was maintained. The HRS-SR-K total score and each item scores were more strongly correlated with the hoarding subscale score in OCI-R-K (convergent validity, r=0.71, p<0.01) than the corresponding scores of nonspecific depression or anxiety measures (discriminant validity). Conclusion : The HRS-SR-K is a simple and reliable self-report scale for examining the severity of hoarding symptoms.

회음 천공지 기저 도서형 피판을 이용한 회음부 재건

이혜민,김정태,황원중,Lee, Hae Min,Kim, Jeong Tae,Hwang, Weon Joong 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.1

Perineal area is composed of compact structures of urogenital organs and anus requiring a more sophisticated selection of flap and reconstruction. For achieving better outcome then conventional flap surgery, we use the perineal perforator based island flap for its reconstruction. After locating the perforator by Doppler, the flaps were designed according to the defect or expected vaginal orifice. The flaps were elevated bilaterally as island pattern. Finally defect or neovagina was reconstructed with inconspicious linear scar hidden in the inguinal crease. Five cases were performed with the perineal perforator based island flap. There were 3 cases of vulvar cancer, 1 case of transsexualism, and 1 case of ambiguous genitalia because of congenital adrenal hyperplasia. Operative results were satisfactory with good contouring and less prominent donor scar, when they were compared with other flap reconstructions such as latissimus dorsi perforator flap, groin flap, gracilis myocutaneous flap etc. The perineal perforator based island flap is highly recommended with the advantages of easy flap elevation, good rotation arc, and appropriate flap thickness for contouring. Compared with other conventional flaps, it can be selected as a good option for moderate defect of perineal area.

폐외 결핵에서 전혈 인터페론 감마 측정법의 진단적 유용성

이혜민 ( Hye Min Lee ),조성근 ( Sung Gun Cho ),강형구 ( Hyung Koo Kang ),박성운 ( Sung Woon Park ),이병욱 ( Byung Ook Lee ),이재희 ( Jae Hee Lee ),전은주 ( Eun Ju Jeon ),최재철 ( Jae Chol Choi ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.4

Background: The whole-blood interferon-gamma release assay (QuantiFERON-TB Gold [QFT-G]: Cellestis, Carnegie, Victoria, Australia) has been studied primarily for the use of diagnosing active pulmonary tuberculosis (TB) or latent TB. In the present study, the usefulness of QFT-G was evaluated for the diagnosis of extra-pulmonary tuberculosis (EP-TB). Methods: From June 2006 to February 2009, we evaluated the usefulness of QFT-G in patients (n=65) suspected with EP-TB, retrospectively. The diagnostic sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the QFT-G assay were analyzed. Results: EP-TB was diagnosed in 33 (51%) participants. The overall sensitivity, specificity, PPV, and NPV of the QFT-G assay for EP-TB were 78%, 79%, 81%, and 77%, respectively. Of the 33 with EP-TB, 14 (42%) were diagnosed with TB pleurisy, 7 (21%) with TB lymphadenitis, 7 (21%) with intestinal TB, and 5 (15%) with EP-TB in other sites. In subgroup analyses according by site of infection, the QFT-G showed 86% sensitivity, 64% specificity, and 78% NPV in TB pleurisy. On the other hand, the sensitivity, specificity, and NPV of the assay were 71%, 83% and 71%, respectively in TB lymphadenitis, and 86%, 100% and 88%, respectively in intestinal TB. Among the patients with suspected alternative site EP-TB, the sensitivity, specificity, and NPV of the assay were 50%, 80% and 67%, respectively. Conclusion: The QFT-G assay showed moderate diagnostic accuracy in EP-TB. However, negative QFT-G assay does not exclude EP-TB because of the low NPV of this assay.

당뇨를 동반한 지속외래복막투석 환자에서 발생한 Neisseria sicca 복막염 1예

이혜민 ( Hyae Min Lee ),양인호 ( In Ho Yang ),이선희 ( Sun Hee Lee ),김선혜 ( Seon Hye Kim ),정다운 ( Da Wun Jeong ),정경환 ( Kyung Hwan Jeong ),이상호 ( Sang Ho Lee ),이태원 ( Tae Won Lee ),임천규 ( Chun Gyoo Ihm ),문주영 ( Ju Yo 전북대학교 의과학연구소 2014 全北醫大論文集 Vol.38 No.2

Neisseria sicca is a Gram-negative diplococcus found in the human oral mucosa and upper respiratory tract. Although colonization generally does not result in severe infection, some cases of infection have been reported, particularly in immunocompromised individuals. However, Neisseria sicca has not been reported as a pathogen of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis in Korea. Here we describe a case of CAPD-related peritonitis due to Neisseria sicca in a patient with poorly controlled diabetes mellitus undergoing peritoneal dialysis.

