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산전검사를 시행하지 않은 산모에서 태어난 신생아의단순 포진 바이러스 2형 뇌염 1례
이은섭 ( Eun Seob Lee ),김준영 ( Joon Young Kim ),이건희 ( Kon Hee Lee ),이정원 ( Jung Won Lee ),이용주 ( Yong Ju Lee ),오연정 ( Yeon Joung Oh ),방지석 ( Ji Seok Bang ),성태정 ( Tae-jung Sung ) 대한주산의학회 2014 Perinatology Vol.25 No.3
Neonatal herpes simplex virus (HSV) encephalitis is a rare disease nowadays because of prenatal screening test and management. It shows progressive central nervous system manifestations affecting predominantly temporal and frontal lobes. Early diagnosis of HSV encephalitis is important since even with the early initiation of high-dose intravenous acyclovir therapy, it results in serious morbidity among survivors. A 14-day-old neonate with fever and poor oral intake was admitted via emergency department. The next day she had seizures and the brain was damaged with permanent sequelae despite of early administration of intravenous acyclovir on day 2 of admission. We report a serious case of HSV encephalitis diagnosed as type 2 HSV by PCR and culture of a newborn who was delivered by a mother without proper prenatal screening test.
학령전기 만성 기침 환아에서 알레르기 감작의 위험 요인
이은섭 ( Eun Seob Lee ),방지석 ( Ji Seok Bang ),오연정 ( Yeon Joung Oh ),이정원 ( Jung Won Lee ),성태정 ( Tae Jung Sung ),이용주 ( Yong Ju Lee ),이건희 ( Kon Hee Lee ) 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.2
Purpose: Chronic cough is one of the major symptoms of asthma and allergic sensitization and may appear prior to the onset of asthma. The object of this study was to investigate the risk of allergic sensitization in preschool children with chronic cough. Methods: We reviewed the medical records of 99 preschool children presenting with chronic cough but not with allergic rhinitis, atopic dermatitis, recurrent wheezing, or lower respiratory tract infection between November 2011 and July 2013. Results: Fifty-four children (55%) were sensitized at least one of the following inhalant allergens: Dermatophagoides pteronyssinus, Dermatophagoides farinae, cockroach, Alternaria alternata, dog dander, and cat epithelium. Children with allergic sensitization had a higher blood total IgE levels transformed by common logarithm (1.9±0.6 IU/mL vs. 1.3±0.5 IU/mL, P<0.001) and eosinophils (3.7%±2.5% vs. 2.7%±2.0%, P=0.043), more frequent parental history of allergy (68% vs. 48%, P=0.044) and less frequent history of breast milk feeding (68% vs. 86%, P=0.041) than those without. Conclusion: These results suggest that the ratio of allergic sensitization may be 50% or more in preschool children with chronic cough and that parental history of allergy and formula milk feeding may be associated with allergic sensitization. (Allergy Asthma Respir Dis 2015;3:105-108)
이은섭(Lee, Eun-sup) 중앙어문학회 2013 語文論集 Vol.53 No.-
This paper aims to investigate the characteristics of the second person pronoun ‘그대[keudae]’. Even though this pronoun is the correspondence of ‘너[neo]’(you) which is the most general second pronoun in the aspect of the addressee-honorifics, some people take it for third person pronoun in some instances recently. This case is originated from several causes.<br/> Most of all, when a addressee is invisible at the scene of discourse, some misread who is referred ‘그대’ as the third person she or he. Also since some changes occurred in the addressee-honorific system diachronically, the distribution scope of ‘그대’ became to cover all kinds of honorific styles.<br/> ? However we can identify the characteristics as the second person pronoun of ‘그대’ to be still steady. At first, ‘그대’ occurred in the imperative and the propositive without any constraints. There are no possibility that people would interpret it as the third person.<br/> At second, as ‘그대’ often combines with the vocative case marker ‘여[yeo]’, it would be introduced into the discourse as a addressee automatically. Besides, ‘여’ has some restriction in combining with other person pronoun. Therefore we reaffirmed that ‘그대’ has solid status as a second person pronoun.
