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서민희,유형곤-,Min Hee Suh,Hyeong Gon Yu- 대한안과학회 2009 대한안과학회지 Vol.50 No.1
Purpose: To investigate the clinical features and prognosis of primary intraocular lymphoma (PIOL). Methods: A retrospective review of medical records was performed in 9 patients who were diagnosed and treated as PIOL in the Department of Ophthalmology, Seoul National University Hospital. Results: Among patients who were enrolled in the study, 14 eyes were examined. Thirteen eyes (92.9%) showed yellowish subretinal or choroidal infiltrates which is a characteristic finding of PIOL in fundus examination and fluorescein angiography. Three patients presented with ocular symptoms initially, and 5 patients later presented with central nerve system (CNS) involvement. Only 1 patient showed PIOL without CNS involvement. Among 6 patients (9 eyes) that received systemic chemotherapy or ocular irradiation, 5 patients (7 eyes, 77.8%) responded. Among those patients, 3 patients (4 eyes) showed relapse of PIOL. Five patients died during the mean follow-up period of 43.3 months, and the median survival time was 47 months. Conclusions: The most common characteristic fundus finding of PIOL is subretinal or choroidal infiltration. Ocular irradiation combined with systemic chemotherapy is the first method of treatment, although long-term prognosis is poor.
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대학생의 성별, 스트레스, 불안 및 우울 정도에 따른 심박변이도 차이: Neurovisceral integration model에 기반하여
서민희(Suh Min Hee) 한국기초간호학회 2021 Journal of korean biological nursing science Vol.23 No.1
Purpose: This descriptive study aimed to investigate heart rate variability (HRV) according to sex and to elucidate the influence of negative emotion such as levels of stress, anxiety and depression on HRV among Korean college students based on a neurovisceral integration model. Methods: A descriptive study design was used. Eighty-six healthy college students participated in the study. Resting HRV and standing HRV on orthostatic stimulation were measured for 5 minutes during 4-6 p.m. in the afternoon. Levels of stress, anxiety and depression were assessed using the Global assessment of recent stress, State-Trait Anxiety Inventory and Beck Depression Index, respectively. Results: Out of the 86 students, 47 (54.7%) were men and 39 (45.3%) were women. Root mean square of the differences between adjacent RR intervals (RMSSD) and normalized high frequency (nHF) on standing HRV were significantly lower in men than in women (p=.005, p=.019, respectively). Male gender (β=0.30, p=.013), higher level of stress (β=-0.36, p=.009) and lower level of depression (β=0.30, p=.044) exerted a significant influence on decreased nHF in the multiple regression analysis. Conclusion: We suggest that men are more vulnerable to having reduced vagal activity on HRV than women. Since male gender, higher level of stress and lower level of depression level influenced decreased vagal activity, strategies are needed to improve stress and depression rather than anxiety especially for men, which contribute to promoting HRV to prevent cardiac health diseases.
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폐경여성에서 녹내장 발생과 혈중 에스트라디올 농도와의 관계
전균호 ( Gyun Ho Jeon ),조현진 ( Hyun Jin Cho ),전성욱 ( Sung Wook Chun ),지용일 ( Yong Il Ji ),정철회 ( Chul Hoi Jeong ),서민희 ( Min Hee Suh ),이주은 ( Joo Eun Lee ) 대한폐경학회 2013 대한폐경학회지 Vol.19 No.2