한국산 꿀벌에서 Deformed Wing Virus의 발견과 Real-Time PCR 검출법의 확립

이혜민(Hye-Min Lee),이도부(Do-Bu Lee),한상훈(Sang-Hoon Han),이명렬(Myeong-Lyeol Lee),임윤규(Yoon-Kyu Lim),윤병수(Byoung-Su Yoon) 한국양봉학회 2005 韓國養蜂學會誌 Vol.20 No.2

임상적 아형 및 연령에 따른 선상태선의 임상 및 조직병리학적 고찰

이혜민 ( Hye Min Lee ),정경은 ( Kyung Eun Jung ),이혜경 ( Hye Kyung Lee ),구대원 ( Dae Won Koo ),이중선 ( Joong Sun Lee ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.9

Background: Lichen striatus is an uncommon, self-limiting, linear inflammatory disease occurring along the lines of Blaschko, mainly affecting children, and is diagnosed by clinical history and histopathological study of typical lesions. However, various aspects of the histopathologic findings have not yet been studied sufficiently. Objective: The aim of this study was to investigate the clinical and histopathologic characteristics of lichen striatus in Korea, according to age and clinical subtype. Methods: This retrospective study on lichen striatus was performed at our center; clinical and histopathologic findings from 32 patients were evaluated. Results: In all, 22 children and 10 adults were included. The lesions were predominantly distributed on the extremities (78.1%), including those that showed multiregional involvement. Twenty-four patients had erythematous papular lichen striatus (75%), and eight had hypopigmented macular type lesions (25%). All cases of hypopigmented macular subtypes had occurred in children. The histopathologic features of lichen striatus included basal vacuolar degeneration (93.3%), hyperkeratosis (83.3%), spongiosis (63.3%), and exocytosis of lymphocytes (63.3%) in the epidermis. Superficial and deep perivascular lymphocytic inflammatory infiltration (96.7%), lichenoid lymphohistiocytic infiltration (76.7%), and periappendageal involvement (53.3%) in the dermis were also observed. Papular lesions showed greater spongiosis, exocytosis, dyskeratosis, and vacuolar degeneration than hypopigmented lesions. Increased dyskeratosis and pigmentary incontinence as well as more severe lichenoid infiltration were observed in the adults. Conclusion: This study provides the first national data about the clinical and histopathologic characteristics of lichen striatus in adults and children. Some of the clinical and histopathologic characteristics differed according to the age group as well as clinical subtype. (Korean J Dermatol 2014;52(9):622∼630)

Bevacizumab 사용 후 발생한 심한 허혈성 전대장염에서 대증적 요법으로 치료된

이하니 ( Ha Ni Lee ),이명아 ( Myung Ah Lee ),김상우 ( Sang Woo Kim ),임예지 ( Ye Jee Lim ),이화영 ( Hwa Young Lee ),이혜민 ( Hae Min Lee ),원혜성 ( Hye Sung Won ),전상훈 ( Sang Hoon Chun ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.1

Bevacizumab (Avastin(R)) is a monoclonal antibody against the vascular endothelial growth factor (VEGF) receptor that increases the overall survival rate when added to standard chemotherapy regimens in patients with metastatic colorectal cancer. The known toxicities of bevacizumab are hypertension, proteinuria, wound healing complications, arterial thrombosis, bleeding, and gastrointestinal complications. Especially ischemic colitis can rapidly develop into bowel perforation, so an emergency operation often is needed. Recently, a 65-year-old male patient developed ischemic pancolitis after FOLFOX (85 mg/m2 Oxaliplatin, d1; 200 mg/m2 Leucovorin, d1; 400 mg/m2 5-FU iv bolus, d1-2; and 600 mg/m2 5-FU, d1-2, every two wk) and Bevacizumab combination chemotherapy was administered. However, he recovered after early conservative care without surgery. We report this case with a review of literature. (Korean J Gastroenterol 2011;58:42-46)

