폐 격리증의 임상적 특성

오광택(Kwang Taek Oh),김연수(Yeon Soo Kim),김병철(Byung Cheol Kim),문두섭(Doo Seop Moon),이동석(Dong Suck Lee),이경상(Kyung Sang Lee),양석철(Suck Chul Yang),윤호주(Ho Joo Yoon),신동호(Dong Ho Shin),박성수(Sung Soo Park),이정희(Jung H 대한내과학회 1996 대한내과학회지 Vol.51 No.5

N/A Objectives: Pulmonary sequestration is a relatively rare congenital anomaly. It is a cystic mass of nonfunctioning lung tissue which lacks an obvious communication with the tracheobronchial tree and which receives all or most of its arterial blood supply from anomalous systemic vessels. It has a wide spectrum of various clinical manifestations. But high index of suspicion of sequestration with the aid of characteristic recurrent and longstanding symptoms, its location and invasive or non-invasive diagnostic tools is the key to early diagnosis and successful treatment. So we performed this clinical study to evaluate clinical symptoms and diagnostic methods of pulmonary sequestration. Methods: We reviewed eight cases of pulmonary sequestration seen during the period from 1982 to 1995 retrospectively to define the anatomical, clinical and radiologic features. Results: 1) The eight cases ranged in age from 11 to 35 years and show an even distribution within age decades. Sex ratio of male to female was a 1:1.67. 2) The presenting complaints were symptoms of local recurrent pulmonary infection. And also revealed unique chest pain or no any symptoms. 3) Plain X-ray findings were solitary nodules in three cases, pneumonic infiltration in two cases and cystic mass with air-fluid level, multiloculated cystic mass and solitary large cystic mass in each of the remaining three cases. 4) Preoperative diagnoses were possible in 5 cases and the other diagnoses were lung cancer in two cases and lung abscess in one case. 5) The seven cases were intralobar type and one case was extralobar type. Their location was in the lower lobe of the lung in seven cases and right upper lobe in one case. Among eight cases, the sequestrated lobe was located bilaterally in one case and the others were located unilaterally with a 2.5:1 Rt/Lt ratio. 6) Associated anomalies were esophageal cyst and bronchogenic cyst in two cases. 7) All cases were treated with lobectomy and extirpation without complication. Conclusion: We reviewed eight cases of pulmonary sequestration and its literature. These data reveal that pulmonary sequestration shows variable but characteristic clinical and radiological features. Therefore, a high index of suspicion about its characteristic clinical and radiologic features can provide us a change of early diagnosis and proper treatment of pulmonary sequestration.

소아기 류마티스 관절염의 임상적 특성에 관한 연구

오광택 ( Kwang Taek Oh ),정성수 ( Sung Soo Jung ),유태석 ( Tae Seok Yoo ),이제경 ( Je Kyung Lee ),송용호 ( Yong Ho Song ),정자헌 ( Ja Hun Jung ),고희관 ( Hee Kwan Koh ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),이인홍 ( In Ho 대한류마티스학회 1997 대한류마티스학회지 Vol.4 No.2

