피치 정보를 이용한 GMM 기반의 화자 식별

박태선,한민수,Park Taesun,Hahn Minsoo 대한음성학회 2003 말소리 Vol.47 No.-

This paper describes the use of pitch information for speaker identification. The recognition system is a GMM based one with 4 connected Korean digits speech database. The mean of the pitch period in voiced sections of speech are shown to be ,useful at discriminating between speakers. Utilizing this feature with Gaussian mixture model in the speaker identification system gave a marked improvement, maximum 6% improvement comparing to the baseline Gaussian mixture model.

The olfactory receptor as a potential target for skin barrier dysfunction

박태선 ( Taesun Park ) 한국피부장벽학회 2022 한국피부장벽학회지 Vol.24 No.2

Olfactory receptor (OR) constitutes the largest subfamily of G-protein-coupled receptors and was once thought to be exclusively present in the olfactory epithelium. However, recent studies have revealed that OR is a general chemoreceptor found in diverse tissues (e.g., skin, liver, muscle, and prostate) and associated with various physiological conditions. In the present study, we aimed to characterize the OR expression profile in human epidermal keratinocytes (HaCaT) exposed to ultraviolet radiation or inflammation, two well-known stimuli for skin barrier dysfunction. We first confirmed that major olfactory signaling components, including G protein subunit alpha L (GNAL), Ric8b, and adenylate cyclase type 3 (ADCY3), were all expressed in keratinocytes. Also, the twelve ectopic ORs were more highly expressed in UV-irradiated or inflamed keratinocytes than in untreated keratinocytes. Among twelve ORs, OR2A4 and OR10H1 were found to promote barrier dysfunction in the presence of their known ligands. At the same time, we found several other scent compounds upregulating the expression of skin barrier genes including filaggrin, although their corresponding receptors are still unknown. These findings show the potential of OR as a novel target for skin barrier abnormalities.

On the Causes of Passives in English, Korean and Chinese from a Corpus-Based Approach

Taesun Park(박태선) 언어과학회 2020 언어과학연구 Vol.0 No.93

This study examines the factors of passive voice in Korean, English, and Chinese from authentic data through the use of a corpus. The corpora used in this study are NIKLC for Korean, BNC for English, and ECPC for Chinese. The result shows that in English, topicality is the highest factor, connectedness is the second factor, and circumstances dependency is the third factor. In Korean, topicality is the highest factor, circumstances dependency is the second factor and connectedness is the third factor. In Chinese, affectedness is the highest factor, connectedness is the second factor, and topicality is the third factor. Agent omission phenomenon is a common characteristic in the three languages. Circumstances dependency, which is characteristic of Korean passive, is the lowest in English. Though the corpora used in this study may not be completely perfect in their content, this research has its value in the fact that it tries to compare the three languages through the use of a corpus.

영어 한국어 수동문 사용의 빈도와 요인에 관한 연구: 성경 요한복음 한영번역본을 활용

박태선(Park, Taesun) 언어과학회 2021 언어과학연구 Vol.- No.98

The present study aims to investigate the causes of the passive in English and Korean from the Gospel of John to find out what their characteristics are in terms of the semantic linguistic view. The result shows that in English, 145 passive sentences are found out of 1129 sentences. 111 passive sentences are classified as topicality and 14 passive sentences as connectedness. In addition, there exist 118 short passives, or agent omission, whereas there exist 7 long passives with by-agent. In Korean, 94 passive sentences are found out of 1462 sentences. 53 passive sentences are classified as topicality and 29 passive sentences as connectedness and 14 passive sentences as circumstances dependency. There exist 83 short passives, or agent omission, whereas there exist 11 long passives with by-agent. The findings show that the frequency of the passive in English is much higher than that of Korean. Topicality is the highest factor of the passive and connectedness is the second highest factor in both languages. In Korean, circumstances dependency is an important characteristic.

식이내의 타우린 보강이 무콜레스테롤 식이를 섭취하는 흰쥐의 혈액과 간의 지질수준에 미치는 영향

박태선(Park Taesun),이경신(Lee Kyungshin) 韓國營養學會 1997 Journal of Nutrition and Health Vol.30 No.10

지역별 홍수피해특성을 고려한 홍수피해지표 개발

박태선(Park Taesun),여창건(Yeo Chang Geon),최민하(Choi Minha),이승오(Lee Seung Oh) 대한토목학회 2010 대한토목학회논문집 B Vol.30 No.4B

