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이종균(Jong Kyun Lee),이풍렬(Poong Lyul Rhee),이준혁(Joon Hyeok Lee),이규택(Kyu Taek Lee),최성호(Sung Ho choi),노재형(Jae Hyung Noh),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),백승운(Seung Woon Paik),이종철(Jong Chul Rhee) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.4
Benign recurrent intrahepatic cholestasis(BRIC) is a very rare cholestatic condition of unknown etiology and its main clinical feature is multiple recurrent episodes of cholestasis with no extrahepatic bile duct obstruction. Familial and nonfamilial forrns of BRIC have been described. We report a case of two sisters with benign recurrent intrahepatic cholestasis. They have experienced recurrent jaundice since childhood. Extrahepatic bile duct obstructions were excluded by ultrasonography and endoscopic retrograde cholangiopancreatography. Liver biopsy specimens showed centri]obular hepatocytic cholestasis. Lobular architectures and portal tracts were well preserved without inflammation.(Korean J Gastroenterol 1997; 29:249-253)
이종균(Jong Kyun Lee),이풍렬(Poong Lyul Rhee),이준혁(Joon Hyeok Lee),이규택(Kyu Taek Lee),최성호(Seong Ho Choi),노재형(Jae Hyung Noh),김재준(Jae Jun Kim),고광철(Kwang Cheol Ko),백승운(Seung Woon Paik),이종철(Jong Chul Rhee) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.1
N/A Backgroud/Aims: For many years, it has been thought that gallstone disease was relatively rare and pigment stone was prevalent in Korea. But a few recent studies showed that 60-70% of gallbladder stones in Korea were cholesterol stone. This study was designed to obtain a prevalence and risk factors for gallstone in Korea. Methods: A total of 5,126 persons undergoing routine health screening enrolled in this study. All persons were given a questionnaire about smoking habits, alcoho] consumption, parity, and present illness along with its history of management. Height and body weight were checked. They were examined using ultrasonography and hiochemical test such as lipid profiles and fasting blood glucose. Gallstone disease was defined as the presence of posteriorly shadowing, echogenic, movable structures within the gallbladder as determined by ultrasonography and a history of previous cholecystectomy due to gallstones. Chi-square test and stepwise logistic regression analysis assessed the risk factors for gallstone disease. Results: The prevalence of gallstone disease in Korean adults(above 20 years old) was 4.7% in men and 5.2% in women. The age-standardized prevalence was 3.1% and 3.4% respectively. Gallstone disease was more frequent in the older age groups(6.6% in the sixth decade, 12.2% in the seventh decade, and 20.4% in the eighth decade). Age, obesity, hypertriglyceridemia, and diabetes were risk factors for gallstone disease. Smoking, alcohol consumption, parity, and hypercholesterolemia including LDL-C did not differ significantly between persons with and without gallstone disease. Conclusions: The prevalence of gallstone in Korean adults are 3.1% in men and 3.4% in women. The risk factors for gallstone are age, obesity, hypertriglyceridemia, and diabetes. Further studies will be needed about the prevalence of gallstone disease in general population according to the composition of gallstone.(Korean J Gastroenterol 1997; 29:85-92)
담낭 결석이 동반되지 않은 담낭 용종의 악성화 관련 인자
이재승 ( Jae Seung Lee ),이규택 ( Kyu Taek Lee ),정재홍 ( Jae Hong Jung ),오성욱 ( Sung Wook Ok ),최성철 ( Sung Chul Choi ),이광혁 ( Kwang Hyuck Lee ),이종균 ( Jong Kyun Lee ),허진석 ( Jin Seok Heo ),최성호 ( Seong Ho Choi ),이종 대한소화기학회 2008 대한소화기학회지 Vol.52 No.2
