다중 중첩-합 구조에 기반한 개선된 시간 영역 엘리어싱 제거 필터 뱅크

유철재,김형명 한국통신학회 2001 韓國通信學會論文誌 Vol.26 No.8

오디오 부호화 시스템에 널리 쓰이는 시간 영역 엘리어싱 제거(TDAC) 필터 뱅크의 성능 개선을 위하여, 다중 중첩-합 구조를 바탕으로 한 개선된 TDAC 필터 뱅크를 제안하였다. 제안된 구조는 필터 뱅크의 분해 부분과 합성 부분 사이에서 발생하는 양자화 잡음의 효과를 줄이도록 제안되었다. 모의 실험을 통해 같은 양자화 비트 수를 사용하는 경우에 제안한 시스템이 SNR 측면에서 보다 나은 성능을 나타냄을 보였으며, 망 전송 데이터 양을 같게 한 경우에도 제안한 시스템이 더 적은 데이터 양의 블록 단위를 가질 수 있으므로 데이터 망의 혼잡 제어에 있어 보다 유리할 수 있음을 보였다.

자가혈당측정, 왜 필요한가

유철재 사단법인 한국당뇨협회 1993 당뇨 Vol.42 No.-

담관결석증이 동반된 담도회충증 1예

주봉덕,유철재,이헌영 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

Biliary ascariasis results not only in biliary tract disease, but also in secondary stone formation, hemorrhage into biliaty tract, acute cholecystitis, biliary perforation, invasion to pancreatic duct, pancreatitis, he%atitis, and liver abscess. In recent, we experienced a case of biliary ascariasis with concomitant biliary stones, which was identified by ultrasonogram percutaneous transhepatic cholangiography, and computed tomography, thereby reporting it herein with a review of literatures.

정상인에서 저혈당성 자극에 의한Catecholamines, Cortisol 및 Growth Hormone의 변화(抄)

김창국,유철재,성인환,노홍규,이복희 임상약학사 1993 臨床藥學 Vol.13 No.7

갑상선기능저하증의 임상적 고찰

노흥규,유철재 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

119 Cases of hypothyroidism were analysed in clinical features, laboratory data and pathologic findings, comparing with 21 healthy control group, since Jan. 1984 till Sept. 1985, at the Department of Internal Medicine, Chungnma National University Hospital. The results were as follows; 1. The age distribution was from 16 to 69 with the mean age of 36.9 years and M:F was 1:13.8. 2. The major presenting manifestations were easy fatigability, facial edema and weakness. Physical examination revealed diffuse goiter in 61.6% Major abnormalities were facial puffiness(16.1%), myxedema(6.2%) and thick tongue(2.7%), 3. The causes of hypothyroidism were primary (69.7%), post thyroidectomy (15.9%), post radiation (8.4%) and postpartum (5.9%). 4. The serum T_3, T_4 and TSH levels of the overt hypothyroid patients were 0.52±0.18mg/ml, 1.68±1.04㎍/dl and 40.53±9.82μU/ml respectively, and were significantly different to the normal controls. In the subclinical patients, the serum TSH level was significantly higher than normal controls. 5. The serum anti-microsomal Ab were positive in 71.8% and anti-thyroglobuline Ab was positive in 29.6%. 6. The pathologic findings in 44 cases revealed Hashimoto's thyroiditis in 70.4%, adenomatous goiter in 1630, papillary carcinoma in 6.8%, follicular carcinoma in 4.5% and subacute thyroiditis in 2.3%.

전현성 갑상선 기능저하증의 임상적 고찰

노흥규,이헌영,유철재,안원전 대한핵의학회 1986 핵의학 분자영상 Vol.20 No.1

Subclinical hypothyroidism can be defined as an asymptomatic state in which a reduction in thyroid activity has been compensated by an increased TSH output to maintain a euthyroid state. We analysed clinical features, laboratory data, and pathologic findings in 39 cases of subclinical hypothyroidism who were diagnosed at the Dept. of Internal Medicine, Chungnam National University Hospital from Aug. 1984 to June, 1985. 1) The age distribution was from sixteen to sixty-nine and mean age was 34.8. Peak incidence was in the 4th decade and 3rd, 5th, 6th decade in order. 2) The sex distribution showed female preponderance with a ratio of 18.5 to 1. 3) The major presenting manifestations were nonspecific ones such as fatigue, indigestion, and anorexia. 4) Physical examination revealed diffuse goiter in 47.6%. Major abnormalities were no gross abnormality (30.9%), nodular goiter and facial edema. 5) There was no significant difference of the basal serum T3 and T4 concentrations between subclinical hypothyroidism and normal controls (p〉0.05). 6) The basal serum TSH concentration of subclinical hypothyroidism (32.61±14.95 μU/ml) was significantly higher than that of normal controls (3.92±1.05 μU/ml) (p〈0.005). 7) Microsomal antibody was detected in 80.6% and thyroglobulin antibody was detected in 30%. 8) The pathologic findings in 26 cases revealed Hashimoto's thyroiditis in 76.9% (lymphocytic type, 34.6%; oxyphilic type, 26.9%; fibrotic type, 15.4%). The others were adenomatous goiter (15.4%), adenomatous carcinoma (3.8%) and subacute thyroiditis (3.8%).

