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후방경유 요추 융합수술시 척추후관절낭 손상의 운동역학적 영향
박승원,김영백,황성남,최덕영,권정택,민병국,석종식,Park, Seung Won,Kim, Young Baeg,Hwang, Sung Nam,Choi, Duck Young,Kwon, Jeong Taik,Min, Byung Kook,Suk, Jong Sik 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.3
Objectives : Although posterior lumbar fusion operations had been reported to accelerate spinal degeneration, there have been only a few studies for their biomechanical effects. We have studied the change of motion range at the vertebral joint one level above the fusion(UVJ) in pedicle screw fixation group(PSF)(n=13) where facet capsule was destroyed and in posterior lumbar interbody fusion group(PLIF)(n=8) where it was spared. Patients and Methods : The patients were divided into early(3 to 6 months) and late(over 12 months) according to postoperative follow-up period. The flexion, extension and flexion-extension angles(FA, EA, FEA) were measured at the UVJ with pre-operative, early and late post-operative films. Results : Mean age and male to female ratio were $52.7{\pm}9.3$ and 1 : 3.2. Mean follow-up periods were $144.1{\pm}30.0$ and $528.8{\pm}160.3$ days in early and late groups, respectively. The FEA and FA in the late PSF($11.8{\pm}3.1$, $8.5{\pm}2.9$) were significantly greater than pre-operative angles($7.8{\pm}3.9$, $5.1{\pm}3.7$)(p<0.01, p<0.05). All angles in the PLIF showed no significant changes with time. The FEA and FA in the late PSF($11.8{\pm}3.1$, $8.5{\pm}2.9$) were significantly greater than those of the late PLIF($7.6{\pm}2.3$, $3.4{\pm}2.0$)(p<0.01, p<0.001). All angles at early follow-up period were similar between PSF and PLIF. The EA showed no significant change in relation with follow-up period or fusion method. Conclusion : As a result, the facet capsule injury in pedicle screw fixation seems to be related with increased flexion angle or degeneration of the adjacent joint above the fused vertebra in the late phase.
경피적 전기 신경 자극의 적용 부위에 따른 자율신경계 활성도 변화 비교 및 평가
박승원,최준원,정면규,이강인,김한성,Park, Seung Won,Choi, Jun Won,Jeong, Myeon Gyu,Lee, Kang In,Kim, Han Sung 대한의용생체공학회 2021 의공학회지 Vol.42 No.3
Purpose: The aim of this study is to find the location of acupoints that are effective for increasing parasympathetic nervous system(PNS) activity among acupoints used to relieve symptoms such as dizziness and nausea. Materials and Methods: Twenty healthy adult men participated in this experiment. Transcutaneous electrical nerve stimulation(TENS) was applied to P6(Neiguan), ST36(Zusanli) and BL20(Pishu) for 30 minutes. For 5 minutes before and after stimulation, Electrocardiogram(ECG), Electrodermal activity(EDA), Respiration, and Skin temperature(SKT) were measured using biosignalsplux Professional(biosignalsplux; Portugal). Paired t-test was performed for the results before and after stimulation, and a one-way ANOVA test between stimulations was performed for the rate of change before and after stimulation. Results: When each acupoint was stimulated with TENS, it was found that the PNS was generally activated. In addition, when considering the change in biosignals after stimulation, the participants stimulated with P6 showed the most consistent results. Conclusion: As a result of stimulating each acupoint, it was found that stimulating P6 can effectively increase PNS activity. These results indicate that methods of stimulating P6 may be most effective in alleviating symptoms of motion sickness.
멀미 완화를 위한 비침습적 및 비약리적 방법 비교 및 평가
박승원,최준원,남상훈,최여은,이강인,정면규,신태민,김한성,Park, Seung Won,Choi, Jun Won,Nam, Sanghoon,Choi, Yeo Eun,Lee, Kang In,Jeong, Myeon Gyu,Shin, Tae-Min,Kim, Han Sung 대한의용생체공학회 2021 의공학회지 Vol.42 No.5
Purpose: The purpose of this study is to present a way to alleviate motion sickness(MS) by stimulating acupoint through PEMFs, and to assess the effectiveness of PEMFs against stimulation previously used to stimulate acupoint using biosignal evaluations and surveys. Materials and Methods: Thirteen healthy men participated in the experiment. MS was induced in the participants, and MS relief stimulation was applied for 30 minutes. There were 4 types of MS relief stimulation, and Sham, Reliefband, Transcutaneous electrical nerve stimulation(TENS), and Pulsed electromagnetic fields stimulation(PEMFs) were used. The biosignals were measured during 30 minutes of applying MS relief stimulation, and the symptoms of MS were evaluated through a questionnaire survey. The measured biosignals are Electrocardiogram(ECG), Electrodermal activity(EDA), Respiration, Skin temperature(SKT), and Electrogastrogram(EGG). A one-way ANOVA test was performed for the rate of change by stimulation for MS relief over time. Results: Participants who were stimulated had a sharp decrease in MS symptoms. Biosignals were analyzed to evaluate autonomic nervous system activity, and the parasympathetic nervous system could be activated through stimulation. Conclusion: TENS and PEMFs were more effective in relieving MS symptoms than Reliefband. It is believed that PEMFs will be effective in consideration of the comfort of participants to be applied to actual vehicles, and studies to further verify the effects of PEMFs on MS should be conducted.