Background/Aims: The purpose of this study was to find the factors predicting the neoplastic polyp of gallbladder and analyze the size criteria associated with malignancy. Methods: A total of 354 subjects with gallbladder polyps confirmed by tissue pathology were included for the analysis. The clinical and radiological features of the polyps were compared between the two groups (neoplastic vs. non-neoplastic) and in the three groups (non-neoplastic vs. adenoma vs. adenocarcinoma). The independent factors associated with malignancy were studied. Results: Of 354 patients, non-neoplastic polyps were observed in 229 (64.7%) patents, adenoma in 85 (24.0%) and adenocarcinoma in 40 (11.3%). The mean diameter of non-neoplastic polyp, adenoma, and adenocarcinoma were 11.3±2.8 mm, 16.0±7.2 mm, and 27.0±8.9 mm, respectively. The mean age of patients with non-neoplastic polyp, adenoma, and adenocarcinoma were 44.8±11.3, 49.9±12.5, and 60.8±9.6, respectively. Age, size of polyp, number of polyp, presence of diabetes, and presence of symptom showed statistically significant difference between the neoplastic polyp and non-neoplastic polyp groups. But only age, size of polyp, number of polyp were statistically independent factors associated with neoplastic polyp (p<0.05). To predict the neoplastic polyp, sensitivity was 94.4%, but specificity was 18.3% on the basis of 10 mm criteria. whereas sensitivity and specificity was 76.0% and 55.5% on the 12 mm-criteria. Conclusions: On the basis of our analysis, the size of polyp is the most important factor to predict the malignancy. In the 10 mm criteria, sensitivity is satisfactory but specificity is very low. Therefore 10 mm size should not be considered to be the absolute size-criterion for surgery. (Korean J Gastroenterol 2008;52:97-105)
강태욱(Tae Wook Kang),이규택(Kyu Taek Lee),류민규(Min Kyu Ryu),문원(Won Moon),배문희(Mun Hee Bae),이경수(Kyung Su Lee),이상수(Sang Soo Lee),이지민(Ji Min Lee),조건영(Gun Young Cho),이종균(Jong Kyun Lee),백승운(Seung Woon Paik),이종철(J 대한내과학회 2001 대한내과학회지 Vol.60 No.4
N/A Background: Cystic tumors of the pancreas are uncommon, and frequently mistaken for pancreatic pseudocysts. Recently if the patient is a good surgical candidate and is symptomatic, resection is the treatment of the choice without the cytological and chemical analysis by the fine needle aspiration. But, we have no data in Korean population. The aim of this study was to evaluate the subclassification of the cystic tumors of the pancreas and the differential points between pancreatic pseudocysts and cystic tumors of the pancreas which had to be operated. Methods: fifty-nine patients with cystic lesions of the pancreas have been operated at the Samsung Seoul Hospital from 1994 to 1999 and evaluated about the subclassification, frequency and the difference between pseudocysts and cystic tumors retrogradely. Results: There were 14 mucinous cystic neoplasms (mucinous cyst adenomas: 11 cases, mucinous cyst-adenocarcinomas : 3 cases), 10 serous cyst adenomas, 9 solid and papillary epithelial neoplasms, 8 intra-ductal papillary mucinous neoplasms, 5 pseudocysts, 4 retention cysts, 3 endocrine tumors, 1 pancreatic ductal adenocarcinoma with cystic change, 1 solid pseudopapillary tumor, 1 pancreatic ductal adenocarci-noma with pseudocyst , 1 cavernous lymphangioma, 1 lymphoepithelial cyst and 1 simple cyst. 57.6% of the patients were females and the mean age was 50.0 years (16 year s-77years). The characteristics between pseudocysts and cystic tumors of the pancreas (sex differentiation, mean age, previous history of alcohol drinking and pancreatitis, communication with the main duct on the pancreatogram and the sign of the pancreatitis on the radiologic study) had no differences. Conclusion: We conclude there were no other methods to differentiate accurately the pseudocyst from the cystic tumor of the pancreas other than the operation.(Korean J Med 60:349- 357, 2001)