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일차성 식도질환에서 신경성 산화질소-합성효소 유전자의 다형성에 대한 연구
이준성 ( Lee Jun Seong ),김연수 ( Kim Yeon Su ),이종은 ( Lee Jong Eun ),정인섭 ( Jeong In Seob ),고봉민 ( Go Bong Min ),홍수진 ( Hong Su Jin ),유창범 ( Yu Chang Beom ),김진오 ( Kim Jin O ),조주영 ( Jo Ju Yeong ),이문성 ( Lee Mun S 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 아칼라지아, 미만성 식도 경련, 호두까기 식도 등은 그 병인을 잘 모르나 서로 연관되어 있고 내인성 억제 신경의 기능에 문제가 있다는 점이 알려져 있다. 억제신경에 가장 중요한 신경전달물질은 산화질소(NO)이며 따라서 신경성 산화질소-합성효소(nNOS) 유전자의 다형성이 이들 질환의 병태생리에 영향을 미칠 가능성이 있다. 본 연구의 목적은 일차성 식도운동질환에서 nNOS 유전자의 다형성을 분석하여 그 차이가 경축성 식도운동질환들의 병태에 미치는
앱시스산 (酸) 에 의해 기공이 (氣孔) 닫히는 신호전달과정에서 G-단백질의 역할
이준상(Joon Sang Lee),이한주(Han Ju Yi),이수민(Su Min Lee),이영숙(Young Sook Lee) 한국식물학회 1994 Journal of Plant Biology Vol.37 No.4
Activation of phospholipase C (PLC) and consequent elevation of inositol 1,4,5-trisphosphate (IP_3) level have been reported during ABA-induced closure of stomata. However, it is not known yet whether G-protein regulates the PLC activity during the process. We tested if G-protein is involved in ABA-induced stomatal closure, using pertussis toxin (PT_χ), which inactivates its substrate G-proteins, and cholera toxin, which activates its substrate G-proteins. PT_χ inhibited ABA-induced stomatal closure both in intact epidermal peels from abaxial surface of Commelina communis L. and in partially digested epidermal tissue of Vicia faba L., which contained only guard cells and no other epidermal cells. Cholera toxin did not show any of the effect. Moreover, PT_χ completely blocked ABA-induced elevation of IP_3 level in partially digested epidermal tissue of V. faba L.. These results indicate that PT_χ-sensitive, PLC-linked G-protein is involved in signal transduction process of ABA in guard cells.
이준노(Jun Ro Lee),이춘수(Chunsoo Lee),최준배(Junbae Choi),강효신(Hyo Shin Kang),임신원(Shin Won Lim),나덕렬(Duk L. Na),김성윤(Seong Yoon Kim),이재홍(Jae-Hong Lee),한설희(Seol-Heui Han),최성혜(Seong Hye Choi),김상윤(Sang Yun Kim),김도관 대한노인정신의학회 2017 노인정신의학 Vol.21 No.2
Objective:We aimed to find the sex differences of the way how educational attainment influence on cognitive function in patients with Alzheimer’s disease (AD). Methods:We recruited 424 patients with AD from a large hospital-based multi-center cohort. We evaluated cognitive subdomains using the Seoul Neuropsychological Screening Battery-Dementia version. We employed multiple linear regression analysis to compare the score of cognitive subdomains between the groups with high versus low educational attainment based on the high school graduate. Interaction between educational attainment and sex was also included in the analysis. Results:High and low educational attainment group had 33.0% and 67.0% of patients in the study population. In the multiple regression analysis, score of all cognitive subdomains were significantly higher in the high educational attainment group. The score of attention was also significantly affected by interaction between educational attainment and sex. This result may be helpful to develop cognitive intervention therapy. Conclusion:In the female patients with AD, educational attainment showed higher influence on the attention score.
이준의 ( Jun Eui Lee ),이상원 ( Sang Won Lee ),이원형 ( Won Hyung Lee ) 한국사진학회 2011 AURA Vol.0 No.24
Humans` eye disparity is 65mm or less. The binocular disparity is an important factor of stereoscopic effect. Humans` stereoscopic feeling of an object is being caused by the double structure of eyes & rod(right brain) and nerve cone(left brain) organized by perceptual system. The rod of right brain affects to stare at an object, and the nerve cone of left brain makes possible to see an object in focused sight. In the principle of camera, they are similar with ``out of focus`` and ``pan focus``. The double structure of left & right brain does not works simultaneously, but it works by turns with delaying, by the double structure of brain such as above, humans are able to see the objects in stereoscopic 3D image. This perceptual system of human makes possible to express the image and video contents in stereoscopic by specific video devices, polarizing lens, red & blue glasses. The screen based stereoscopic images need captured images by two same cameras using the device which is called ``Rig``. Except the stereoscopic 3D images such as pre-produced photos or film, video, animation contents are needed to be produced in frame by frame. For instance, to convert film duration of 100 minutes to stereoscopic contents in manual processes, it needs about 100 to 300 of edit crew and budgets. To complement the disadvantages such as these, in this paper, we suggest the method for converting existing 2D image contents to stereoscopic 3D image contents by real-time 2D/3D image conversion algorithm. The stereoscopic 3D image conversion is the method that is create a stereoscopic image from the photos or videos; and does not get the captured video from stereo camera. First, separate the objects and backgrounds from existing original 2D image, set the distancepixel value from the separated sources, then separate the image in left-right; then adjust the external parameter value of internal and external of camera. Then create a stereoscopic image by move the occlusion area and image according to the camera`s location. Suggested method above presents the three-dimensional effects without any limitations of scene changing; and it converts not only videos, but still images also to stereoscopic images in real-time. The real-time stereoscopic conversion algorithm which was organized above has produced based on the hardware which is called ``Physical Board`` to complement the computational complexity from the limitation of the software`s algorithmic processes, and the drop of data processing speed. From the experiment, if we use the suggested method above, we can omplement the stereoscopic 3D image contents by dimensionalize all of existing 2D image contents to 3D, moreover, we can also save budget for creating stereoscopic 3D image contents production.