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      • KCI등재후보

        신장질환에서의 세포성면역반응

        오강열(Kang Yeal Oh),강성귀(Sung Kyew Kang) 대한내과학회 1987 대한내과학회지 Vol.32 No.4

        N/A This study was undertaken to investigate whether cell-mediated immunity are affected by renal diseases. Thirty six patients with lipoid nephrosis and chronic proliferative glomerulonephritis, and 16 controlled subjects were studied by summation of delayed-cutaneous hypersensitivity response to 8 test antigens such as Tetamas, Diphtheria, Group C-streptococcus, Tuberculin, Glycerim, Candida albicans, Tricophyton mentaprophytes and protes mirabilis. The total average diameter of all positive reaction in controlled subjects was 15.34±2.03 mm. Of the 16 subjects, negatvie reaction was observed in 3 (18.8%). In patients with lipoid nephrosis, during relapsing phase the total average diameter of all positive reactions was 5.38±2.48 mm. being significantly lower than that of normal subjects. Negative reaction was observed in 9 of 10 patients (90%). The total average diameter of all positive reactions in patients with lipoid nephrosis in the remission phase was 13.09±1.64 mm showing no significant difference in total average diameters between control and remission phase group. Negative reaction was observed in 1 of 9 patients (11.1%). In chronic proliferative glomerulonephritis patients with the nephrotic syndrome, the total average diameter was 10.25±2.20 mm, showing no significant difference with control group, Negative reaction was observed in 3 of 10 patients (30%). The total average diameters of all positive reactions in patients with chronic proliferative glomrulonephritis without nephrotic syndrome was 12. 93±3.48 mm, showing non significant difference in total average diameters between control and patients group. Negative reaction was observed in 2 of 7 patients (28.56%) This study suggests lipoid nephrosis impairs cell mediated immunity, and the impairement of delayed hypersensitivity reaction seems to be related to clinical stages of nephrosis.

      • 이상단백혈증을 동반한 혈관면역아구성 림프선증 1예

        문우성,이동근,오강열,장성강,최호열,김상호 의과학연구소 1992 全北醫大論文集 Vol.16 No.3

        A 25 year-old male with angioimmunoblastic tyrnphadenophthy(AILD) was reported with review of literatures. Clinically, he complained of generaized tyrnphadenopathy, fever, cutaneous rash, and splenomegaly and serum protein electroporesis revealed polyclonal gammopathy. Histologic finding of excised Iymph node were characterized by 1) loss of nodal architecture and infiltration of immunoblasts, plasma cells, Iymphocytes and eosinophils, 2) prominent proliferation of arborizing blood vessels, and 3) deposit of PAS-positive amorphous materials in the interstitium. After 3 weeks of prednisolon therapy, remarkable improvement of his clinical was occurred and alive 20 months after diagnosis.

      • KCI등재후보

        장기간 혈액투석 환자에서 발생한 후천성 신낭종 1 예

        최은영,강성귀,김해강,오용일,오강열 대한내과학회 1986 대한내과학회지 Vol.31 No.4

        Long-term hemodialysis and renal transplantation have led to a significant prolongation of life in patients with uremia of chronic renal disease. These patients are at risk of development of renal cystic disease and renal neoplasms. Identification of cysts and solid tumors in the kidneys of long-term dialysis patients can be preformed easily and correctly by abdominal CT scanning. Here we report one case of acquired renal cystic transformation in a long-term dialysis patient. He is 58-year-old man with chronic renal failure secondary to diabetic nephropathy. He has been treated by hemodialysis for 5 years. Physical examinations were negative. The urea nitrogen was 68.9 mg%, the creatinine 13.1 mg%, the sodium 137mEq/l, the potassium 6,6 mEq/l, the phophorus 5.9 mg%, and the hemoglobin 8.8g%. We found multiple cystic lesions in both kidneys by abdominal CT scanning on January 1986.

      • KCI등재후보

        폐결핵환자에서 혈청 Angiotensin-Converting-Enzyme(ACE) 활성도의 변동에 관한 연구

        최은영,이양근,유관희,안관용,오강열,박성희 대한내과학회 1986 대한내과학회지 Vol.30 No.1

        Angiotensin converting enzyme which is thought to be originated from the epitheloid cells with area of series phagocytosis reported to be inreasced in sarcoidosis, Gaucher`s disease, chronic renal failure, diabetes mellitus and leprosy, The serum ACE activity was assayed spectrophotometrically in 28 pulmonary tuberculosis patients and 13 bronchial asthma patients to investigate ACE activity can be used as an index of tuberculosis activity. The results were as follows: 1) The serum ACE level was higher in patients with active pulmonary tuberculosis (3.4348±3.2079) than in normal control group(1.4026±2.0034) (P0.05). 2) On cheat roentgenographic findings, the serum ACE level was higher in patients of active minimal pulmonary tubereulosis than those of the moderate advanced pulmonary tuberculosis. 3) Forced vital capacity showed significantly strong negative correlation with the serum ACE level(r=-0.4133) while no significant correlation was found between serum ACE level and other pulmonary diseases. It can beuggested that activity of serum ACE is useful parameter to indicate activity E. progress of pulmonary tuberculosis.

      • 회장에 발생한 아니사키스증 1례

        김주헌,조성국,조백환,오강열,이동근,최호열,김상호 의과학연구소 1993 全北醫大論文集 Vol.17 No.1

        Human anisakiasis is a disease caused by the opportunistic infestation of the third stage larvae of family anisakidae. It is charaterized by the invasion of the ingested larvae to the gastrointestinal wall. causing the various degree of clinical symptoms and inflammatory changes. While gastric anisakiasis is commonly diagnosed by endoscopic techinique, intestinal anisakiasis is rare because it is less common and the clinical and radiologic pictures are poorly understood. The authors repore a case of human anisakiasis involving the distal ileum in 50-year-old woman sho was incidentally found to have the lesion during an operation.

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