모바일 환경에서 HEVC 인트라 인코딩의 계산 복잡도 감소를 위한 영상 특성 기반의 블록 후보 조기 결정 방법
박승원,이채은,Park, Seung-Won,Rhee, Chae Eun 대한임베디드공학회 2016 대한임베디드공학회논문지 Vol.11 No.4
Compared to the former H.264 standard, the number of the prediction modes has highly increased in HEVC intra prediction. Compression efficiency and accurate prediction are significantly improved. However, the computational complexity increases as well. To solve this problem, this paper proposes the new scheme where not only prediction modes but also block partition candidate are early chosen. Compared to the original intra prediction in HEVC, the proposed scheme achieves about 38% reduction in processing cycles with a marginal loss in compression efficiency.
Characterization of the Promoter Controling the Stage-Specific Gene Expression of Bombyx mori
박승원(Seung-Won Park),최광호(Gwang-Ho Choi),구태원(Tae-Won Goo),김성렬(Seong Ryul Kim),강석우(Seok-Woo Kang) 한국생명과학회 2011 생명과학회지 Vol.21 No.10
본 연구에서는 누에의 초기 배아시기에 유전자 발현 조절이 가능한 EEG-704 promoter를 개발하고자 하였다. Promoter의 핵심 영역을 결정하기 위하여, 10개의 서로 다른 partial mutant clone들을 만들고 이를 Sf9 곤충세포주에 도입하여 luciferase assay 방법을 사용하여 각각의 clone의 활성을 분석하였다. Constitutive promoter인 BmA3 promoter에 의한 활성과 비교하였을 때, 약1.5 kb의 promoter 염기서열을 포함하는 clone이 가장 높은 luciferase 발현율을 나타내었다. 특히 EEG-704 유전자의 경우 BLAST를 이용한 유전자 비교·분석의 결과 누에의 열충격 단백질 20.8 (BmHsp20.8) 과 동일한 것으로 밝혀졌으며, 정상 온도조건과 비교하였을 때 열충격을 가한 조건하에서 발현율이 증가하는 현상을 나타내었다. 특이적으로 발생단계에서 직·간접적으로 발현 조절이 가능한 이러한 promoter는 여러 유용 재조합 단백질 생산을 위한 형질전환 누에 개발 시 매우 유용할 것으로 생각된다 We characterized embryo early gene (EEG)-704 promoter of the silkworm Bombyx mori, which is specifically regulated in the development stages. To determine core promoter region, 10 different partial mutant clones were tested by luciferase assay in Sf9 cells. About 1.5 kb promoter shows higher luciferase activity than constitutive promoter (BmA3). Interestingly, EEG-704 shares the same DNA sequences with BmHsp20.8 by the result of BLAST analysis; its expression is also increased under heat shock condition. Development of such promoter inducible, directly or indirectly in the developmental-stage, is very useful in making recombinant proteins in transgenic silkworms.
두 개의 인덕터를 갖는 PV-MIC용 준공진 부스트 컨버터
박승원(Seung-Won Park),김재형(Jae-Hyung Kim),김준구(Jun-Gu Kim),류동균(Dong-Kyun Ryu),김태훈(Tae-Hoon Kim),원충연(Chung-Yuen Won) 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.11
This paper proposed a new zero-voltage switching(ZVS) Two-Inductor boost converter. The conventional Two-Inductor boost converter has defect. When the switch is turned off, the high voltage spike is occurred in the switch by leakage inductance and switch parasitic capacitor. To solve this problem, the parallel resonant capacitor is added to the conventional Two-Inductor boost converter. Using quasi-resonant between parallel resonant capacitance and leakage inductance, the switches is operated soft switching. A reduction of transformer turn ratio is achieved by the voltage doubler rectifier.
스위치 스트레스 저감이 가능한 소프트 스위칭 부스트 컨버터
박승원(Seung-Won Park),김준구(Jun-Gu Kim),김재형(Jae-Hyung Kim),엄주경(Ju-Kyoung Eom),원충연(Chung-Yuen Won),정용채(Yong-Chae Jung) 전력전자학회 2009 전력전자학술대회 논문집 Vol.2009 No.2
This paper proposed a soft switching boost converter with an auxiliary circuit, and a modified control method for reduction of switch stress. The proposed converter applies an auxiliary circuit, which is added to the conventional boost converter and used to achieve soft switching for both a main switch and an auxiliary switch. The auxiliary circuit consist of a resonant inductor and two capacitors, an auxiliary switch. The main switch is operated ZVS turn-on, turn-off also auxiliary switch is operated ZCS turn-on, ZVS turn-off. The proposed soft switching boost converter has lower switch loss and higher efficiency than conventional soft switching boost converter.