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간세포암 환자에서 간동맥화학색전술 후 발생한 간십이지장 누공
박윤혜 ( Yoon Hea Park ),강세훈 ( Se Hun Kang ),김승업 ( Seung Up Kim ),김도영 ( Do Young Kim ),박준용 ( Jun Yong Park ),안상훈 ( Sang Hoon Ahn ),한광협 ( Kwang Hyub Han ),전재윤 ( Chae Yoon Chon ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.3
Transarterial chemoembolization (TACE) is recommended as one of the first line therapy for unresectable hepatocellular carcinoma (HCC). Rupture of HCC following TACE is a rare and potentially fatal complication. We report a case of hepaticoduodenal fistula with ruptured HCC and liver abscess complicated by TACE. A 52-year-old male was treated by TACE three times, followed by radiation therapy and systemic chemotherapy. 30 days after the last TACE, right upper quadrant pain of abdomen was developed. About 1 month later, computed tomography of abdomen showed ruptured HCC with debris containing liver abscess and hepaticoduodenal fistula. Esophagogastroduodenoscopy revealed hepaticoduodenal fistula and hepatic parenchyme covered with exudate. The patient was managed with supportive care, but the hepaticoduodenal fistula persisted. (Korean J Gastroenterol 2011;58:149-152)
다발성 폐전이를 동반한 진행성 간세포암종 환자에서 전신항암화학요법의 치료성적
윤기태 ( Ki Tae Yoon ),최종원 ( Jong Won Choi ),박준용 ( Jun Yong Park ),안상훈 ( Sang Hoon Ahn ),백용한 ( Yong Han Paik ),이관식 ( Kwan Sik Lee ),한광협 ( Kwang Hyub Han ),전재윤 ( Chae Yoon Chon ),김도영 ( Do Young Kim ) 대한간학회 2008 Clinical and Molecular Hepatology(대한간학회지) Vol.14 No.3
이중민 ( Jung Min Lee ),박준용 ( Jun Yong Park ),김도영 ( Do Young Kim ),김경식 ( Kyung Sik Kim ),박영년 ( Young Nyun Park ),김명진 ( Myeong Jin Kim ),전재윤 ( Chae Yoon Chon ),한광협 ( Kwang Hyub Han ) 대한간암연구회 2009 대한간암학회지 Vol.9 No.-
Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis as HCC develops on base of cirrhosis in majority cases, which requires multidisciplinary approach. If feasible, however, surgical resection is the choice of treatment, and many previous studies and guidelines offered appropriate indications for surgical resection; firstly, preservation of liver function should be confirmed with traditional Child-Pugh classification or more recently with Indocyanine Green retention test or absence of portal hypertension. Secondly, several variables about the size, number, and vascular invasion of tumor should be taken into consideration. It is suggested that to lessen the risk of recurrence gross vascular invasion be absent and the number of tumor be single. Regarding the size of tumor, although risk of dissemination increases with size, some tumors may grow as a single mass and thus the size of tumor is not a clear-cut limiting factor. Based on above suggestions, we herein offer our experience of a patient with initial hopeful expectation of good outcome with surgical resection, but who eventually turned out to result in disseminated tumor recurrence. Further study, maybe regarding a combination of adjuvant or neoadjuvant transarterial chemoembolization/chemotherapy or radiotherapy, is necessary on how to manage such patient.