http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
우슬(牛膝)의 콜라겐 유도 관절염 생쥐에 대한 개선 효과
박용기 ( Yong Ki Park ),김창수 ( Chang Soo Kim ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.4
Objectives: The present study was undertaken to determine whether the water extract of Achyranthis Radix, which is the roots of Achyranthes japonica (Achyranthis Radix, AR), is efficacious against collagen-induced arthritis (CIA) in DBA/1J mice. Methods: Mice were immunized with bovine type Ⅱ collagen and orally treated with AR-W (50 and 100㎎/㎏/bw) from days 21 to 42 after immunization. Arthritis was evaluated by arthritic score, histological examination of knee joint and serological markers such as TNF-a, PGE2 and anti-type II collagen (CⅡ)IgG. Results: The results showed that comparing with untreated CIA mice, treated with AR-W significantly suppressed the clinical score and joint tissue pathological damages, reduced the serum levels of TNF-a, PGE2 and anti-CⅡ IgG in CIA-mice. These results suggest that AR-W can effectively alleviate inflammatory response on CIA, and anti-inflammatoy of AR-W can be attributed, at least partially, to the inhibition of inflamamtory mediators, PGE2 and TNF-a, in CIA. Conclusions: This study suggests that AR-W has a therapeutic potential in inflammatory joint diseases such as rheumatoid arthritis.
WHW(R)의 랫드에서의 반복경구투여 독성에 관한 연구
박용기 ( Yong Ki Park ),오태우 ( Tae Woo Oh ),배효상 ( Hyo Sang Bae ),윤철호 ( Cheol Ho Yoon ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.3
Objectives: We investigated the repeated-dose toxicity of Wenpitang-Hab-Wulingsan(WHW), a Korean traditional medicine prescribed with twelve herbs, which has been used for the treatment of renal disease. Methods: WHW extract prepared by GLP company. WHW was supplemented by gavage at 0, 100, 500 and 1000㎎/㎏/day for 13-week consecutive days. We recorded the clinical signs of toxicity, body weight, organ weights, hematology, gross and histological changes in target organs rats and clinical chemistry analysis for all rats. Results: WHW extract at all doses was shown no mortality or abnormal clinical signs in rats during at the observation period. Furthermore, there was no difference in body weight and food-take consumption, organ weight, gross pathological findings, and urine analysis among the groups of rats treated with different doses of WHW extract. The hematological analysis and clinical blood chemistry data were revealed no toxic effects from WHW-treated rats. Conclusions: The results suggest that WHW extract in rats is a wide margin of safety on a acute toxicity.
블록 근사화식의 적응적 선택을 이용한 프랙탈 영상 부호화
박용기(Park Yong Ki),박철우(Park Chul Woo),김두영(Kim Doo Young) 한국정보처리학회 1997 정보처리학회논문지 Vol.4 No.12
This paper suggests techniques to reduce coding time which is a problem in traditional compression and improve fidelity of reconstructed images by determining fractal coefficient through adaptive selection of block approximation formula. First, to reduce coding time, we construct a linear list of domain blocks of which characteristics is given by their luminance and variance and then we control block searching time according to the first permissible threshold value. Next, when employing three-level block partition, if a range block of minimum partition level cannot find a domain block which has a satisfying approximation error, we choose new approximation coefficients using a non-linear approximation of luminance term. This boosts the fidelity. Our experiment employing the above methods shows enhancement in the coding time more than two times over traditional coding methods and shows improvement in PSNR value by about 1-3dB at the same compression rate.