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Understanding of chemolithoautotrophic acetogenic bacterial genomes
송요셉,신종오,조병관 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0
Chemolithoautotrophic acetogenic bacteria are obligate anaerobic and gram-positive bacteria, which are in general capable of converting C1 compounds to multi-carbon compounds such as complex carbohydrates or long-chain fatty acids. The bacteria utilize CO, CO2, and H2 as precursors and produces chemicals including butyrate, caproate, and acetate via microbial metabolism, known as syngas fermentation. Compare to traditional thermochemical processes like Fischer-Tropsch synthesis, syngas fermentation of acetogenic bacteria produces industrial commodities with higher catalyst specificity and lower energy costs. However, the lack of genetic information on the bacteria hinders strain engineering and limits the production of those value-added chemicals for the industrial applications. In this study, we have obtained and analyzed the draft genome sequences and metabolic pathways of the acetogenic bacteria in order to elucidate their physiological and metabolic properties.