연구목적: 폐경여성에서 녹내장 발생과 혈중 에스트라디올 (estradiol, E2)농도와의 관련성을 알아보고자 하였다. 연구재료 및 방법: 산부인과 외래를 방문한 30명의 폐경여성을 대상으로 혈중 E2 농도, 폐경 관련 임상 지표, 안압, 빛 간섭 단층촬영 등의 녹내장 관련 임상 지표를 측정하였다. 안과적 선별 검사 결과에 따라 녹내장 의심 군으로 분류되면 정밀검사를 시행하여 녹내장 여부를 확진 하였다. 모든 환자들을 녹내장 의심 군과 녹내장 비의심군으로 분류한 후 두 군 사이의 혈중 E2 농도 및 지질 농도, 골밀도 등의 폐경 관련 임상 지표들을 비교 분석하였다. 결과: 전체 30명 중 녹내장 의심군으로 분류된 환자가 8명 (26.7%)였으며, 이중 1명이 치료가 필요한 녹내장, 2명이 초기 녹내장으로 진단되었다. 녹내장 의심 군과 비교하여 녹내장 비의심군에서 혈중 E2 농도가 더 높은 것으로 측정되었지만, 통계적인 유의성은 없었다 (19.40 ± 4.79 vs. 13.95 ± 4.55 pg/mL, P = 0.525). 혈중 E2 농도가 높은 군 (≥ 20 pg/mL)과 낮은 군 (< 20 pg/mL) 사이의 녹내장 의심자의 빈도 또한 유의한 차이가 없었고 (25.0 vs. 27.3%, P = 0.645), 녹내장 의심 군과 비의심군간의 다중 로지스틱 회귀분석을 시행한 결과에서도 녹내장 의심 군과의 유의한 연관성이 있는 지표는 역시 없었다. 결론: 폐경여성에서 빛 간섭 단층 촬영과 같은 정밀 선별검사를 시행한 결과 일반적으로 알려진 비슷한 연령대의 녹내장 유병 율보다 높은 빈도에서 녹내장 환자를 발견할 수 있었다. 혈중 E2 농도와 안압 및 녹내장 발생 위험간의 통계적 유의성은 확인할 수 없었다. Objectives: To investigate the occurrence of glaucoma and association with the serum estradiol (E2) level in postmenopausal women. Methods: We evaluated the serum E2 level, female reproductive factors and glaucoma related risk factors including intraocular pressure and optical coherence tomography (OCT) findings in 30 postmenopausal women who visited Obstetrics and Gynecology outpatient clinic. Patients who showed abnormal findings on the glaucoma screening test were classified to the glaucoma suspect group (group-G), and underwent a glaucoma confirmatory test. Serum E2 level, female reproductive and other menopausal health-related factors such as lipid profiles and bone mineral densities were analyzed in the group-G and non glaucomatous group (group-N). Results: Eight out of thirty participants (26.7%) were classified to the group-G. One of them was diagnosed as having glaucoma that required treatment, and the other two were found to have early glaucomatous changes. Compared to the group-G, the group-N had a higher level of serum E2 (19.40 ± 4.79 vs. 13.95 ± 4.55 pg/mL) The difference, however, was not statistically significant (P = 0.525). The proportion of glaucoma suspect patients in the groups with a higher serum E2 level (≥ 20 pg/mL) and a lower serum E2 level (< 20 pg/mL) was similar (25.0 and 27.3%, P = 0.645). Multiple logistic regression analysis showed that no female reproductive factors were associated with the risk of glaucoma. Conclusion: Comprehensive glaucoma screening using an OCT in postmenopausal women could detect more glaucoma patients than prevalence in the similar age group. Statistical significance was not found in the association between serum E2 level and the risk of glaucoma. (J Korean Soc Menopause 2013; 19:106-111)
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B형 간염예방에 대한 교육매체의 효과 : 중·고등학생을 대상으로
김매자,신계영,장애경,서민희 韓國學校保健學會 2005 韓國學校保健學會誌 Vol.18 No.1
Purpose: Our research team developed two types of hepatitis B prevention materials: video tape and leaflet. We showed them to two groups of subjects separately, and the effect of education was compared to find out a more effective educational material for preventing hepatitis B. Method: Students at a middle school and a high school, one class for each school year, participated in the five areas of this study. They were educated for hepatitis management using the video tape and the leaflet. Before and after the education, they were tested for knowledge on hepatitis and health belief to analyze the effect of education. Results: 1) The video tape was more effective than the leaflet in delivering hepatitis knowledge and enhancing sensitivity & severity in health belief. 2) Hepatitis knowledge was improved significantly after the education. 3) Sensitivity & severity in health belief was improved significantly after the education. 4) Benefit in health belief was improved significantly after the education 5) Barrier in health belief decreased significantly after the education. 6) There was a correlation between hepatitis knowledge, sensitivity & severity in health belief and benefit in health belief. Conclusion: We suggest that for preventing hepatitis B it would be helpful to educate students in middle school and high school face to face with educational materials.
KCI
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