유방암의 전신치료요법

박흥규 ( Heung Kyu Park ),김현영 ( Hyun Young Kim ),김혜경 ( Hye Kyoung Kim ) 대한임상종양학회 2006 Korean Journal of Clinical Oncology Vol.2 No.3

벼 유기재배 시 녹비작물 처리에 의한 작물의 생육, 수량 및 품질 비교

차광홍,오환중,박흥규,안규남,박노동,정우진,Cha, Kwang-Hong,Oh, Hwan-Jung,Park, Heung-Gyu,An, Kyu-Nam,Park, Ro-Dong,Jung, Woo-Jin 한국유기농업학회 2011 韓國有機農業學會誌 Vol.19 No.1

벼 재배포장에서 녹비작물의 이용성을 조사하고자 보리와 헤어리베치를 적용하여 시험구를 배치하였다. 무농약 4년차 벼 재배포장에서 벼 수확 후 재배한 보리를 녹비작물로 이용한 처리구(보리녹비구), 보리와 헤어리베치를 혼파한 다음 녹비작물로 이용한 처리구(보리+헤어리베치 녹비구), 벼 수확 후 녹비작물을 재배하지 않은 방임구(나지방임구)와 보리를 재배한 후 수확한 처리구(관행구)에서 호품벼를 2009년 6월 15일 평당 60주를 기준으로 기계 이앙하여 얻어진 시험결과를 요약하면 다음과 같다. 1. 간장과 수장은 관행구가 조금 길었으며, 처리간에는 차이가 없었다. 백미 수량은 관행구를 100%로 볼 때 보리녹비구가 90.3%, 보리+헤어리베치 녹비구가 95.9%로 나타났다. 2. 벼 품질 평가에서 보리녹비구와 보리+헤어리베치 녹비구의 단백질 함량은 관행구 6.6%에 비해 5.7%로 낮았다. 아밀로스함량은 모든 처리구에서 18.8~19.1% 범위로 유사한 경향을 보였다. 백도는 관행구 37.7에 비해 보리녹비구 38.9와 보리+헤어리베치 녹비구 39.1로 약간 높게 나타났다. 3. 취반미 윤기치는 관행구 77.6에 비해 보리수확구가 82.0, 나지방임구가 83.8로 양호하게 나타났다. 4. 완전립율이 나지방임구는 95.5%인 반면에 관행구, 보리녹비구, 보리+헤어리베치 녹비구에서 93.8~94.2% 범위로 약간 낮게 나타났다. 쇄립율도 유사한 경향이었으며 분상질립율은 관행구가 1.7%로 가장 높았다. 5. 본 시험에서 발생된 병해는 잎도열병, 이삭도열병, 잎집무늬마름병이었다. 해충으로는 굴파리류, 혹명나방, 줄점팔랑나방, 끝동매미충이었다. 기상환경이 병해충발생에 불리한 조건으로 경과되어 병해충 발생이 전반적으로 적었으며 처리간에도 유의적인 차이를 나타내지 않았다. To investigate a comparison of rice yield and quality by a utilization of green crops using barley and hairyvetch, this study was carried out in rice (Oryza sativa L.) organic cultivation field. Convention barley harvest (CBH), Green barley crop (GBC), Green barley+Green Hairyvetch crop (GB+HVC), and Non-Green crop (NGC) were treated in rice cultivation field. The results obtained as following: 1) Culm length and pancile length in Convention barley harvest (CBH) cultivation were longer than organic cultivation but were not significant difference in all treatments. Yields of milled rice in Green barley crop (GBC) and Green barley+Green Hairyvetch crop (GB+HVC) were by 90.3% and 95.9%, respectively. 2) Protein contents in Green barley crop (GBC) and Green barley+Green Hairyvetch crop (GB+HVC) were by 5.7% lower than 6.6% in Convention barley harvest (CBH) cultivation. Amylose contents in all treatment were similar as range 18.8% to 19.1%. Whiteness contents in Green barley crop (GBC) and Green barley+Green Hairyvetch crop (GB+HVC) were slightly higher by 38.9% and 39.1%, respectively, than 37.7% in Convention barley harvest (CBH) cultivation. 3) Palatability values in Barley harvest (BH) and Non-Green crop (NGC) were slightly higher by 82.0 and 83.8, respectively, than 77.6 in Convention barley harvest (CBH) cultivation. 4) Head rice in Non-Green crop (NGC) was 95.5%, while that of Convention barley harvest (CBH), Green barley crop (GBC), and Green barley+Green Hairy-vetch crop (GB+HVC) were slightly low as range 93.8% to 94.2%. White core and belly rice in Convention barley harvest (CBH) cultivation was the highest level by 1.7%. 5) Leaf blast, neck blast, sheath blight, rice stem maggot, rice leaf roller, rice leaf-tier, and green rice leafhopper were occurred lightly in rice field.

