동합금 가두리 망 사육어류, 조피볼락(Sebastes schlegeli)의혈액 성상과 중금속 축적률

양성진 ( Sung Jin Yang ),전제천 ( Je Cheon Jun ),박정준 ( Jung Jun Park ),명정인 ( Jeong In Myeong ),신윤경 ( Yun Kyung Shin ) 한국어류학회 2014 韓國魚類學會誌 Vol.26 No.3

동합금 가두리망에 6개월간 사육한 조피볼락을 대상으로동합금 가두리 망에서 유출되는 물질이 어류의 생존, 성장및 건강도에 미치는 영향을 조사하였다. 대조구와 실험구간의 생존율과 성장률 그리고 혈액 성상은 유의한 차이가 없었으며(P/0.05), 간세포의 형태 및 간 조직 내에 존재하는 모세혈관과 담관의 구조가 특이적인 차이를 보이지 않았다. 구리와 아연 축적량은 실험 초기에 비해 증가하였지만 실험구와 대조구 간의 차이가 없었으며 허용기준치에 비해 매우 낮게 나타나 본 연구에 사용된 동합금망은 어류의 생존, 성장 및 건강도에 영향을 끼치지 않는 것으로 여겨진다. The effect of substances discharged from copper alloy mesh on the survival rate, growth, and health status of Sebastes schlegeli was investigated. Survival rate of experimental group was 10%higher than control group. There was no significant difference in weight gain and SGR between control group and experiment group (P/0.05). Glucose concentration was lower in the experimental group than that in the control group. GOT and GPT contents did not show significant difference during experiment except for the early three months of experiment (P/0.05). Ammonia concentration had not significantly changed in the experimental group, but it had increased until four months of experiment and then decreased afterwards in the control group. TCHO had decreased in the experiment group compared with that of control group. Copper and zinc contents had increased as compared with those in the initialst age of experiment with no significant difference between experiment group and control group(P/0.05). Histological analysis for the liver revealed that liver tissues were not particularly different from those in control group. There were no significant differences in survival rate, growth, and hematological characteristic between control group and experiment group (P/0.05). Though copper and zinc were accumulated as compared with those during the initial stage of experiment, the levels were lower than permissible levels for copper and zinc. As a result, copper alloy mesh would not adversely affect on the survival rate, growth, and health status of fishes.

활어 수송용 컨테이너에 수용된 조피볼락(Sebastes schlegeli)의 생존율, 혈액성상, 혈구 사멸률 및 조직학적 변화

양성진 ( Sung Jin Yang ),전제천 ( Je-cheon Jun ),민병화 ( Byung Hwa Min ),박노백 ( Noh Back Park ),강희웅 ( Hee Woong Kang ) 한국수산과학회(구 한국수산학회) 2018 한국수산과학회지 Vol.51 No.4

This study investigated the survival rates and physiological responses of Korean rockfish, Sebastes schlegeli, in live fish containers (8℃, 33 psu) for 18 days. The survival rate was 99% and 97% in the control and experimental groups, respectively. Hematocrit and hemoglobin did not differ significantly between the control and experimental groups. Glucose and cortisol rose immediately on the first day of containment, but both gradually normalized. Aspartate aminotransferase and alanine aminotransferase did not differ significantly between the two groups after recovery. NH3 continued to rise after the first day, but decreased to a level not significantly different from that of the control group during the recovery period. Plasma ions and osmolality did not change abnormally. The hemocyte population was not significantly different from that of the control. The ratios of apoptotic and necrotic cells indicated no specific variation in hemocyte viability. The histological changes in the skin and gills were not significantly different from those seen in the control. The experimental data obtained in this study suggest that live fish containers may be used to transport Korean rockfish without significantly affecting their physiology or survival.

