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말기 유방암 환자에서 발생한 흉막 전이에 의한 거대 종양 1예와 호흡곤란의 치료
이나리,Lee, Na Ri 한국호스피스완화의료학회 2014 한국호스피스.완화의료학회지 Vol.17 No.2
유방암 환자의 흉막 전이는 흔한 소견이다. 흉수가 가장 흔한 증상이고 흉수를 동반하지 않는 흉막 결절이나 흉막 판은 비교적 드물다. 본 환자는 말기 유방암으로 인해 흉수를 동반하지 않는 빠른 속도로 악화되는 거대 흉막 종양이 생겨났고 그로 인해 심한 호흡곤란을 경험했던 환자로 보기 드문 증례로서 보고를 하며 이와함께 말기암환자의 호흡곤란의 치료에 대해 고찰해 보고자 한다. Pleural metastasis from breast cancer is a common manifestation. While pleural effusion is the most frequent finding, it is relatively rare for pleural nodularity and plaque that do not accompany pleural effusion. We report a patient with a rapidly growing huge pleural mass without pleural effusion caused by breast cancer. The patient was treated for severe dyspnea caused by the pleural mass. Along with the case report, we performed a systematic review of management of dyspnea in terminal cancer patients.
Bacillus amyloliquefaciens를 이용하여 콩 종류와 발효온도를 달리하여 제조한 청국장의 특성
이나리,고태훈,이상미,홍창오,박규민,박근태,황대연,손홍주,Lee, Na-Ri,Go, Tae-Hun,Lee, Sang-Mee,Hong, Chang-Oh,Park, Kyu-Min,Park, Geun-Tae,Hwang, Dae-Youn,Son, Hong-Joo 한국미생물학회 2013 미생물학회지 Vol.49 No.1
This study was carried out to investigate the characteristics of Chungkookjang depending on different soybeans and fermentation temperatures using Bacillus amyloliquefaciens C2 isolated from homemade Chungkookjang. The highest protease activity was 854 U/g in yellow soybean Chungkookjang and 847 U/g in black soybean Chungkookjang at $35^{\circ}C$. The highest amylase activity was 3.87 U/g at $40^{\circ}C$ in yellow soybean Chungkookjang and 4.96 U/g at $45^{\circ}C$ in black soybean Chungkookjang. The highest reducing sugar content was 16.11 mg/g at $40^{\circ}C$ in yellow soybean Chungkookjang and 19.08 mg/g at $45^{\circ}C$ in black soybean Chungkookjang. The highest amino type nitrogen content was 420 mg%/g in yellow soybean Chungkookjang and 194 mg%/g in black soybean Chungkookjang at $40^{\circ}C$. The highest pH was 7.92 at $40^{\circ}C$ in yellow soybean Chungkookjang and 7.59 at $45^{\circ}C$ in black soybean Chungkookjang. The highest number of viable cell was 9.3 log CFU/g at $40^{\circ}C$ in yellow soybean Chungkookjang and at $35^{\circ}C$ in black soybean Chungkookjang. On the other hand, the lowest ammonia type nitrogen content was 225 mg%/g at $45^{\circ}C$ in yellow soybean Chungkookjang and 80 mg%/g at $40^{\circ}C$ in black soybean Chungkookjang. Yellow soybean Chungkookjang showed high protease activity, pH and amino type nitrogen, whereas black soybean Chungkookjang showed high amylase activity and reducing sugar. 본 연구에서는 가정에서 제조한 청국장으로부터 순수분리한 Bacillus amyloliquefaciens C2를 이용하여 콩 종류와 발효온도에 따른 청국장의 품질 특성 변화를 조사하였다. Protease 활성은 $35^{\circ}C$에서 배양했을 때 황태 청국장에서 854 U/g, 흑태 청국장에서 847 U/g로 가장 높았다. Amylase 활성은 황태 청국장의 경우, $40^{\circ}C$에서 3.87 U/g, 흑태 청국장은 $45^{\cricr}C$에서 4.96 U/g로 가장 높았다. 환원당 함량은 황태 청국장의 경우, $40^{\circ}C$에서 16.11 mg/g, 흑태 청국장은 $45^{\circ}C$에서 19.08 mg/g으로 가장 높았다. 아미노태 질소 함량의 경우, 황태 청국장은 $40^{\circ}C$에서 420 mg%/g, 흑태 청국장은 194 mg%/g로 가장 높았다. pH의 경우, 황태 청국장은 $40^{\circ}C$에서 7.92, 흑태 청국장은 $45^{\circ}C$에서 7.59로 가장 높았다. 황태 및 흑태 청국장의 생균수는 각각 $40^{\circ}C$ 및 $35^{\circ}C$에서 9.3 log CFU/g로 가장 높았다. 반면에 암모니아태 질소 함량은 황태 청국장의 경우, $45^{\circ}C$에서 225 mg%/g, 흑태 청국장은 $40^{\circ}C$에서 80 mg%/g로 가장 낮았다. 황태 청국장은 높은protease 활성, pH 및 아미노태 질소함량을 나타내었다. 반면에, 흑태 청국장은 높은 amylase 활성과 환원당 함량 및 낮은 암모니아태 질소 함량을 나타내었다.
