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      • 듀얼 에너지 CT의 가상 단색 영상을 이용한 영상 교정 팬텀과 금속 인공음영에 관한 연구

        이준성,이승훈,박주경,이선영,김진기,Lee, Jun seong,Lee, Seung hoon,Park, Ju gyung,Lee, Sun young,Kim, Jin ki 대한방사선치료학회 2017 대한방사선치료학회지 Vol.29 No.1

        목 적: 이중선원 듀얼에너지 CT(DS-DECT)의 가상 단색 영상을 이용해서 영상의 질 향상과 선량학적 영향에 대한 방사선치료계획 이용의 유용성을 평가하고자 한다. 대상 및 방법: DS-DECT를 이용하여 듀얼에너지(80/Sn 140 kVp)와 싱글에너지(120 kVp) 영상을 획득하였다. 영상 교정 팬텀 실험을 위해서 40-140 keV 범위로 단색 영상을 재구성했다. 선량 측정용 고체물등가팬텀 연구에서는 64, 69, 88, 105 keV 단색 영상을 선택했다. 스테인리스 스틸을 포함한 고체물등가팬텀에 $10{\times}10cm^2$ 조사야, SSD 100 cm, 10 MV 광자선, 100 MU 조사선량, 단일빔으로 치료계획을 수립하였다. 방사선량측면도 자료는 중심축에 위치한 4개의 지점에서 구했다. 싱글에너지 CT에서 획득한 다색 영상을 기준영상으로 하고, 가상 단색 영상의 선량학적 결과를 분석하였다. 결 과: 낮은 단색 에너지 수치에서 평균 감약이 증가했다. 7개의 물질 중에서 Teflon이 에너지 의존성이 가장 컸고, 10 keV 수치 상승으로 CT number가 평균 2.48 % 감소했다. 저밀도 공기에서는 단색 에너지에 대한 에너지 의존성이 없었다. Polystyrene, Acrylic은 70 keV 이상에서 안정한 CT number를 나타내었다. CT-ED 변환 곡선은 80 keV 단색 영상과 120 kVp 다색 영상이 비슷하였다. 단색 영상의 에너지가 증가할수록 금속의 식별 능력이 향상되었다. 줄무늬 인공음영은 105 keV 단색 영상에서 높은 감소를 보였지만, 여전히 남아 있었다. 다색 영상과 비교하여 각 영상에 따른 방사선치료계획의 선량학적 차이는 ${\pm}0.7%$ 미만이었다. 결 론: 듀얼에너지 영상의 획득은 싱글에너지에 비해 피폭선량을 감소시킬 수 있고, 가상 단색 영상은 CT number 보정에 유용하였다. 향상된 영상의 질은 인체의 기하구조 묘사와 전자 밀도 분포 형성에 도움이 될 것으로 사료된다. Purpose: To evaluate the image quality improvement and dosimetric effects on virtual monochromatic images of a Dual Source-Dual Energy CT(DS-DECT) for radiotherapy planning. Materials and Methods: Dual energy(80/Sn 140 kVp) and single energy(120 kVp) scans were obtained with dual source CT scanner. Virtual monochromatic images were reconstructed at 40-140 keV for the catphan phantom study. The solid water-equivalent phantom for dosimetry performs an analytical calculation, which is implemented in TPS, of a 10 MV, $10{\times}10cm^2$ photon beam incident into the solid phantom with the existence of stainless steel. The dose profiles along the central axis at depths were discussed. The dosimetric consequences in computed treatment plans were evaluated based on polychromatic images at 120 kVp. Results: The magnitude of differences was large at lower monochromatic energy levels. The measurements at over 70 keV shows stable HU for polystyrene, acrylic. For CT to ED conversion curve, the shape of the curve at 120 kVp was close to that at 80 keV. 105 keV virtual monochromatic images were more successful than other energies at reducing streak artifacts, which some residual artifacts remained in the corrected image. The dose-calculation variations in radiotherapy treatment planning do not exceed ${\pm}0.7%$. Conclusion: Radiation doses with dual energy CT imaging can be lower than those with single energy CT imaging. The virtual monochromatic images were useful for the revision of CT number, which can be improved for target coverage and electron densities distribution.

