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유효정,박미연,최해윤,김종대,Yoo, Hyo-Jeong,Park, Mee-Yeon,Choi, Hae-Yun,Kim, Jong-Dae 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3
Objectives : The object of this study was to obtain accurate information (single oral dose toxicity) of Lonicerae Flos (LF; Dried flower bud parts of Lonicera japonica Thunb (Caprifoliaceae)), which has traditionally been used in Korean medicine for treating various inflammatory diseases. Methods : In order to observe the 50% lethal dose (LD 50), approximate lethal dosage (ALD) and target organs, test articles were once orally administered to female and male ICR mice at dose levels of 2,000, 1,000, 500 and 0 (control) mg/kg (body weight.). The mortality and changes on body weight, clinical signs and gross observation were monitored for 14 days after single oral treatment of LF aqueous extracts with organ weights and histopathological observations of 12 types of principle organs. Results : 1. After single oral treatment of LF aqueous extracts, we could not find any mortality and toxicological evidences up to 2,000 mg/kg treated group, the limited dosages in rodents at body and organ weights, clinical signs, gross and histopathological observations. 2. Slight diarrhea was detected in most mice treated with 2,000 mg/kg of LF aqueous extracts and male mice of LF aqueous extracts 1,000 mg/kg within 2 days after end of treatment, respectively. Conclusion : The results obtained in this study suggest that the LD 50 and ALD of LF aqueous extracts in both female and male mice after single oral treatment were considered as over 2,000 mg/kg because no mortalities were detected up to 2000 mg/kg, the highest dose recommended by KFDA and OECD. However, we also observed the possibility of digestive disorders like diarrhea when over 1,000 mg/kg of LF aqueous extracts were administered in the present study.
유효정 ( Hyo-jeong Yoo ),주선호 ( Seon-ho Joo ),하지연 ( Ji-yeon Ha ),홍장의 ( Jang-eui Hong ),류관희 ( Kwan Hee Yoo ),나스리디노프아지즈 ( Nasridinov Aziz ) 한국정보처리학회 2016 한국정보처리학회 학술대회논문집 Vol.23 No.2
본 연구는 스마트폰 사용자가 응급상황에 처했을 때 사용자의 정확한 위치 정보를 응급 구조 센터에 전달할 수 있는 방법을 개발함에 목적을 둔다. 사고의 경우 실외 뿐만 아니라 실내에서 많은 사고가 발생하는데,일반적으로 위치 정보를 획득에 사용되는 GPS 의 경우는 실내 위치를 정확하게 파악하기 어렵기 때문에 구조를 지연시키는 문제를 야기한다. 본 연구는 이러한 상황들을 방지하기 위해 GPS 와 와이파이,블루투스를 각각 이용한 삼각 측량법을 통해 실내의 위치정보를 측정하고 더 나아가 압력센서를 통해 사용자의 위치를 3 차원적으로도 탐색한다. 실험 결과,GPS 를 이용하는 것보다 블루투스를 이용하는 것이 더 정확한 실내 정보를 탐색하는 것을 알 수 있었다. 또한 압력계를 통해 고도를 측정함으로써 건물 내부에서 사용자의 수직적 위치를 측정할 수 있었다. 이러한 결과는 위도 경도의 정확한 정보와 함께 고도에 대한 예측을 가능하게 함으로써 보다 정확한 실내 위치 정보를 획득하여 골든 타임을 확보하는데 도움이 될 것으로 보인다.
한(韓).양방(洋方) 겸치(兼治)로 치유된 폐결핵 환자 1례
장수영,유효정,윤경민,임은영,신현철,Jang, Soo-Young,Yoo, Hyo-Jeong,Yoon, Keong-Min,Im, Eun-Young,Shin, Hyeon-Cheol 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.1
Objective : This study was designed to evaluate the treatment effects and the prevention of side effects from antituberculosis drugs by using oriental medicine on a pulmonary tuberculosis patient. Methods : The clinical data was analyzed on a patient with pulmonary tuberculosis whose main symptoms were general weakness, anorexia, weight loss, tachycardia, night sweats, fever, coughing and chest pain. The patient was treated from June 17, 2008 to April 1, 2009, using herbal medicine (Cheongpyebyeolgab-tang) with antituberculosis drugs. Results : After treatment, the symptoms disappeared faster than with western medicine treatment only. Laboratory examinations and radiograph impressions also improved. No side effects of the antituberculosis drugs were noted. Conclusions : This suggests that oriental medicine therapy is effective for pulmonary tuberculosis and prevents the side effects of the antituberculosis drugs.
경추통에 대한 근 에너지 기법의 효과 : 체계적 문헌고찰
손부경(Bu-Kyung Son),유효정(Hyo-Jeong Yoo),금지혜(Ji-Hye Geum),이정한(Jung-Han, Lee),하원배(Won-Bae Ha) 척추신경추나의학회 2020 척추신경추나의학회지 Vol.15 No.1
Objectives : The purpose of this study was to provide a clinical evidence base for the effectiveness of the muscle energy technique(MET) for cervicalgia. Methods : We conducted a search of 10 electronic databases up to April 2019. Randomized controlled trials (RCTs) that performed the MET for cervicalgia were included. The risk of bias was assessed using the Cochrane risk of bias (RoB) tool. Results : Six RCTs met the inclusion criteria. The literature review of these studies showed favorable results for the use of the MET in comparison to other manual medicines. Conclusions : In 6 RCTs, we found that the MET was effective in cervicalgia treatment. However, most of the included studies had an unclear risk of bias. Therefore, well-designed RCTs are necessary to obtain a higher evidence level of the MET use in cervicalgia.