니오솜을 이용한 [³H]아시클로버의 경피투과

박새해,이순영,용철순 영남대학교 약품개발연구소 1998 영남대학교 약품개발연구소 연구업적집 Vol.8 No.-

Niosomes are vesicles formed from synthetic non-ionic surfactants, offering an alternative to chemically unstable and expensive liposomes as a drug carrier. Non-ionic surfactant and cholesterol mixture film leads to the formation of vesicular system by hydration with sonication method. The formation of niosome was ascertained by negative staining of TEM. The entrapment efficiency of niosomal suspension was gradually increased with increasing the ratio of cholesterol to surfactant. It was found that the niosome with 6 : 4 (polyoxyethylene 2-cetyl ether : cholesterol) ratio was more stable than those with other ratios. The topical application of acyclovir(ACV) in the treatment of herpes simplex virus type 1(HSV-1) skin disease has a long history. There are an increasing number of reports, however, in which topical ACV therapy is not as effective as oral administration. Lack of efficacy with topical ACV has been hypothesized to reflect the inadequate delivery of drug to the skin. We investigated the permeation of niosome containing [³H]ACV in hairless mouse skin using Franz diffusion cell model. Permeation coefficient(P) of aqueous ACV was 6.7×10^(-4) (cm/hr) and that of ACV in niosome was 23.4×10^(-4) (cm/hr), suggesting about 3.5 times increase in the transdermal permeation.

팔작지붕의 측면서까래 결구방법에 대한 연구

박새암(Park, Sae-Am),한지만(Han, Ji-Man) 대한건축학회 2017 대한건축학회 학술발표대회 논문집 Vol.37 No.2

국어교육,한국어교육 : 근대 한국어 신문 읽기 교재의 내용과 구성 -『NEWSPAPER READING For Beginners(1939)』에 대하여-

박새암 ( Sae Am Park ) 한성대학교 한성어문학회 2015 漢城語文學 Vol.34 No.-

본 연구는 근대 한국어교육 형성기에 이루어진 한국어 신문 읽기 교육의 구체적인 모습을 확인하고자 1939년에 출간된 한국어 교재인 『NEWSPAPER READING For Beginners』의 체제와 내용을 분석한 것이다. 먼저 2장에서는 아직까지 학계에 보고된 바 없는 『NEWSPAPER READING For Beginners』가 한국어교육사에서 어떤 위상을 가지는지 알아보기 위해 저자와 발행기관을 중심으로 살펴본 후, 3장에서는 교재의 체제와 내용을 기본 체제, 단원구성 방식, 교육 내용으로 나누어 고찰해 보았다. 『NEWSPAPER READING For Beginners』는 개신교 선교사들을 위한 한국어 교육기관이었던 ‘The Korean Language School’에서 개발된 것으로 이 학교의 교장을 역임하기도 하였던 선교사 Charles. A. Sauer가 저술한 것이다. 이 책은 신문 읽기라는 특정한 교육 목적의 달성을 위해 체계적·계획적으로 고안된 최초의 한국어 읽기 교육용 교재라는 점에서 의미가 있다. 『NEWSPAPER READING For Beginners』의 기본 체제는 저자의 서문과 10개의 본 단원과 2개의 추가 단원, 기초 한자의 적요표(摘要表), 부수 활용법, 부수 일람표로 이루어져 있다. 단원 구성상의 특징을 살펴보면 전체단원 구성에서는 주제별로 단원 구성을 하고 있으며, 기사문과 비기사문이라는 교육 내용 범주에 따라 단원 구성에 차이를 두고 있음이 확인된다. 개별 단원의 구성에서는 문자, 단어, 구절의 순으로 학습 단위를 단계적으로 확장하는 제시 방식과 단원 안내, 활동 및 과제 제시를 위한 메타텍스트의 활용을 통해 실제 교수·학습을 고려한 언어 교재로서의 체계적인 단원 구성을 하고 있음을 알 수 있다. 또한 교재에서는 신문을 읽기 위한 기초적인 한자와 한자어의 학습, 신문이 가지는 전형적인 표현 양식의 연습이라는 두 층위의 교육을 통해 신문 읽기라는 본질적인 교육 목표를 달성하기 위해 교육 내용을 조직하고 있음을 확인할 수 있다. This research analyzes the system and context of 『NEWSPAPER READING For Beginners』, a Korean textbook published in 1939, to find out the concrete situation of Korean newspaper reading education during modern Korean language education formation period. First, on the 2nd chapter, the writer and publisher was mainly studied to find out what state 『NEWSPAPER READING For Beginners』, a Korean textbook that is not yet reported on the field of studies, was in Korean education history. Then on the 3rd chapter, the system and context was considered divided into basic system, chapter composition, and context composition. 『NEWSPAPER READING For Beginners』 is written by missionary Charles. A. Sauer who was also the principal of ‘Korean Language School’, a Korean education organization for Protestant missionaries, and it was developed with the purpose to be used as the textbook in this school. This book has its meaning that it is the first Korean reading education textbook developed with plans and system to achieve a specific educational purpose which was to read newspaper. The basic system of 『NEWSPAPER READING For Beginners』 is constituted of the introduction of the writer, main context of 10 main chapters and 2 complimentary chapters, and appendix of Chinese letter abstract table, radical application, and radical table. The characteristic of chapter composition, the whole chapter composition is made according to the theme and the chapter composition differs according to the education category whether it is article or non-article. The individual chapter composition is systematic as linguistic text book considering the actual lecturing and teaching through the presentation method expanding the learning unit phase to phase in the process of letter, word, and phrase and application of meta text for introduction, activity, and assignment suggestion. The context composition can be divided into vocabulary education and reading education. The vocabulary education category is the prerequisite for reading education category and its education context is constituted in terms of ‘learning’ and the reading education category is constituted in terms of ‘practicing’ with the basis of what was learned in vocabulary education category.