적정 수송 조건하의 활어용 컨테이너 내 참전복(Haliotis discus hannai)의 생존 및 생리 변화 구명

양성진 ( Sung Jin Yang ),전제천 ( Je-cheon Jun ),강희웅 ( Hee Woong Kang ),박노백 ( Noh Back Park ),민병화 ( Byung Hwa Min ) 한국수산과학회(구 한국수산학회) 2018 한국수산과학회지 Vol.51 No.3

This study investigated survival rates and physiological responses in Pacific abalone (Haliotis discus hannai) to 18 days of containment in live fish containers (8℃, 34 psu). The investigation was divided into three periods: before, during, and recovery after transportation. The overall survival rate was greater than 99%. Glucose, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) rose immediately on the first day of containment, but then gradually returned to normal levels. NH₃ continued to rise after the first day, but during the recovery period it decreased to a level not significantly different from that of the control group. Na⁺ and osmolality did not show any abnormal changes. After recovery, superoxide dismutase (SOD) was not significantly different from control. Abalone in the experimental group had lower glutathione reductase (GR) than control. The hyalinocyte ratio fell immediately after confinement, but then gradually increased until it reached a normal level. The ratios of apoptotic and necrotic cells indicated no specific variations in hemocyte viability. Histological changes in the epidermal layer and muscle layer of the foot were not significantly different from those seen in the control group. The experimental data obtained in this study suggest that live fish containers may be used for transport of Pacific abalone withouts ignificantly impacting their physiology or survival rates.

임신성 당뇨 진단 기준의 고찰

양성천 ( Seong Cheon Yang ),김행수 ( Haeng Soo Kim ),양정인 ( Jeong In Yang ),이희종 ( Hee Jong Lee ),안상태 ( Sang Tae Ahn ),서성석 ( Seong Sug Seo ),유희석 ( Hee Sug Ryu ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.11

목적: 임신성 당뇨의 진단기준을 낮추는 것이 미치는 효과를 밝히고자 하였다. 연구 방법: 임신 24-28주에 시행한 50 gm 경구 당부하검사상 혈장 혈당치가 130 mg/dl 이상인 산모에게 임신 28-32주에 100 gm 경구 당부하검사를 시행하였다. Carpenter-Coustan과 NDDG의 임신성 당뇨에 대한 진단기준을 적용하여, 대조군: 50 gm 경구 당부하검사상 정상군 (n=268), Borderline 군: Carpenter-Cousta Objective: To determine the effect of lowering the cutoff values of 3-hour oral glucose tolerance test (OGTT) for gestational diabetes mellitus (GDM). Methods: Patients with an abnormal 50 gm glucose challenge test (GCT) of more than 130 mg/dL at 24-28 we

조피볼락(Sebastes schlegeli)의 장거리 수송을 위한 적정 수온 및 염분 조건 탐색

양성진 ( Sung Jin Yang ),이정용 ( Jeong Young Lee ),전제천 ( Je-cheon Jun ),명정인 ( Jeong-in Myeong ),민병화 ( Byung Hwa Min ) 한국수산과학회(구 한국수산학회) 2017 한국수산과학회지 Vol.50 No.1

The optimum temperature and salinity for long-distance transportation of rockfish Sebastes schlegeli were investigated by assessing hematological characteristics and hemocyte mortality. The possible effects of the interaction of temperature and salinity on these attributes were also investigated. No significant difference was found in hematocrit and hemoglobin among experimental conditions. Glucose levels were highest in fish exposed to salinities of 34 psu (4℃), 18 psu (4-6℃) and 10 psu (4-8℃). Cortisol levels were elevated in the lowest temperature group (4℃), but upper limits decreased with decreasing salinity. AST and ALT increased as temperature decreased at salinities lower than 26 psu. The ratio of living cells was 99.0-99.6% in all experimental groups. The percentage of necrotic cells was highest in fish exposed to salinities of 34 psu (4℃), 18 psu (6-8℃), and 10 psu (4-8℃). The percentage of necrotic cells decreased significantly as temperature and salinity decreased, indicating that both salinity and the interaction of salinity and temperature affected cell necrosis.

참전복(Haliotis discus hannai)의 장거리 수송을 위한 적정 수온 및 염분 조건 탐색

양성진,민병화,이정용,전제천,명정인,Yang, Sung Jin,Min, Byung Hwa,Lee, Jeong Young,Jun, Je-Cheon,Myeong, Jeong-In 한국해양생명과학회 2017 한국해양생명과학회지 Vol.2 No.2

