일부 한국인 여성에서 뇌졸중 先行因子로서의 麻木

부송아(Song Ah Bu),선승호(Seung Ho Sun),고성규(Seong-Gyu Ko) 한의병리학회 2007 동의생리병리학회지 Vol.21 No.1

한국인의 뇌졸중 위험인자로서 커피 음용

고성규,부송아,Ko, Seong-Gyu,Bu, Song-Ah 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Objectives : To prevent stroke, it is very important to reduce risk factors which might cause stroke. However, previous studies that having investigated coffee consumption associated with stroke reported various results. In addition, there were only a few studies based on the Korean population. Therefore, we studied the association of coffee consumption and the possibility of getting stroke among Koreans. Methods : A case-control study was carried out on 207 cases(stroke patients) and 207 controls(non-stroke patients) in a hospital. Information on characteristics, health habits, dietary habits and coffee consumption were obtained through direct interview by using an organized questionnaire; WHR(Waist-Hip Ratio) was determined through physical examination. The coffee consumption was classified by the average frequency of intake, such as less than 1 cup/day, 2-3 cups/day, more than 5 cups/day). Possible confounding effects of age, sex, smoking and alcohol drinking were controlled by multiple logistically regressive analysis. Results : After adjusting age and sex, coffee consumption significantly increased risk factors of stroke(${\leq}$1 cup/day OR=1.018, 95% CI=0.631-1.644; 2-3 cup/day OR=1.782, 95%CI=1.032-3.079;${\geq}$5 cup/day OR=1.210, 95% CI=0.588-2.490). When other factors were controlled, the risk factors of stroke were associated with alcohol drinking, whereas no significant association was observed with coffee consumption. Conclusion : Coffee consumption is not a major risk factor of causing stroke in this study. Prospective and cohort study on the association between coffee consumption and the possibility of getting strokes among the Korean population will be needed in the future.

암환자의 방사선 요법 및 화학요법 치료 후 발생된 백혈구감소증의 치료에 관한 중의학 임상논문의 문헌적 고찰

고성규,정용수,부송아,박경훈,선승호,Ko, Seong-Gyu,Jung, Yong-Soo,Bu, Song-Ah,Park, Kyoung-Hoon,Sun, Seung-Ho 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Objective : We conducted this study to analyze some of the trends of treatments from the recent Chinese medical journals and contribute them to the oriental medical experiments and clinical research for the future. Methods : By referring to the Chinese medical journals that were published in China from 1999 to March, 2002, we analyzed the effective rates on frequency, methods, medical treatment, and diseases. Result : The average effective rate was 90.93%, which was very high. Lately, there have been no big changes in the methods of treatment. The methods of coordinating stomach-Qi, supplying Yin element, replenishing bone marrow, tonifying essence of life, and removing blood stasis are used by means of reinforcing Qi, producing blood, tonilying spleen, and replenishing the kidney. Conclusions : The decreased in bone marrow and leucopenia, and the side effects of radiotherapy and chemotherapy were more effectively treated when we used Korean oriental medical treatments. In addition, more Korean oriental medical experiments and clinical studies are needed in Korea, in the future.

뇌졸중의 위험요인에 대한 환자-대조군연구 -과거병력, 생활습관, 혈청지질 및 비만요인을 중심으로-

고성규,정용수,박경훈,부송아,Ko, Soeng-Gyu,Jung, Yong-Soo,Park, Kyoung-Hoon,Bu, Song-Ah 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3

