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김세라,강현구,오기석,박인철,박상국,김성호,손창호,Kim, Se-ra,Kang, Hyun-gu,Oh, Ki-seok,Park, In-chul,Park, Sang-guk,Kim, Sung-ho,Son, Chang-ho 대한수의학회 2000 大韓獸醫學會誌 Vol.40 No.2
Serial ultrasonographic examinations were performed on pregnant Korean Jindo bitches. Measurements of inner chorionic cavity diameter and fetal head diameter were made from pregnancy day 15 to parturition. These measurements were converted retrospectively based on the day of parturition (day 0). The data of inner chorionic cavity diameter obtained from day -42 to day -25 and fetal head diameter obtained from day -24 to day -1 were used to prediction of parturition day. Formulas for the prediction of parturition day using the method of least squares were derived. These formulas were then used to predict parturition dates based on single measurements of inner chorionic cavity diameter or fetal head diameter in 17 additional pregnant Korean Jindo bitches. Predicted date of parturition was then compared to actual whelping date. In the prediction of parturition based on inner chorionic cavity diameter, 7 of 10 bitches were coincided prediction date and actual whelping date, and the prediction was accurate to within 1 day in 3 of 10 bitches. The prediction of parturition based on fetal head diameter was accurate to within 1 day in 6 of 7 bitches and within 2 days in 1 of 7 bitches. In conclusion, the ultrasound measurement of inner chorionic cavity diameter and fetal head diameter are practical and accurate tool in the prediction of parturition.
방사선 조사 마우스에서 분죽(Phyllostachys nigra var. henenis Strapf)잎 추출물의 효과
신동호,김종춘,김세라,오헌,박인철,오기석,정희종,장종식,김성호,Shin, Dong-Ho,Kim, Jong-Choon,Kim, Se-Ra,Oh, Heon,Park, In-Chul,Oh, Ki-Seok,Chung, Hee-Jong,Jang, Jong-Sik,Kim, Sung-Ho 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.1
This study was performed to determine the effect of Phyllostachys nigra var. henenis Strapf leaf extract on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-radiation. Phyllostachys nigra var. henenis Strapf administration before irradiation (I.P.: 125 mg/kg of body weight, at 24 hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.01). The frequency of radiation-induced apoptosis was also reduced by pretreatment of Phyllostachys nigra var. henenis Strapf (I.P.: 280 mg/kg or 28 mg/kg of body weight, at 24 hours before irradiation, p<0.01). These results indicated that Phyllostachys nigra var. henenis Strapf might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of Phyllostachys nigra var. henenis Strapf and its components.
고선량 및 저선량 방사선 조사 마우스에서 누에동충하초(Paecilomyces japonica)의 효과
김세라,오헌,이해준,신동호,김종춘,박인철,오기석,조성기,김성호,Kim, Se-ra,Oh, Heon,Lee, Hae-june,Shin, Dong-ho,Kim, Jong-choon,Park, In-chul,Oh, Ki-seok,Jo, Sung-kee,Kim, Sung-ho 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.2
Cordyceps has a reputation for its broad biological activities and as a tonic which replenishs vital function in Chinese traditional medicines. As an attempt to obtain fundamental data for the development of new type Cordyceps, the effects of the fruiting bodies of cultivated fungus of Paecilomyces japonica grown on silkworm larvae on radiationinduced damages were investigated. We performed this study to determine the effect of Dongchongxiacao (Paecilomyces japonica) on jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells and hair follicles of mice irradiated with high and low dose of gamma-radiation. Treatment with Dongchongxiacao showed no significant modifying effects on the jejunal crypt survival and endogenous spleen colony formation. The frequency of radiationinduced apoptosis was reduced by pretreatment of Dongchongxiacao (i.p.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.01). The spontaneous levels of apoptotic cells are $0.082{\pm}0.041$ in intestinal crypts and $0.231{\pm}0.084$ per hair follicle section of skin. Pretreatment of Dongchongxiacao was associated with decreases of 26.86% in intestinal crypt and 66.36% in hair follicle decrease in the number of cells with nuclei positively stained for apoptosis compared with the irradiation control group. We demonstrated for the first time that Dongchongxiacao administration could reduce the extent of apoptosis produced by radiation in the hair follicle. The results presented herein that Dongchongxiacao given before irradiation is capable of reducing the severity of cell loss as a result of apoptosis.
김세라,김태환,이해준,오헌,조성기,오기석,박인철,손창호,김성호,Kim, Se-Ra,Kim, Tae-Hwan,Lee, Hae-Jun,Oh, Heon,Cho, Sung-Ki,Oh, Ki-Seok,Park, In-Chul,Son, Chang-Ho,Kim, Sung-Ho 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.3
Cytogenetic and hematological analysis was performed in peripheral blood from the Korean native goat bred in the nuclear power plant (Wolsong and Uljin) and control area. The frequency of micronuclei (MN) in peripheral blood lymphocytes from goat was used as a biomarker of radiobiological effects resulting from exposure to environmental radiation. An estimated dose of radiation was calculated by best fitting linear-quadratic model based on the radiation-induced MN data over the range from 0 to 4 Gy from the goat lymphocytes with in vitro irradiation. MN rates in goats from the Wolsong and Uljin nuclear power plant, and control area were 9.60/1000, 6.83/1000 and 9.88/1000, respectively. There were no significant differences in MN frequencies and hematological values in goats between nuclear power plant and control area. High level of platelet in the goat from Uljin nuclear power plant was observed, which seemed to be related to the goat management.
