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Spatial-Temporal Modelling of Road Traffic Data in Seoul City
이상열,안수한,박창이,전종우,Lee, Sang-Yeol,Ahn, Soo-Han,Park, Chang-Yi,Jeon, Jong-Woo The Korean Data and Information Science Society 2002 한국데이터정보과학회지 Vol.13 No.2
Recently, the demand of the Intelligent Transportation System(ITS) has been increased to a large extent, and a real-time traffic information service based on the internet system became very important. When ITS companies carry out real-time traffic services, they find some traffic data missing, and use the conventional method of reconstructing missing values by calculating average time trend. However, the method is found unsatisfactory, so that we develop a new method based the spatial and spatial-temporal models. A cross-validation technique shows that the spatial-temporal model outperforms the others.
소의 뇌로부터 Calmodulin 단백질의 순수분리 및 생화학적 성질 연구
이상열,권헌영,김정희,이서구 ( Sang Yeol Lee,Heun Young Kwon,Jung Hye Kim,Sue Goo Rhee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.2
Calmodulin, a heat stable Ca^(++)-binding protein, is a multifunctional modulator, mediating many of the Ca^(++) effects in cellular functions. This protein interacts reversibly with Ca^(++) to form a protein/ Ca^(++) complex, whose activity is regulated by cellular flux of Ca^(++). Calmodulin from bovine brain was purified to complete homogeneity by heat, acid treatment and hydrophobic interaction chromatography. The biochemical properties of the purified protein were examined under various criteria. It was estimated to have an apparent molecular weight of 21K and 15K in the absence or presence of Ca^(++) respectively, which would mean the great conformational changes were induced by the binding of Ca^(++) to calmodulin. The calmodulin had distinct ultraviolet absorption peaks at 259, 265, and 279 nm due to phenylalanine and tyrosine residues. Also, this protein activated the Ins(1,4,5) P₃-Kinase of which role is very important in cellular signal transduction, about seven folds (at 6 μM Ca^(++) and 1.0 μM calmodulin) with a Ca^(++)-dependent manner.
소 위의 Phosphoinositide - specific Phospholipase C Isozymes 에 관한 연구
이상열,문경호,이기영 ( Sang Yeol Lee,Kyung Ho Moon,Kee Young Lee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.4
Expression of multiple PLC isozymes was studied in bovine stomach of rumen, reticulum, omasum and abomasum. The soluble protein of stomach homogenates was resolved on a DEAE column using high performance liquid chromatography. The PLC enzymes from the stomach of rumen, reticulum, omasum and abomasum were eluted from the DEAE-column at 26-30 min and 41-46 min. Comparing the retension times of stomach PLC enzymes with those of bovine brain PLC isozymes, the PLC in the first and second peak might be corresponded to PLC δ and either of PLC β or γ respectively. This result was clearly confirmed by monoclonal antibodies derived against PLC β, γ and δ of bovine brain. In immunoblot analysis, PLC in the first activity peak from bovine stomach was blotted only with the antibody against PLCδ, and the second peak PLC was reacted with the antibodies against both PLC β and γ, which showed that the second peak contained both PLC β and γ. Using monoclonal antibodies which bind to different epitopes on the same enzyme, tandem radioimmunoassay was performed for quantitating the amounts of PLC in this organ. The concentration of PLC δ in bovine stomach of rumen, reticulum, omasum and abomasum that appeared in the first peak from HPLC-DEAE column was in the range of 10-14 ㎍ and those of PLC β and γ in second peak were 1-2 ㎍ and 5-18 ㎍ per 100 ㎎ soluble protein of bovine stomach homogenates respectively. This paper demonstrated that bovine stomach contain the type δ as the major form of PLC and relatively small amounts of PLC β and γ.