This study was carried out to investigate the stress response of pacific abalone exposed to various water temperatures (4, 6, 8, and 10℃) and salinities (26, 30, and 34 psu) for 7 days, with the aim of finding optimum conditions for long-distance ocean transport of pacific abalone. At the end of the experiments, the survival rate was ranged from 98.7~100% at 8 and 10℃ but dropped to 25~55% at 4℃ in all salinity levels. The levels of SOD and glutathione in hemolymph were significantly higher at 4 and 6℃ than the control in all salinity groups, indicating that these temperatures induce severe stress in pacific abalone. It was found that THC was lowest at 6℃ in the 26 psu groups. The study showed that the hemocyte of pacific abalone populations mostly consisted of blast-like cells and hyalinocytes with the ratio of hyalinocytes being significantly lower at 4 and 6℃ than the other temperatures in the 26 psu groups. Percentages of apoptotic cells and necrotic cells were higher in the 26 psu group and 4 and 6℃ temperature groups. These results explicit that pacific abalone was exposed to greater stress at 26 psu and at 4 and 6℃ but experienced no significant higher stress at 30 and 34 psu and 8 and 10℃. It was therefore concluded that the optimum temperature and salinity for the long distance transport of pacific abalone range from 8~10℃ and 30~34 psu, respectively.

HELLP 증후군의 임상적 고찰

안상태 ( Sang Tae Ahn ),김행수 ( Haeng Soo Kim ),양정인 ( Jeong In Yang ),오준환 ( Joon Hwan Oh ),한기수 ( Ki Su Han ),양성천 ( Seong Cheon Yang ),오기석 ( Kie Suk Oh ) 대한주산의학회 2001 大韓周産醫學會雜誌 Vol.12 No.2

자궁외임신의 최근 8년간의 임상적 고찰

박성호 ( Sung Ho Park ),나연식 ( Yon Sik Na ),정지윤 ( Ji Yoon Jung ),양성천 ( Seong Cheon Yang ),최수란 ( Su Ran Choi ),김성주 ( Sung Joo Kim ),장봉림 ( Pong Rheem Jang ),권용일 ( Yong Il Kwon ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.2

목적: 자궁외임신에 대한 임상 및 역학적 특성을 분석하고 그 조기진단과 적정한 치료법을 확인하기 위해 본 연구를 시행하였다. 연구 방법: 2000년 1월부터 2007년 12월까지 한림대학교 의료원의 자궁외임신 환자의 의무기록지를 조사하였다. 결과: 자궁외임신의 빈도는 13.6개의 분만당 1건이었고 호발 연령은 26~30세였다(29.5%). 위험인자는 과거 복부나 골반수술 병력(37.0%), 인공유산 병력(30.8%) 골반염 병력(12%), 난관불임술 병력(9.6%) 순이었다. 증상은 무월경(88.7%), 하복통(81.2%), 질출혈(60%) 순으로 나타났으며, 증상 발현은 마지막 생리시작일 후 6~8주가 47%로 가장 높은 빈도를 보였다. 혈색소는 10 gm/dL 이상이 79%였고 8 gm/dL 이하가 3.9%였다. 발생부위는 난관에 89%, 자궁각에 7.2%, 난소에 1.1%, 자궁경부에 2.7%였다. 수술은 복강경이 755예(71.6%), 개복술이 273예(25.9%), 소파수술이 26예(2.5%)에서 행해졌다. 수술 시 난관 절제가 82.4%로 가장 많았고, Methotrexate(MTX) 치료는 13예 (1.21%)에서 성공적으로 행해졌다. 결론: 자궁외임신의 조기진단은 혈청 β-hCG와 질초음파를 함께 이용하는 것이 가장 유용하다고 생각되며 치료는 복강경수술이 개복술에 비해 입원기간 및 합병증을 낮출 수 있어 향후 치료에 더욱 중요한 역할을 하리라 생각된다. Objective: The study was designed to ascertain a proper method of early diagnosis and treatment of ectopic pregnancy by analyzing its clinical and epidemiological characteristics. Methods: The medical records of patients who were diagnosed to ectopic pregnancy at Hallym medical center during the period from January 1, 2000 to December 31, 2007 have been reviewed. Results: The incidence of ectopic pregnancy was 7.3% (1,067) out of 14,519 deliveries. The most frequent age group was 26~30 (29.5%). Risk factors they had were previous histories of abdominal or pelvic surgery (37.0%), artificial abortion (30.8%), pelvic inflammatory disease (12%), and tubal sterilization (9.6%). Most frequent clinical symptoms were amenorrhea (88.7%), lower abdominal pain (81.2%), and vaginal spotting (60.0%). Percentage of patients with hemoglobin level over 10.0 gm/dL was 79% and below 8.0 gm/dL 3.9%. The clinical symptoms of ectopic pregnancy most commonly occurred after 6~8 weeks from last menstrual period (47%). Ectopic gestation was implanted on the fallopian tube in 89%, cornus in 7.2%, ovary in 1.1% and the cervix in 2.7%. Laparosopic surgeries were performed in 755 cases (71.6%) and laparotomies in 273 cases (25.9%) and dilatation and curettages in 26 cases (2.5%). Salpingectomy was performed most frequently (82.4%). Methotrexate (MTX) treatment was successful in 13 cases (1.21%). Conclusion: The early diagnosis of ectopic pregnancy is most useful when serum β-hCG and vaginal sonography are used together. Laparoscopy would be a preferred method because of its short hospitalization period and low complication rate compared with laparotomy in ectopic pregnancy treatment.

