Case Reports of Adipose-derived Stem Cell Therapy for Nasal Skin Necrosis after Filler Injection

성하민,서인석,이훈범,탁경석,Kyung Min Moon,Min su Jung 대한성형외과학회 2012 Archives of Plastic Surgery Vol.39 No.1

With the gradual increase of cases using fillers, cases of patients treated by non-medical professionals or inexperienced physicians resulting in complications are also increasing. We herein report 2 patients who experienced acute complications after receiving filler injections and were successfully treated with adipose-derived stem cell (ADSCs) therapy. Case 1 was a 23-year-old female patient who received a filler (Restylane) injection in her forehead,glabella, and nose by a non-medical professional. The day after her injection, inflammation was observed with a 3×3 cm skin necrosis. Case 2 was a 30-year-old woman who received a filler injection of hyaluronic acid gel (Juvederm) on her nasal dorsum and tip at a private clinic. She developed erythema and swelling in the filler-injected area A solution containing ADSCs harvested from each patient’s abdominal subcutaneous tissue was injected into the lesion at the subcutaneous and dermis levels. The wounds healed without additional treatment. With continuous follow-up, both patients experienced only fine linear scars 6months postoperatively. By using adipose-derived stem cells, we successfully treated the acute complications of skin necrosis after the filler injection, resulting in much less scarring,and more satisfactory results were achieved not only in wound healing, but also in esthetics.

Ta₂O₅/SiO₂를 이용한 고출력 광섬유 레이저의 펌프 LD 보호기용 반사형 필터 설계 및 제작

성하민,김재헌,이석,전영민,Sung, Hamin,Kim, Jae Hun,Lee, Seok,Jhon, Young Min 한국광학회 2012 한국광학회지 Vol.23 No.3

본 논문에서는 고출력 광섬유 레이저에서 역입사되는 레이저 광으로부터 펌프 LD를 보호하기 위한 반사형 2색 필터를 설계하고 제작하였다. 펌프 LD 발진 파장인 905 nm~925 nm 대역에서 투과율은 0.1%이하, 광섬유 레이저 출력 반사광이나 브릴루앙 산란광 파장대역인 1020 nm~1100 nm 대역에서 투과율은 99.9% 이상이 되도록 필터를 설계하였다. 기판(Substrate)은 $SiO_2$로 사용하고 접착력이 우수한 Oxide 계열 물질인 $SiO_2/Ta_2O_5$를 박막 재료로 사용하였다. 최적화된 설계를 한 후 필터를 제작하였고, 그 특성을 비교하였다. 제작된 필터의 투과율이 905 nm ~ 925 nm 대역에선 0.1%이하, 1020 nm~1100 nm 대역에선 95.5%이상으로 측정되어 공정오차를 고려한 설계범위 안에 들어옴을 확인하였다. 제작된 필터는 레이저 출력 1W이상의 입력광에 대해서도 정상 동작함을 확인하였다. We designed and fabricated dichroic filters for high-power fiber lasers to protect the pumping laser diode from counterpropagating laser beams. The transmittance at laser diode wavelengths of 905 nm~925 nm was designed to be less than 0.1% and the transmittance at the fiber laser or Brillouin scattering wavelengths of 1020 nm ~ 1100 nm was designed to be more than 99.9%. Since oxide materials have good adhesion to the $SiO_2$ substrate, $SiO_2/Ta_2O_5$ were used as coating materials. The filter was fabricated according to our optimized design and its characteristics were compared with the theoretical design. As a result, the transmittance at laser diode wavelengths of 905 nm~925 nm was measured to be less than 0.1%, and the transmittance at the fiber laser or Brillouin scattering wavelengths of 1020 nm~1100 nm was measured to be more than 95.5%, which coincided well with the theoretical design considering processing errors. The filter was found to operate well over 1W of input laser power.

성형외과 영역에서 이물질 주사에 대한 고해상초음파 검사의 유용성

고응열,성하민,조건,박영규,탁경석,서인석,양익,Ko, Eung-Yeol,Sung, Ha-Min,Cho, Geon,Park, Young-Kyu,Tak, Kyoung-Seok,Suh, In-Suck,Yang, Ik 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.4

Purpose: The purpose of this study is to demonstrate the usefulness of the high resolutional ultrasonographic features in patients with foreign body. Methods: From September 2007 to August 2009, we retrospectively reviewed high resolutional ultrasonogram using 5~12 MHz linear transducer of 13 patients presenting with inflammation after foreign body injection. They were referred for complications after foreign body injection. Injected foreign bodies were 4 silicone, 4 paraffin, 2 artecoll, and 3 unknown. We treated them with foreign body removal (7), foreign body removal and corrective plastic surgery (4), and conservative treatment with antibiotics and steroid injection (2). Results: High resolutional ultrasonography well demonstrated the existence of foreign body and it's overall size, location within the tissue layer, and vascularity. Comparison between preoperative and postoperative ultrasonographic findings was useful not only to evaluate the prognosis but also to plan the treatment. These ultrasonographic findings aided in precise assessment of the contour and location of the foreign body and led to an accurate surgery. We were able to acquire various information in order to set a detailed plan for the operation which in turn, led to a precise, successful surgery. After the treatment, complication did not occur in 12 patients, except 1 patient. But this patient was also treated after reoperation. Postoperative high resolutional ultrasonography shows almost foreign body removed and inflammation disappeared. Conclusion: Considering the usefulness of highresolution ultrasonography in foreign body injection, highresolution ultrasonography would be necessary for both the patient and the doctor. Preoperative and postoperative high resolutional ultrasonography is highly accurate, safe, inexpensive and easy. It can be a useful modality in foreign body after plastic surgery.

Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin

김현우,정지혁,성하민,김석화 대한두개안면성형외과학회 2017 Archives of Craniofacial Surgery Vol.18 No.4

A 17-month-old boy was evaluated for a midline mass on his chin. The mass was anchored to the mentalis muscle with a stalk-like structure. The pathological diagnosis of the mass was rhabdomyomatous mesenchymal hamartoma. This is the first report of rhabdomyomatous mesenchymal hamartoma presenting as a midline chin mass in Korean pediatric patients.

원발성 이하선 비호지킨 림프종 : 증례보고

조건,서인석,탁경석,박영규,고응열,성하민,신미경 대한두개안면성형외과학회 2010 Archives of Craniofacial Surgery Vol.11 No.2

Purpose: Primary malignant lymphomas of the salivary glands are uncommon, representing only 1.7%to 3.1% of all salivary neoplasms and 0.6% to 5% of all tumors and tumor-like lesions of the parotid gland. Lymphomas of the parotid glands are usually manifestations of a systemic disease process but primary lymphomas of the parotid glands are rare. Most of these lesions are classified as extranodal non-Hodgkin's lymphoma. We report the clinicopathological features of primary malignant lymphoma of the parotid gland based on an analysis of our cases. Methods: The subject was a 48-year-old male patient with a malignant lymphoma originating in the parotid gland, which had been slowly increasing in size over previous 6 months. The diagnosis was established by MRI and a superficial lobectomy. After diagnosis, the patient was referred to an oncologist for staging and medical treatment. Results: The stage was IIIA. The patient was treated with chemotherapy following surgery with rituximab and CHOP (Cyclophosphamide, Adriamycin, Vincristine, Prednisolone). The tumor was controlled successfully by chemotherapy. The patient was followed up for 1 year with no relapse. Conclusion: A case of primary non-Hodgkin's lymphoma of the parotid gland was treated with a superficial parotidectomy and chemotherapy. The disease was well controlled after a 1 year follow-up. (J Korean Cleft Palate Craniofac Assoc 11: 99, 2010)

성형외과 영역의 수술 시 마취하 감시관리의 응용에 대한 고찰

조건,서인석,최영룡,정미화,탁경석,박영규,김재현,고응열,성하민 대한성형외과학회 2011 Archives of Plastic Surgery Vol.38 No.1

Purpose: Many patients have fears of the surgery owing to the injection of lidocaine and the possible pain in the course of the operation. For resolving such problems the cases to do plastic surgery with monitored anesthetic care, in which something like sedatives is injected into vein without endotracheal intubation and under voluntary respiration are increasing, but the usage is now under the controversy. Methods: There are 25 patients who had surgery with local anesthesia and also 25 patients who had surgery with monitored anesthetic care which belong to ASA class 1 and 2 from January to April, 2009. Records about their anesthesia were collected and surveys sere given before and after the surgery and the surgery staff recorded OAA / S during the surgery. And surveys after the surgery were also given about the awakening during the surgery, pain, anxiety, and the degree of patient's satisfaction through visual analogue scale to know the difference between the two ways. Results: The results OAA / S results according to time lapse show that it was possible to lead a fast effective sedation and recovery with monitored anesthetic care, and monitored anesthetic care had higher result of surgeon's convenience and patient's satisfaction, but in regard with awakening, pain, and anxiety were lower than local anesthesia. Conclusion: The current paper shows about the plastic surgery, particularly the outpatient surgery, when monitored anesthetic care method is applied, could gain a fast sedation and recovery or an effective sedation of patients. The method also has some affirmative effects in regard with surgeon's convenience and the patients' satisfaction degree and the reduction of their awakening, pain, and anxiety so that if there is careful and adequate watch and measures about vital signs like electrocardiogram, the degree of oxygen saturation, and blood pressure it could clinically be very useful.

펨토초 광섬유레이저 기반 비열 초미세 녹색 가공기술

김남성(Nam Seong KIM),김기혁(Kihyuck KIM),정영대(Youngdae CHUNG),최창기(Changgi CHOI),이도경(Dohkyeong LEE),이승재(Seungjae LEE),성기석(Geesuk Sung),전영민(Youngmin JHON),성하민(Hamin SUNG),오경환(Kyunghwan OH),김종기(Jongki KIM),박지영 한국생산제조학회 2010 한국공작기계학회 추계학술대회논문집 Vol.2010 No.-

기존 레이저 미세가공기술 한계를 극복하여 LCD/AMOLED 등의 가공물 내부와 표면에 10㎛ ~ 500㎚ 까지의 초정밀청정가공을 하는 기술개발로서 관련된 고부가가치 생산시스템개발 및 시장요구형 50W/300fs/1035㎚/10㎒ 펨토초 광섬유레이저 기술개발을 소개한다. 기술개발은 2010년6월부터 2015년3월말까지 진행할 예정이며 현재 3개월여의 기술개발을 수행하고 있다. 1차년도 기술개발목표는 레이저광원으로서 20㎽/1035㎚/10㎒/300fs의 모드잠금광섬유레이저를 개발하는 것과 응용프로세스개발은 7㎛급의 내부 3차원 초미세 가공과 표면 초미세가공 등이다. (지식경제부 산업원천기술개발사업 프로젝트번호 10037371).