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TOC와 통계적 분석에 의한 플라스틱보트 제조공정 개선에 관한 연구
윤건구(Gun Gu Yoon),김태구(Tae Gu Kim),이동형(Dong Hyung Lee) 한국산업경영시스템학회 2016 한국산업경영시스템학회지 Vol.39 No.1
The purpose of this paper is to analyze the problems and the sources of defective products and draw improvement plans in a small plastic boat manufacturing process using TOC (Theory Of Constraints) and statistical analysis. TOC is a methodology to present a scheme for optimization of production process by finding the CCR (Capacity Constraints Resource) in the organization or the all production process through the concentration improvement activity. In this paper, we found and reformed constraints and bottlenecks in plastic boat manufacturing process in the target company for less defect ratio and production cost by applying DBR (Drum, Buffer, Rope) scheduling. And we set the threshold values for the critical process variables using statistical analysis. The result can be summarized as follows. First, CCRs in inventory control, material mix, and oven setting were found and solutions were suggested by applying DBR method. Second, the logical thinking process was utilized to find core conflict factors and draw solutions. Third, to specify the solution plan, experiment data were statistically analyzed. Data were collected from the daily journal addressing the details of 96 products such as temperature, humidity, duration and temperature of heating process, rotation speed, duration time of cooling, and the temperature of removal process. Basic statistics and logistic regression analysis were conducted with the defection as the dependent variable. Finally, critical values for major processes were proposed based on the analysis. This paper has a practical importance in contribution to the quality level of the target company through theoretical approach, TOC, and statistical analysis. However, limited number of data might depreciate the significance of the analysis and therefore it will be interesting further research direction to specify the significant manufacturing conditions across different products and processes.
추출 온도와 시간이 옻나무 추출물의 항산화활성에 미치는 영향
박혜진(Hye Jin Park),윤건묵(Gun Mook Yoon),이상훈(Sang Hoon Lee),장귀영(Gwi Yeong Jang),김민영(Min Young Kim),Li Meishan,이준수(Junsoo Lee),정헌상(Heon Sang Jeong) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.11
추출 온도와 시간에 따른 옻나무 부위별 추출물의 총 페놀 및 플라보노이드 함량과 항산화활성을 측정하였다. 옻나무 추출물의 총페놀 함량은 추출 온도 160℃에서 47.82 mg GAE/g으로 가장 높았으며, 100℃ 이하의 추출 온도에서는 유의적인 차이가 없었으나 120℃ 이상의 추출 온도에서는 추출 시간 3시간까지는 증가하다가 5시간에서는 감소하였다. 총 플라보노이드는 추출 온도가 증가함에 따라 증가하여 140℃, 1시간에서 8.04 mg CE/g으로 가장 높은 함량을 나타내었다. DPPH 라디칼 소거활성은 추출 시간의 증가에 따라 증가하여 140℃, 3시간에서 34.23 mg TE/g으로 가장 높았으며, 그 이후에는 감소하였다. ABTS 라디칼 소거활성은 DPPH 라디칼 소거활성과 유사하였고 140℃에서 3시간 추출한 수피 추출물에서 51.58 mg AEAC/g으로 높게 나타났다. 총 페놀과 총 플라보노이드 함량과 DPPH와 ABTS 라디칼 소거활성을 감안할 때 옻나무 부위별 효율적인 추출 조건은 추출 온도 140℃와 추출 시간 3시간이었다. Rhus verniciflua was extracted at different temperatures and times, and the extracts were evaluated for contents of total phenolics and flavonoids, and antioxidant activities using DPPH and ABTS radical scavenging activities. Extraction temperatures and times were 80, 100, 120, 140 and 160℃, and 1, 3 and 5 hr. The total phenolic and flavonoid contents as well as antioxidant activities by DPPH and ABTS increased as the extraction temperature increased. The total phenolic contents did not significantly increase at less than 100℃ with different extraction times. However, they were increased at 3 hr and decreased at more than 120°C. The total flavonoid contents reached a high value of 8.04 mg CE/g at 140℃. The antioxidant activity by DPPH increased as the extraction temperature increased and reached high values of 34.28 mg TE/g at 140℃. The total antioxidant activity by ABTS was similar to DPPH. These results presumed that the optimum extraction temperature and time in the process of Rhus verniciflua extraction are 140℃ for 3 hr.