점막하 위암에서 림프절 전이에 영향을 미치는 인자

고성주,서재환,박흥규,이훈규,조승연,이운기,이정남,이영돈,조현이,Ko Seong Ju,Suh Jae Hwan,Park Heung Kyu,Lee Hoon Gyu,Cho Seung Yeon,Lee Woon Gi,Lee Jeong Nam,Lee Young Don,Cho Hyun Yee 대한위암학회 2001 대한위암학회지 Vol.1 No.3

Purpose: Submucosal gastric carcinomas metastasize to lymph nodes more often than the intramucosal gastric carcinomas. The objectives of this study are to clarify the characteristics of submucosal gastric carcinomas, especially in reference to the status of lymph node metastasis, and to explore the possibility of a minimally invasive operation. Materials and Methods: The clinicopathologic features of 88 patients with submucosal gastric carcinoma, all of whom were treated with a $D_{2}+\alpha$ gastrectomy between January 1994 and December 1999, were examined retrospectively with respect to the status of lymph nodes. The size, depth of submucosal invasion, histologic differentiation, location,and macroscopic finding of the tumor were investigated in association with the presence or the absence of lymph node metastasis. Results: Among the 88 patients, 15 ($17.05\%$) had lymph node metastasis, and the status of metastasis was significantly correlated with tumor size and depth of submucosal invasion. The frequency of metastasis was $0\%$ (0/7) of up to 1.0 cm and $18.5\%$ (15/81) over 1.0 cm in size (p=0.034) and $6.1\%$ (2/33) of up to 1.0mm and $23.6\%$ (13/55) over 1.0 mm in depth of submucosal invasion (p=0.042). Conclusion: The tumor size and depth of submucosal invasion are useful indicators of lymph node metastasis in submucosal gastric carcinoma. A minimally invasive operation can be applied for submucosal gastric carcinoma up to 1.0 cm in size Further studies are needed to limited surgery for depth of submucosal invasion.

벼 친환경재배에서 왕우렁이의 잡초방제효과 및 피해

권오도(Oh Do Kwon),박흥규(Heung Gyu Park),안규남(Kyu Nam An),이인(Yeen Lee),신서호(Seo Ho Shin),신길호(Gil Ho Shin),신해룡(Hae Ryoung Shin),국용인(Yong In Kuk) 韓國雜草學會 2010 Weed&Turfgrass Science Vol.30 No.3