시군구간의 잠재적 홍수피해 위험성을 계량적으로 비교할 수 있다면 지역단위의 치수계획을 수립하거나 국가의 치수예산 집행 우선순위를 결정하는데 큰 도움이 된다. 본 연구에서는 지역별 홍수피해의 잠재적 위험성을 손쉽게 파악할 수 있는 홍수피해지표(Flood Damage Index : FDI)를 제안하였다. 홍수피해지표는 홍수피해에 영향을 미치는 직 · 간접적 요인들을 자연적 요인, 사회적 요인, 정책적 요인, 시설적 요인이라는 네 가지로 구분한 후, 이들을 대표하는 11개 주요 인자들을 선정하고, 인자별 가중치와 무차원 인자값들을 곱하여 합산한 지표이다. 이 지표를 이용하여 전국 229개 시군구의 잠재적 홍수피해 위험성을 비교하였고, 지역별 홍수발생요인도 분석하였다. 연구결과는 보다 합리적인 치수대책수립에 활용될 수 있다. It would be helpful to evaluate the potential flood damage and compare quantitatively with each other when establishing the regional flood countermeasure and determining the execution of the restoration works and emergency action plans. The Flood Damage Index (FDI) in Korea, possible to estimate localized potential risks caused by flood damages, therefore, was proposed in this study. It was considered with the scale of regional flood damages including the regional characteristics and quantitative grounds. First, the four significant causes were categorized as natural, social, politic, and facilitative ones. And the eleven selected factors representing four causes were determined. Finally, the FDI was obtained by the weighting linear summation of the corrected 11 factors multiplied by the weighting values based on the professional questionnaires. Employing the FDI, the potential risk analysis about flood damages for 229 cities and counties in Korea was conducted. These results would be utilized as the essential basis for more rational and practical countermeasures and plans against flood damage.

콜레스테롤과 타우린보강이 흰쥐 간의 총지방산 및 인지질지방산 조성에 미치는 영향

박태선(Taesun Park),오주연(Joo-Yeon Oh),김인숙(In-Sook Kim),엄영숙(Young-Sook Um) 한국식품영양과학회 1999 한국식품영양과학회지 Vol.27 No.6

본 연구에서는 콜레스테롤과 타우린보강이 간조직의 지방산 조성 및 대사에 미치는 효과를 평가하고자 흰쥐를 대상으로 대조식이(CD), 고콜레스테롤식이(HCD; CD+1.5% 콜레스테롤), 또는 고콜레스테롤/고타우린식이(HCHTD; HCD+1.5% 타우린)를 5주간 섭취시켰다. 실험식이에 따른 간의 지방산 조성의 변화는 총 지질과 인지질에서 매우 유사한 패턴으로 나타났다. 즉, HCD군의 경우 CD군에 비해 간의 총 지질과 인지질에 함유된 포화지방산 조성은 유의하게 감소한 반면 단일 불포화지방산의 조성은 증가하였으며, 고콜레스테롤 식이에 타우린을 보강해준 결과(HCHTD) 역의 효과가 나타나 HCD군에 비해 포화지방산의 조성은 유의적으로 증가하였고 단일불포화지방산의 조성은 오히려 감소하였다. 간의 총 지질과 인지질에 함유된 총 다가불포화지방산의 조성은 실험식이에 의해 유의적인 영향을 받지 않았으나, 개별 ω3계 및 ω6계 지방산은 종류에 따라 유의적인 증감현상이 관찰되었다. 즉 ω3계 및 ω6계 지방산대사의 전구체인 α-LNA(18 : 3ω3), EPA(20 : 5ω3), LA(18 : 2ω6) 및 20 : 3ω6의 조성은 HCD군이 CD군에 비해 유의적으로 증가하였으나 탄소수가 더 긴 22 : 5ω3, DHA(22 : 6ω3), AA(20 : 4ω6) 및 22 : 4ω6의 조성은 대조군에 비해 HCD군에서 더 낮았다. HCD는 간에서 ω6계 지방산의 △5 desaturation(20 : 3ω6⇒수 20 : 4ω6) 및 △4 desaturation(22 : 4ω6⇒22 : 5ω6) 지표를 저하시켰으나 ω3계 지방산의 elongation(20 : 5ω3⇒22 : 5ω3) 지표를 증가시켰고, HCHTD군에서는 HCD군에서 관찰된 변화가 상쇄되는 경향이 나타났다. 이상의 결과들은 콜레스테롤 및 타우린보강이 간의 인지질지방산 조성에 변화를 초래하므로써 간세포막의 물리적 특성에 영향을 미치고, microsome의 효소활성을 조절하므로써 간접적으로 체내 지질대사에 관여할 수 있는 가능성을 제시해 주는 것이다. Effects of dietary cholesterol and taurine supplementation on hepatic total and phospholipid fatty acid compositions were evaluated in rats fed one of the following semisynthetic diets for 5 weeks : control diet(CD, cholesterol-free and taurine-free diet); high cholesterol diet(HCD, CD+1.5% cholesterol); high cholesterol, high taurine diet(HCHTD, HCD+1.5% taurine). Diet-induced changes in hepatic total fatty acid compositions were very similar to those in hepatic phospholipid fatty acid compositions. The HCD significantly decreased the percentage of total saturated fatty acids(SFA), and increased the percentage of total monounsaturated fatty acids(MUFA) of hepatic total lipids and phospholipids as compared to the values for the control rats(p<0.001). HCHTD significantly elevated the percentage of ΣSFA and lowered the percentage of ΣMUFA compared to the values for the HCD(p<0.001). Percentages of hepatic total and phospholipid 18 : 3ω3, 20 : 5ω3, 18 : 2ω6 and 20 : 3ω6 were significantly higher in rats fed the HCD than the values for the control rats, and the percentages of their elongation and de saturation products(22 : 5ω3, 22 : 6ω3, 20: 4ω6, 221 : 4ω6 and 22 : 5ω6) were significantly lower in rats fed the HCD compared to those for the control rats. HCD significantly lowered the △5 desaturation(20 : 3ω6⇒20 : 4ω6) and △4 desaturation(22 : 4ω6⇒22 : 5ω6) indices, and the elongation index of ω3 fatty acid(20 : 5 ω3⇒22 : 5ω3) in rat liver. HCHTD reversed the cholesterol-induced changes in the compositions of ω3 and ω6 fatty acids. These results suggest the possibility that dietary cholesterol and taurine supplementations affect plasma and liver lipid levels, at least in part, by changing the hepatic phospholipid fatty acid compositions and thereby modulating the physical characteristics of the membrane and the activities of microsomal enzymes involved in lipid metabolism.