Objects: The purpose of this case-control study was done to examine the relationship between stroke prevalence and the anthropometric indices(body mass index(BMI), modified Broca's method(Broca's index), waist circumference(WC), waist-hip ratio(WHR)), dyslipidemia, past medical history(heart disease, hypertension, diabetes mellitus(DM)), life-style factors(smoking, drinking) in Korean adults. Methods : The study group consisted of neurologically confirmed 116 stroke patients as the case group and 116 non-stroke patients as control group. Obesity were defined as $BMI{\geq}25kg/m^2,\;Broca's\;index{\geq}30%$, WC >94cm in male and WC >80cm in female, $WHR{\geq}0.9$ in male and $WHR{\geq}0.8$ in female. Oyslipidemia were defined as total $cholesterol{\geq}200mg/dl,\;triglyceride{\geq}200mg/dl,\;HDL-cholesterol {\leq}35mg/dl,\;LDL-cholesterol{\geq}160mg/dl$. Information on life-style factors and past medical history was obtained from personal interview. The analysis of the data was done by means of chi-square test(Pearson's chi-square test, Fisher's exact test) and student t-test. Results: The results were as follow. In the study group: Hypertension had a 4:05 odds ratio, Broca's $index{\geq}30%$ had a 1.98 odds ratio, WC >94cm in male had a 2.17 odds ratio, WC >80cm in female had a 2.80 odds ratio, $WHR{\geq}0.9$ in male had a 4.66 odds ratio, $WHR{\geq}0.8$ in female had a 5.35 odds ratio, but heart disease, DM, life-style factors, serum lipid and 8MI had no direct relationship with odds ratio(nonsignificant). By student t-test, risk factors for stroke were found to be total cholesterol(p=0,025), LDL-cholesterol(p=0.013), WC(p=0.000) and WHR(p=0.000). Conclusions: This study suggests that people should be advised to control hyperlitension, hyperlipidemia and obesity since these carry a risk of stroke.

소뇌기능이상의 임상양상을 특징으로 보인 뇌교부출혈 환자 1례

이유경,공경환,용형순,고성규,부송아,Lee, You-Kyung,Kong, Kyung-Hwan,Yong, Hyung-Soon,Ko, Seong-Gyu,Bu, Song-Ah 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5

I experienced a case of a patient with clinical features of cerebellar dysfunction in the intracranial hemorrhage which encroached the basis of lower pontine and all parts of pontine tegmentum. So I report this case with bibliographical inquiry. In addition, I applied the treatment of Oriental medicine to sequelae of intracranial hemorrhage like disorders of eye movement, central dizziness, cerebellar tremor and ataxias but the effect did not meet my expectation. I anticipate more clinical studies and reports on this hereafter.

血證에 관한 中醫學 臨床論文 分析(2) : 해혈, 육혈, 뇨혈, 혈정, 안와내출혈

정한수,용형순,부송아,고성규 대한한방성인병학회 2000 韓方成人病學會誌 Vol.6 No.1

Objective : The purpose of this study was to classify the symptoms of hyeal-jeung(血證) and analyze the tend of treatments in the chinese medical journal Method : This study referrenced the chinese medical magazine that has been published in china for two years, 1996-1997 and the data is classified by the kind of disease and is analyzed by the treatment frequency, treatment way, treatment drug, and the rate of recovery from the disease. Result : Of the hemoptysis(咳血), on the principle, recipe and medicine of treatment, clearing away lung-fire(淸肺), clearing away liver-fire(淸肝), and eliminating stasis(化瘀) was used more then hemostatic(止血). The recovery rate of hemoptysis was more efficient in the oriental-western treatment than pure oriental treatment. Of the epistaxis(??血), the overall mean rate of recovery was 96.8%, and purzing intense heat(瀉火), removing heat form the blood(양혈) and reducing fever(淸熱) was uased generally chosen other than the principle of treatment. Of the hematuria, the treatment was regard on the weakness of the spleen and stomach(脾胃具損). Of the bloody semen, the overall mean rate of recovery was 100%. Of bleeding in the eyeball, there was more efficient the oriental-western treatment than pure oriental treatment. Conclusion : Clinically we severally experienced on attack of hyeal-jeung(血證), but we have not much of data or journal related to this symptoms in our country. So, this study try to examine the symptoms of hyeal-jeung(血證) through chinese medical journal, From the above result, it was concluded that oriental medical treatments show efficient effect in treating hemorrhagic disease and it will be required more investigation of clinical examination in hemorrhagic disease in our country.