본 연구는 벼 친환경재배에서 왕우렁이의 크기, 투입시기 및 투입량에 따른 잡초방제효과와 벼에 대한 피해율을 구명하여 가장 적합한 잡초관리법을 찾고자 수행하였다. 이앙 후 5, 10 및 15일에 투입한 왕우렁이에 의한 잡초방제 효과는 각각 98%, 89% 및 58%로서 투입시기가 늦어질수록 잡초방제 효과는 낮아지는 경향을 보였다. 또한 왕우렁이 단독처리보다는 쌀겨와 체계처리시 잡초방제 효과는 증가되는 것으로 나타났다. 왕우렁이 투입시기가 늦어질수록 방제가 어려운 잡초는 여뀌, 피, 올챙이고랭이, 물달개비 등이었다. 효과적인 잡초방제를 위해 적합한 왕우렁이 중패의 투입시기 및 투입량은 이앙 후 5일 이내에는 3㎏ 10a-1, 이앙 후 10일에는 6~7㎏이었고 이앙 후 15일에는 7㎏이었다. 따라서 왕우렁이 투입시기가 늦어질수록 투입량을 늘려야 할 것으로 기대된다. 왕우렁이 치패의 투입시기 및 투입량은 써레질직후에 1㎏(2,000개)10a-1이었으며 피, 물달개비, 여뀌바늘, 알방동사니, 미국외풀, 올챙이고랭이, 올방개, 벗풀 등 모두100% 방제가 가능하였다. 왕우렁이 중패(3㎏ 10a-1)에 의한 벼의 하위엽 및 분얼경에5~7% 정도 피해가 나타났으며, 치패 1㎏(2,000개) 10a-1의 경우는 묘령에 관계없이 벼의 하위엽에 1%정도의 피해를 보였다. 그러나 왕우렁이의 크기나 투입량별로 처리한 후 조사한 벼의 초장과 분얼수에는 유의적인 차이를 보이지 않았다. 따라서 친환경벼 재배지에서 잡초방제효과, 벼 피해율 및 왕우렁이 비용 등을 고려할 때 왕우렁이 치패 1㎏ 10a-1(2,000개)를 써레질 직후에 투입하는 것이 가장 적합할 것으로 판단되었다. The objective of this research was to discover the best method for weed management in environment-friendly rice paddy fields through the study on the effect of weed control and injury levels of rice plants as affected by size, input time, and input amount of golden apple snail (GAS). The efficacy of weed control as affected by GAS when applied at 5, 10, and 15 days after transplanting (DAT) was 98, 89, and 58%, respectively. The efficacy of weed control had declined as late the input time of GAS. On the other hand, the efficacy of weed control as affected by rice bran followed by GAS treatment was higher than by GAS treatment alone. Weed species such as Persicaria hydropiper, Echinochloa crus-galli, Scirpus juncoides, and Monochoria vaginalis were not completely controlled by GAS when applied late. Input amount and time of adult GAS (70 days after hatching) for effective weed control were 3 ㎏ 10a-1 at 5 DAT, 6-7 ㎏ 10a-1 at 10 DAT, and 7 ㎏ 10a-1 at 15 DAT. Input time and amount of young GAS (35 days after hatching) for effective weed control were 0 day after harrow (DAH) and 1 ㎏ 10a-1, respectively. The young GAS when applied 0 DAH at 1 ㎏ 10a-1 provided 100% control of P. hydropiper, E. crus-galli, S. juncoides, M. vaginalis, Ludwigia prostrata, Eleocharis kuroguwai, Sagittaria trifolia and Cyperus difformis. The rice foliar injury caused by adult (3 ㎏ 10a-1) and young (1 ㎏ 10a-1) GAS were 5-7% and 1% respectively. There was no significant difference in rice injury by size and input amount of GAS on plant height and number of tiller. These data indicate that the young GAS when applied 1 ㎏ 10a-1 at 0day after harrow was the best method for weed management in environment-friendly rice paddy fields.

분화 갑상선암의 경부 림프절 전이 및 원격 전이 발견에 있어서 <SUP> 99m</SUP>Tc-tetrofosmin, <SUP>131</SUP>I Whole Body Scan과 Thyroglobulin 혈중 농도의 의의

송상현(Sang Hyun Song),박흥규(Heung Kyu Park),박연호(Yeon Ho Park),이정남(Jeong Nam Lee),김종호(Jong Ho Kim),이영돈(Young Don Lee) 대한외과학회 2002 Annals of Surgical Treatment and Research(ASRT) Vol.63 No.5

T1 침윤성 유관암에서 액와부 림프절 전이에 영향을 주는 인자들

박승연 ( Seung Yeon Park ),박흥규 ( Heung Kyu Park ) 대한임상종양학회 2010 Korean Journal of Clinical Oncology Vol.6 No.2

Background: Due to the increment of general interest in breast cancer and the early screening examination, the rate of early breast cancer is relatively increasing, along the rate of the successful treatment. Even at the earlier stage of breast cancer, the process of axillary lymph node metastasis is significant for treatment and prognosis of the cancer. Therefore, the aim of the study is to identify the factors that influence the lymph node metastasis among the patients with T1 breast cancer. Methods: Between January 2003 and May 2008, 204 patients diagnosed as infiltrating ductal carcinoma after the breast cancer resection at Gachon University Gil Hospital were enrolled in this study. Each patient`s age, size and location of cancer, number of tumor, tissue and nuclear grade, infiltration of lymph vessels, immunohistochemistry test result (ER, PR, p53, HER2, Ki67, etc.), and axillary lymph node status were compared. Results: 10 out of 204 patients had cancer smaller than 0.5 cm(T1a), 22 patients had cancer size larger than 0.5 cm and smaller than 1cm(T1b), and 172 patiens had cancer size larger than 1cm(T1c). For the rate of axillary lymph node metastasis, in the group of T1a, 1/10 (10%) patients showed axillary lymph node metastasis, in T1b, 2/22(9.1%) patients showed axillary lymph node metastasis and in T1c, 54/172(31.3%) patients showed axillary lymph node metastasis. The result distinguished by the size of the cancer was statistically significant (p=0.039). The number of tumor was sorted as 1, 2, and more than 3, and each integer was 179, 17, and 8 patients. The rate of axillary lymph node metastasis according to the number of tumor was 48/179 (26.8%) with 1 tumor, 5/17(29.4%) with 2 tumors, and 4/8 (50%) with more than 3 tumors. This result distinguished by the number of tumor was also statistically significant (p=0.007). Also, Lymphovascular invasion was statistically significant(p=0.001). The rate of axillary lymph node metastasis did not show the statistical significance with the age of patients, location of cancer, tissue and nuclear grade, and immunohistochemistochemical staining result. Conclusion: It is considered that the size and the number of tumor, and lymphovascular infiltration are the significant factors influencing axillary lymph node metastasis of the T1 invasive ductal carcinoma. Furthermore, it is expected that the size and the number of tumor in preoperative ultasonography will be helpful determining the axillary lymph node dissection.

