제주지역 다지교차로의 회전교차로 교통시스템 변환에 따른 효과분석

이동원(Lee, Dong Weon),고상익(Ko, Sang Ick),이동욱(Lee, Dong Wook) 대한토목학회 2012 대한토목학회논문집 D Vol.32 No.6D

회전교차로는 평면교차로의 일종으로 교차로 중앙에 원형교통섬을 두고 교차로를 통과하는 자동차가 원형교통섬을 우회하도록 하는 교차로 형식이다. 본 연구에서는 신호교차로와 회전교차로의 운영 및 경제적 효과를 분석하기 위해서 제주지역의 5개 교차로를 중심으로 회전교차로 설치에 따른 비교 분석을 실시하였다. 분석 결과 차량평균지체 측면에서 신호교차로에 비해 회전교차로가 65.6%%에서 91.77%의 개선효과가 있는 것으로 분석되었다. 차량운행비용과 시간가치비용을 종합한 교통 혼잡비용의 효과를 분석한 결과, 년간 58.59%(D intersection)에서 81.69%(B intersection)의 비용절감 효과가 있는 것으로 분석되었다. 이를 통해 제주지역의 경우 신호교차로에 비해서 회전교차로가 운영 효과가 뛰어난 것으로 조사되었다. Roundabout is an intersection that allows vehicles to pass through the intersection by circulating the circular traffic island at the center of the intersection. In this study, a comparative analysis was conducted on roundabout at five locations in order to deduce the operational result and financial effect of roundabout and signal intersection. As for the operational result, it was found that roundabout showed improvement effect in the average delay per vehicle compared to that of signal intersection by minimum of 65.6% and maximum of 91.77%. it was found that roundabout showed financial cost-saving effect in the traffic congestion cost compared to that of signal operation by minimum of 58.59% and maximum of 81.69% per year. It can be known from these analysis results that roundabout has significant operational effects under certain amount of traffic volume by allowing vehicles to pass through the intersection in a continuous way without much waiting time and stoppage from signal control.

역 모낭성 각화증의 임상적 고찰 및 Human Papillomavirus의 검색에 관한 연구

안성구,이인욱,최응호,이원수,이승헌,이동원 ( In Wook Lee,Eung Ho Choi,Sung Ku Ahn,Won Soo Lee,Seung Hun Lee,Dong Won Lee ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.6

Background : Inverted follicular keratosis has distinctive histopathological features and is infre quently encountered by dermatologists. To date, the pathogenesis of inverted follicular keratosis has not, been concluded. Many authors have suggest,ed several theories for the nature of invert.ed follicular keratosis including vearuca vulgaris with squamous eddies, irritated seborrheic keratosis and dist,inctive follicular tumors. Objective : It is the purpose of this study to observe and compare the clinical features of in verted follicular keratosis with previous studies and evaluate the possible relationship between in verted follicular keratosis and human papillomavirus to clarify the nature of this condition. Methods : We studied 9 patients with inverted follicular keratosis for clinical features including the duratiori of the disease, the location and size of the lesions, the clinical impressions at the first visit and we made a record of the patients age and sex. To evaluate the relationship be tween inverted follicular kerato is and the human papillomavirus, we performed immunohistochvm ical staining using polyclonal antibodies to the human papillomavirus common antigen. We also used the polymerase chain relation to detect hurnan papillomavirus DNA in inverted follicular keratosis from paraffin embedded tissue preparation. Results : 1. Seven of the 9 patients,vere male and the ages ranged fiom 36 to 77 years(mean 53 years). The lesions were situat d on the face(4/9),abdomen(1/9), back(1/9), chest(1/9), scapular area(1/9) and leg(1/9). The average size of the lesions was 1.5 cm. Verruca vulgaris was the most common clinical diagnosis(3/9), followed by seborrheic keratosis(2/9), soft fibroma(2/9), pigmented nevi(1/9), and granioloma pyogenicum(1/9). 2. Immunohistochemical stainiiigs using polyclonal antibodies to the human papillomavirus common antigen were negative for all 9 cases. 3. Polymerase chain reaction; using primers for human papillomavirus DNA were negative for all 9 cases. Conclusipn : In general, our linical findings are similar to those of others in previous studies. Our results of immunohistocheriiical staining and the polymerase chain reactions suggest, that in vert,ed follicular keratosis is ncl, related to the human papillomavirus. Further investigat.ions inf'o the nature of invert,ed follicular keratosis, should be centered on initated seborrheic keratosis and distinct follicular tumor s. (Korean J Dermatol 1997;35(6): 1074-1081)