이은섭(Eun-Sup, Lee),김선옥(Sun-Ok, Kim) 한국통상정보학회 2006 통상정보연구 Vol.8 No.2
This paper discusses the definition of the term “domestic industry” in relation to the application of the safeguards provisions of the WTO through the judicial interpretation made by the WTO Appellate Body and panel. The requirements for the imposition of safeguards include a rapid increase in import quantity, the existence of serious injury or threat of serious injury to the domestic industry, and a causal relationship between the increase in imports and the industrial injury. The domestic industry refers to the producers that account for a considerable portion of the total national production, or the national producers who produce articles “like” or “directly competitive” with the specific imports. Chronically, there have been controversial disputes relating to the interpretation of the term “like” or “directly competitive”. Reviewing the disputes relating to the term “domestic industry” in application of the safeguards provisions since the establishment of the WTO, the interpretation of the term “like” has been made imposing weight on the physical characteristics of the products. This interpretation is in contrast with that of the interpretation of the term “directly competitive” which has been interpreted with imposed weight on the commercial elasticity of substitution which can be measured by the final use or consumer’s taste.
WTO체제하 무역과 환경의 조화를 위한 “동종상품”의 판단기준
이은섭(Eun-sup Lee),이양기(Yang-kee Lee) 한국국제상학회 2006 國際商學 Vol.21 No.1
One of the most controversial issues in interpreting the product under the GATT/WTO in linking trade with environmental policies is defining what is "like product". Even though the WTO Appellate Body"s decision, differently from the panels" decisions under the GATT, opened the door for environmental consideration to be taken into account in determining "like product", it is still unclear whether the Appellate Body takes into account the environmental concerns arising solely from the process and production methods of a product in determining the likeness of product. In order to balance the value of free-trade and environmental protection, the value of environmental protection which has arguably rather poorly been evaluated should be advanced by defining the term of "like products" more obviously; i.e. the definition of "like products" should be shifted from the way of emphasizing physical characteristics into the way of emphasizing functional characteristics.
Liraglutide 치료군에서 매주 L-Arginine 주사의 추가 치료에 대한 효능
이은섭(Eun-Sub Lee),정민(Jung-Min Choi),주남석(Nam-Seok Joo) 대한기능의학회 2020 Journal of Korean Institute for Functional Medicin Vol.3 No.1
Background: Recently, liraglutide is considered as an efficient treatment option to control body weight in the obese. However, no data were reported for additional effect of L-arginine injection in the liraglutide treatment patients. Methods: We have designed observational trial to evaluate the difference of body composition by additional L-arginine intravenous injection (15 g, every week) in the liraglutide use patients (3.0 mg everyday) for six months. A total of 130 subjects, we selected the data of 113 subjects who completed six months’ treatment. The data were composed of one university hospital (liraglutide group, n=21) in Suwon city and one obesity clinic (liraglutide+L-arginine group, n=92) in Seoul. Results: After six months, body weight (liraglutide vs liraglutide+L-arginine; -4.6 kg vs. -5.6 kg; P=0.286), lean body mass (liraglutide vs liraglutide+L-arginine; -0.7 kg vs. -1.1 kg; P=0.940), and body fat mass (liraglutide vs liraglutide+L-arginine; -3.5 kg vs. -3.7 kg; P=0.618) were not different between the two groups. Conclusion: No additional body compositional changes were observed after additional L-arginine injection in liraglutide treatment patients. 연구 배경: Liraglutide 피하주사는 비만환자에서 체중감량 조절에 유용한 치료방법이다. 그러나 현재까지 liraglutide 와 함께 L-arginine 정맥주사를 병행하여 치료한 연구는 없었다. 따라서 본 연구는 liraglutide를 쓰는 환자에서 L-arginine 정맥주사를 병행했을 때 추가적인 체중 감량 및 체성분 변화가 있는지를 평가하였다. 방법: 본 연구는 관찰연구로서 6개월간 liraglutide (3.0 mg, 매일)를 단독 피하 주사한 군과 liraglutide (3.0 mg, 매일)과 L-arginine (15 g, 매주)을 병행주사한 군의 체성분 변화를 비교하였다. 총 130명의 환자 자료에서 6개월간 치료를 완료한 113명의 자료를 선별하였다. 대상자는 수원시 소재 일개 대학병원(liraglutide군, n=21)과 서울시 소재 일개 비만클리닉 (liraglutide+L-arginine군, n=92)에 내원한 비만환자였다. 결과: 6개월의 치료 후, 체중(liraglutide vs. liraglutide+ L-arginine; -4.6 kg vs. -5.6 kg; P=0.286), 제지방량(liraglutide vs. liraglutide+L-arginine; -0.7 kg vs. -1.1 kg; P=0.940), 체지방량(liraglutide vs. liraglutide+L-arginine; -3.5 kg vs. -3.7 kg; P=0.618)은 두 군 사이에 유의한 차이가 없었다. 결론: Liraglutide 사용 환자에게 L-arginine 주사를 추가하였을 때 liraglutide 단독 치료와 비교하여 추가적인 체중 감량 및 체성분 변화는 없었다.