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비스포스포네이트 제제 관련 관절통 및 근육통에 대한 지역 약국 약사 및 환자 능동적 모니터링
송정우,박소희,윤동원,이모세,이정민,김나영,김영욱,이주연,신주영,Song, Jung-woo,Park, So-Hee,Yoon, Dongwon,Lee, Mo-Se,Lee, Jung-Min,Kim, Na-Young,Kim, Young-Wook,Lee, Ju-Yeun,Shin, Ju-Young 한국임상약학회 2021 한국임상약학회지 Vol.31 No.3
Objective: We investigated arthralgia and myalgia associated with the use of oral bisphosphonate (BP) by conducting a survey of patient. Methods: The pharmacists conducted a survey between 1 Oct 2019 and 30 Sep 2020 among patients who were dispensed BP in community pharmacies to assess their demographic and medical characteristics, and their experiences with, and process for pain. Logistic regression analyses were performed to find the risk factors associated with the pain, and the odds ratios (OR) and 95% confidence intervals (CI) were determined. Results: A total of 160 patients who used BP participated in the survey (74 [46.3%] used risedronate; 61 [38.1%] used alendronate; 23 [14.4%] used ibandronate), and 20 (12.5%) of them experienced pain. Significant statistical differences of the characteristics between patients who experienced pain or not were observed regarding menopause, and parity. Compared with women who had one or two parity, women who had more than three parity were associated with the decreased risk of pain (OR, 0.24; 95% CI, 0.04-0.98). Moreover, steady exercise was associated with the decreased risk of pain compared to less exercise (OR, 0.37; 95% CI, 0.14-0.98). Conclusion: Our findings suggest that the risk of pain in BP-treated patients might be different regarding the different ingredients of BP, and dosing frequency. This survey highlights a need for a further safety research to understand the factors influencing the pain associated with the BP treatment.
송정우,이긍호,Song, Jung-Woo,Lee, Keung-Ho 대한소아치과학회 2002 大韓小兒齒科學會誌 Vol.29 No.3
뇌성마비인의 구강위생상태에 관한 조사를 위하여 $3{\sim}48$세의 뇌성마비인 총264명(남153명, 여111명)과 비교군으로 비슷한 연령대의 비뇌성마비인 220명(남125명, 여95명)을 대상으로 구강검사를 시행하고, 우식경험유치율(dft rate), 우식경험유치지수(dft index), 우식경험영구치율(DMFT rate), 우식경험영구치지수(DMFT index), 치태지수(plaque index)를 산출하여 비뇌성마비인과 비교하였으며, 지적, 행동, 언어장애의 정도, 유형 및 이환 부위, 거주형태, 보호자의 직업에 따라 분류, 비교하여 다음과 같은 결과를 얻었다. 1. DMFT rate, DMFT index, dft index에서 뇌성마비군과 비뇌성마비군의 유의한 차이가 없었고, dft rate는 유의한 차이로 뇌성마비군이 높게 나타났다. 2. 뇌성마비군의 성별, 유형 및 이환 부위별 비교에서 우식경험도의 유의한 차이를 보이지 않았다. 3. DMFT rate와 DMFT index는 각각의 장애의 정도가 심할수록 유의성 있는 차이로 감소하였으며, 거주형태에서는 수용군이 비수용군에 비해 낮았고, 보호자 직업에서는 자영업이 낮게 나타났다. 4. 치태지수에서 뇌성마비군이 비뇌성마비군보다 유의성 있게 높았고, 거주형태에서는 비수용군이, 보호자 직업에서는 스스로 벌어서 생활하는 경우가 유의성 있는 차이를 보이며 높게 나타났다. 5. 치태지수에서 뇌성마비군의 성별, 유형 및 이환 부위, 각각의 장애의 정도에 대해서는 유의한 차이를 보이고 있지 않았다. The purpose of this study was to make a comprehensive study and to provide information about the dental caries and plaque index of cerebral person, and to aid improvement of their oral health. The author examined intraorally 1180 deciduous teeth, 5626 permanent teeth of 264 (male:153 female:111) cerebral palsy person and 1526 deciduous teeth, 4140 permanent teeth of 220 (male:125 female:95) non cerebral palsy person as the control group. The results were as follows : 1. Cerebral palsy persons Had higher dft rate than non-cerebral palsy persons. 2. Dental caries incidence between males and females in cerebral palsy persons showed no difference, and dental caries incidence of types in cerebral palsy person showed no difference, either. 3. Mental, motor, speech handicap degrees were negatively related to DMFT rate and DMFT index, and institutionalized cerebral palsy persons and cerebral palsy persons of which parent's occupation is private business were found low DMFT rate and DMFT index. 4. Cerebral palsy persons were found to have higher plaque index than non-cerebral palsy persons, and non institutionalized cerebral palsy persons and self-supported cerebral palsy persons were found high plaque index. 5. Plaque index of male and female in cerebral palsy person showed no difference, and Plaque index of types in cerebral palsy person showed no difference, either Plaque index of handicap degrees(mental, motor, speech) showed no difference.
조재영(Jaeyoung Cho),송정우(Jeongwoo Song),이태경(Taekyung Lee),김용태(Yongtae Kim),송한호(Han Ho Song) 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.12
Waste incinerator is difficult to control since the composition of solid refused fuel (SRF) can change randomly under certain specification. In this study, a model-based controller was designed for waste incinerator and steam generator by using linear-quadratic regulator (LQR). Input variables were chosen as air and fuel supply rates, and output variables were steam flow rate and oxygen concentration of exhaust gas, thus requiring a multi-input multi-output (MIMO) control scheme. Control gain matrix was evaluated repeatedly at each time step based on nonlinear control model, which could predict the output variables covering the range of operations for the incinerator plant installed in Ul-San-Si. Then, the controller was applied to the developed plant model, which was validated with the experimental data of the designated plant. As a result, the disturbance on the system was effectively rejected, and steam production rate could be controlled to achieve the desired values.