Shih-tzu견에서 초음파 검사에 의한 분만일 예시표 확립
김방실,고진성,이순애,조양택,김재풍,오기석,김종택,박인철,김영홍,손창호,Kim, Bang-sil,Ko, Jin-sung,Lee, Sun-ae,Cho, Yang-tak,Kim, Jae-pung,Oh, Ki-seok,Kim, Jong-taek,Park, In-chul,Kim, Young-hong,Son, Chang-ho 대한수의학회 2004 大韓獸醫學會誌 Vol.44 No.2
To establish a prediction table of parturition day real-time B-mode ultrasonographic examinations were performed in 12 pregnant Shih-tzu bitches. Measurement of inner chorionic cavity diameter and fetal head diameter was performed from 15 days of gestation to parturition. These were converted retrospectively based on the day of parturition (Day 0). The data of inner chorionic cavity diameter obtained from Day -44 to Day -25 and fetal head diameter obtained from Day -25 to Day -1 were used to compile a prediction table of parturition day. The 22 pregnant Shih-tzu with unknown mating time were examined to assess an accuracy of the table established in this study. And these results were applied to the prediction of parturition day and compared to actual parturition day. Parturition day prediction based on the inner chorionic cavity diameter and fetal head diameter was 100% accurate within ${\pm}2$ days. In addition, the accuracy for parturition day within 0, ${\pm}1$, and ${\pm}2$ days interval using the prediction table of parturition day were 68, 82, and 100%, respectively. Therefore, the prediction table of parturition day seems to be a useful tool for the prediction of parturition day in practice.
독실라민 중독시 발생할 수 있는 발작의 특성과 위험인자
송범수 ( Beom Soo Song ),이기만 ( Ki Man Lee ),김선욱 ( Sun Wook Kim ),유제성 ( Je Sung You ),정태녕 ( Tae Nyung Chung ),박유석 ( Yoo Seok Park ),정성필 ( Sung Phil Jung ),구홍두 ( Hong Du Goo ),박인철 ( In Cheol Park ) 대한임상독성학회 2010 대한임상독성학회지 Vol.8 No.2
Purpose: Doxylamine is antihistamine drug that is used as a hypnotic. It is also used for suicidal attempts because it can be easily purchased at the pharmacy without a prescription. There were many articles about the complications after doxylamine intoxication such as a rhabdomyolysis, but only a few articles have reported on seizure. We reviewed the cases of doxylamine intoxication with seizure that were treated in the emergency department. Methods: We reviewed the medical records of the patients who were over 15 years old and who were intoxicated by doxylamine at 3 emergency medical centers from January 2006 to June 2010. We reviewed the patients’age, gender, the dose of doxylamine ingested, if gastrointestinal decontamination was done, the time from intoxication to hospital arrival, the seizure history, treatment of seizure, the electroencephalography (EEG) results, the brain computed tomography (CT) results and the blood test results. Results: There were 168 patients who were intoxicated by doxylamine during the study period. Twelve patients had a seizure episode. The differences between the patients who developed seizure and the patients who did not were the dose and the serum levels of sodium and creatinine. The only clinically meaningful difference was the amount of doxylamine. The amount of doxylamine ingested (>29 mg/kg) predicted the development of seizure with a sensitivity of 75% and a specificity of 92% on the ROC curve. One patient among the seizure patients expired in the emergency department. Conclusion: In case of doxylamine intoxicated patients, there is close relationship between seizure and ingested amount, so close observation needs to be done for the patients who ingest too much because doxylamine can cause death. Further prospective studies are needed for doxylamine intoxicated patients with a seizure episode.
석순자 ( Soon Ja Seok ),진용주 ( Yong Ju Jin ),유기범 ( Ki Bum Yoo ),권순우 ( Soon Woo Kwon ),박인철 ( In Cheol Park ),이상엽 ( Sang Yeob Lee ),김양섭 ( Yang Sup Kim ) 한국균학회 2014 韓國菌學會誌 Vol.42 No.4
This survey was conducted in order to clarify the species diversity and distribution of mushrooms at Worldcup Park in Seoul, from May to November 2010 and 2014. In the survey, a total of 98 taxa, 98 species, 86 genera, 38 families, 12 orders, three classes, and two phyla were identified. A total of 250 specimens of Mushrooms were collected from Pyonghwa Park and 63 species, 71 genera, 36 families, 13 orders, three classes, and two phyla were identified. Coprinus atramentarius and Psathyrella candolleana were high in frequency, as ten times and nine times, respectively. In Noeul Park, 102 specimens were collected, 41 species, 42 genera, 19 families, 19 orders, two classes, and two phyla were identified. In Noeul Park mostly layed with lawn, Agrocybe semiorbicularis and Agaricus campestris were high in frequency, as ten times and nine times, respectively. There were no mushrooms in succession during three years. In Haneul Park, a total of 128 specimens of mushrooms were collected. 49 species, 57 genera, 30 families, 11 orders, three classes, and two phyla were identified. Agrocybe semiorbicularis and Phallus rugulosus were high in frequency, as four times. In Nanjicheon Park, a total of 68 specimens of mushrooms were collected. 31 species, 34 genera, 30 families, nine orders, one class, and one phylum were identified. Coprinus atramentarius and Psathyrella velutina were high in frequency, as three times. Investigation on the diversity of mushrooms at the Worldcup Park, piled up with the city``s waste, will be of the great significance in the aspect of the ecological change. All specimens examined in this work are preserved in HCCN (Herbarium Conservation Center of National Academy of Agricultural Science).