박혜진(Hye Jin Park),이상훈(Sang Hoon Lee),장귀영(Gwi Yeong Jang),Meishan Li,김민영(Min Young Kim),김성태(Sung Tae Kim),이지현(Ji Hyun Lee),윤건묵(Gun Mook Yoon),이준수(Junsoo Lee),정헌상(Heon Sang Jeong) 한국식품영양과학회 2015 한국식품영양과학회지 Vol.44 No.1
추출 온도와 시간에 따른 옻나무의 주요 페놀화합물의 함량을 부위별로 분석하고 이들의 효율적인 추출조건을 확립하였다. 옻나무 추출물의 gallic acid 함량은 추출 온도가 증가함에 따라 증가하여 수피의 160°C, 5시간 처리구에서 385.33 mg%로 가장 높았다. Protocatechuic acid 함량은 수피의 120°C, 1시간 처리구에서 9.25 mg%로 높았지만 그 이상의 온도에서는 크게 감소하였다. Fustin은 120°C 이상에서는 감소하였으며 목질의 100°C, 3시간 처리구에서 206.97 mg%로 가장 높았다. Fisetin은 추출 온도가 증가함에 따라 증가하여 목질부의 160°C, 5시간 처리구에서 가장 높았다. Sulfuretin은 fisetin과 유사한 경향을 나타내었으며, 목질부의 160°C, 3시간 처리구에서 16.40 mg%로 가장 높았다. Butein은 추출 온도 및 추출 시간이 증가함에 따라 증가하였으며, 목질부의 160°C, 5시간 처리구에서 1.49 mg%로 가장 높았다. 통계분석 결과 옻나무의 주요 페놀화합물 추출에 영향을 미치는 요인은 추출 온도가 가장 큰 것으로 나타났다. 유효성분, 추출 수율, 경제성 등을 감안할 때 옻나무 부위별 효율적인 추출조건은 추출 온도 140℃와 추출 시간 3시간이었다. This study investigated changes in phenolic contents of different parts of Rhus verniciflua Stokes (RV) according to extraction conditions. Bark and xylem parts of RV were extracted at 80, 100, 120, 140, and 160°C for 1, 3, and 5 h, respectively. Major phenolic compounds (gallic acid, protocatechuic acid, fustin, fisetin, sulfuretin, and butein) of RV were analyzed. The gallic acid, fisetin, sulfuretin, and butein contents significantly increased as extraction temperature increased. Protocatechuic acid and fustin contents increased as increasing extraction temperature to 120°C and decreased afterward. The gallic acid, protocatechuic acid, and butein contents of bark were higher than those of xylem extracts. The optimal extraction conditions of gallic acid, protocatechuic acid, fustin, fisetin, sulfuretin, and butein were 160°C/3 h (380.22 mg%), 120°C/1 h (9.25 mg%), 100°C/3 h (206.97 mg%), 140°C/5 h (93.84 mg%), 140°C/5 h (16.07 mg%) and 160°C/5 h (1.49 mg%), respectively. These results suggest that the optimum extraction temperature and time considering RV extraction yield and cost are 140°C and 3 h, respectively.
박재호 ( Jae-ho Park ),정지은 ( Jieun Chung ),강혜정 ( Hye Jeong Kang ),오하경 ( Ha Kyung Oh ),이경희 ( Kyeong Hee Lee ),김영호 ( Youngho Kim ),윤건묵 ( Gun-mook Yoon ),엄현주 ( Hyun-ju Eom ) 한국식품영양학회 2017 韓國食品營養學會誌 Vol.30 No.4
This study investigated the nutritional compositions and physiochemical properties of three domestically cultivated jujube fruits (Boeun, Sangwhang, and Bokjo). Nutrient contents were analyzed by freeze-drying the jujube fruits. The results showed that the proximate compositions of the three jujube cultivars ranged from 7.85~13.52% for moisture, 4.65~5.24% for crude protein, 1.29~2.38% for crude ash, 0.17~1.09% for crude lipid, and 7.66~16.63% for crude fiber. The above proximate contents of jujube cultivars were significantly different. Mineral contents of Al, Fe, Mg, Ca, Na, and K in the three jujube fruits were also determined. Mn, Cu and Zn were not detected in any of the varieties. The content of Al was higher in Sangwhang, while Boeun had higher contents of Ca and K. The total polyphenol, ABTS values, and hypoglycemic effect were slightly higher in Boeun as compared to the other varieties. Taken together, Boeun could be an important source of natural antioxidant as a functional food.
이민희(Min Hee Lee),채종률(Jong Ryul Chae),최윤건(Yoon Gun Choi),장필식(Pil Sik Jang),박형근(Hyoung Gun Park) 대한내과학회 1988 대한내과학회지 Vol.35 No.3
N/A The clinical features and laboratory findings of 123 patients with histologica]ly confirmed Hashimoto's thyroiditis were examined from April 1984 to December 1987 at the Masan Koryo General Hospital. The results were as follows: 1) All 123 patients with Hashimoto's thyroiditis were women and the age distribution showed the peak incidence between the second and fourth decades (Average of 35 years). 2) Eighty-four cases (68.3%) had a moderately diffuse goiter, 106 cases (86.2%) firm and 98 cases (79.7%) had symmetrical swelling of the glands. Thirty-Seven cases (30.1%) were palpated as nodular surfaced thyroids. 3) All 123 patients could be divided into three groups according to the thyroid function test on initial visits, i. e. euthyroid 59 cases (48.0%); hypothyroid, 49 cases (39.8%) and hyperthyroid, 15 cases (12.2%), 4) The positive rate for antithyroglobulin and antimicrosomal antibody were 30.8% and 74.5%. The difference in the titer of antibodies according to the thyroid function status could not be observed. 5) One hundred thyroid scans were studied and classified into the following groups: 48 cases (48%) showed diffuse enlargement with inhomogeneous uptake, 18 cases (18%) showed diffuse enlargement with increased uptake, 16 cases (16%) showed normal appearance, 13 cases (13%) showed cold areas, and 5 cases (5%) showed both lobes faintly visualized. 6) The thyroid needle biopsy is considered as a safe, important diagnostic tool for differential diagnosis and for determining the prognosis. 7) With thyroid hormone therapy, goiters were reduced and various symptoms were improved in the hypothyroid group.