식품의 아미노산 정량을 위한 단일가수분해 방법의 개발

박태선(Taesun Park) 한국식품영양과학회 1997 한국식품영양과학회지 Vol.26 No.3

본 연구의 결과를 요약하면 여러가지 식품군과 복합음식의 아미노산 함량을 정량하는데 있어서 단일가수분해 방법은 전통적인 6N HCl을 사용하는 가수분해와 함황아미노산의 정량을 위한 performic acid 산화과정을 대신하여 사용될 수 있을 것으로 생각된다. 단일가수분해를 실시하여 얻은 cysteine, cystine과 methionine의 농도는 performic acid로 산화시킨 후 가수분해하여 얻은 수치에 비해 대부분의 식품 및 복합음식시료에서 유의적으로 더 높게 나타났다. 반면 0.2%의 tryptamine이 첨가된 상태에서 단일가수분해를 실시하는 경우 여전히 상당량의 tryptophan이 파괴되었으므로 식품과 복합음식료에서의 tryptophan 정량분석을 위해서는 전통적인 알칼리성 가수분해가 필히 병행되어야 한다고 생각된다. 결과적으로 단일가수분해 방법을 도입함으로써 식품의 모든 아미노산 정량을 위해 사용되어 오던 3단계 가수분해 과정을 2단계로 간소화할 수 있을 뿐 아니라 6N HCl 가수분해 방법에 비해 훨씬 소량의 산을 사용하고, 가수분해 후 산을 증발시켜야 하는 번거로운 과정이 삭제됨으로써 비용 및 노동력 절감이 기대되며, 아울러 함황아미노산의 회수율이 향상 될 수 있을 것으로 생각된다. For the complete and accurate amino acid determination of protein and food samples, 3 different hydrolysis procedures have been conducted in parallel for each sample, which include the alkaline hydrolysis for tryptophan determination, performic acid oxidation prior to the acid hydrolysis for the determination of cysteine and cystine, and the 6N HCl hydrolysis for the determination of the rest of amino acids. In the present study, amino acid concentrations obtained from the modified single hydrolysis procedure were compared with the values from the conventional hydrolysis procedures in casein and nine food and composite dish samples. In most of the samples tested, the modified single hydrolysis procedure gave significantly higher values of cysteine and cystine compared to the performic acid oxidation method, but resulted in a considerable destruction of tryptophan in food and composite dish samples. There was no consistent difference in the rest of amino acid concentrations between the two hydrolysis systems. Therefore, for complete amino acid determination of various foods and composite dishes, the single hydrolysis method may replace the 6N HCl hydrolysis and performic acid oxidation methods, and thereby reduces 3 hydrolyses to 2 steps with much higher recoveries of the sulfur containing amino acids.

식이내의 단백질과 타우린 함량이 Cysteine 대사에 미치는 영향

박태선 (Park Taesun) 韓國營養學會 1996 Journal of Nutrition and Health Vol.29 No.7

한국인 모유의 지방산 조성과 타우린 농도의 상관관계에 관한 연구

박태선(Park Taesun),정은정(Chung Eun Jung),엄영숙(Um Young Sook),문수재(Moon Soo Jae),이양자(Lee Yang Cha) 韓國營養學會 1998 Journal of Nutrition and Health Vol.31 No.1