혈구탐식성 림프조직구증이 동반된 성인형스틸병 1예

김광열 ( Kwang Yeol Kim ),최지영 ( Ji Young Choi ),이민혜 ( Min Hye Lee ),이정록 ( Jung Lok Lee ),양인호 ( In Ho Yang ),이혜민 ( Hyae Min Lee ),조영학 ( Young Hak Cho ),이유호 ( Yu Ho Lee ),이선희 ( Sun Hee Lee ),김동희 ( Dong Hee 전북대학교 의과학연구소 2014 全北醫大論文集 Vol.38 No.1

혈구탐식성 림프조직구증이 동반된 성인 형스틸병은 드물지만 치명적인 결과를 가져올 수 있기 때문에 조기에 병을 진단하고 일찍 적절한 치료를 시작하는 것이 중요하며 저자들은 골수천자 검사로 혈구탐식성 림프조직구증이 동반된 성인형스틸병 예를 경험하였기에 이에 문헌 고찰과 함께 보고하는 바이다. Adult-onset Still`s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. It is characterized by fever, skin rash, arthralgia, sore throat, hepatosplenomegaly, lymphadenopathy, leukocytosis, liver enzyme elevation, and high serum level of ferritin. Hemophagocyticlymphohistiocytosis is a rarerheumatic disease of life-threatening. Particularly, concomitant hemophagocyticlymphohistiocytosiswith AOSD could induce a fatal outcome. Thus it is important diagnos early and starttreatment. Here, we report a case of AOSD with concomitant hemophagocyticlymphohistiocytosis.

연구 논문 : 15세기 말 잉글랜드와 부르고뉴의 인적, 문화적 교류 -책과 인쇄 문화를 중심으로-

이혜민 ( Hye Min Lee ) 영국사학회 2011 영국연구 Vol.25 No.-

이 논문은 필사 문화에서 인쇄 문화로의 이행기에 잉글랜드와 부르고뉴의 문화적인 교류를 책과 인쇄 문화를 중심으로 살펴보고 있다. 이 글의 주인공은 특히 플랑드르의 책 문화와 관련이 깊은 두 잉글랜드 인이다. 우선 요크 왕가의 에드워드 4세는 부르고뉴의 책 문화에 크게 자극을 받고 플랑드르 귀족의 장서관을 모방하여 자신의 개인 장서관을 만들었다. 이 장서관은 후일 영국 왕립도서관의 전신이 되었다. 그렇지만 그의 장서는 단순히 플랑드르의 책을 모방한 것이라기보다는, 소유주의 이해관계에 따라 텍스트의 내용을 전유하는 모습을 보여주고 있다. 한편, 잉글랜드 최초의 인쇄업자 윌리엄 캑스턴 역시 부르고뉴 공국과 관련이 깊은 인물이었다. 1468년에 잉글랜드 국왕 에드워드 4세의 누이 요크의 마거릿이 부르고뉴 공작부인이 된 이후, 플랑드르에서 활동하던 잉글랜드 상인 캑스턴은 마거릿의 후원 하에 『트로이 이야기』를 프랑스어에서 영어로 번역하였다. 특히 그는 자신의 첫 역서를 당시의 신기술인 인쇄술을 사용하여 브뤼주에서 출판하였다. 캑스턴이 부르고뉴 문화의 영향을 받았다는 점은 인쇄 활자체에서도 잘 드러난다. 『트로이 이야기』 등 대륙에서 제작된 그의 책들은 필사본에 널리 사용되던 부르고뉴 바스타드체로 인쇄되었다. 그렇지만 1476년에 고향 잉글랜드로 귀국한 이후에는 대륙과는 다른 독특한 바스타드체를 사용하면서, 대륙의 문화를 잉글랜드 스타일로 새롭게 재창조하였다. This article aims to study cultural exchanges between England and Burgundy, focusing on book cultures during the period of transition from the manuscript to the print culture in the late fifteenth century. At that time, Flanders under the rule of the Valois Dukes of Burgundy was a prosperous centre of economy and culture. It had also maintained a close relationship with England politically, economically and culturally. This study highlights two English historical figures who had deep relations with Burgundian (especially Flemish) book cultures: Edward IV and William Caxton, the first English printer. Edward IV is often named as "the founder of the Royal Library" in England. Highly influenced and stimulated by the Burgundian book culture, he established his personal library by modeling it on the library of a Flemish aristocrat, Lodewijk van Gruuthuse. He also purchased most of his illuminated manuscripts from the prominent professional workshops in Flanders. However, this was not a mere imitation. The English king`s reception of books mainly depended on his own interests, as it is attested in the manuscript of the Miroir historial produced in a Flemish workshop. The first English printer William Caxton had also a close tie with the duchy of Burgundy. Initiated as a mercer, he finished his apprenticeship in Flanders and lived in Bruges for more than thirty years. However, his life met a turning point when Margaret of York, sister of Edward IV, got married to the Charles the Bold and became the duchess of Burgundy in 1468. In fact, William Caxton translated The recuyell of the historyes of Troye, from French into English under her patronage. He printed his first book in Bruges as introducing printing, the newest technology of the time. In so doing, he used the ``Burgundian bastard font`` in his initial publication. This font, more legible to the lay public, had been very popular in the duchy of Burgundy and frequently used in manuscripts and in printing of Flanders. However, after he returned to England and set up a press at Westminster in 1476, Caxton conceived an English style of bastard font in his printed books. It signifies that he was not merely influenced from the book cultures of the Continent, but he created a new English style of print culture.