Objective: To investigate the clinical characteristics of Korean JRA and the possible profiles related to prognosis and to compare these data to pre-existing occidental reports. Methods: 140 cases of JRA patients were randomly selected from 1986 through 1995. Juvenile ankylosing spondylitis was excluded with the aid of modified New York criteria for ankylosing spondylitis. We used the classification of progression of rheumatoid arthritis (radiological stage III+IV/I+II+III+IV) as a index of prognosis. The study factors were sex, age, type, affected joints, degree of destruction of joint, anti-nuclear antibody (ANA), rheumatoid factor (RF), HLA-B27 and extra-articular manifestations. Chi-square test, One-way ANOVA test, and Pearson`s correlation coefficient were used as statistical methods. Results: Our study show results as follows: (1) Systemic onset type(11%) polyarthritis subset (66%), oligoarthritis subset (34%), oligoarthritis onset type(62%) sero(-)-HLA-B27(+) subset(66%), RF(+) subset(20%), not otherwise classified subset (14%) ANA (+)-chronic uveitis subset (0%), polyarthritis onset type(27%) RF(+) subset (66%), not otherwise classified subset(34%). (2) Sex ratio was M:F=1.8:1. (3) Age of onset was 11±3.6 years. (4) Affected joints were knee, ankle, hand in decreasing order of frequency. (5) Patients show seropositivity of RF in 31%, HLA-B27 in 54%, ANA in 8%. (6) Chronic uveitis was observed in 7 cases (5%) (all oligoarthritis onset type, M:F=6:1, age of onset 11±4.3 years, ANA(0%), HLA-B27(86%), 2 cases leading to blindness. (7) Destructive bone change was significantly more prominent in female(p<0.01), RF(+) (p<0.01), HLA-B27(-) (p<0.01), polyarthritis onset type (p=0.02 ). Conclusions: In this study, we obtained interesting results that are somewhat different from Occidental data in sex ratio(male dominance), age of onset(older age), profiles of HLA-B27(high positivity in spite of low HLA-B27 positivity in Korean (about 2.3%), low rate of destructive change), ANA (low positivity, older age of onset), chronic uveitis(low incidence, male dominance, older age of onset, high association with HLA-B27, not associated with ANA). This study suggests possible racial difference in clinical features of JRA. But for prove of racial difference, further multi-center trial and large scale epidemiological study should be done.

선박용 터보차져 원심압축기의 성능향상 개발

오종식,오군섭,유광택,Oh, Jong Sik,Oh, Koon Sup,Yoo, Kwang Taek 한국유체기계학회 2000 한국유체기계학회 논문집 Vol.3 No.1

선박용 디젤엔진에 정착되어 사용되는 기존의 터보차져 성능을 개량하기 위하여 압축기만의 수정개발을 수행한 결과를 요약하면 다음과 같다. (1) 터빈과의 싸이클 matching 작업을 통하여 기존의 압축기 성능에 비하여 $7\%$ 증가된 회전수와 $8\%$ 증가된 입구 공기유량으로 상향 조정되면서 효율의 큰 저하 없이 전압력비도 3.5 수준으로 증가되도록 설계점이 성공적으로 확정되었다. (2) 기존의 압축기 케이싱과 스크롤을 대부분 그대로 사용한다는 기하학적 제한조건하에서 3차원 공력 설계가 성공적으로 수행되었고, 설계된 임펠러는 3차원 압축성 난류 수치유동해석 과정을 통해 구체적인 내부 유동과 임펠러의 overall 성능을 확인하였다. (3) 터보차져 전용 시험리그에서 시제품을 성능시험한 결과, 전반적인 압축기의 성능곡선을 성공적으로 도출하였다. 대체적으로 전체 회전수별로 실험결과로 얻은 전압력비는 설계 예측치와 매우 잘 일치하는 모습을 볼 수 있었고, 단열효율의 경우, 실험치와 예측치가 서로 잘 일치하고 있었다. 설계의도대로 설계점에서의 압력비 상승과 유량의 증가 등은 만족스럽게 달성된 것으로 판단된다. (4) 베인디퓨져의 제작문제로 인하여 설계회전수에서의 surge와 choke margin이 설계의도와는 달리 좋지 않은 상태이다. 이는 본래 설계대로 베인디퓨져를 재제작하고 설치각의 크기를 조절함으로써 앞으로 진행될 추가시험에서 보완할 예정이다. Upgrade development of a high pressure ratio centrifugal compressor in marine engine turbochargers is presented. A new matched operating point at increased speed of rotation was determined through system cycle analysis using the exisitng test data of turbine performance. Under some severe restrictions for geometric parameters, the state-of-the-art methods of both aerodynamic design and CFD analysis were applied, in which only an impeller, a vaned diffusor and some part of casing wall were modified. Prototype hardware was fabricated and assembled for system performance tests. Excellent performance in pressure ratio and efficiency was obtained over whole speed region. Reduced surge and choke margin was, however, observed at design speed of rotation.

