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토끼에서 저체온증의 유발에 의한 생리학적 및 임상병리학적 변화
이병한,한진수,정병현,Lee, Byeong-han,Han, Jin-soo,Chung, Byung-hyun 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.4
The studies were carried out to investigate the phygiological changes in deep hypothermia in rabbits. Sixty rabbits were continuously cooled with femoral arterio-venous bypass circulation to rectal temperatures of $34.0{\pm}0.3^{\circ}C$(mild hypothermia), $30.0{\pm}0.3^{\circ}C$(moderate hypothermia), and $25.0{\pm}0.3^{\circ}C$(deep hypothermia). The results obtained in these experiments were summarized as follows : In mild, moderate, and deep hypothermia, MAP, HR, RR, pH, $pCO_2$, $pO_2$, $Na^+$, $K^+$, HCT, PLT, glucose, L-lactate, BUN, and creatinine were analyzed. During hypothermia, a statistically significant decrease of MAP occurred between $30^{\circ}C$ and early $25^{\circ}C$(Start) of rectal temperature while significant increases occurred between baseline($38.7^{\circ}C$) and $30^{\circ}C$. Significant decreases of HR and RR were observed in the rabbits, particularly those changes appeared to similar patterns in proportion to hypothermia. Significant decreases of pH occurred between $34^{\circ}C$ and $25^{\circ}C$, and significant increases of $pO_2$ and $pCO_2$ were observed continuously in the hypothermic rabbits. The hypothermia had no significant effect on blood $Na^+$ and serum creatinine. Blood $K^+$ significantly decreased from $3.1{\pm}0.5$(baseline) to $2.6{\pm}0.6mmol/l$($34^{\circ}C$) with the hypothermia for about 30 minutes, and significantly increased from $2.4{\pm}0.6$($25^{\circ}C$(S)) to $2.7{\pm}0.5mmol/l$($25^{\circ}C$(E)) with the hypothermia for 2 hrs. HCT significantly increased to $34^{\circ}C$, thereafter, continuously increased to $25^{\circ}C$(Start, End). PLT increased to $34^{\circ}C$, thereafter, continuously decreased to $25^{\circ}C$(Start, End). Also PLT decreased significantly from 414.3($30^{\circ}C$) to $308.8{\times}103/mm^3$($25^{\circ}C$, Start). Significant increases of blood glucose and L-lactate occurred between $30^{\circ}C$ and $25^{\circ}C$ (Start, End). Slight increase of serum BUN continuously appeared with the hypothermia. These results, such as characteristic changes of the significant decrease of pH and PLT at $34^{\circ}C$, the significant decrease of MAP at $30^{\circ}C$, and the significant increase of glucose and l-lactate at $30^{\circ}C$, suggest that homeostasis of rabbits to hypothermia rapidly decreases at $34{\sim}30^{\circ}C$ of rectal temperature. Therefore, we suggest that, during the period with the rapidly decreased homeostasis, the very carefully control and treatment need to recover hypothermic animals under the circumstances of the various hypothermic experiments and emergency medicine.
이병한,전원철,김진영,김종성,박정환,박종성,한진수,정병현,Lee, Byeong-han,Chun, Won-chul,Kim, Jin-young,Kim, Jong-sung,Park, Jung-hwan,Park, Jong-jung,Han, Jin-soo,Chung, Byung-hyun 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.1
The studies were carried out to investigate the effect of recovery in rewarming using the esophageal thermal tube in the deep hypothermia($25{\pm}1^{\circ}C$ ; rectal temp) in rabbits. Fifteen rabbits were divided into control group(n=6), peritoneal dialysis group(n=5) irrigated with dialysate at $42{\pm}1^{\circ}C$, and esophageal rewarming group(n=4) perfused with circulating water at $38{\pm}1^{\circ}C$. Rewarming of the rabbits was performed for 5 hours. MAP, HR, RR, esophageal temp, rectal temp, pH, $pCO_2$, $pO_2$, $Na^+$, and $K^+$ were observed. The results obtained in these experiments were summarized as follows : Esophageal rewarming group($38{\pm}1^{\circ}C$) had more effect on esophageal temperature than other groups. Peritoneal dialysis group($42{\pm}1^{\circ}C$) had more effect on rectal temperature and $pO_2$ than other groups. The both groups also had more effects on MAP, HR, RR, and $pCO_2$ than control group. Three groups had no significant effect on pH, $Na^+$, and $K^+$. In conclusion, we found that the simple, safe, and non-invasive esophageal rewarming method had an effect on the treatment of profound hypothermia as well as the peritoneal dialysis method in spite of the temperature difference between the dialysate and the circulating water, and the circulating water at $38{\pm}1^{\circ}C$ for esophageal rewarming also had an effect on the recovery of deep hypothermia.
이병한(Lee, Byeong Han) 역사비평사 2013 역사비평 Vol.- No.103
This paper examines a Chinese perspective on North Korea and North Vietnam in the wake of Wei Wei that was written during the Korean War and the Vietnam War. The focus is on the term ‘The East(Dong Fang)’ as a symbol to explain asymmetric relations and mutual perceptions between the New China and the New Korea/NewVietnam. The relations and perceptions between these countries were still strongly influenced by the long history of a Sino-Centric World Order. As such Sino-centric socialism is the modernized Sino-centric world order that was operating in East Asia’s socialist countries inside ‘Bamboo Curtain’, and had very different dynamics from relations between the Soviet Union and Eastern Europe, or the Unites Stated and the Asian Alliance. ‘The East(Dong Fang)’ is the sign and symbol of the Sino-centric socialism sphere of East Asia.