기저면의 넓이와 상지 근육의 최대 수의적 등척성 수축의 상관관계
이상열,조맑은,Lee, Sang-Yeol,Jo, Marg-Eun 대한고유수용성신경근촉진법학회 2016 PNF and Movement Vol.14 No.1
Purpose: The purpose of the present study was to examine the effects of the area of the base of support formed by the human body on the maximal voluntary isometric contraction of upper limb muscles. Methods: The study was conducted with 20 normal adults. To identify changes in the base of support, the maximal voluntary isometric contraction of the biceps muscle was measured in a standing position, a sitting position, and a lying position for each subject. The sizes of the base of support formed in the standing, sitting, and lying positions were set to 1, 2, and 3 respectively, based on the sizes, to analyze the correlations. The maximal voluntary isometric contraction of the biceps muscle was measured using surface electromyograms (EMGs) (Noraxon DTS, Germany). Results: The results showed negative correlations in which, as the size of the base of support increased, the maximal voluntary isometric contraction of the biceps muscle decreased. Conclusion: Changes in the base of support of the body affect the maximal voluntary isometric contraction of the upper limbs. Therefore, when resistance exercises are applied for muscle strengthening, the positions should be changed considering the changes in muscle activity according to those positions. In addition, when EMGs are used to measure the maximal voluntary isometric contraction, the measurements should be conducted in the same positions, considering muscle activity that changes according to the base of support and positions, for data quantification.
H2-M3의 세포 표면 발현이 NK 세포의 활성에 미치는 영향 분석
이상열,전태훈,Lee, Sang-Yeol,Chun, Tae-Hoon 대한약학회 2009 약학회지 Vol.53 No.3
H2-M3 (M3) is a unique antigen presenting molecule which provides N-formylated peptide to certain type of T cells. Previous observation indicated that NK cell activity is significantly diminished during listerial infection in $H2-M3^{-/-}$ mice. To explore the possibility that M3 expression directly effect on NK cell activity, we measured NK cell activity with or without stimulation of N-formylated peptide on antigen presenting cells. Results indicated that the expression of M3 is not directly influence on NK cell activity. Further study will be focused on the indirect effect of M3 on regulating NK cell activity.
COVID-19로 인해 발생한 업무의 피로도와 직무소진의 상관관계 및 직무스트레스와의 회귀분석 연구 -물리치료사를 대상으로-
이상열,최수홍,김인균,오강오,윤성영,석힘,허재석,Lee, Sang-Yeol,Choi, Su-Hong,Kim, In-Gyun,Oh, Kang-O,Yoon, Sung-Young,Seok, Him,Heo, Jae-Seok 대한고유수용성신경근촉진법학회 2021 PNF and Movement Vol.19 No.2
Purpose: This study was conducted to investigate the type of physical therapist response work and its intensity, along with the prolonged prevalence of COVID-19, to determine the impact on physical therapists' occupational stress and occupational burnout. Methods: An online survey was conducted with 118 physiotherapists and collected the participants' gender, final educational background, clinical work experience, workplace type, additional workload, and fatigue associated with COVID-19. After excluding one participant who submitted an incomplete questionnaire, 117 respondents were included in the final data. Results: Additional COVID-19-related workloads and response reliability for fatigue, occupational burnout, and occupational stress were shown to have Cronbach's alpha measures of 0.76, 0.89, and 0.87, respectively. Groups who had experienced a new epidemic in the past showed higher fatigue levels (3.06±0.94) than those groups who had no such experience (2.49±0.84; p < 0.05). Correlation analysis of COVID-19 work fatigue and occupational burnout scales showed a positive correlation (r = 0.19; p < 0.05). The regression of occupational burnout and occupational stress showed a regression model of Y = 20.00+0.43X<sub>1</sub> (X<sub>1</sub>: job stress; p< 0.05) and an explanatory power of 24.8% with an adj.R<sup>2</sup> = 0.25. Conclusion: Based on the results, it is suggested that various institutions, such as medical institutions, educational institutions, and physiotherapists' associations, should seek ways to manage and alleviate physiotherapists' stress.