Regional Difference of Causative Pollen in Children with Allergic Rhinitis

성명순,김성원,김정희,임대현 대한의학회 2017 Journal of Korean medical science Vol.32 No.6

The aim of this study was to investigate role of common pollen in Korean school-aged children with allergic rhinitis (AR) in 5 provinces (Incheon Metropolitan City-Gyeonggi Province, Chungcheongbuk-do, Gwangju Metropolitan City, Busan Metropolitan City, and Jeju Special Self-Governing Province), using a questionnaire and skin prick test, and to assess the differences among the residential regions. Among the enrolled 14,678 total children, 1,641 (22.0%) had AR. The sensitization rate to pollen (38.7%) was the second highest among examined allergens and significant differences were in the sensitization rates to trees, weeds, and grasses among the 5 provinces (P < 0.05). The sensitization to trees (25.2%) was the highest common among the pollen types and significant differences also were observed in the sensitization rates to alder, birch, Japanese cedar, oak, and elm among the 5 provinces. The sensitization rate to weeds (19.9%) was the second highest and significant differences were observed in the sensitization rate to Japanese hop, mugwort, and ragweed among the 5 provinces. The sensitization rate to house dust mite was 86.8%, the highest among examined allergens and that to Dermatophagoides farinae exhibited regional differences (P = 0.003) but not to D. farinae (P = 0.584). The sensitization rate to mold (13.5%) was the highest in Jeju and lowest in Busan, and a statistically significant difference was detected among the 5 provinces. These results support that examined pollen allergens are strongly associated with residential region due to regional causative pollen differences among children with AR within Korea to investigate the main pollen allergens.

항공사-여행사의 의사교환이 파트너쉽에 미치는 영향

성명순 경북과학대학 2001 金龜論叢 Vol.8 No.1

우리나라의 여행업은 관광산업 발전의 핵심적 기능을 수행하고 있다. 그러나 영세한 규모의 여행사들이 고객의 다양한 관광욕구를 체계적으로 충족시킬 마케팅전략을 수립하고 실행하기엔 역부족인 상태이다. 이러한 현실 하에서 국내여행사는 오랜 경험과 노하우 및 거대한 자원을 보유하고 있는 외국여행사들과 경쟁을 하기 위해서는 보다 빠르게 관광객의 요구 및 욕구에 대처해 나아갈 수 있는 효율적인 마케팅전략의 하나로서 파트너쉽의 관계가 요구된다. 이에 본 연구는 산업현장에서의 정확한 파트너쉽의 개념을 전략적 관점에서 새롭게 정의 하고자 한다. 또한 관광유통경로 상에서 항공사와 여행사간의 관계성인 의사교환과 파트너쉽에 대한 결속의 구성요인인 신뢰가 파트너쉽과 어떤 영향관계가 있는지 선행연구를 바탕으로 실증적으로 분석한다. 이를 통하여 항공서비스산업에서 파트너쉽의 도입과 정착이 곧 경쟁력회복의 원천임을 제시하고자 한다.

lease 有用性 分析에 관한 實證的 硏究 : S제조기업의 事例分析을 中心으로

成明順 효성여자대학교 법경대학학도호국단 1981 法經論叢 Vol.1 No.-

심한 변비와 복부팽만으로 발견된 소아 크론병 1예

성명순,강석정,최광해 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Crohn's disease is a chronic inflammatory bowel disease that mainly affects children and young adults, Its cause remains unknown. The incidence of pediatric Crohn's disease is increasing, so it is important for clinicians to be aware of the presentation of this disease in the pediatric population The majority of patients complain of abdominal pain (72%), with only 25% Presenting with the 'classical triad' of abdominal pain, weight loss, and diarrhea. Many children with Crohn's disease present in a 'non-classical' manner, with vague complaints such as lethargy or anorexia, which may be associated with only mild abdominal discomfort Other symptoms include fever, nausea, vomiting, growth retardation, malnutrition, delayed Puberty, Psychiatric symptoms, arthropathy, and erythema nodosum. Severe constipation and abdominal distension are uncommon symptoms at diagnosis. We report a case of pediatric Crohn's disease, which was diagnosed after the patient presented with severe constipation and abdominal distension.

