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성지수,Kim Hoon,Park Wan Beom,Kim Nam Joong,Oh Myoung-don,Park Sung Sup,박중신,최영민 대한의학회 2020 Journal of Korean medical science Vol.35 No.25
With highly active antiretroviral therapy, human immunodeficiency virus (HIV) infection is considered to be a manageable chronic disease. The improved prognosis increases the desire of individuals with HIV to have biological offspring. With the establishment of washing protocol, no HIV transmission has been reported among more than 11,000 assisted reproduction technology (ART) cycles. Although the Acquired Immunodeficiency Syndrome Prevention Act in Korea prevents the use of HIV-infected blood, organs, tissues and semen, we recently obtained the authentic approval from the Korea Centers for Disease Control and Prevention for the practice of ART in HIV-serodiscordant couples. We report a 32-year-old HIV-seronegative female with her husband who was HIV-1 seropositive. After semen washing was performed by means of a density gradient and the swim-up technique, HIV-1 ribonucleic acid was not detected in the semen. An aliquot of processed semen was cryopreserved before ART. None of 3 cycles of intrauterine insemination was successful. After the third frozen-thawed embryo transfer following two cycles of intracytoplasmic sperm injection, an intrauterine singleton pregnancy was identified. She gave birth to a normal healthy male baby at full term by Cesarean section. She and her baby were tested for HIV during pregnancy and after delivery and the results were negative. Semen washing may be a safe ART method for HIV-serodiscordant couples who desire to have a baby in Korea.
학령전기 말더듬 아동의 언어단위에 따른 비유창성률 및 구어속도 비교
성지수,전희숙 한국언어치료학회 2019 言語治療硏究 Vol.28 No.4
When comparing the characteristics of a child’s disfluency, the results can vary depending on the language unit. This study compared the characteristics of disfluency of Preschool-Age Children Who do and do not stutter. quantitatively by using different language units such as syllables, words and Eojeols. Methods: The study compared the difference in disfluency rate and the speech rate based on language units for a total of 36 preschool children, composed of 18 children who stutter and 18 children who do not stutter. Results: First, as the result of comparing disfluency rates between the stuttering preschool children group and the general preschool children group based on language units, the stuttering children’s overall disfluency of syllable unit was lower than that of word and that of Eojeol units in overall disfluency rate, normal disfluency rate and abnormal disfluency rate. On the other hand, in the general preschool children group, there was no difference in disfluency rate based on the language units in overall disfluency rate, normal disfluency rate and abnormal disfluency rate. Second, as a result of analysis on stuttering preschool children’s overall speech rate and articulation rate and general preschool children’s by phoneme and syllable units, there was no difference between them. Conclusions: The results of this study demonstrate that, in the comparison analysis of stuttering preschool children’s disfluency rate and general preschool children’s, the difference between the two groups becomes greater when the language unit is larger than smaller, and that the analysis of speech rate of mildly stuttering children is not significantly affected by the language units. 아동의 비유창성 특성을 비교하는 경우 언어단위에 따라 결과가 다르게 나타날 수 있다. 본연구는 학령전기 말더듬 아동 및 일반 아동을 대상으로 음절, 단어 및 어절 등의 언어단위를나누어 비유창성 특성을 수치화하여 비교하였다. 방법 : 학령전기 말더듬 아동 18명, 일반 아동18명, 총 36명을 대상으로 언어단위에 따른 비유창성률과 구어속도에서 어떤 차이가 있는지를비교하였다. 결과 : 첫째, 학령전기 말더듬 아동과 일반 아동의 집단별 언어단위 간 비유창성률을비교한 결과, 전체 비유창성률, 정상적 비유창성률 및 병리적 비유창성률 모두 말더듬 아동은음절 단위의 전체 비유창성률이 단어 및 어절 단위보다 낮게 나타났다. 반면 일반 아동의 경우전체 비유창성률, 정상적 비유창성률 및 병리적 비유창성률 모두에서 언어단위에 따라비유창성률에 차이가 없었다. 둘째, 학령전기 말더듬 아동과 일반 아동 집단 간 전체구어속도 및조음속도를 음소, 음절 단위로 분석한 결과, 모두 차이가 없었다. 결론 : 이상의 연구 결과를살펴보면 학령전기 말더듬 아동 및 일반 아동의 비유창성률을 비교 분석하기 위한 언어단위가작은 단위보다 큰 단위일 때 그 차이가 두드러지게 나타나는 것을 알 수 있었다. 그리고 경증의말더듬 아동의 구어속도를 분석할 때에는 언어단위에 크게 영향을 받지 않는다는 것을 알 수있었다.
Prenatal screening for neural tube defects: from maternal serum alpha-fetoprotein to ultrasonography
김광준,성지수,오진아 대한산부인과학회 2023 Obstetrics & Gynecology Science Vol.66 No.1
The two main screening tests during pregnancy are those for chromosomal abnormalities and neural tube defects(NTDs). In particular, for NTDs, measurement of maternal serum alpha-fetoprotein (MSAFP) levels early in the secondtrimester (15-18 weeks of gestation) has been considered the gold standard screening test for the past 4 decades. However, with remarkable technological advancements and the widespread use of ultrasound during those periods,mid-trimester ultrasonography has gradually replaced the role of measuring MSAFP levels as a screening method forNTDs. This change was initiated more about 10 years ago in some countries, which have issued national guidelinesto use mid-trimester ultrasonography instead of measuring MSAFP levels as a prenatal screening method for NTDs. However, no significant changes have occurred in Korea, where second-trimester ultrasonography is routinelyperformed with high-quality equipment. We aimed to provide information regarding the importance of changing thescreening method for NTDs from MSAFP measurement to ultrasonography, and to detail methods of implementingmid-trimester ultrasonography for screening purposes. We also share our experience of operating a prenataldiagnostic program for NTDs without using MSAFP for more than 15 years.
대구지역 의료기관의 CT, MRI 보유 현황과 정도관리에 관한 담당 방사선사들의 인식 조사
이창석,조인성,이상욱,정석종,성아라,이현정,형미림,성지수,박창희,Lee, Chang-Suk,Jo, In-Seong,Lee, Sang-Uk,Jeong, Seok-Jong,Sung, A-Ra,Lee, Hyun-Jung,Hyung, Mi-Rim,Seong, Ji-Su,Park, Chang-Hee 대한디지털의료영상학회 2011 대한디지털의료영상학회논문지 Vol.13 No.3
This study concerns the present possession of CT and MRI machines in Daegu and the technologists' awareness of Quality Control. the study was conducted by visiting forty medical institutions as well as a survey. The survey was carried out by technologists responsible for CT and MRI. CT and MRI machines have only been used in medical institutions in Daegu for a short period. The study revealed that most of them have been acquired by those institutions recently. Most of the technologists who participated in the study are aware of the (prescribed) Quality Control measures and conduct regular inspections in accordance with the quality control chart, however some of them do not.