      • KCI등재

        Parallel Finite Element Analysis System Based on Domain Decomposition Method Bridges

        이준성,염곡 강이,이은철,이양창,Lee, Joon-Seong,Shioya, Ryuji,Lee, Eun-Chul,Lee, Yang-Chang Computational Structural Engineering Institute of 2009 한국전산구조공학회논문집 Vol.22 No.1

        본 논문에서는 대규모 3차원 구조해석에 필요한 병렬 유한요소해석을 위한 영역분할법의 적용에 대해 묘사하였다. 영역분할법을 사용한 병렬 유한요소법 시스템을 개발하였다. 절점 생성시, 절점들간의 거리가 특정절점에서의 공간함수와 같아지면 절점이 생성되어 진다. 이 절점공간함수는 퍼지지식처리에 의해 조절되어 진다. 기본적인 요소생성은 데로우니 삼각화 기법을 적용하였다. 자동요소생성 시스템을 이용한 영역분할법은 3차원 해석에 큰 도움이 된다. 공간함수와 유사하게 절점들간의 유한요소해석을 위한 병렬 수치 알고리즘으로서 영역분할법을 전체의 해석영역을 완전히 여러 개의 작은 영역으로 겹치지 않게 나누는 공역구배인 반복적 솔버와 결합시켰다. 개발된 시스템의 효용성에 대한 성능을 몇 가지 예를 통해 제시하였다. This paper describes an application of domain decomposition method for parallel finite element analysis which is required to large scale 3D structural analysis. A parallel finite element method system which adopts a domain decomposition method is developed. Node is generated if its distance from existing node points is similar to the node spacing function at the point. The node spacing function is well controlled by the fuzzy knowledge processing. The Delaunay triangulation method is introduced as a basic tool for element generation. Domain decomposition method using automatic mesh generation system holds great benefits for 3D analyses. Aa parallel numerical algorithm for the finite element analyses, domain decomposition method was combined with an iterative solver, i.e. the conjugate gradient(CG) method where a whole analysis domain is fictitiously divided into a number of subdomains without overlapping. Practical performance of the present system are demonstrated through several examples.

      • KCI등재
      • KCI등재

        齒牙 및 齒周疾患에 使用되는 藥物에 관한 文獻的 考察

        이준성,유현신,서형식,노석선,Lee, Jun-Seong,Rheu, Hyun-Sin,Seo, Hyung-Sik,Rho, Seok-Seon 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

        The result were as follows: 1. Apply the drug to the Dental and Paradental digease is used to be very busy on the Gypsum Fibrosum( 石膏) and Asari herba cum Radice(細辛). 2. Apply the drug to the Dental and Paradental digease is clearing away heat and helping sweat 3. Apply the drug to the Dental and Paradental digease is cold and hot. 4. Apply the drug to the Dental and Paradental digease is pungent, bitter and sweet. 5. Apply the drug to the Dental and Paradental digease is non-toxic. 6. Apply the drug to the Dental and Paradental digease is used to be very busy on the chanel of liver and stomach.

      • KCI등재

        消風散加味의 抗알레르기 效果에 關한 實驗的 硏究

        이준성,서형식,노석선,Lee, Jun-Seong,Seo, Hyung-Sik,Roh, Seok-Seon 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

        This study was carried out to prove the anti-allergic effect of SPS-GM, which is gained by controlled Cytokines making all the difference to Th2 cell development. The results were obtained as follows : 1. From the SPS-GM treatment about BMC cell, in case of the IL-4, an important factor of the Th2 cell development, SPS-GM didn't show considerable effect. 2. The INF-${\gammer}$, mutual Cytokines of IL-4, was increased more than twice. 3. Histamine from the Master cell and Nitric oxide from indisposition response were a little decreased. According to the above results, it is suggested that SPS-GM has anti-allergic effect.

      • KCI등재

        건성안 환자에서 쇼그렌증후군의 빈도 및 임상양상

        이준성,최원,이신석,윤경철.Jun Sung Lee. MD. Won Choi. MD. Shin Seok Lee. MD. Kyung Chul Yoon. MD. PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.4

        Purpose: To investigate the prevalence and clinical aspects of Sjögren syndrome in patients who were diagnosed with dry eye syndrome in Korea. Methods: The medical records of patients who were diagnosed with dry eye syndrome in a dry eye clinic during a 2-year period (March 2008 to March 2010) and were followed up for more than 3 months were reviewed retrospectively. Results: A total of 206 patients were included in the present study. Fifty-eight patients (28%) had Sjögren syndrome and 39 patients (19%) showed primary Sjögren syndrome. Sjögren syndrome patients showed poorer results than non-Sjögren syndrome patients in ocular surface disease index score (OSDI), tear break up time, Schirmer test score, and ocular surface staining score using the Oxford scheme (p < 0.05). Among the patients with primary Sjögren syndrome, 27 patients were SSA (anti-Ro antibodies) or SSB (anti-La antibodies) positive and 12 patients were sero-negative. There were no statistically significant differences in objective or subjective parameters between the sero-positive and sero-negative groups. Conclusions: Sjögren syndrome was observed in 28% of all dry eye patients, in two-thirds of severe dry eye patients. Sjögren syndrome patients showed more severe clinical aspects than dry eye patients with non-Sjögren syndrome. Diagnosing Sjögren syndrome through systemic evaluation is necessary in the patients with severe dry eye. J Korean Ophthalmol Soc 2012;53(4):499-504