원발성 난소임신

문진성 ( Jin Sung Moon ),이연은 ( Yeun Eun Lee ),최영실 ( Young Sil Choi ),양성천 ( Seong Cheon Yang ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.12

멍게의 물렁증 발생에 미치는 용존산소의 영향

신윤경 ( Yun Kyung Shin ),박정준 ( Jung Jun Park ),전제천 ( Je Cheon Jun ),명정인 ( Jeong In Myeong ),양성진 ( Sung Jin Yang ) 한국환경생물학회 2013 환경생물 : 환경생물학회지 Vol.31 No.3

본 연구는 멍게 대량폐사의 주요 현상으로 나타나고 있는 물렁증 발생의 원인을 찾기 위하여 저산소의 영향에 의한 물렁증 발생, 생존률, 대사율 및 병리조직학적 변화를 분석하였다. 용존산소의 감소에 따른 멍게의 생존률은 용존산소 농도 2 mg L-1에서 노출 4일째 모두 폐사하였으며, 3 mg L-1에서는 노출 5일째 50%를 나타내어 5days-LC50은 3.55 mg L-1 (1.86~4.96 mg L-1)로 나타났다. 그러나 저산소에 노출된 기간 동안 물렁증 발생은 관찰되지 않았다. 산소소비율은 대조구와 비교하여 용존산소 농도 5 mg L-1 이하에서 유의하게 감소하여 저산소에 노출되면 일정기간 호흡률을 조절하는 것으로 추정된다. 저산소에 의한 멍게의 새낭, 소화선 및 피낭의 병리조직학적인 변화는 각 기관을 구성하고 있는 상피세포층의 괴사, 혈구세포의 침윤, 세포핵 응축 및 변형등이 관찰되었다. 형태적인 변화는 피낭이 쪼글어들어부피가 작아지고 내부 기관은 탈색되고 아가미와 간췌장의 괴사가 관찰되었다. This study analyzed the occurrence of tunic softness, survival rate, metabolic rate and histopathologic changes arising from the effect of hypoxic environment in order to find the causes of occurrences of tunic softness, which manifests as the key phenomenon of mass mortality of Halocynthia roretzi. Regarding the survival of H. roretzi with reduction in dissolved oxygen, all the entities died on the 4th day of exposure to the dissolved oxygen concentration of 2 mg L-1 while 50% mortality was observed on the 5th day of exposure to the dissolved oxygen concentration of 3 mg L-1. Therefore the 5 days-LC50 was found to be 3.55 mg L-1 (1.86~4.96 mg L-1). However, occurrence of tunic softness was not observed during the period of exposure to low oxygen concentration. The oxygen consumption rate significantly decreases at the dissolved oxygen concentration of less than 5 mg L-1 in comparison to the control group. Therefore, it is presumed that H. roretzi controls the respiration rate for prescribed period of time when exposed to hypoxic environment. Regarding the histopathologic changes in the gill, digestive gland and cyst of H. roretzi due to hypoxic environment, necrosis of epithelial layer, in filtration of blood cells, and condensation of nucleus that compose each of the organs were observed. Regarding morphological changes, the decrease in volume with shrinking of the tunic, discoloration of the internal organs and necrosis of gill and hepatopancreas were observed.