다중 경로 기반 홈네트워크 시스템 설계 및 평가

이동원(Dong-Won Lee),정광욱(Kwang-Wook Jung),송도선(Do-Sun Song) 한국정보기술학회 2006 한국정보기술학회논문지 Vol.4 No.4

By the economical growth human‘s life became convenient but more advanced convenient & abundant life style is required based on the integration of computer and communication technology. One of example is home network system and some company already developed home network system with integration of some technology. Therefore in these days the development and evaluation method to the hardware, software, communication and control skill, should be set up. And education and training for engineers who developing or manufacturing or repairing home network system, is absolutely required. In this thesis we studied existing home network system and also developed more compact and convenient home network system which has multi paths by using wire & wireless communication technology, and finally we evaluated the system performance.

일측요관폐쇄 생쥐에서 발생된 족세포의 세포자멸사와 TGF β1-LAP의 역할

이동원 ( Dong Won Lee ),강미선 ( Mi Seon Kang ),강선우 ( Sun Woo Kang ),김양욱 ( Yang Wook Kim ),김영훈 ( Yeong Hoon Kim ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.3

목적: TGF-β1이 신장에서 간질 섬유화와 족세포의 손상을 일으키는 데 중요한 역할을 함이 잘 알려져 있다. 본 저자들은 일측요관폐쇄로 신섬유화를 일으킨 실험동물에서 복강내 TGF-β1 LAP의 투여로 신섬유화와 족세포의 세포 자멸사를 막을 수 있는지를 알아보았다. 방법: 24 마리의 생쥐에게 좌측 요관 결찰술을 시행하였다. 그 중 12마리의 생쥐와 수술 받지 않은 8마리 중 4마리의 생쥐에게 TGF-β1 LAP를 복강내로 주사하였다. 수술 후 3, 7, 14, 21일에 생쥐들을 수술군과 비수술군 각각 3마리, 1마리씩 희생시켜 좌측 신장의 조직을 얻었다. 조직학적 검사를 하여 족세포의 세포자멸사를 관찰하였다. 결과: 신우의 확장과 간질 섬유화는 시간이 경과함에 따라 비례하여 증가됨이 관찰되었다. LAP를 투여한 실험군에서는 대조군에 비해 족세포의 세포 자멸사가 적었고, WT-1의 발현도 유지되었다. 또한 실험군에서 대조군에 비해 단백뇨도 적었다. 결론: 유전자 재조합된 LAP의 복강 내 투여는 요관 결찰술을 받은 생쥐의 14일까지의 TGF-β1의 발현을 일부 억제하고 신장의 손상을 지연시키며 족세포의 소실을 막을 수 있었다. Purpose: It was well known that transforming growth factor (TGF)-β1 plays a pivotal role in interstitial fibrosis and loss of podocyte. We explored the effects of exogenous administration of TGF-β1 latency-associated peptide (LAP) in a model of renal fibrosis induced by unilateral ureteral obstruction (UUO) and examined whether TGF-β1 LAP can inhibit apoptosis of podocyte. Methods: Twenty four male BALB/c mice were unilaterally obstructed of proximal ureters by ligation. Half of the mice with operation and half of 8 control were administered recombinant human LAP intraperitoneally. One to three mice per group were euthanized on days 3, 7, 14, and 21 after operation for observation of renal fibrosis and apoptosis of podocyte. Results: Interstitial fibrosis was less severe in LAP-treated group. Obstructed kidneys from LAP-untreated mice had more glomerular apoptotic podocytes (TUNEL assay) compared to LAP-treated mice at day 7, 14, and 21 after operation. Conclusion: Intraperitoneal administration of TGF-β1 LAP prevents the loss of podocyte & renal damage partially up to day 14 after operation.

감마분포 공정을 위한 변동계수 관리도의 통계적 설계

이동원(Dong-Won Lee),백재원(Jae-Won Paik),강창욱(Chang-Wook Kang) 한국산업경영시스템학회 2006 한국산업경영시스템학회지 Vol.29 No.2

Recently, the control chart is developed for monitoring processes with normal short production runs by the coefficient of variation(CV) characteristic for a normal distribution. This control chart does not work well in non-normal short production runs. And most of industrial processes are known to follow the non-normal distribution. Therefore, the control chart is required to be developed for monitoring the processes with non-normal short production runs by the CV characteristics for a non-normal distribution. In this paper, we suggest the control chart for monitoring the processes with a gamma short runs by the CV characteristics for a gamma distribution. This control chart is denoted by the gamma CV control chart. Futhermore evaluated the performance of the gamma CV control chart by average run length(ARL).