      • 154kV 지중송전케이블에서 Wavelet을 이용한 Fault Location에 관한 연구

        이준성,문성철,이종범,Lee, Jun-Seong,Mun, Seong-Cheol,Lee, Jong-Beom 대한전기학회 2000 전기학회논문지A Vol.49 No.12

        This paper describes a fault location technique using wavelets in underground transmission power cable system. Estimation of fault location is performed using data smapled at two ends underground system. In the case of 50% fault of total underground transmission line, fault location is calculated using sampled single-end data in underground transmission line. Traveling wave is utilized in capturing the travel time of the transients along the monitored lines between the relay and the fault point. This traveling time information is provided by the wavelet. Simulation was performed using EMTP, ATP Draw and MATLAB. The results of fault location shown in this paper will be evaluated as an effective suggestion for fault location in real underground transmission line.

      • KCI등재

        정瘡에 對한 文獻的 考察

        이준성,노석선,Lee, Jun-Seong,Roh, Seok-Seon 대한한방안이비인후피부과학회 2000 한방안이비인후피부과학회지 Vol.13 No.2

        1. The furuncle is nail shaped, whitch tip is sharp and root is deep, very dangerous. It's progress is so rapid and it corresponds to the acute suppurative infection of western medicine. 2. The cause and pathology of the furuncle were divided into three parts, inappropriate care (improper diet and excessive sex), surgical trauma (epidernic infection by domestic animal as like cattle, hoarses, pigs, sheep etc), external evil. 3. The early syndrome of the furuncle is swollen pain, various change of color, fidgetiness, restlessness, aversion to cold, headache, nausea and vomitting etc. Though apply acupuncture, there is no pain and bleeding. There may be streak of blood, curdy of muscles and widen swolling. If it is progressed, its sphere becomes diffuse. This is called as the serious case of furuncle(정독주황). 4. The maim treatment of the furuncle is clear away heat and toxic materials. The method was moxibustion, sticking-plaster, purge blood, oral taking the medicine of detoxication and fire extinguishing etc. 5. The main prescriptionst are omisodokyum(五味消毒飮), hwangyeonheadoktang(黃連解毒湯), ohyangyeongyotang(五香連翹湯), hyeongbangpaedoksan(荊防敗毒散) and so on. The main external prescriptionst are okrhosan(玉露散), cheonchugo(千 膏), guildao(九一丹), palyidan(八二丹), taeyulgo(太乙膏), hongyugo(紅油膏) and so on.

      • KCI등재

        미세각막절개도를 이용한 데스메막박리 각막내피층판이식술의 국내 장기 임상 결과

        이준성,박영걸,윤경철,Jun Sung Lee,Yeoung Geol Park,Kyung Chul Yoon 대한안과학회 2010 대한안과학회지 Vol.51 No.11

        Purpose: To evaluate the long-term results of Descemet’s stripping automated endothelial keratoplasty in Korea (DSAEK). Methods: Seven patients with bullous keratopathy who underwent DSAEK and who were followed-up for more than 18 months were reviewed retrospectively. Best corrected visual acuity, refraction, corneal thickness, and endothelial cell count were examined before and after surgery. Results: The mean follow-up period was 19.9 ± 2.9 months (18 to 24 months), and the mean age was 61.42 ± 10.13 years (46 to 76 years). Six patients (85.7%) showed successful results after surgery. Best corrected visual acuity (logMAR) was significantly improved from 1.62 (median) to 1.15 (median) (p = 0.027) at one month after surgery and was maintained until the final follow-up period. There were no statistical differences in spherical ametropia or astigmatism before or 18 months after the operation. Graft failure was observed in one case, in which penetrating keratoplasty was performed 12 months after DSAEK. Conclusions: Long term results of DSAEK showed fast visual recovery, low ametropia and astigmatism. DSAEK may be a good option for the surgical management of corneal endothelial disease. J Korean Ophthalmol Soc 2010;51(11):1431-1437

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