점상출혈 및 면화반에서 비롯된 국소망막신경섬유층결손의 진행 2예

박새미,하승주 순천향대학교 순천향의학연구소 2011 Journal of Soonchunhyang Medical Science Vol.17 No.2

We report two cases of progressive localized retinal nerve fiber layer (RNFL) defect following cotton wool spots and a dot hemorrhage,63-year-old woman with RNFL defect in inferior temporal retina of the right eye and 43-year-old man with RNFL defect in superior temporal retina of the right eye. Case 1 showed a dot hemorrhage adjacent to RNFL defect in the right eye and a new slit-like localized RNFL defect in the left eye 5 months later. The visual field in the left eye demonstrated corresponding field defect 9 months later. Case 2 showed a slit-like RNFL defect starting from cotton wool spots in the right eye and corresponding visual field defect. Cotton wool spots and dot hemorrhages represented ischemic damages at the nerve fiber layer. Two noticeable cases showed the progression of RNFL defect caused by repetitive localized microvascular ischemic events, resulting in visual field loss.

24층 건물의 연쇄붕괴 저항성능평가

박새로미(Park Sae-Ro-Mi),권광호(Kwon Kwang-Ho),강현구(Kang Hyun-Goo),김진구(Kim Jin-Koo) 대한건축학회 2011 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.31 No.2(구조계)

In this study the progressive collapse resisting capacity of a tall building structure was evaluated and its collapse behavior was studied. The analysis model is a twenty four story reinforced concrete structure, and the progressive collapse resisting capacity was evaluated by the modified linear static analysis procedure which was developed using the nonlinear static analysis procedure. For verification of the analysis procedure, the nonlinear static and dynamic analyses were carried out and their results were compared.

변화 없음의 변화

박새봄 새얼문화재단 2013 황해문화 Vol.81 No.-

<북장로회> 한국 선교부의 초기 한국어교육 연구

박새암 ( Park Saeam ) 성신여자대학교 인문과학연구소 2017 人文科學硏究 Vol.35 No.-

This study is an examination of the Korean language learning of the early Protestant missionaries, which was not revealed in the previous discussion, based on the records of the `Presbyterian Church U.S.A. (PCUSA)` Korea Mission. Missionaries from the `PCUSA` sent to Korea held an annual banquet where mission activities were reported, and in those reports were left records related to Korean language learning by missionaries. As a result, it was confirmed that Korean language learning was conducted mainly by the Language Committee in the Mission. The Language Committee regularly assessed the Korean language skills of missionaries and reported them to the Mission Board. In addition, senior and junior missionaries were divided into two groups based on their Korean ability. The Language Committee has been responsible for managing the Korean language learning of the missionaries by appointing the supervisors in each mission area. The Language Committee developed and used the `Korean Language Learning Course,` which is an evaluation tool for the evaluation of Korean language ability and a guideline for Korean language learning. This was the best educational choice that focused on `learning` in the situation when collective teaching and learning was difficult due to locale and time constraints. Therefore, it was confirmed that the Korean language learning of the Protestant missionaries in the late 19th and early 20th centuries was done within the active control of the Mission rather than the individual missionary.

Hyaluronic Acid Multilayer Films Capturing Nanocarriers for Drug Delivery Platforms

박새봄,나완근,서진화,방석호,김병수,차국헌 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.1

Preparation of glass cloth reinforced polymer composite with organic- inorganic hybrid polymer

박새미,조남주,김혜현 한국고분자학회 2015 한국고분자학회 학술대회 연구논문 초록집 Vol.2015 No.4

Perovskite-based solar cell fabrication for large area with low material wastage and uniform film thickness

박새미,노용진,서유현,최철문,나석인 한국고분자학회 2015 한국고분자학회 학술대회 연구논문 초록집 Vol.2015 No.4