장기간 복막 투석 환자에서 발생된 프레드니솔론에 반응한 호산구성 복막염

이동원 ( Dong Won Lee ),김광민 ( Kwang Min Kim ),김동욱 ( Dong Wook Kim ),백주은 ( Joo Eun Baek ),윤지철 ( Ji Chul Yun ),박동준 ( Dong Jun Park ),장세호 ( Se Ho Chang ) 대한내과학회 2006 대한내과학회지 Vol.70 No.-

센서네트워크 기반의 차량 돌발구간 예측 시스템 설계와 구현

이동원(Dong-Won Lee),김시관(Si-Gwan Kim),정광욱(Kwang-Wook Jung) 한국정보기술학회 2009 한국정보기술학회논문지 Vol.7 No.2

There are lots of problems, like traffic accident, traffic jams due to increase in the number of vehicles. So, the government started to find a solution for managing the limited resource of road more effectively by using new technology, and then ITS was operated. However, ITS mainly collects information which is focused on traffic jam and traffic flow. Also, the progress of collecting information which goes to the driver is complicated. For this reason, it does not have enough effectiveness and rapidity for gathering urgent information, such as sudden stop of a vehicle, traffic accident and dangerous situation like a parked car on shoulder of a road. In this paper, we study the possibility of commercial use of the system for prediction of vehicle of incident. and present the sensor network system economically by using low cost sensors like acceleration sensor, electrical compass without expensive infrastructure set up.

장기간 복막 투석 환자에서 발생된 프레드니솔론에 반응한 호산구성 복막염

이동원 ( Dong Won Lee ),김광민 ( Kwang Min Kim ),김동욱 ( Dong Wook Kim ),백주은 ( Joo Eun Baek ),윤지철 ( Ji Chul Yun ),박동준 ( Dong Jun Park ),장세호 ( Se Ho Chang ) 대한내과학회 2006 대한내과학회지 Vol.70 No.2S

내측 반월상 연골 후각 부착부 봉합술 시 표층 내측측부인대 유리술의 효과

양병세,이동원,남상욱,하정구,김진구,Yang, Byung Se,Lee, Dhong Won,Nam, Sang Wook,Ha, Jeong Ku,Kim, Jin Goo 대한관절경학회 2012 대한관절경학회지 Vol.16 No.2

