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이민희(Min Hee Lee),채종률(Jong Ryul Chae),최윤건(Yoon Gun Choi),장필식(Pil Sik Jang),박형근(Hyoung Gun Park) 대한내과학회 1988 대한내과학회지 Vol.35 No.3
N/A The clinical features and laboratory findings of 123 patients with histologica]ly confirmed Hashimoto's thyroiditis were examined from April 1984 to December 1987 at the Masan Koryo General Hospital. The results were as follows: 1) All 123 patients with Hashimoto's thyroiditis were women and the age distribution showed the peak incidence between the second and fourth decades (Average of 35 years). 2) Eighty-four cases (68.3%) had a moderately diffuse goiter, 106 cases (86.2%) firm and 98 cases (79.7%) had symmetrical swelling of the glands. Thirty-Seven cases (30.1%) were palpated as nodular surfaced thyroids. 3) All 123 patients could be divided into three groups according to the thyroid function test on initial visits, i. e. euthyroid 59 cases (48.0%); hypothyroid, 49 cases (39.8%) and hyperthyroid, 15 cases (12.2%), 4) The positive rate for antithyroglobulin and antimicrosomal antibody were 30.8% and 74.5%. The difference in the titer of antibodies according to the thyroid function status could not be observed. 5) One hundred thyroid scans were studied and classified into the following groups: 48 cases (48%) showed diffuse enlargement with inhomogeneous uptake, 18 cases (18%) showed diffuse enlargement with increased uptake, 16 cases (16%) showed normal appearance, 13 cases (13%) showed cold areas, and 5 cases (5%) showed both lobes faintly visualized. 6) The thyroid needle biopsy is considered as a safe, important diagnostic tool for differential diagnosis and for determining the prognosis. 7) With thyroid hormone therapy, goiters were reduced and various symptoms were improved in the hypothyroid group.