태변성 복막염 15예의 임상적 고찰

김강석(Kang Seok Kim),박흥규(Heung Kyu Park),박연호(Yeon Ho Park),민승기(Seung Ki Min),조승연(Seung Yeon Cho),이운기(Woon Ki Lee),이영돈(Young Don Lee) 대한외과학회 2002 Annals of Surgical Treatment and Research(ASRT) Vol.62 No.1

벼 친환경재배에서 다양한 유기자원별 잡초방제효과

권오도(Oh Do Kwon),박흥규(Heung Gyu Park),안규남(Kyu Nam An),이인(Yeen Lee),신서호(Seo Ho Shin),신길호(Gil Ho Shin),신해룡(Hae Ryoung Shin),국용인(Yong In Kuk) 韓國雜草學會 2010 Weed&Turfgrass Science Vol.30 No.3

본 연구의 목적은 벼 친환경재배 농가에서 사용되고 있는 다양한 유기자원들에 대한 잡초방제 효과와 문제점을 구명하여 친환경 벼 재배지에서 잡초관리기 술을 확립하기 위하여 수행하였다. 친환경 벼 재배지 에서 잡초발생밀도와 종류가 서로 다른 조건하에서 다양한 유기자원을 처리한 결과 왕우렁이, 종이멀칭 및 기계제초의 잡초방제 효과는 유사하였으나 쌀겨 및 EM당밀처리에서는 잡초발생량이 많은 처리구에서 적은 처리구에 비해 잡초방제 효과가 높았다. 일반적으로 유기자원처리에 의한 잡초방제 효과는 왕우렁이(97~100%) > 종이멀칭(93~98%) > 기계제초(73~75%) > 쌀겨(15~80%) > 당밀(7~31%) 순이었다. 왕우렁이는 여뀌를 제외하고 모든 초종에 대하여 높은 방제효과를 보였고, 종이멀칭도 피와 여뀌바늘, 올방개 등이 다소 발생하나 비교적 우수한 효과를 보였으며, 기계제초는 잡초종에 관계없이 전반적으로 70%의 방제효과를 보였다. 쌀겨/기계 및 EM/기계의 체계처리에 의한 잡초방제 효과는 각각의 단독처리에 비해 차이가 없었으나 쌀겨/ 왕우렁이 및 EM/왕우렁이 체계처리에 의해 100% 방제효과를 보였다. 다양한 유기자원 처리에 의한 벼 피해율은 왕우렁이와 기계제초(10~20%) > 쌀겨(10~15) > 종이멀칭 및 EM당밀(5~7%) 순으로 높았다. 피해증상은 유기자원에 따라 다소 다르지만 생육저해, 분얼경 가해 및 결주 등이다. 왕우렁이, 쌀겨, 당밀 및 종이피복의 잡초방제 비용은 제초제에 사용에 소요된 비용보다 각각 2.1, 3.1, 2.3 및 13.2배 높게 나타났다. 따라서 다양한 유기자원 중 친환경 벼 재배지에서 왕우렁이를 이용하여 잡초를 방제하는 것이 가장 적합할 것으로 사료된다. 추후 왕우렁이 농법 사용시 발생되는 제초비용과 벼 피해를 줄일 수 있는 연구가 수행되어야 할 것이다. The objective of this research was to find out the weed management techniques in environment-friendly rice paddy fields through the study on herbicidal effects and problems of various organic material. This experiment was conducted under different conditions of weed species and weed densities in environment-friendly rice paddy fields. There was no difference in weedy efficacy on golden apple snail (GAS), paper mulching (PM), and machine weeding (MW) between low and high weed densities. However, the effect of weed control in rice bran (RB) and effective microorganism (EM) + molasses was higher in high weed density than in low weed density. In general, the effect of weed control a affected by various organic materials was in the order of GAS (97-100%) > PM (93-98%) > RB (15-80%) > EM (7-31%). GAS provided excellent control of all weed species tested except for Persicaria hydropiper. PM gave acceptable control of the weed species except for Echinochloa crus-galli, Ludwigia prostrata, and Eleocharis kuroguwai. However, MW gave fair control (70% biomass reduction) of all weed species tested. BR followed by MW or EM followed by MW treatments had similar effect on weed control compared to each treatment alone. However, BR followed by GAS or EM followed by GAS provided 100% control of weed species tested. The level of rice foliar injury caused by various organic materials was in the order of GAS and MW (10-20%) > RB (10-15%) > PM and EM (5-7%). Typical symptoms of organic materials are wilting, inhibition of growth, missing hill, and reduction of tiller. Cost for weed control of GAS, RB, EM, and PM were 2.1, 3.1, 2.3 and 13.2 times higher than that of the herbicide. These data indicate GAS was the best method for weed management in environment-friendly rice paddy fields. Further study is required to elucidate the mechanisms underlying the rice injury as affected by GAS.