실외 대기오염물질이 소아청소년 알레르기비염에 미치는 영향

성명순,김민지,김현희,나영호,박양,박용민,신윤호,염혜영,이경석,이용주,전윤홍,지혜미,최봉석,최선희,김효빈,대한 소아알레르기 호흡기학회 비염 연구회 대한 소아알레르기 호흡기학회 2022 Allergy Asthma & Respiratory Disease Vol.10 No.3

The global worsening of air pollution has decreased the quality of life. Air pollutants can induce oxidative stress, epigenetic changes, and alterations to microRNA expression in the airway and skin, leading to immune dysregulation. Previous epidemiological studies suggest a strong association between outdoor environmental pollution and childhood allergic disease, especially allergic rhinitis (AR). Moreover, traffic-related air pollution has increased the severity and incidence of AR, and heavy traffic has been associated with an increased prevalence of AR. Thus, this review aimed to define outdoor environmental pollution and clarify the mechanisms by which air pollutants aggravate AR. In addition, we performed a systematic review and meta-analysis to summarize the findings of several domestic and international epidemiological and clinical studies about the effects of air pollution on AR in children.

2009년 신종 인플루엔자로 영남대학교 의료원에 입원한 환아의 실태 조사

성명순,최광해 영남대학교 의과대학 2010 Yeungnam University Journal of Medicine Vol.27 No.1

The clinical picture in severe cases of pandemic (H1N1) 2009 influenza is markedly different from the disease pattern seen during the epidemics of seasonal influenza as many of those affected were previously healthy young people. Current predictions estimate that during a pandemic wave, 12∼30% of the population will develop clinical influenza (compared with 5 ∼15% for seasonal influenza) with 4% of those patients requiring hospital admissions and one in five requiring critical care. Until July 6, 94,512 people have been infected in 122 countries, of whom 429 have died with an overall case-fatality rate of <0.5%. Most of the confirmed cases of S-OIV (Swine- Origin Influenza A Virus) infection have been characterized by a self-limited, uncomplicated febrile respiratory illness and 38% of the cases have also included vomiting or diarrhea. Efforts to control these outbreaks are based on our understanding of novel S-OIV (Swine-Origin Influenza A Virus) and the previous influenza pandemics. So, this review covers the experience with S-OIV (Swine-Origin Influenza A Virus) for the admission and background data and the clinical presentation, diagnosis and treatment of H1N1 in pediatric patient with S-OIV (Swine-Origin Influenza A Virus) at YUMC, 2009.

학동기 및 사춘기 아토피피부염 환아에서 메타콜린 기도과민성에 영향을 미치는 요인에 대한 분석

성명순 ( Myong Soon Sung ),최진욱 ( Jin Wook Choi ),황영진 ( Young Jin Hwang ),김성원 ( Sung Won Kim ) 대한소아알레르기호흡기학회 1992 소아알레르기 및 호흡기학회지 Vol.2 No.3

Purpose: Many studies have shown the importance for bronchial hyperresponsiveness (BHR) in children with bronchial asthma and allergic rhinitis. However, studies have not been done in BHR in school age and adolescence with atopic dermatitis (AD). Methods: The patients with history of bronchial asthma were excluded and methacholine challenge test (MCT) was performed in 103 children with atopic dermatitis. The positive of MCT result is defined as provocative concentration of methacholine causing a 20% fall in forced expiratory volume in 1 second (PC20)≤8 mg/mL. According of the level of PC20, the patients were divided into two groups. Results: The group 1 (BHR+) was observed in 43 of all patients (41.7%). Of two groups, significant differences were observed in age, body mass index. No significant differences were observed in the number of male, SCORing Atopic Dermatitis (SCORAD) index, admission history, smoking exposure history, other allergic disease, parental allergic disease. The group 1 (BHR+) have higher levels of total eosinophil count compared with the group 2 (BHR.) (629.8±360.5/μL vs. 470.2±253.9/μL, P=0.01). But no significant association was found between severity of BHR and SCORAD score, total immunoglobulin E, total eosin ophil count and eosinophil cationic protein (r=0.008, P=0.961; r=.0.217, P=0.162; r=0.225, P=0.147; r=.0.032, P=0.841). The list of allergen is that the house dust mite, tree, weed, food, animal hair, and fungus. The house dust mite has correlation with bronchial hypersensitivity statistically and the any of allergen groups, either. Conclusion: No significant relationship was observed between degree of BHR and allergy laboratory finding, severity of AD. (Allergy Asthma Respir Dis 2014;2:179-186)

학동기 및 사춘기 아토피피부염 환아에서 메타콜린 기도과민성에 영향을 미치는 요인에 대한 분석

성명순 ( Myong Soon Sung ),최진욱 ( Jin Wook Choi ),황영진 ( Young Jin Hwang ),김성원 ( Sung Won Kim ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.3