녹용의 단백질가수분해 및 추출조건에 따른 특성 변화

김재화(Jae-Hwa Kim),유철재(Cheol-Jae Yoo),신경아(Kyung-A Sin),장세영(Se-Young Jang),박난영(Nan-Young Park),정용진(Yong-Jin Jeong) 한국식품영양과학회 2011 한국식품영양과학회지 Vol.40 No.1

녹용을 식품소재로 활용하고자 단백질 가수분해조건 설정 및 추출조건에 따른 품질특성을 조사하였다. 효소제 종류에 따른 영향을 조사한 결과 효소제 종류에 따른 pH는 차이는 없었으나, °Brix, 고형분 및 조단백질 함량은 ProteAX(A)에서 높게 나타났다. 효소제 A 농도에서는 0.5%(w/w)까지 °Brix, 고형분 및 조단백질 함량은 증가하였으며, 1.0%(w/w 이상에서는 큰 변화가 없었다. 가수분해 시간은 5시간까지 °Brix, 고형분 및 조단백질 함량은 증가하였으나 그 후 큰 변화가 없어 가수분해 시간을 5시간으로 설정하였다. 녹용에 효소 A와 C를 각각 0.5%(w/w)씩 혼합첨가 하여 60℃에서 5시간 가수분해할 때 고형분 및 단백질 함량이 가장 높게 나타났다. 상기 설정된 조건으로 가수분해 시킨 녹용가수분해물(DAH)과 대조구(DA)를 95℃ 상압조건(AP, 6~18시간) 및 120℃ 가압조건(UP, 15~60분)으로 각각 추출한 결과 pH는 효소처리 및 추출조건에 따른 큰 차이는 없었다. °Brix는 DA 1.5°Brix, DA-UP 및 DAH-AP에서는 2.2°Brix로 나타났으며, DAH-UP에서 60분 추출하였을 때 2.7°Brix로 가장 높게 나타났다. 또한 DAH-UP에서는 가용성 고형분 1.97%, 조단백질 함량 742.7 ㎎/100 g, 콜라겐 함량 498.8 ㎎/100 g으로 가장 높게 나타났다. 이상의 결과 가압추출조건이 녹용의 품질특성 향상에 더 효과적인 것으로 나타났으며, 향후 다양한 소재로 활용이 기대되었다. This study was conducted to investigate the proteolysis and extraction conditions of deer antler for application of food materials. ProteAX (A) was the most effective enzyme for proteolysis of deer antler and the proteolysis condition was 0.5% (w/w) for enzyme concentration and 5 hr for proteolysis time. The effect of mixing enzyme ProteAX (A)+KFEN 2 (C) treatment in 60℃, 5 hr was investigated; soluble solid and protein content were the highest with A 0.5% (w/w) and B 0.5% (w/w) concentration. Result for DAH (deer antler hydrolysate) and DA (deer antler) prepared with extraction in 95℃ atmospheric pressure (AP, 6~18 hr) and extraction under 120℃ pressure condition (UP, 15~60 min) after hydrolysis on preceding established condition descriptions indicated that difference in pH according to enzyme treatment and extraction conditions was not significant. Sugar content of DA was 1.5oBrix, DA-UP (under pressure) and DAH-AP (atmospheric pressure) were 2.2°Brix; the highest sugar content of 2.7°Brix was observed in DAH-UP for 60 min extraction. Also total free sugar, crude protein and collagen content were the highest in DAH-UP for 60 min recording at 1.97%, 742.7 ㎎/100 g and 498.8 ㎎/100 g, respectively. From these results, deer antler hydrolysate prepared with extraction under pressure was the most effective for functional characteristics enhancement. Hereafter, various practical uses of materials with enhanced characteristics of antler is expected.

