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RISS 인기검색어
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- 저자 : 유지영( Ji-Yong You) (검색결과 3 건)
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한국 성인의 비스페놀 A 노출과 비만과의 관련성 연구: 제2기 국민환경보건기초조사(2012-2014)
황문영(Moon-Young Hwang),이영미(Young-Mee Lee),정순원(Soon-Won Jung),홍수연(Soo-Yeon Hong),유지영( Ji-Yong You),박충희(Choong-Hee Park) 한국환경보건학회 2018 한국환경보건학회지 Vol.44 No.4
Objectives: Bisphenol A (BPA) has been extensively used in a variety of consumer products, resulting in widespread non-occupational human exposure. It is often detected in the human body. Studies have reported many health effects associated with endocrine and metabolic disruptions, including obesity, diabetes, hypertension, and cardiovascular diseases. This study was performed to explain the relationship between BPA exposure and obesity in the Korean adult population. Methods: The second stage of the Korean National Environmental Health Survey (KoNHES) was conducted from 2012 to 2014 with 6,478 persons participating. Using the results of the survey, we analyzed the exposure levels for BPA and the influence on obesity of BPA. Results: In model 1, the volume-based measure concentration of BPA, total, female and the 30s to 60s age group were positively related with BMI. In model 2, creatinine adjusted as a covariate and positive associations for BPA with BMI were observed in the female group and was marginally significantly associated in low body weight group. In model 3, creatinine adjusted (g/g-creatinine), BPA exposure, and BMI were positively related with sex, in females, and there was a marginally significant association with the low body weight group in the BMI categories. BMI was significantly associated with BPA in the female group in all three models. Conclusion: This study added further evidence that exposure to EDCs, include bisphenol A, is related with obesity among the general population. Given the environmental health concerns over BPA, it is necessary to develop comprehensive measures to reduce BPA exposure.
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전신마취 하의 복강경 질식 자궁적출술 수술시 가온요법 적용의 효과 비교
서용원,이윤정,박양숙,신정숙,조연숙,배상희,박순이,유지영,이정은,한금선 병원간호사회 2006 임상간호연구 Vol.12 No.1
Purpose: This study aimed to compare the effects of application of heating therapies using heated water circulation pads with those of heated irrigation fluid. Method: Patients were divided into a comparison group of 30 persons, a group of 30 persons to which heated water circulation pads were applied, and a group of 30 persons to which heated irrigation fluid was applied. The body temperature was measured every 15 minutes during operations in the esophagi at locations 1/3 above the lower ends thereof. Result: There was no significant difference in the decrease of body temperature during the operation, while there was a significant difference at the time of termination of anesthesia. There was no significant difference in the rate of occurrence of hypothermia. However, there was a significant difference in the time of arrival at the lowest body temperature. Conclusion: It is concluded that the application of heating therapies to LAVH patients under general anesthesia is desirable. The two heating therapies exhibit almost equivalent effects. Meanwhile, the heating therapy using heated irrigation fluid is advantageous in that the application thereof is easy and the cost of application is inexpensive.
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Gerbil의 전뇌허혈 모델에서 허혈증 경도 저체온에 의한 뇌의 Apoptosis 억제 효과
최승필,박규남,유지영,박승현,오동렬,이원재,천영호,김세경 대한응급의학회 2001 대한응급의학회지 Vol.12 No.1
Background: A brief episode of global forebrain ischemia produces selective and often extensive neuronal loss in several vulnerable brain structures. This cell death does not occur immediately, but is delayed for hours to days. This process is termed delayed neuronal death (DND). Recently, several reports have suggested that an apoptotic process may be involved in DND. The most effective treatment at present is intraischemic hypothermia. Thus, we designed this study to investigate whether intraischemic mild hypothermia could inhibit apoptosis following transient forebrain ischemia in gerbils. Methods: Twenty-four gerbils were divided into two groups based on intraischemic rectal temperature: 34℃(n=12) and 37℃(n=12). Two additional gerbils underwent a sham operation. Cerebral ischemia was produced by occluding both carotid arteries for 10 minutes. The DNA fragmentation in the gerbil hippocapal CA1 area was determined by using the TUNEL method, and the results for the normothermic and the hypothermic groups were compared at 1, 3, and 7 days following 10-min transient ischemia (n=4 for each time point, respectively). Results: 1. Percent dead hippocampal neurons were significantly decreased in the hypothermic group compared with the normothermic group at 1,3, and 7 days following transient ischemia (p$lt;0.05). 2. In the intraischemic normothermic group, TUNEL positive cells were first detected in the hippocampal CA1 at 3 days (1.9±0.6 cells/section), and the number was larger at 7 days following transient ischemia (127.8 ± 16.3 cells/section). 3. In the intraischemic hypothermic group, no TUNEL positive cells were detected in the hippocampal CA1 at 1,3, and 7 days following transient ischemia. Conclusion: The data suggest that delayed neuronal death following transient ischemia is, in part, apoptotic and that intraischemic mild hypothermia affords significant neuronal protection and prevents DNA fragmentation.
ScienceON
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