류마티스 관절염과 HLA-B27과의 연관성에 관한 연구

고희관 ( Hee Kwan Koh ),오광택 ( Kwang Taek Oh ),송용호 ( Yong Ho Song ),정자헌 ( Ja Hun Jung ),김태환 ( Tae Hwan Kim ),김동욱 ( Dong Yook Kim ),전재범 ( Jae Bum Jun ),정성수 ( Sung Soo Jung ),이인홍 ( In Hong Lee ),배상철 ( Sang 대한류마티스학회 1996 대한류마티스학회지 Vol.3 No.1

Objective: In rheumatoid arthritis(RA) patients, HLA-B27 has been mainly found with the same frequency as in the normal population. An increased frequency of HLA-B27 in RA has, however, repeatedly been found in northern Sweden and in Filand. The results concerning the association of HLA-B27 to the outcome of the disease have been contradictory in RA. In RA, the presence of HLA-B27 has shown to be a prognostic index for cervical spine subluxation. There has been no report regarding the association between RA and HLA-B27 in the Korean population. Methods: 188 patients with RA were randomly selected from the patients who were diagnosed at Rheumatism Center of Hanyang University Hospital from October 1994 to June 1995 to establish the frequency of HLA-B27 in RA and to investigate the possible influence and prognostic significance on clinical outcome including atlantoaxial subluxations. Results: The results were as follows: 1) HLA-B27 was present in 12.2% of the RA patients studied. The relative risk (RR) and etiologic fraction (EF) of HLA-B27 were 5.99 and 0.1019 respectively. 2) The rheumatoid factor was positive in 79.8% of the total patients, 73.9% in HLA-B27 positive patients, and 80.6% in HLA-B27 negative patients. HLA-B27 was not associated with the presence of rheumatoid factor in this study. 3) HLA-B27 was not associated with the duration of morning stiffness, Ritchie index, extraarticular manifestations, the number of swollen joints, ARA functional class, ESR. C-reactive protein, or hemoglobin. HLA-B27 was not associated with the positivity of ANA and antiperinuclear factor. 4) HLA-B27 was not associated with the positive rate of erosion and Steinbrocker class in peripheral joints. 5) Atlantoaxial subluxation was present in 13% of HLA-B27 positive patients and 17% of HLA-B27 negative patients. The involvement of atlantoaxial joint including narrowing of lateral facet joints was 26.1% in HLA-B27 positive patients and 20.6% in HLA-B27 negative patients. Subaxial subluxation was presented in only 1 case in HLA-B27 negative group of total patients. HLA-B27 was not associated with the cervical changes in RA. Conclusions: An increased freuency of HLA-B27 in RA patients was significantly found in Korea (RR=5.99, EF=0.1019). However, patients with HLA-B27 had a similiar clinical profile to patients without HLA-B27 and HLAB27 positivity did not further contribute to the severity with respect to clinical and laboratory variables or to radiological progression in peripheral joints or cervical spine.

전신성 홍반성 루푸스 환자에서 대장천공을 유발한 거대세포바이러스 대장염

오승일 ( Seung Il Oh ),이오영 ( Oh Young Lee ),오광택 ( Kwang Taek Oh ),이재형 ( Jae Hyung Lee ),박재홍 ( Jae Hong Park ),엄완식 ( Wan Sik Uhm ),이혜순 ( Hye Soon Lee ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),정성수 ( Sung 대한류마티스학회 2003 대한류마티스학회지 Vol.10 No.1