천공성 십이지장 궤양 환자에서 사망률에 영향을 주는 예후인자들에 대한 분석

서재환(Jae Hwan Seo),박흥규(Heung Kyu Park),박연호(Yeon Ho Park),이훈규(Hoon Kyu Lee),이운기(Woon Ghi Lee),조승연(Seung Yeon Cho),이정남(Jeong Nam Lee),이영돈(Young Don Lee) 대한외과학회 2001 Annals of Surgical Treatment and Research(ASRT) Vol.60 No.4

벼 담수직파논에서 새섬매자기와 미국외풀 발생밀도에 따른 쌀 수량 감소와 경제적 방제수준

권오도(Oh Do Kwon),안규남(Kyu Nam An),이인(Yeen Lee),신서호(Seo Ho Shin),박흥규(Heung Gyu Park),신해룡(Hae Ryoung Shin),문병철(Byeong Cheol Moon),국용인(Yong In Kuk) 韓國雜草學會 2011 Weed&Turfgrass Science Vol.31 No.4

벼 담수직파재배에서 잡초 경합밀도별 쌀 수량 감소는 새섬매자기의 경우, ㎡당 24본 이상에서, 미국외풀은 48본 이상에서 유의적으로 낮아졌으며 새섬매자기(㎡당 192본)와 미국외풀(㎡당 386본)의 최대 경합밀도에서 각각 43%, 22% 정도 감소되었다. 새섬매자기 발생밀도에 따른 수량 예측 모델식은 Y=531.3kg/(1+0.003931x), r²=0.964, 미국외풀은 Y=547.0kg/(1+0.000792x), r²=0.922으로 나타나 벼에 대한 새섬매자기의 경합력이 미국외풀 보다 약 5.0배 정도 큰 것으로 나타났다. 또한, Cousens(1985) 방법에 따른 초종별 경제적 방제수준은 새섬매자기는 ㎡당 7.2본, 미국외풀은 34.9본으로 나타나 이에 비해 잡초 발생밀도가 높을 때는 방제하는 것이 경제적으로 유리할 것으로 판단되었다. This study was conducted to find the levels of reduction in rice yield and to determine economic threshold levels as affected by densities of Scirpus planiculmis and Lindernia dubia in wet seeding rice cultivation. In wet seeding rice cultivation, yield of rice in densities of S. planiculmis (192 per m²) and L. dubia (384 per m²) was reduced by 43 and 22%, respectively. Relationship between rice yield and densities of weeds were predicted with these equations of Y=531.3kg/(1+0.003931x), r²=0.964 for S. planiculmis and Y=547.0kg/(1+0.000792x), r²=0.922 for L. dubia. According to Cousens" method, economic threshold densities of S. planiculmis and L. dubia were calculated by 7.2 and 34.9 per m², respectively. This result indicated that yield of rice in wet seeding rice cultivation could be reduced by over economic threshold densities of S. planiculmis and L. dubia.