목적: 내측 반월상 연골 후각 부착부 봉합술 시 시행하는 표층 내측측부인대 유리술의 유용성 및 안전성에 대해 연구하고자 하였다. 대상 및 방법: 2006년 4월부터 2010년 9월까지 표층 내측측부인대 유리술을 시행하지 않고 내측 반월상 연골 후각 부착부 봉합술을 시행한 환자 20명(PM군)과 표층 내측측부인대 유리술을 시행하고 봉합술을 시행한 시행한 환자 32명(RM군)을 대상으로 하였다. 동반 수술을 시행한 환자는 제외하였다. 안정성 검사로 술 후 3개월, 1년 추시 시 압통, 주관적 불안정성 및 외반 부하 검사를 시행하였고, 유용성 검사로 압박대 사용시간을 비교하였고, 임상 결과는 Lysholm 점수와 International Knee Documentation Committee (IKDC) 점수로 평가하였다. 결과: 전례에서 표층 내측측부인대 유리술과 관련하여 임상적으로 의미 있는 합병증은 없었다. 술 후 3개월 및 1년 추시 관찰 시 압통, 주관적 불안정성에서 음성을 보였으며, 5명의 환자에서 외반 부하 검사상 grade I의 불안정성을 보였다. 압박대 사용 시간은 PM군 $53.5{\pm}13.6$분, RM군 $41.3{\pm}12.7$분으로 두 군간 차이를 보였다(P<0.05). 술 후 임상결과는 PM군은 술 전 Lysholm 점수 $56.8{\pm}5.5$에서 술 후 $85.1{\pm}5.8$로(P<0.001), 술 전 IKDC 점수 $42.6{\pm}6.3$에서 술 후 $77.2{\pm}6.3$로(P<0.001), RM군은 술 전 Lysholm 점수 $56.2{\pm}5.4$에서 술 후 $87.4{\pm}3.9$로(P<0.001), 술 전 IKDC 점수 $42.7{\pm}5.7$에서 술 후 $89.6{\pm}2.9$로(P<0.001) 개선되었다. 두 군간 수술 전, 후의 Lysholm 점수, IKDC 점수 차이는 없었다(P>0.05). 결론: 표층 내측측부인대 유리술은 슬관절 내측 수술 시 시야 확보에 유리하며, 수술 시간을 줄일 수 있고, 임상적 의미있는 잔존 불안정성을 남기지 않아 내측 반월상 연골 후각 부착부 봉합술 시 유용한 것으로 사료된다. Purpose: The purpose of the study was to evaluate the usefulness and the stability of the superficial medial collateral ligament (MCL) release in posterior medial meniscus root repair. Materials and Methods: We compared 20 patients who underwent posterior medial meniscus root repair with superficial MCL preserved (PM) and 32 patients who underwent posterior medial meniscus root repair combined with superficial MCL release (RM) from April 2006 to September 2010. We excluded the patients combined with other surgery. To evaluate the postoperative valgus instability in RM group, we examined direct tenderness on MCL insertion, the subjective feeling of instability and valgus stress test at 3 months and 1 year follow-up. We compared the tourniquet time between PM group and RM group, and the clinical results were assessed by Lysholm score and International Knee Documentation Committee (IKDC) for the usefulness. Results: All patients had no clinically significant complication related to the superficial MCL release. Three months and 1 year follow-up, there were no positive tenderness test, no subjective symptoms and no significant increase of valgus instability although 5 patients examined grade I valgus instability. The mean tourniquet time was $41.3{\pm}12.7$ minutes in RM group and $53.5{\pm}13.6$ minutes in PM group. There was a significant difference in the tourniquet time between the two groups (P<0.05). Average Lysholm score was $56.8{\pm}5.5$ (range, 44-70) preoperatively and $85.1{\pm}5.8$ (range, 77-94) postoperatively in PM group, and was $56.2{\pm}5.4$ (range, 45-67) preoperatively and $87.4{\pm}3.9$ (range, 82-95) postoperatively in RM group (P<0.001). No significant difference of Lysholm score was found in both groups (P<0.05). Average IKDC scores was $42.6{\pm}3.9$ (range, 30-53) preoperatively and $77.2{\pm}6.3$ (range, 68-92) postoperatively in PM group, and was $42.7{\pm}5.7$ (range, 30-53) preoperatively and $89.6{\pm}2.9$ (range, 84-95) postoperatively in RM group (P<0.05). There was also no significant difference of IKDC score in both groups (P<0.05). Conclusion: The superficial MCL release in posterior medial meniscus root repair is useful to gain a wide surgical field and reduces the tourniquet time and does not lead to postoperative valgus instability. It can be considered clinically useful and safe procedure in medial meniscus posterior root repair.

나이관련황반변성에 대한 항혈관내피성장인자 14회 유리체내주사: 완료시기와 임상결과

한재욱(Jae Wook Han),김종우(Jong Woo Kim),김철구(Chul Gu Kim),이동원(Dong Won Lee),한정일(Jung Il Han),유영주(Young Ju Lew),김재휘(Jae Hui Kim) 대한안과학회 2017 대한안과학회지 Vol.58 No.9

Purpose: To evaluate the clinical course of patients who had completed 14 ranibizumab or aflibercept monocular treatments. Methods: Retrospective medical record analysis was performed to 24 patients who were diagnosed with monocular neovascular age-related macular degeneration and had completed 14 ranibizumab or aflibercept monocular injections, allowed by the Korean National Health Care system. Time to completion was measured along with the percentage and timing of medication switch. Best-corrected visual acuity (BCVA) was measured at the time of diagnosis, after 3-loading injections, and the time of completion. Additionally, we searched for any other factors that had influenced the time to completion. Results: The average time to completion of 14 injections was 32.3 ± 6.2 months (21–48 months). The switching was performed in 17 eyes (70.8%), and it was done after 9.4 ± 2.1 injections (4–14 injections) with prior medication. After 14 injections, the BCVA improved in 6 eyes (25.0%), unchanged in 8 eyes (33.3%), and worsened in 10 eyes (41.7%). Complete resolution of intraretinal fluid and subretinal fluid after 3 loading injections were observed in 20 eyes, and it was significantly related to time to the first recurrence and time to the completion of 14 injections (p = 0.007, r = 0.583). Conclusions: The average time to completion of 14 injections was 32.3 months, and switching of medication was performed in 70.8%. Longer time to the first recurrence was related to longer completion time. This study will provide useful facts when informing the patients their future treatment plans under the Korean Health Care system. J Korean Ophthalmol Soc 2017;58(9):1042-1049