역사 텍스트의 편집과 주석 달기-근대 초 올리비에 드 라마르쉬의 『회고록』 출판을 중심으로-

이혜민 ( Lee Hye-min ) 한국서양사학회 2017 西洋史論 Vol.0 No.132

역사 기록은 저술 자체뿐만 아니라 편집을 통해서도 구성되거나 변형되곤 한다. 근대 초 인쇄본 출판에서 편집은 완전히 중립적이고 객관적인 작업이 아니었다. 이 연구는 중세의 역사 텍스트가 근대 초의 편집과 주석 달기 과정에서 어떻게 (재)해석되는지 살펴보는 것을 목표로 한다. 올리비에 드 라마르쉬의 『회고록』은 장 제목, 주석, 서문 등의 부가텍스트 붙이기 작업을 통해서 근대적인 편집자가 중세의 텍스트를 당대의 역사적 맥락에 맞추어 정치적으로 재해석하여 수용하는 모습을 잘 보여주는 사례이다. 특히 장 로텐스가 개정한 제2판에는 종교개혁의 와중에서 프랑스와 합스부르크 세력을 모두 배격하면서 새롭게 정치적인 정체성을 형성해나가던 저지대 지방 사람들의 역사관이 드러나고 있다. 프랑스인 편집자 드니 소바주의 초판의 경우 정치적인 색채가 직접적으로 드러나지는 않는 편이지만, 로텐스는 부속텍스트에서 미세하게 나타나는 그의 정치성을 포착해서 강력하게 비판한다. 요컨대, 근대 초의 역사 텍스트 인쇄본에서 부가텍스트는 근대적인 편집자의 역사관과 정치관을 물질적인 페이지 위에서 직접적이고 가시적으로 전달해주는 매개체였다. The history in the sense of historiography is constructed not only by writing, but editing as well. Editorial work was by no means neutral and objective in the production of printed books in the early modern era, and this is well-attested in the editions of Memoires of Olivier de La Marche. This study examines how a medieval historical text was (re-)interpreted in the process of editing and annotating during the early modern period. The Memoires of Olivier de La Marche show how a historical text has been politically interpreted and appropriated by modern editors through the process of inserting paratextual apparatus, such as chapter headings, notes, and editor`s prefaces, in accordance with the historical contexts of the time. Particularly, the second edition by Jean Lautens represents the historical perspective of the Flemish people who, in the midst of the Reformation, were constructing a new political identity by rejecting both the French and Habsburg forces. Lautens strongly criticizes the first edition of Denis Sauvage, a French royal historiographer. Even though Sauvage does not express his own political views explicitly, Lautens captures his political view as biased, as implied in paratexts. To sum up, editors of historical texts in the early modern era revealed and even argued their political and historical views on page, visually and materially, through the medium of paratexts and editorial works.