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- 저자 : 박형근(Hyoung Gun Park) (검색결과 6 건)
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한국인 HBsAg 양성간질환환자에 있어서 HBeAg 및 anti - HBe 의 검출성적
박형근(Hyoung Gun Park),김익모(Ik Mo Kim),이재준(Jae Hun Lee),김경진(Kyung Jin Kim),지혜기(Hye Kee Jee) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.2
N/A Authers carried out studies to determine the frequency of HBeAg and anti-HBe in the serum of l4 patients with HBsAg-positive liver diseases, wbo were diagnosed by clinically, biochemically, serologically and morphologically from March, 1980 to Sept., 1981 in Department of Internal Medicine, Gospel Hospital, Kosin Mfedical College. HBsAg, HBeAg and anti-HBe were measured by method of solid phase radiommunoassay with the Abbott- Ausria system. We also investigated the correlation between HBeAg and findings of chemical liver function test. The results obtained were summarized as follows; 1) The positivity of HBeAg was 84.6% in chronic active hepatitis, 66. 7% in acute type B hepatitis, 62.5% in chronic persistent hepatitis, 61.4% in liver cirrhosis, 46.27% in primary hepatoma, and 28. 0% in asymptomatic HsAg carriers. The positivity of HBeAg in acute and chronic hepatitis and liver cirrhosis was significantly higher than that in prirmary hepatoma and aSx HBsAg carriers. 2) The positivity of anti-HBe was 50.0% in aSx HBsAg carriers, 46. 2% in primary hepatoma, 25.0% in chronic persistent hepatitis and liver cirrhosis, and 15.2%. In acute type B hepatitis, respectively. The anti-HBe was not detected in chronic active hepatitis. The positivity of anti-HBe in aSx HBsAg carriers and primary hepatoma were significantly higher than that of the others. 3) In aSx HBsAg carriers and patients with acute type B hepatitis, liver cirrhosis and primary hepatoma, mean levels of serurn GPT, GGTP, bilirubim, or alpha-fetoprotein were not significantly different between patients with and without HBeAg. 4) In chronic active and persistent hepatitis, mean levels of serum GPT of the patient with HBeAg were significantly higher than that of the patients without HBeAg, but serum bilirubin levels were not distinctly different between them. On the basis of above findings, it was suggested that HBeAg is chiefly detected in patients with HBsAg(+) active liver disease such as acute and chronic hepatitis, while anti-HBe chiefly detected in patients with inactive liver diseases such as asymptomatic HBsAg carriers and primary hepatoma.
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건강성인 및 급 , 만성 간질환환자에서 간염 B 바이러스의 혈청학적 표지의 분포양상
백영직(Young Jick Baek),박형근(Hyoung Gun Park),김익모(Ik Mo Kim) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.2
N/A Until the introduction of anti-HBc (the antibody to HBcAg), HBsAg and anti-HBs were used as the main serological markers for the detection of HBV infection. However, after the recognition of anti-HBc as an indicator of ongoing hepatic viral replication, anti-HBc has been widely used for the evaluation of the status of various HBV infection in addition to HBsAg and anti-HBs and its clinical signifcances were approved. We carried out the study on the distribution pattern of serological HBV markers in 129 healthy adults and 150 patients with acute and chronic liver diseases at the Department of Internal Medicine, Kosin Medical College during the period hetween Jan. 1980 and Aug. 1980. The results were summarized as followings; l. 86.05% of healthy adults in Korea have the serological evidences of previous HBV infection. Among them, the group positive for anti-HBc alone was the most common and the next was the group positive for both anti-HBc and anti-HBs. The incidence of positivity of HBsAg in healthy adults was 8. 53%. Also, serum HBsAg was more prevalent in young age group, but as the age increases. The group positive for both anti-HRc ar d anti-HBs became more common. 2. In. Korea, most cases of acute and chronic hepatitis, liver cirrhosis and primary hepatoma revealed the serological evidence of previous HBV infection. Unlike the results from.'healthy adults, among the patients with liver diseases the group positive for both HBsAg and anti-HBc was the most common, and the group positive for anti-HBc alone was the next common. 3, Serum anti-HBc level was higher in patients with liver diseases, especially chronic active hepatitis than in healthy adults. On the basis of above results, the prevalence rate of HBV infection in Korea, after the use of anti-HBc, was much higher than that of previous results.
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이민희(Min Hee Lee),채종률(Jong Ryul Chae),최윤건(Yoon Gun Choi),장필식(Pil Sik Jang),박형근(Hyoung Gun Park) 대한내과학회 1988 대한내과학회지 Vol.35 No.3
N/A The clinical features and laboratory findings of 123 patients with histologica]ly confirmed Hashimoto's thyroiditis were examined from April 1984 to December 1987 at the Masan Koryo General Hospital. The results were as follows: 1) All 123 patients with Hashimoto's thyroiditis were women and the age distribution showed the peak incidence between the second and fourth decades (Average of 35 years). 2) Eighty-four cases (68.3%) had a moderately diffuse goiter, 106 cases (86.2%) firm and 98 cases (79.7%) had symmetrical swelling of the glands. Thirty-Seven cases (30.1%) were palpated as nodular surfaced thyroids. 3) All 123 patients could be divided into three groups according to the thyroid function test on initial visits, i. e. euthyroid 59 cases (48.0%); hypothyroid, 49 cases (39.8%) and hyperthyroid, 15 cases (12.2%), 4) The positive rate for antithyroglobulin and antimicrosomal antibody were 30.8% and 74.5%. The difference in the titer of antibodies according to the thyroid function status could not be observed. 5) One hundred thyroid scans were studied and classified into the following groups: 48 cases (48%) showed diffuse enlargement with inhomogeneous uptake, 18 cases (18%) showed diffuse enlargement with increased uptake, 16 cases (16%) showed normal appearance, 13 cases (13%) showed cold areas, and 5 cases (5%) showed both lobes faintly visualized. 6) The thyroid needle biopsy is considered as a safe, important diagnostic tool for differential diagnosis and for determining the prognosis. 7) With thyroid hormone therapy, goiters were reduced and various symptoms were improved in the hypothyroid group.
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이명철,고창순,박형근,양영식,박원창 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1
Bone scan is a very useful technique for detection of aseptic necrosis and frequently used in the detection of aseptic necrosis of the femoral head. We have used this diagnostic tool in a patient to detect aseptic necrosis of the talus, a common complication resulting from foot injuries.
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