Cytomegalovirus (CMV) infection is a common human viral infection, affecting 40% to 100% of normal adult, especially in the immune compromised patients. CMV infection can produce variable gastrointestinal (GI) diseases in healthy adults, but can cause severe life-threatening illness involving many organs, including lung, retina, central nervous system, liver and GI tract in immunocompromised host. We experienced CMV colitis with colon perforation in a SLE patient during low dose steroid and azathioprine therapy, and she recovered after medical treatment without surgical interventions. A 33-year-old woman was diagnosed as SLE 7 years ago and treated with low dose, immunosuppressive therapy during 6 years. She complained of a severe abdominal pain and hematochezia. She was diagnosed as CMV colitis with colon perforation by pathologic, immunologic and image studies. After medical treatment, such as intravascular ganciclovir, there was progressive medical improvement, but has been a recurrent CMV colitis with lower GI bleeding.

살균에 박리 및 분산 기능이 추가된 친환경살균제에 대한 역삼투(RO)막에서의 효과 검증 연구

박덕준(Duk Joon Park),오은정(Eun Jung Oh),김성한(Sung Han Kim),안광택(Kwang Taek Ahn) 대한환경공학회 2016 대한환경공학회지 Vol.38 No.9

살균기능에 박리와 탈리기능 추가된 비유독물인 친환경살균제를 역삼투(RO)막 부착된 유기물 등 오염물질 제거를 위하여 현장 적용시 역삼투막 차압증가 도달시간을 기준 적용시 평균 93.0%의 개선효율을 보였다, 또한 친환경살균제를 사용한 역삼투막을 Autopsy한 결과, 무기 및 유기오염의 비율이 기존살균제에 비하여 친환경살균제를 사용한 역삼투막이 유기오염의 비율이 적은 것으로 조사됨에 따라 친환경살균제의 바이오필름 제거(분산, 박리) 및 살균력이 기존 약품보다 우수한 것으로 확인되었다. Eco-friendly biocide that do not have noxious chemicals, have a role of disinfection adding of dispersion and strengthening peer power on RO membranes surfaces. Eco-friendly biocide show an 93% improvement of differential pressures arrival time. Also, eco-friendly biocide’s Autopsy result show less the percentage of organic pollutants than currently in using biocide. Adding dispersion & peeling strength power to remove the microorganisms is upgrading. Eco-friendly biocide that have a dispersion and peering power is non-toxicant chemicals and is safe for user.

응급 내과환자의 저나트륨혈증

정자헌(Ja Hun Jung),손동현(Dong Hyun Sohn),박준용(Joon Yong Park),오광택(Kwang Taek Oh),한동수(Dong Su Han),양석철(Suck Chul Yang),손주현(Ju Hyun Sohn),김순길(Soon Kil Kim),김호중(Ho Jung Kim) 대한내과학회 1996 대한내과학회지 Vol.51 No.4

N/A Objectives: Hyponatremia is the most common finding of electrolyte disorder in patients admitted to medical ward. It is suggested that the prognosis of patients with hyponatremia is worse than that with normal sodium concentration in morbidity and mortality. We performed the study to evaluate the incidence and cause of hyponatremia in inpatients admitted to medical ward via emergency room with prospective study. Methods: Hyponatremia was defined as a serum sodium concentration equal to or less than 134 mEq/L. A total 225 medical patients were prospectively studied for 45 days. Other chemistry and electrolytes of blood and urine were determined within 24 hrs following admission. Results: 1) Of medical inpatients through emergency room, hyponatremia was detected in high frequency (16%) and mild hyponatremia (125-134 mEq/L) was showed in 90% or more. 2) The most common cause of hyponatremia was decreased effective circulating blood volume group (76%), and its common underlying disease was liver disease. 3) Compared to other groups, the group with decreased effective circulatory volume showed significant decrease in spot urine sodium concentration, fractional excretion of uric acid and serum creatinine concentration. 4) There was no correlation between serum concentration of hyponatremia and other parameters associated with it. As it was corrected, no significant simultaneous changes on BUN and serum uric acid concentration was noted. Conclusion: Interpretation of this data depend on not decreased circulatory volume but also other compounding factor as production and excretion of which is related to underlying variable disease.