급성 일산화탄소중독 환자에서의 혈청 Myoglobin 치

노흥규,신영태,한현석,유철재,안원전 대한내과학회 1986 대한내과학회지 Vol.30 No.2

The serum myoglobin level was measured in 20 patients with acute Co poisoning and 20 healthy control subjects. The patients were classified into 3 groups based on clinical severity of intoxication. Group I included 7 casea with mild symptoms such as headache or exertional dyspnea, group II included 6 cases with moderate degree symptoms such as nauea, vomiting, dizziness, or drowsy mental state and group III included 7 cases with severe symptoms such as stuporous or comatous mental state, convulsion, or shallow respiration and heart rate. The results were as follows: 1) The mean value of serum myoglobin of 20 normal healthy persons was 19.6±0.27ng/ml. 2) The serum myoglobin was slightly increased in mild cases (30.4±4.02) compared to control groups. And in patients with moderate to severe symptoms was showed each significant increase compared with normal controls. The more severe symptoms of acute CO poisoning were presented, the more elevated level of serum myogloin. (moderate; 141.6±55.9, severe; 707.1±1) 3) There was significant relationship between elevated myoglobin and leukocytosis. Hypoxemia was noticed in 3cases with marked elevated level of serum myoglobin. 4) There was no significant relationship between serum myoglobin and BUN and creatinine.

비갑상선 중증 질환에서 혈청 fT3와 rT3 의 변화에 관한 연구

이종화,노흥규,신영태,김주옥,유철재,문윤성 대한핵의학회 1985 핵의학 분자영상 Vol.19 No.1

Recently changes in thyroid physiology during acute and chronic medical illness were demonstrated. The serum fT₃, rT₃, T₄, T₃ fT₄ and TSH concentration were measured by radioimmunoassy method in 49 patients with critical illness and 10 normal subjects to assess the change of thyroid function in critical illness. The results were as follows; 1) The mean serum fT3 concentration was 6.68±1.05 pmol/ml in normal subjects while in patients with critical illness the serum fT3 concentration was significantly lowered to 1.55±1.15 pmol/ml (p〈0.001). 2) The mean serum rT3 concentration was 0.22±0.44 ng/ml in normal subjects and 0.42±0.37 ng/ml in patient with critical illness. The were was increment in critically ill patients as compared to normal subjects but no statistically significant difference (p〉0.05). 3) The mean serum T3 concentration was 1.24±0.25 ng/ml in normal subjects and 0.56±0.56 ng/ml in patients with criticial illness and there was significant difference in each other (p〈0.005). 4) The mean seT4, and TSH concentrations were 7.80±1.02 μg/dl, 1.26±0.39 ng/d1, 1.87±0.45 μU/ml in normal subjects respectively and 6.02±3.06 μg/dl, 1.46±0.80 ng/d1, 1.74±0.79 μU/ml in patients with critical illness and there wqs no significant difference between critically ill patients and normal subjects. 5) The ratio of mean serum concentration of fT₃ and rT₃ (fT₃/rT₃), 30.42±5.58 in normal subjects was significantly higher (p〈0.005) than the coresponding value, 6.39±6.76 in patients with critical illness. 6) The mean serum fT₃ concentration in expired cases (n=12) during admission was significant difference between expired and survived cases (p〈0.005). The mean serum rT3 concentration was 0.67±0.58 ng/ml in expired cases and 0.34±0.22 ng/ml in survived cases with significant difference (p〈0.005). Half of the cases who showed less than 3 μg/dl of serum T4 level were expired.

정상인에서 저혈당성 자극에 의한 Catecholamines, Cortisol 및 Growth Hormone 의 변화

노흥규,김창국,이복희,유철재,성인환 대한내과학회 1986 대한내과학회지 Vol.31 No.4

To characterize the hormonal responses to hypoglycemia in normal man, plasma catecholamines, serum cortisol. growth hormone, glucose, blood pressure and pulse rate were measured in insulin induced hypoglcemic states. The blood samples were taken before and 15, 30, 60, 90, 120 min after i.v. injection of 0.1U/B.W, kg regular insulin in 16 health volunteers after a l2-hours overnight fast. The results were as follows; 1) The basal serum glucose level was 74.4±8.0mg/dl(M±SD) which was decreased to 34.1±5.2mg/dl at 30min after insulin injection, returned to 84.7±10.5 mg/dl at 120 min after insulin injection. 2) The basal palsma norepinephrine level was 121.3±42.5pg/ml and there was no significant change with insulin injection(p$gt;0.05). On the other hand, the basal plasma epinephrine level was 43.8±14.7pgfml. A 5 fold increase in epinephrine to 214.4±47.4pg/ml was obseved 30min after insulin injection (P$lt;0. 05) 3) The basal serum cortisol level was 10. 92.1pg/dl which was increased significantly to 16.4±4.1 ㎍/dl(p<0.01) at 60 min after insulin injection. 4) The basal serum growth hormone level was 0. 5±0. 1ng/ml A 45-fold increase in growth hormone to 24.55.6ng/ml(p$lt;0.005) was observed 60 min after insulin injection. 5) The blood pressure levels remined unchanged and pulse rate showed mean increase to 10/min at 30min aft r insulin. The results of this study indicate that epinephrine playa a major role in the mctabo1ic response to insulin-induced hypoglycemia in normal man, growth hormone and cortisol may well function to argument the early hyperglycemic effect of epinephrine.