어린이박물관 교사들의 교사학습공동체 참여 경험의 의미 - 서울 소재 어린이박물관의 실시간 온라인 교육프로그램 운영 사례를 중심으로 -
이나리(Lee, Na-Ri),김민진(Kim, Min-Jin) 한국어린이문학교육학회 2021 어린이문학교육연구 Vol.22 No.3
본 연구는 유아 대상의 실시간 온라인 교육프로그램을 개발하고 운영한 S어린이박물관 교사들의 교사학습공동체 참여 경험의 의미를 탐색하는 것에 목적을 둔 사례연구이다. 연구현장은 서울 소재의 어린이박물관으로 연구기간은 2020년 3월부터 2021년 5월까지였으며, 연구참여자는 어린이박물관 교육홍보실에 근무하는 교사 8명이다. 연구결과, 유아를 대상으로 하는 실시간 온라인 교육프로그램의 개발과 운영을 위해 구성된 교사학습공동체 참여 경험은 어린이박물관 교사들에게 첫째, 교사의 디지털 역량을 강화하는 원동력, 둘째, 실천적 학습을 추구하는 교사로 성장하는 기회, 셋째, 유아의 발달 특성을 고려한 교육 설계 능력 향상의 계기, 넷째, 관점의 변화를 통해 낯선 것에 도전하게 하는 힘, 다섯째. 공유, 공감, 공생하는 안식처가 되었다. 이러한 연구결과는 새로운 도전에서의 교사학습공동체 필요성을 시사하고, 어린이박물관 교사 및 유아 교사의 전문성 신장을 위한 교사학습공동체 활성화에 기여할 수 있을 것이다. The purpose of this case study was to review the implications of ‘S’ Children’s Museum Teachers’ participation in the Teacher Learning Community; they developed and operated a live-streaming online education program. The location of this study was Children’s Museum in Seoul. The period of this study was from March to May 2020. The participants in this study were 8 teachers working for the Department of Education and the P. R. department of the museum. As a result, it was found that the teacher learning community for the live-streaming online education program had the following meanings for the teachers; First, it was a driving force of reinforcing teachers’ digital competence. Second, it provided an opportunity for the teachers to pursue practical teaching methods. Third, it also provided a chance for the teachers to enhance their competence in designing an education program that considers the developmental characteristics of preschoolers. Fourth, it was a driving force changing the viewpoints of the teacher and challenging them with unfamiliar things. Fifth, it meant a shelter for sharing, sympathy and symbiosis. These results of this study may well suggest the need for the teacher learning community in terms of new challenges by activating the teacher learning community to enhance the teacher’s and pre-school teacher’s professionalism at the Children’s Museum in Seoul.
증례 : S상 결장암에 동반된 부신생물 말초 호산구증가증 1예
이나리 ( Na Ri Lee ),전승민 ( Soung Min Jeon ),차병효 ( Byung Hyo Cha ),박길효 ( Kil Hyo Park ),이종섭 ( Jong Sup Lee ),문도호 ( Do Ho Moon ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-
저자들은 S상 결장암에 동반된 말초 호산구 증가증이 있는 56세 환자에서 간 및 주위 임파선에 다수 전이가 되어 예후가 불량했던 환자 1예를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Eosinophilia is most commonly associated with allergic disorders or parasitic infestation. However, collagen vascular diseases, drug reactions, radiation therapy, and many types of human cancer are also associated with extensive eosinophilia. Peripheral eosinophilia associated with malignancy is a marker of extensive metastasis and is thus associated with a poor prognosis. A 56-year-old male presented with history of right upper quadrent pain and weight loss. Total white blood count was 29,800/㎣ with 69.2% eosinophilia. Abdominal ultrasonogram showed multiple metastasis in liver and abdominal CT scan showed paraaortic lymph node enlargement. Colonoscopy and biopsy revealed moderate to poorly differentiated adenocarcinoma in sigmoid colon. (Korean J Med 69:S753-S757, 2005)
한국전통발효식품인 청국장에서 분리한 Bacillus methylotrophicus에 의한 항산화물질의 생산
이나리 ( Na Ri Lee ),우가영 ( Ga Young Woo ),장준혁 ( Jun Hyeok Jang ),이상미 ( Sang Mee Lee ),고태훈 ( Tae Hun Go ),이희섭 ( Hee Sup Lee ),황대연 ( Dae Youn Hwang ),손홍주 ( Hong Joo Son ) 한국환경과학회 2013 한국환경과학회지 Vol.22 No.7
Although antioxidant activities of Korean traditional fermented foods were reported by many researchers, study on antioxidant activity of microorganism originated from Korean traditional fermented foods was little. Therefore, we improved condition for antioxidant production by a bacterium isolated from home-made Chungkookjang. We selected a bacterial strain, which showed the highest antioxidative activity, from Chungkookjang and then named GJ. The selected GJ strain was identified as Bacillus methylotrophicus by alignment data of 16S rRNA gene nucleotide sequences. Improved medium compositions for DPPH radical scavenging activity were 0.25% sucrose, 1% peptone, 0.01% MgSO4ㆍ7H2O and initial pH 6.5, respectively. Optimal culture conditions were 30℃, 200 rpm and 4% inoculum volume, respectively. In improved conditions, DPPH radical scavenging activity of GJ reached to 91% in a short time. The strain GJ also possessed ACE inhibition and other antioxidative activities; ACE inhibition activity (49.4%), ABTS radical scavenging activity (99.8%), metal chelating activity (67.9%), SOD-like activity (36.5%) and reducing power (A700=5.982) were observed, respectively. Therefore, our results suggest that B. methylotrophicus Gj strain may be potential candidate for functional foods, cosmetic products for anti-aging and medicine for diseases caused by oxidative stress.