국내 폐효모균증의 임상적 특징

문두섭 ( Doo Seop Moon ),유정수 ( Jeong Soo Yoo ),김정미 ( Chung Mi Kim ),김연수 ( Yeon Soo Kim ),김성민 ( Seung Min Kim ),오광택 ( Kwang Taek Oh ),손장원 ( Jang Won Sohn ),양석철 ( Seok Chul Yang ),윤호주 ( Ho Joo Yoon ),신동호 ( 대한결핵 및 호흡기학회 1997 Tuberculosis and Respiratory Diseases Vol.44 No.5

우리 나라 농장 사육 타조 알의 난질 조사

송광택,오홍록 충남대학교 농업과학연구소 2002 농업과학연구 Vol.29 No.1

The fresh eggs of African ostrich in Korea were used in this study to investigate their interior and exterior quality characteristics. In ostrich egg shape characteristics, long and short length were measured as 15.1∼16.1 ㎝ and 12.1∼13.6 ㎝, respectively. The egg shape index was calculated as 81.0 and the egg shell showed a more gloss white in color than that of hen egg. Calculated breaking strength of egg shell and egg shell surface based on the equation were 41.155 ㎏/㎤ and 804.7 ㎠, respectively. Average egg shell thickness including egg shell membrane was 1.89 ㎜ and there are no differences among parts of the shell. The egg shell membrane thickness was 0.10 ㎜ showing relatively thick in equator compared with that of blunt end. The average number of egg shell pores was counted as 19.7/㎠ showing relatively high number of egg shell pores at point end and the total number of egg shell pores in an egg was estimated as 15,241. The relative portion of each parts based on egg weight was estimated as 25.1% for egg york, 58.2% for egg white, 16.7% for egg shell and the ratio of egg yolk to egg white(Y/W) was 0.43. The average diameter and the average height of ostrich egg white were 19.7 ㎝ and 13.2 ㎜, respectively. Calculated the H.U (Haugh Unit) was -69.7 and the pH was 8.3. In ostrich egg yolk, the diameter, the height, the egg yolk index, and it's pH were calculated as 14.4 ㎝, 29.4 ㎜, 0.20, and 6.6, respectively. And the egg yolk color showed a more thin in yellow chroma compared with that of hen egg as due to it's thicker membrane.

DNA 분석법에 의한 한우고기 판별

오홍록,이창수,상병찬,송광택 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.1

This study was deal with the development of breed-specific DNA marker which is able to identify Hanwoo and European cattle breeds(Non-Hanwoo) meat. Genetic differentiation between Korean cattle(Hanwoo) and European cattle breeds was examined by Random Amplified Polymorphic DNA(RAPD) analysis. The RAPD patterns were identical among Non-Hanwoo, such as Holstein, Hereford. Aberdeen Angus. Brown Swiss. Limousin or Simmental. but the above pattern was different from that of Hanwoo. All bands detected in the Hanwoo samples were observed in Non-Hanwoo cattle samples, but one of the common bands found in samples was not detected in the Hanwoo samples. The band(1.4kb) may be useful as a marker for identifying a meat of Hanwoo from imported cattle meat. Actually, the detection of the DNA marker was tested by DNA analysis with 929 samples which were prepared from bloods of 673 Hanwoo cattles and 141 Holstein cattles, from 115 imported cattle meats. The DNA marker was absent in 644 of 673 Hanwoo cattles (96%) but present in 245 of 256 Non-Hanwoo cattles (95%). These results show that the DNA marker is effective to characterize Hanwoo and Non-Hanwoo meat by its detection. This DNA marker, however, was not useful in detecting unwanted crossbreeding between two cattle breeds, because the band pattern in hybrid cattle shows one of two band patterns in Hanwoo and Non-Hanwoo.