Purpose: Many studies have shown the importance for bronchial hyperresponsiveness (BHR) in children with bronchial asthma and allergic rhinitis. However, studies have not been done in BHR in school age and adolescence with atopic dermatitis (AD). Methods: The patients with history of bronchial asthma were excluded and methacholine challenge test (MCT) was performed in 103 children with atopic dermatitis. The positive of MCT result is defined as provocative concentration of methacholine causing a 20% fall in forced expiratory volume in 1 second (PC20)≤8 mg/mL. According of the level of PC20, the patients were divided into two groups. Results: The group 1 (BHR+) was observed in 43 of all patients (41.7%). Of two groups, significant differences were observed in age, body mass index. No significant differences were observed in the number of male, SCORing Atopic Dermatitis (SCORAD) index, admission history, smoking exposure history, other allergic disease, parental allergic disease. The group 1 (BHR+) have higher levels of total eosinophil count compared with the group 2 (BHR-) (629.8±360.5/μL vs. 470.2±253.9/μL, P=0.01). But no significant association was found between severity of BHR and SCORAD score, total immunoglobulin E, total eosin ophil count and eosinophil cationic protein (r=0.008, P=0.961; r=-0.217, P=0.162; r=0.225, P=0.147; r=-0.032, P=0.841). The list of allergen is that the house dust mite, tree, weed, food, animal hair, and fungus. The house dust mite has correlation with bronchial hypersensitivity statistically and the any of allergen groups, either. Conclusion: No significant relationship was observed between degree of BHR and allergy laboratory finding, severity of AD.

15년 동안 부산 지역에서 채집된 공중화분 분포 및 알레르기 감작률과의 상관관계

성명순 ( Myong Soon Sung ),박영진 ( Yong Jin Park ),박근화 ( Geun Hwa Park ),오재원 ( Jae Won Oh ),김성원 ( Sung Won Kim ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1

Purpose: pollen is the most common causative agents of allergic disease. Since 2000, there isn``t no more report about pollen in Busan. This study is that pollen in one area of Busan was collected to investigate species, particle counts, seasonal distribution, and of its correlation with reactivity to skin prick test in children during 1998.2012. Methods: Rotorod sampler was installed on the rooftop of St. Mary Hospital in Busan. A 24-hour sampling of allergens over a fifteen-year period was conducted 6 days/wk from January 1, 1998 to December 31, 2012. After staining they were identified, counted and recorded with the weather in Busan. Results: Major pollens collected were Pine, Alder, Oak, Juniperus, Humulus. The pollen season is relatively short and the pollen dispersed mainly during the period from March to May in case of tree pollen, from April to September in case of grass pollen and from August to October in case of weed pollen. Total annual pollen count ranged from 36,412 grains/m3 (2002) to 1,342 grains/m3 (2006). The peak pollen season was seen for spring and autumn, especially in May and September during 1998.2012. In skin prick tests, birch was the highest sensitization rate (15.1%), followed by alder (14.7%), hazel (14.1%) in the tree for 15 years. And in weed, mugwort and ragweed were the highest sensitization rate (10.6%, 10.3%), followed by humulus (5.5%) for 15 years, but since 2008, was increased. Conclusion: Analysis of pollens sampled in the atmosphere of Busan, Korea, for a 15-year period identified 24 species of pollens with seasonal variation of some clinically important pollen load. Analysis of data, it showed that alder and birch are main allergen in spring for 15 years, and in 1998.2008, ragweed and artemisia was main allergen in fall, since 2009, followed by humulus. (Allergy Asthma Respir Dis 2014;2:38-47)

충수염으로 속발된 요관폐색증 1례

강석정,성명순,최광해 영남대학교 의과대학 2009 Yeungnam University Journal of Medicine Vol.26 No.1

Appendicitis is a common cause of acute abdomen in pediatrics. Periappendiceal abscesses are frequently found in the pediatric population. Acute appendicitis in children can, at times, be a difficult clinical diagnosis because of its highly variable history? and physical manifestations and its unpredictable course. Despite the uncertainty of the diagnosis, appendicitis demands prompt treatment because of the risk of perforation, which occurs in approximately one third of cases. Urological manifestations of appendicitis and appendiceal abscess can vary. Acute appendicitis presenting with ureteral stenosis and hydronephrosis is very rare. Here, we report a case of acute appendicitis with perforation and left hydronephrosis in a 3-year-o1d female. This case presents a 3-year-old girl with dysuria having hydronephrosis that originated from a perforated appendix.